Rodney J Schlosser

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. doi request reprint Subcutaneous and sublingual immunotherapy for allergic rhinitis: what is the evidence?
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia, USA
    Am J Rhinol Allergy 26:18-22. 2012
  2. ncbi request reprint Image-guided procedures of the skull base
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, P O Box 250550, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 38:483-90. 2005
  3. ncbi request reprint Nasal cerebrospinal fluid leaks: critical review and surgical considerations
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, 135 Rutledge Ave, Suite 1130, PO Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Laryngoscope 114:255-65. 2004
  4. doi request reprint Surgical salvage for the non-functioning sinus
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 43:591-604, ix-x. 2010
  5. ncbi request reprint Endoscopic resection of sinonasal hemangiomas and hemangiopericytomas
    Rodney J Schlosser
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 68:69-72. 2006
  6. doi request reprint Alterations in gene expression of complement components in chronic rhinosinusitis
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol Allergy 24:21-5. 2010
  7. ncbi request reprint Endoscopic management of cerebrospinal fluid rhinorrhea
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, PO Box 250550, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 39:523-38, ix. 2006
  8. doi request reprint Mucosal expression of nerve growth factor and brain-derived neurotrophic factor in chronic rhinosinusitis
    Charles S Coffey
    The Medical University of South Carolina, Department of Otolaryngology Head and Neck Surgery, Charleston, South Carolina 29425, USA
    Am J Rhinol Allergy 23:571-4. 2009
  9. ncbi request reprint Cerebrospinal fluid pressure monitoring after repair of cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 130:443-8. 2004
  10. doi request reprint Increased presence of dendritic cells and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis
    Chris M Ayers
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Int Forum Allergy Rhinol 1:296-302. 2011

Detail Information

Publications91

  1. doi request reprint Subcutaneous and sublingual immunotherapy for allergic rhinitis: what is the evidence?
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia, USA
    Am J Rhinol Allergy 26:18-22. 2012
    ..S. Food and Drug Administration at this time. The similarities and differences between SLIT and SCIT are often discussed, yet clinical studies directly comparing these immunotherapy methods are scarce...
  2. ncbi request reprint Image-guided procedures of the skull base
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, P O Box 250550, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 38:483-90. 2005
    ..Continued advances in endoscopic equipment, radio-graphic techniques, and IGS systems will permit the rhinologist to continue to stretch the minimally invasive boundaries in treating skull base pathology...
  3. ncbi request reprint Nasal cerebrospinal fluid leaks: critical review and surgical considerations
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, 135 Rutledge Ave, Suite 1130, PO Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Laryngoscope 114:255-65. 2004
    ..This review article will highlight the history, physiology, pathophysiology, diagnosis, surgical techniques, and postoperative care relevant to nasal CSF leaks and encephaloceles...
  4. doi request reprint Surgical salvage for the non-functioning sinus
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 43:591-604, ix-x. 2010
    ..This latter option seems to represent the best long-term chance for surgical success in these difficult cases, with repeat ablative procedures as a last resort...
  5. ncbi request reprint Endoscopic resection of sinonasal hemangiomas and hemangiopericytomas
    Rodney J Schlosser
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 68:69-72. 2006
    ..There are limited case reports of endoscopic resection of benign vascular tumors, including hemangiomas, or those with low-grade malignant potential, such as hemangiopericytomas...
  6. doi request reprint Alterations in gene expression of complement components in chronic rhinosinusitis
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol Allergy 24:21-5. 2010
    ....
  7. ncbi request reprint Endoscopic management of cerebrospinal fluid rhinorrhea
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Suite 1130, PO Box 250550, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 39:523-38, ix. 2006
    ..This article highlights the history, physiology, pathophysiology, diagnosis, surgical techniques, and postoperative care relevant to nasal cerebrospinal fluid leaks and encephaloceles...
  8. doi request reprint Mucosal expression of nerve growth factor and brain-derived neurotrophic factor in chronic rhinosinusitis
    Charles S Coffey
    The Medical University of South Carolina, Department of Otolaryngology Head and Neck Surgery, Charleston, South Carolina 29425, USA
    Am J Rhinol Allergy 23:571-4. 2009
    ..This study was designed to examine the expression of two potent neurotrophins, nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF), in CRS...
