JANARDAN PANDEY

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi request reprint TNF-alpha, IL1-beta, and immunoglobulin (GM and KM) gene polymorphisms in sarcoidosis
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston 29425 2230, USA
    Hum Immunol 63:485-91. 2002
  2. ncbi request reprint Immunoglobulin KM and GM gene polymorphisms modify the clinical presentation of primary Sjögren's syndrome
    Marja Pertovaara
    Department of Internal Medicine and the Centre for Laboratory Medicine, Tampere University Hospital, Tampere, Finland
    J Rheumatol 31:2175-80. 2004
  3. ncbi request reprint Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype
    Christine G Parks
    National Institute of Environmental Health Sciences, Durham, North Carolina, USA
    Arthritis Rheum 52:1148-59. 2005
  4. ncbi request reprint Speed of tooth movement is related to stress and IL-1 gene polymorphisms
    Laura R Iwasaki
    Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln 68583 0755, USA
    Am J Orthod Dentofacial Orthop 130:698.e1-9. 2006
  5. ncbi request reprint Immunoglobulin GM and FcγRIIIa genotypes influence cytotoxicity of neuroblastoma cells
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA Electronic address
    J Neuroimmunol 270:95-7. 2014
  6. doi request reprint IGKC and FcγR genotypes and humoral immunity to HER2 in breast cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA Electronic address
    Immunobiology 219:113-7. 2014
  7. ncbi request reprint Suggestive evidence that Fc variants of IgG2 and FcγRIIa loci interact to contribute to the risk of prostate cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA Electronic address
    Hum Immunol 74:1656-8. 2013
  8. doi request reprint IgG and FcγR genotypes and humoral immunity to mucin 1 in prostate cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Hum Immunol 74:1030-3. 2013
  9. pmc Immunoglobulin genes and the acquisition of HIV infection in a randomized trial of recombinant adenovirus HIV vaccine
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA
    Virology 441:70-4. 2013
  10. pmc Racially restricted contribution of immunoglobulin Fcγ and Fcγ receptor genotypes to humoral immunity to human epidermal growth factor receptor 2 in breast cancer
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Clin Exp Immunol 171:273-7. 2013

