Venkatesh Sampath

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. doi request reprint A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    Pediatr Pulmonol 47:460-8. 2012
  2. pmc Attenuation of lipopolysaccharide-induced oxidative stress and apoptosis in fetal pulmonary artery endothelial cells by hypoxia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA
    Free Radic Biol Med 46:663-71. 2009
  3. doi request reprint The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    J Surg Res 169:e51-7. 2011
  4. pmc LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
    Heather Menden
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Physiol Lung Cell Mol Physiol 304:L445-55. 2013
  5. doi request reprint Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation
    Jeremy T Leverence
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States
    Chem Biol Interact 189:72-81. 2011

Collaborators

Detail Information

Publications5

  1. doi request reprint A TLR5 (g.1174C > T) variant that encodes a stop codon (R392X) is associated with bronchopulmonary dysplasia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    Pediatr Pulmonol 47:460-8. 2012
    ..Our data support the hypothesis that aberrant pathogen recognition in premature infants arising from TLR pathway genetic variation can contribute to BPD pathogenesis...
  2. pmc Attenuation of lipopolysaccharide-induced oxidative stress and apoptosis in fetal pulmonary artery endothelial cells by hypoxia
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, USA
    Free Radic Biol Med 46:663-71. 2009
    ..We conclude that ambient oxygen concentration modulates the severity of LPS-mediated injury in FPAEC by regulating superoxide levels produced in response to LPS...
  3. doi request reprint The NFKB1 (g.-24519delATTG) variant is associated with necrotizing enterocolitis (NEC) in premature infants
    Venkatesh Sampath
    Department of Pediatrics, Medical College of Wisconsin, and Children s Research Institute, Children s Hospital and Health Systems, Milwaukee, Wisconsin, USA
    J Surg Res 169:e51-7. 2011
    ..We hypothesized that altered intestinal immune responses arising from sequence variation in the toll-like receptor (TLR) pathway genes contribute to NEC susceptibility...
  4. pmc LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-β phosphorylation
    Heather Menden
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
    Am J Physiol Lung Cell Mol Physiol 304:L445-55. 2013
    ..Inhibition of vascular Nox may potentially limit lung injury and alveolar remodeling caused by infections in BPD...
  5. doi request reprint Lipopolysaccharide-induced cytokine expression in alveolar epithelial cells: role of PKCζ-mediated p47phox phosphorylation
    Jeremy T Leverence
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, United States
    Chem Biol Interact 189:72-81. 2011
    ..We conclude that PKCζ-mediated p47phox activation regulates LPS-dependent cytokine expression in AEC. Selective inhibition of PKCζ or p47phox might attenuate LPS-mediated inflammation and alveolar remodeling in BPD...