  9. ncbi request reprint Cerebrospinal fluid pressure monitoring after repair of cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 130:443-8. 2004
    ..To measure intracranial pressures (ICPs) via lumbar drains after surgical repair of cerebrospinal fluid (CSF) leaks...
  10. doi request reprint Increased presence of dendritic cells and dendritic cell chemokines in the sinus mucosa of chronic rhinosinusitis with nasal polyps and allergic fungal rhinosinusitis
    Chris M Ayers
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Int Forum Allergy Rhinol 1:296-302. 2011
    ..Once DC presence was established we considered possible mechanisms for DC recruitment to the sinuses...
  11. pmc Patient-centered decision making in the treatment of chronic rhinosinusitis
    Zachary M Soler
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U S A
    Laryngoscope 123:2341-6. 2013
    ..To explore possible factors that might impact a patient's choice to pursue endoscopic sinus surgery (ESS) or continue with medical management for treatment of refractory chronic rhinosinusitis (CRS)...
  12. doi request reprint Human sinonasal epithelial cells direct dendritic function and T-cell T helper 1/T helper 2 skewing following Aspergillus exposure
    Jennifer K Mulligan
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Int Forum Allergy Rhinol 1:268-74. 2011
    ..Therefore, in these studies we investigated the ability of Aspergillus fumigatus exposed HSNECs to regulate DC antigen uptake, maturation, and direction of T-cell T helper 1 (Th1)/Th2 skewing...
  13. doi request reprint Adenoid ciliostimulation in children with chronic otitis media
    Steven M Andreoli
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Ave, MSC 550, Charleston, SC 29403, USA
    Otolaryngol Head Neck Surg 148:135-9. 2013
    ..This study intends to determine the relationship between chronic otitis media and dynamic ciliary beat frequency in children undergoing adenoidectomy...
  14. ncbi request reprint Vitamin D3 deficiency increases sinus mucosa dendritic cells in pediatric chronic rhinosinusitis with nasal polyps
    Jennifer K Mulligan
    Research Service, Ralph H Johnson VA Medical Center, Charleston, South Carolina 29425, USA
    Otolaryngol Head Neck Surg 147:773-81. 2012
    ....
  15. doi request reprint Cytokine correlation between sinus tissue and nasal secretions among chronic rhinosinusitis and controls
    Samuel L Oyer
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina
    Laryngoscope 123:E72-8. 2013
    ..Compare cytokine levels in sinus tissue to sinus secretions from controls and chronic rhinosinusitis patients...
  16. doi request reprint Factors contributing to failure in endoscopic skull base defect repair
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol Allergy 23:185-91. 2009
    ..Endoscopic repair of skull base (SB) defects is successful in over 90% of cases. Certain factors may contribute to failure of SB repair techniques or need for secondary repair...
  17. doi request reprint Medical therapy vs surgery for chronic rhinosinusitis: a prospective, multi-institutional study
    Timothy L Smith
    Division of Rhinology and Sinus Surgery, Oregon Sinus Center, Department of Otolaryngology Head and Neck Surgery, Oregon Health and Science University, Portland, OR, USA
    Int Forum Allergy Rhinol 1:235-41. 2011
    ..This study evaluates outcomes in patients who failed initial medical management and elect a subsequent treatment option, either continued medical management or endoscopic sinus surgery (ESS) coupled with continued medical management...
  18. ncbi request reprint Innate and adaptive mediators in cystic fibrosis and allergic fungal rhinosinusitis
    Margaret L Skinner
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 21:538-41. 2007
    ..The purpose of this study is to show and quantify the presence of SP A, SP D, tumor necrosis factor (TNF) alpha, (a Th1 marker), and eotaxin (a Th2 marker) in normal and diseased sinus mucosa...
