Jong In Park
Affiliation: Medical College of Wisconsin
- Mitochondria-Targeted Nitroxide, Mito-CP, Suppresses Medullary Thyroid Carcinoma Cell Survival In Vitro and In VivoDmytro Starenki
PhD, Department of Biochemistry, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226
J Clin Endocrinol Metab 98:1529-40. 2013..Conclusion: Our results suggest that Mito-CP can effectively suppress MTC cell growth/survival via a mechanism distinct from vandetanib effects. Mitochondrial targeting may be a potential strategy for MTC therapy...
- Mechanisms of MEK/ERK growth arrest signalingJong In Park; Fiscal Year: 2010..Exploration of the possibility that these cancer types can be effectively suppressed by modulating the pathway via mortalin into the direction of growth arrest may allow development of new therapeutic strategies to control them. ..