Venkatesh Sampath

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. doi request reprint A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    Pediatr Pulmonol 47:460-8. 2012
  2. pmc Attenuation of lipopolysaccharide-induced oxidative stress and apoptosis in fetal pulmonary artery endothelial cells by hypoxia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA
    Free Radic Biol Med 46:663-71. 2009
  3. doi request reprint The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    J Surg Res 169:e51-7. 2011
  4. pmc LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
    Heather Menden
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Physiol Lung Cell Mol Physiol 304:L445-55. 2013
  5. doi request reprint Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation
    Jeremy T Leverence
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States
    Chem Biol Interact 189:72-81. 2011
  6. doi request reprint Antioxidant response genes sequence variants and BPD susceptibility in VLBW infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin
    Pediatr Res 77:477-83. 2015

Collaborators

Detail Information

Publications6

  1. doi request reprint A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    Pediatr Pulmonol 47:460-8. 2012
    ..Our data support the hypothesis that aberrant pathogen recognition in premature infants arising from TLR pathway genetic variation can contribute to BPD pathogenesis...
  2. pmc Attenuation of lipopolysaccharide-induced oxidative stress and apoptosis in fetal pulmonary artery endothelial cells by hypoxia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA
    Free Radic Biol Med 46:663-71. 2009
    ..We conclude that ambient oxygen concentration modulates the severity of LPS-mediated injury in FPAEC by regulating superoxide levels produced in response to LPS...
  3. doi request reprint The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    J Surg Res 169:e51-7. 2011
    ..We hypothesized that altered intestinal immune responses arising from sequence variation in the toll-like receptor (TLR) pathway genes contribute to NEC susceptibility...
  4. pmc LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
    Heather Menden
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Physiol Lung Cell Mol Physiol 304:L445-55. 2013
    ..Inhibition of vascular Nox may potentially limit lung injury and alveolar remodeling caused by infections in BPD...
  5. doi request reprint Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation
    Jeremy T Leverence
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States
    Chem Biol Interact 189:72-81. 2011
    ..We conclude that PKCζ-mediated p47phox activation regulates LPS-dependent cytokine expression in AEC. Selective inhibition of PKCζ or p47phox might attenuate LPS-mediated inflammation and alveolar remodeling in BPD...
  6. doi request reprint Antioxidant response genes sequence variants and BPD susceptibility in VLBW infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin
    Pediatr Res 77:477-83. 2015
    ..We hypothesized that ARE genetic variants will modulate susceptibility or severity of BPD in very-low-birth-weight (VLBW) infants...