  19. doi request reprint Intracranial complications before and after endoscopic skull base reconstruction
    Richard J Harvey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol 22:516-21. 2008
    ..The risk of developing complications, such as meningitis, in a skull base defect is unknown. Many ESBR are multilayered soft tissue repairs, and long-term prevention of ICCs is not well described...
  20. pmc Impact of synechiae after endoscopic sinus surgery on long-term outcomes in chronic rhinosinusitis
    Oswaldo A Henriquez
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, U S A
    Laryngoscope 123:2615-9. 2013
    ..The aim of this study was to evaluate the impact of synechiae formation on health-related quality of life (HRQoL) outcomes after ESS in patients with CRS...
  21. pmc Health state utility values in patients undergoing endoscopic sinus surgery
    Zachary M Soler
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Laryngoscope 121:2672-8. 2011
    ..A secondary goal was to assess the meaning of these values by comparing them with other chronic disease processes and currently available medical or surgical treatments...
  22. doi request reprint Primary human sinonasal epithelial cell culture model for topical drug delivery in patients with chronic rhinosinusitis with nasal polyposis
    Benjamin S Bleier
    Department of Otology and Laryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA, USA
    J Pharm Pharmacol 64:449-56. 2012
    ....
  23. doi request reprint Local production of antigen-specific IgE in different anatomic subsites of allergic fungal rhinosinusitis patients
    Chadwick N Ahn
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 141:97-103. 2009
    ..This study examines if there are anatomic variations in local IgE expression or if variations among fungal and nonfungal IgE exist...
  24. doi request reprint Socioeconomic factors in the diagnosis of allergic fungal rhinosinusitis
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 138:38-42. 2008
    ..2) To consider the potential impact of epidemiological differences on AFRS disease course...
  25. doi request reprint Combined image guidance and intraoperative computed tomography in facilitating endoscopic orientation within and around the paranasal sinuses
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 22:635-41. 2008
    ....
  26. doi request reprint Radiologic staging system for allergic fungal rhinosinusitis (AFRS)
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, GA, USA
    Otolaryngol Head Neck Surg 140:735-40. 2009
    ..1) Develop an objective method for quantifying radiologic bone erosion in allergic fungal rhinosinusitis (AFRS); and 2) assess the utility of the new CT scan staging system in differentiating AFRS patient groups...
  27. ncbi request reprint A systematic review and meta-analysis of asthma outcomes following endoscopic sinus surgery for chronic rhinosinusitis
    Rishi Vashishta
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC
    Int Forum Allergy Rhinol 3:788-94. 2013
    ..It is unclear if similar benefits exist when the upper airway is treated surgically. This study presents a systematic review and meta-analysis to assess the effects of endoscopic sinus surgery (ESS) on asthma outcomes...
  28. doi request reprint Characterization of B-cell subpopulations in patients with chronic rhinosinusitis
    Alkis J Psaltis
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Int Forum Allergy Rhinol 3:621-9. 2013
    ..The purpose of this study was to subcharacterize the B cell response in the sinus mucosa of control and CRS patients...
  29. doi request reprint Systemic monocyte-derived dendritic cells and associated Th2 skewing in chronic rhinosinusitis
    Brendan P O'Connell
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Otolaryngol Head Neck Surg 150:312-20. 2014
    ....
  30. doi request reprint Reactive oxygen species in chronic rhinosinusitis and secondhand smoke exposure
    M Taylor Fordham
    Department of Otolaryngology, Medical University of South Carolina, Charleston, South Carolina, USA
    Otolaryngol Head Neck Surg 149:633-8. 2013
    ....
  31. doi request reprint Changing trends in sinus and septal surgery, 2007 to 2009
    Alkis J Psaltis
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Int Forum Allergy Rhinol 2:357-61. 2012
    ..The aim of this study was to identify recent changes in the performance and coding of certain endoscopic sinus surgical procedures (ESS) in the hope of generating further discussion and research in this area...
  32. doi request reprint Murine complement deficiency ameliorates acute cigarette smoke-induced nasal damage
    Kara S Davis
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 143:152-8. 2010
    ..The mechanism(s) responsible for this activation is unclear. We investigated the effects of cigarette smoke on nasal mucosa in vitro and via a model of cigarette smoke exposure by using animals deficient in complement components...
  33. doi request reprint Randomized controlled trial of hyaluronic acid/carboxymethylcellulose dressing after endoscopic sinus surgery
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina Hospital, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 72:101-5. 2010
    ..To determine if a hyaluronic acid/carboxymethylcellulose (HA/CMC) sinus dressing reduces the rate of postoperative scarring...
  34. doi request reprint Antigen-specific IgE in sinus mucosa of allergic fungal rhinosinusitis patients
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol 22:451-6. 2008
    ..In allergic fungal rhinosinusitis (AFRS), specific IgE has been established in nasal lavage fluid and eosinophilic mucin. In this study, local production of antigen-specific IgE within sinus mucosa of AFRS patients was evaluated...
  35. doi request reprint Temporal bone pneumatization and its relationship to paranasal sinus development in cystic fibrosis
    Clarice M Seifert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Rhinology 48:233-8. 2010
    ..It is often assumed that mucosal disease of the paranasal sinuses will negatively influence development and pneumotization of the paranasal sinuses and temporal bone system...
  36. ncbi request reprint Spontaneous cerebrospinal fluid leaks: a variant of benign intracranial hypertension
    Rodney J Schlosser
    Dept of Otolaryngology Head and Neck Surgery, 135 Rutledge Ave, Suite 1130, PO Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Ann Otol Rhinol Laryngol 115:495-500. 2006
    ..In this study we examined the clinical diagnosis of benign intracranial hypertension (BIH) in this population using the modified Dandy criteria...
  37. ncbi request reprint Presence of surfactant lamellar bodies in normal and diseased sinus mucosa
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 67:199-202. 2005
    ..In addition to the lung, lamellar bodies have been identified in many other cell types throughout the human body. However, no prior studies have identified lamellar bodies in human sinus mucosa...
  38. ncbi request reprint Endoscopic repair of skull base defects presenting with pneumocephalus
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Otolaryngol Head Neck Surg 38:509-16. 2009
    ..Such defects require treatment to avoid sequelae. The study objective was to evaluate success in endoscopic closure of SB defects associated with pneumocephalus...
  39. ncbi request reprint Evolutions in the management of congenital intranasal skull base defects
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Arch Otolaryngol Head Neck Surg 130:1283-8. 2004
    ..Congenital skull base defects have traditionally been treated via an intracranial approach. Recent advances in endoscopic management have made minimally invasive extracranial approaches feasible, with less morbidity...
  40. doi request reprint Post-FESS middle meatal dressings: avoiding the inevitable?
    Zachary M Soler
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston
    JAMA Otolaryngol Head Neck Surg 139:1351-4. 2013
    ..Use of dressings in the middle meatus after functional endoscopic sinus surgery (FESS) improves clinically meaningful outcomes in patients with chronic rhinosinusitis (CRS)...
  41. doi request reprint The role of fungi in diseases of the nose and sinuses
    Zachary M Soler
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol Allergy 26:351-8. 2012
    ..There has been much debate regarding the precise role fungal species play in sinonasal disease and optimal treatment strategies...
  42. doi request reprint Modified endoscopic medial maxillectomy for recalcitrant chronic maxillary sinusitis
    Eric W Wang
    Department of Otorhinolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
    Int Forum Allergy Rhinol 1:493-7. 2011
    ..We evaluate the efficacy of MEMM for chronic maxillary sinusitis and attempt to identify factors that predispose patients for failure...
  43. doi request reprint Localized immunoglobulin E expression in allergic rhinitis and nasal polyposis
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia, USA
    Curr Opin Otolaryngol Head Neck Surg 17:216-22. 2009
    ..Discussions of local IgE expression in allergic and nonallergic rhinitis, atopic and nonatopic sinonasal polyposis, and allergic fungal rhinosinusitis are included...
  44. ncbi request reprint Surfactant protein A and D in human sinus mucosa: a preliminary report
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    ORL J Otorhinolaryngol Relat Spec 69:57-60. 2007
    ..The objective of this study was to test our hypothesis that SP-A and SP-D are present in the human sinus...
  45. ncbi request reprint Elevated intracranial pressures in spontaneous cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 17:191-5. 2003
    ..We present clinical and radiographic evidence that indicates elevated ICP in this group. In addition, we review the pathophysiology and unique management issues in caring for patients with spontaneous CSF leak...
  46. doi request reprint The utility of cadaver dissection in endoscopic sinus surgery training courses
    Jodi D Zuckerman
    Department of Otolaryngology Head and Neck Surgery, Emory University, Atlanta, Georgia 30322, USA
    Am J Rhinol Allergy 23:218-24. 2009
    ....
  47. ncbi request reprint Incidence of skull base and orbital erosion in allergic fungal rhinosinusitis (AFRS) and non-AFRS
    Mark D Ghegan
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Otolaryngol Head Neck Surg 134:592-5. 2006
    ..To compare the incidence of bony erosion associated with allergic fungal rhinosinusitis (AFRS) with the incidence of bony erosion seen in other types of inflammatory sinusitis...
  48. doi request reprint Contamination of sinus irrigation devices: a review of the evidence and clinical relevance
    Alkis J Psaltis
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425 5500, USA
    Am J Rhinol Allergy 26:201-3. 2012
    ..Although high-level studies have consistently shown the benefit of saline in symptom improvement of CRS patients, to date, only lower-level evidence exists advocating a benefit of other topical medications...
  49. ncbi request reprint Chronic rhinosinusitis in congenital craniofacial malformations
    Bradford A Woodworth
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Int J Pediatr Otorhinolaryngol 70:247-52. 2006
    ..To review developmental abnormalities and iatrogenic alterations in sinus anatomy that may predispose patients with congenital craniofacial malformations to chronic rhinosinusitis...
  50. doi request reprint Cost-effective airway cultures in the cystic fibrosis patient
    Mark D Ghegan
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina MUSC, Charleston, SC 29425, USA
    Am J Otolaryngol 30:150-2. 2009
    ..Cystic fibrosis (CF) patients have a high incidence of multidrug-resistant infections, rendering CF patients a treatment challenge...
  51. ncbi request reprint Immunolocalization of surfactant protein A and D in sinonasal mucosa
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South, Charleston 29425, USA
    Am J Rhinol 20:461-5. 2006
    ..Our prior studies are the first to identify the presence of these proteins in the human sinonasal cavity. The objective of this study was to immunolocalize SP-A and SP-D in human sinonasal tissue...
  52. doi request reprint Spontaneous CSF Leaks
    Eric W Wang
    Division of Rhinology, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29403, USA
    Otolaryngol Clin North Am 44:845-56, vii. 2011
    ..Endoscopic repair of the CSF fistula is the gold standard treatment for this condition, but emerging evidence supports the reduction of CSF pressure as an important adjuvant treatment in this patient population...
  53. ncbi request reprint Socioeconomic factors in allergic fungal rhinosinusitis with bone erosion
    Mark D Ghegan
    Departmalest of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol 21:560-3. 2007
    ..The aim of this study was to evaluate the contribution of race, ethnicity, and various socioeconomic factors to the advanced presentation of AFRS with orbital and skull base bone erosion...
  54. ncbi request reprint Surfactant and its role in chronic sinusitis
    Rodney J Schlosser
    Division of Rhinology and Sinus Surgery, Dept of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Ave, Suite 1130, PO Box 250550, Charleston, SC 29425, USA
    Ann Otol Rhinol Laryngol Suppl 196:40-4. 2006
    ..These findings may lead to potential therapeutic options for difficult-to-treat sinus disease in the future...
  55. doi request reprint Spontaneous cerebrospinal fluid leak and management of intracranial pressure
    Zachary M Soler
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA
    Adv Otorhinolaryngol 74:92-103. 2013
    ..Specific attention will be given to endoscopic methods of repair and the importance of idiopathic intracranial hypertension as a possible comorbidity and contributing factor...
  56. doi request reprint Effects of endoscopic sinus surgery and delivery device on cadaver sinus irrigation
    Richard J Harvey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Otolaryngol Head Neck Surg 139:137-42. 2008
    ..Assess paranasal sinus distribution of topical solutions following endoscopic sinus surgery (ESS) using various delivery devices...
  57. ncbi request reprint Alterations in eotaxin, monocyte chemoattractant protein-4, interleukin-5, and interleukin-13 after systemic steroid treatment for nasal polyps
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Otolaryngol Head Neck Surg 131:585-9. 2004
    ..To determine alterations in Th2 chemokines eotaxin and monocyte chemoattractant protein-4 (MCP-4), and cytokines interleukin-5 (IL-5) and interleukin-13 (IL-13), in nasal polyps (NP) after steroid treatment...
  58. ncbi request reprint The delta F508 mutation in cystic fibrosis and impact on sinus development
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 21:122-7. 2007
    ..The purpose of this study was to determine whether the homozygous delta F508 mutation is associated with an increased incidence of sinus hypoplasia when compared with other mutations...
  59. ncbi request reprint Orbital volumetric analysis of allergic fungal sinusitis patients with proptosis before and after endoscopic sinus surgery
    Angela Chu Stonebraker
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Rhinol 19:302-6. 2005
    ..The aim of this study was to examine the changes of orbital volumes in allergic fungal sinusitis (AFS) patients with proptosis who undergo endoscopic sinus surgery...
  60. ncbi request reprint Modified endoscopic medial maxillectomy for chronic maxillary sinusitis
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, 135 Rutledge Avenue, Suite 1130, P O Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Rhinol 20:317-9. 2006
    ..However, few reports discuss the efficacy of MEMM for treatment of inflammatory disease of the maxillary sinus. We evaluate the efficacy of MEMM in treating chronic maxillary sinusitis...
  61. ncbi request reprint Endoscopic management of benign sinonasal tumors: a decade of experience
    Scott D London
    Department of Otolaryngology, Head and Neck Surgery, University of Virginia Health Sciences Center, Charlottesville 22908 0713, USA
    Am J Rhinol 16:221-7. 2002
    ..A variety of benign tumors present in the nasal and paranasal sinuses...
  62. ncbi request reprint Skull base erosion by sphenoid fungus balls: diagnosis and endoscopic treatment
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, University of Virginia Health Sciences Center, Charlottesville, USA
    Am J Rhinol 16:161-4. 2002
    ..Fungus balls typically are innocuous lesions found in immunocompetent hosts. They are located most commonly in the maxillary sinus but may be life-threatening when found in the sphenoid sinus...
  63. ncbi request reprint Significance of empty sella in cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Otolaryngol Head Neck Surg 128:32-8. 2003
    ..We present our experience with CSF leaks of various causes, the prevalence of ESS in the spontaneous and nonspontaneous categories, and the potential pathophysiology and unique management issues of the spontaneous CSF leak group...
  64. doi request reprint A systematic review of the endoscopic repair of cerebrospinal fluid leaks
    Alkis J Psaltis
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Otolaryngol Head Neck Surg 147:196-203. 2012
    ..To provide an up-to-date review of the literature on the safety and efficacy of the endoscopic technique for cerebrospinal (CSF) leak repairs...
  65. ncbi request reprint Clinical improvement after escalation for sublingual immunotherapy (SLIT)
    Jamie Woody
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, College of Health Professions PA Program, 151 B Rutledge Avenue, MSC 962, Charleston, SC 29425, USA
    Ear Nose Throat J 90:E16-22. 2011
    ..05). Significant improvement is seen immediately post-escalation in SLIT patients. This improved QOL appears to be maintained, and perhaps even increases, during the maintenance phase, with decreased nasal steroid use...
  66. ncbi request reprint Immunolocalization of dendritic cells and pattern recognition receptors in chronic rhinosinusitis
    Andrew M Rampey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina and the Ralph H Johnson VA Medical Center, Charleston, South Carolina, USA
    Am J Rhinol 21:117-21. 2007
    ..TLR binding is known to activate DCs. Based on these observations, we sought to establish the presence, in sinonasal mucosa, of DC and the pattern recognition receptors (PRRs), CD14, TLR2, and TLR4...
  67. ncbi request reprint Management of paranasal sinus malignancy
    Terry A Day
    Head and Neck Tumor Program, Hollings Cancer Center, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
    Curr Treat Options Oncol 6:3-18. 2005
    ..However, additional clinical trials are necessary to systematically evaluate the locoregional control, organ-preservation strategies, and survival related to the variety of treatments currently available...
  68. ncbi request reprint Tornwaldt's cyst: incidence and a case report
    Marcus W Moody
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston 29425, USA
    Ear Nose Throat J 86:45-7, 52. 2007
    ..Tornwaldt's cyst should be remembered as an uncommon but potentially treatable cause of many symptoms seen in a typical otolaryngology practice...
  69. doi request reprint PET/CT in the assessment of previously treated skull base malignancies
    Richard J Harvey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Head Neck 32:76-84. 2010
    ..The diagnostic characteristics of positron emission tomography/CT (PET/CT) studies in those with suspected recurrent malignancy were assessed...
  70. doi request reprint Prevention and management of medial rectus injury
    Benjamin S Bleier
    Division of Rhinology, Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA
    Otolaryngol Clin North Am 43:801-7. 2010
    ..Despite optimal surgical and medical interventions, the prognosis is relatively poor and patients should be counseled that the primary goal of these interventions is to reestablish a binocular single visual field...
  71. ncbi request reprint Comparison of techniques for transsphenoidal pituitary surgery
    Jeffrey G Neal
    Departments of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 21:203-6. 2007
    ....
  72. doi request reprint Cigarette smoke inhibits dynamic ciliary beat frequency in pediatric adenoid explants
    Ling feng Wang
    Medical University of South Carolina, Department of Otolaryngology Head and Neck Surgery, Charleston, South Carolina 29403, USA
    Otolaryngol Head Neck Surg 146:659-63. 2012
    ..This study investigated the effects of ex vivo and in vitro smoke exposure on dynamic ciliary beat frequency (CBF) in pediatric adenoid explants...
  73. doi request reprint Cigarette smoke extract stimulates interleukin-8 production in human airway epithelium and is attenuated by superoxide dismutase in vitro
    Ryan M Mulligan
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol Allergy 23:e1-4. 2009
    ..Cigarette smoke exposure (CSE) results in extensive inflammation in the upper and lower airways. Reactive oxygen species, such as superoxide, have been shown to be potent mediators of this inflammation...
  74. ncbi request reprint Frontal sinus complications after frontal craniotomy
    Keith Meetze
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Laryngoscope 114:945-8. 2004
    ..To review frontal sinus complications following frontal craniotomy and to describe management strategies...
  75. ncbi request reprint Nasal cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology, Medical University of South Carolina, Charleston, USA
    J Otolaryngol 31:S28-37. 2002
    ....
  76. doi request reprint Quality of life outcomes with sublingual immunotherapy
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Otolaryngol 30:305-11. 2009
    ..The purpose of this study was to evaluate quality of life measures in a preliminary patient sample initiating SLIT at our institution...
  77. ncbi request reprint Endoscopic repair of a congenital intranasal encephalocele in a 23 months old infant
    Brad Woodworth
    Department of Otolaryngology Head and Neck Surgery, 135 Rutledge Ave, Suite 1130, P O Box 250550, Medical University of South Carolina, Charleston, SC 29425, USA
    Int J Pediatr Otorhinolaryngol 69:1007-9. 2005
    ..Continued advances in technology and skill will increase the feasibility of transnasal endoscopic skull base surgery in younger patients...
  78. doi request reprint Assessment of palatability of two sublingual diluents in allergic patients: a prospective pilot study
    Shaun A Nguyen
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Am J Rhinol Allergy 25:342-5. 2011
    ..This study assessed the palatability and compared the flavor and taste preferences of two sublingual diluents in allergic adult patients...
  79. ncbi request reprint Rapid method for beta2-transferrin in cerebrospinal fluid leakage using an automated immunofixation electrophoresis system
    Christine Papadea
    Division of Laboratory Medicine, Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425, USA
    Clin Chem 51:464-70. 2005
    ....
  80. ncbi request reprint Evaluation of spontaneous nasal cerebrospinal fluid leaks
    Sarah K Wise
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Curr Opin Otolaryngol Head Neck Surg 15:28-34. 2007
    ..In addition, this patient group requires special perioperative and intraoperative considerations for suitable management...
  81. ncbi request reprint Three-dimensional computed tomography of congenital nasal anomalies
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC, USA
    Int J Pediatr Otorhinolaryngol 65:125-31. 2002
    ....
  82. ncbi request reprint Spontaneous nasal cerebrospinal fluid leaks and empty sella syndrome: a clinical association
    Rodney J Schlosser
    Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Am J Rhinol 17:91-6. 2003
    ..The objective of this study was to examine the association between spontaneous encephaloceles/CSF leaks and empty sella syndrome because of their similar clinical features and potential common pathophysiology...
  83. ncbi request reprint Surfactant protein B detection and gene expression in chronic rhinosinusitis
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, Pennsylvania 19104, USA
    Laryngoscope 117:1296-301. 2007
    ..Our objective was to detect the presence of SP-B, measure alterations in several forms of chronic rhinosinusitis (CRS), and localize cellular protein expression...
  84. ncbi request reprint Management of multiple spontaneous nasal meningoencephaloceles
    Rodney J Schlosser
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia 19104, USA
    Laryngoscope 112:980-5. 2002
    ..We present our experience with this unusual condition and discuss its pathophysiology and unique management issues...
  85. ncbi request reprint Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
    Otolaryngol Head Neck Surg 137:34-8. 2007
    ..To measure alterations in SPA1, A2, and D gene expression in various forms of inflammatory chronic rhinosinusitis (CRS)...
  86. ncbi request reprint Radiographic signs of elevated intracranial pressure in idiopathic cerebrospinal fluid leaks: a possible presentation of idiopathic intracranial hypertension
    Ross I Silver
    Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Am J Rhinol 21:257-61. 2007
    ..We sought to identify radiographic manifestations suggestive of elevated ICP in 14 patients with idiopathic CSF leaks who clinically and epidemiologically resembled patients with IIH...
  87. doi request reprint Spontaneous CSF leaks: a paradigm for definitive repair and management of intracranial hypertension
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104 4206, USA
    Otolaryngol Head Neck Surg 138:715-20. 2008
    ..To report our outcomes with the repair of spontaneous cerebrospinal fluid (CSF) leaks and to demonstrate how management of underlying intracranial hypertension improves outcomes...
  88. ncbi request reprint What's new in skull base medicine and surgery? Skull Base Committee Report
    Ritvik P Mehta
    American Academy of Otolaryngology Head and Neck Surgery, Alexandria, Virginia, USA
    Otolaryngol Head Neck Surg 135:620-30. 2006
  89. ncbi request reprint Endoscopic and endoscope-assisted resections of inverted sinonasal papillomas
    Stephen G Wolfe
    Department of Otohinolaryngology Head and Neck Surgery, University of Pennsylvania, Philadelphia, PA, USA
    Otolaryngol Head Neck Surg 131:174-9. 2004
    ..To evaluate the success of endoscopic and endoscope-assisted resection of inverted sinonasal papillomas and to assess the indications for adjunctive external procedures...
  90. ncbi request reprint Comparison of laser versus surface-touch registration for image-guided sinus surgery
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina Hospital, Charleston 29425, USA
    Am J Rhinol 19:623-6. 2005
    ..The laser registration technique has been used previously; however, a less expensive surface-touch registration technique recently has been developed. We compared the accuracy and speed of laser and surface-touch registration techniques...
  91. ncbi request reprint The endoscopic modified Lothrop: long-term follow-up on 44 patients
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, University of Virginia Health Sciences Center, Charlottesville 22908 0713, USA
    Am J Rhinol 16:103-8. 2002
    ..In an attempt to preserve the frontal sinus, we have been performing the endoscopic modified Lothrop orfrontal drill-out...