Research Grants

Collaborators

Detail Information

Publications57

  1. ncbi request reprint TNF-alpha, IL1-beta, and immunoglobulin (GM and KM) gene polymorphisms in sarcoidosis
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston 29425 2230, USA
    Hum Immunol 63:485-91. 2002
    ..5% versus 13.0%, p = 0.01; odds ratio = 2.56). As KM genes have been reported to be associated with immune responsiveness to several pathogens, these results may be relevant to the etiology of sarcoidosis...
  2. ncbi request reprint Immunoglobulin KM and GM gene polymorphisms modify the clinical presentation of primary Sjögren's syndrome
    Marja Pertovaara
    Department of Internal Medicine and the Centre for Laboratory Medicine, Tampere University Hospital, Tampere, Finland
    J Rheumatol 31:2175-80. 2004
    ..To investigate whether polymorphism of immunoglobulin (Ig) genes affects susceptibility to or severity of primary Sjogren's syndrome (pSS)...
  3. ncbi request reprint Association of Epstein-Barr virus with systemic lupus erythematosus: effect modification by race, age, and cytotoxic T lymphocyte-associated antigen 4 genotype
    Christine G Parks
    National Institute of Environmental Health Sciences, Durham, North Carolina, USA
    Arthritis Rheum 52:1148-59. 2005
    ..This study examined the seroprevalence of EBV in a population-based study of SLE patients from the southeastern United States, and potential interactions with CTLA-4 polymorphisms were assessed...
  4. ncbi request reprint Speed of tooth movement is related to stress and IL-1 gene polymorphisms
    Laura R Iwasaki
    Department of Oral Biology, College of Dentistry, University of Nebraska Medical Center, Lincoln 68583 0755, USA
    Am J Orthod Dentofacial Orthop 130:698.e1-9. 2006
    ....
  5. ncbi request reprint Immunoglobulin GM and FcγRIIIa genotypes influence cytotoxicity of neuroblastoma cells
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA Electronic address
    J Neuroimmunol 270:95-7. 2014
    ..21%; p=0.00004). These and other findings presented here could lead to a more effective immunotherapy of neuroblastoma...
  6. doi request reprint IGKC and FcγR genotypes and humoral immunity to HER2 in breast cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA Electronic address
    Immunobiology 219:113-7. 2014
    ..This is the first report implicating KM alleles in the immunobiology of breast cancer. ..
  7. ncbi request reprint Suggestive evidence that Fc variants of IgG2 and FcγRIIa loci interact to contribute to the risk of prostate cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA Electronic address
    Hum Immunol 74:1656-8. 2013
    ..To our knowledge, this is the first report implicating GM and FcγR loci as risk/protective factors for prostate cancer. Additional, independent, studies are warranted to confirm and extend these findings...
  8. doi request reprint IgG and FcγR genotypes and humoral immunity to mucin 1 in prostate cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Hum Immunol 74:1030-3. 2013
    ..044). These results, the first to implicate FcγRIIIa and KM loci in humoral immunity to MUC1 in prostate cancer, might be relevant to MUC1-based immunotherapy of this malignancy. ..
  9. pmc Immunoglobulin genes and the acquisition of HIV infection in a randomized trial of recombinant adenovirus HIV vaccine
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA
    Virology 441:70-4. 2013
    ..0016; FDR=0.0960), and GM23+/-FcγRIIIa (interaction p=0.0060; FDR=0.1200). These results suggest the involvement of GM, KM, and FcγRIIIa loci in the acquisition of HIV infection. Additional studies are warranted...
  10. pmc Racially restricted contribution of immunoglobulin Fcγ and Fcγ receptor genotypes to humoral immunity to human epidermal growth factor receptor 2 in breast cancer
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Clin Exp Immunol 171:273-7. 2013
    ..No significant associations were found in other study groups. These racially restricted contributions of GM and FcγR genotypes to humoral immunity to HER2 have potential implications for immunotherapy of breast cancer...
  11. pmc The forgotten tale of immunoglobulin allotypes in cancer risk and treatment
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA
    Exp Hematol Oncol 2:6. 2013
    ....
  12. doi request reprint A genetic variant of FcγRIIIa is strongly associatedwith humoral immunity to cyclin B1 in African American patients with prostate cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Immunogenetics 65:91-6. 2013
    ..0007). Since immunity to cyclin B1 has been shown to play a protective role, these results may, at least in part, explain the disproportionately higher rate of mortality in AA patients with prostate cancer...
  13. doi request reprint Genetic markers of immunoglobulin G and susceptibility to breast cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Hum Immunol 73:1155-8. 2012
    ..Since this allele modulates an immune evasion strategy of cytomegalovirus, the results also shed light on the possible mechanism underlying the reported involvement of this virus in the etiology of breast cancer...
  14. pmc Antigen-specific influence of GM/KM allotypes on IgG isotypes and association of GM allotypes with susceptibility to Plasmodium falciparum malaria
    Hayder A Giha
    Department of Biochemistry, Faculty of Medicine and Medical Sciences, Arabian Gulf University AGU, PO Box 26671, Manama, Kingdom of Bahrain
    Malar J 8:306. 2009
    ..Plasmodium falciparum malaria is a complex disease in which genetic and environmental factors influence susceptibility. IgG isotypes are in part genetically controlled, and GM/KM allotypes are believed to be involved in this control...
  15. pmc Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA
    Hum Immunol 69:158-64. 2008
    ....
  16. ncbi request reprint Immunoglobulin KM allotypes are associated with the prevalence of autoantibodies to GD1a ganglioside, but not with susceptibility to the disease, in Japanese patients with Guillain-Barré syndrome
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Neurogenetics 6:225-8. 2005
    ..These results suggest that KM allotypes are not risk factors for developing GBS, but contribute significantly to the generation of autoimmune responses to GD1a ganglioside in patients with this disease...
  17. doi request reprint Genetic and viral etiology of glioblastoma--a unifying hypothesis
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425 2230, USA
    Cancer Epidemiol Biomarkers Prev 20:1061-3. 2011
    ....
  18. doi request reprint Immunoglobulin GM genes as functional risk and protective factors for the development of Alzheimer's disease
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    J Alzheimers Dis 17:753-6. 2009
    ..Results from genome-wide association and linkage studies in support of this hypothesis, testable predictions, and possible therapeutic implications are discussed...
  19. doi request reprint Genetic variation at immunoglobulin kappa locus is associated with hepatitis C-treatment-induced viral clearance in African Americans
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
    Hum Immunol 72:667-70. 2011
    ..12-5.60). Consistent with this finding, the HCV RNA level in KM1 noncarriers was significantly (p = 0.013) lower than in carriers of this allele. Thus, the KM3 allele may be a marker for higher SVR in African Americans...
  20. pmc Immunoglobulin GM 3 23 5,13,14 phenotype is strongly associated with IgG1 antibody responses to Plasmodium vivax vaccine candidate antigens PvMSP1-19 and PvAMA-1
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Malar J 9:229. 2010
    ....
  21. pmc Genetic markers of IgG influence the outcome of infection with hepatitis C virus
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    J Infect Dis 198:1334-6. 2008
    ..50; P= .01) in subjects who were carriers of the GM3 allele than in those who were noncarriers. These results show that particular GM alleles may be important determinants of the outcome of HCV infection...
  22. doi request reprint A genetic variant of immunoglobulin gamma2 is strongly associated with immunity to mucin 1 in patients with breast cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Cancer Immunol Immunother 58:2025-9. 2009
    ..003). These results could potentially divide the population into high or low responders to MUC1, which has important implications for MUC1-based immunotherapeutic interventions in breast cancer...
  23. pmc Interactive effects of immunoglobulin gamma and human leucocyte antigen genotypes on clearance and persistence of infection with hepatitis C virus
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Clin Exp Immunol 150:518-22. 2007
    ..80). These results show, for the first time, interactive effects of GM and HLA genotypes in the outcome of HCV infection...
  24. ncbi request reprint Significant differences in GM allotype frequencies between two sympatric tribes with markedly differential susceptibility to malaria
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Parasite Immunol 29:267-9. 2007
    ..03). These data suggest that GM allotypes may contribute to the genetic aetiology of malaria...
  25. ncbi request reprint Immunoglobulin GM and KM allotypes and vaccine immunity
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Vaccine 19:613-7. 2000
    ....
  26. ncbi request reprint Immunoglobulin GM and KM allotypes in systemic lupus erythematosus
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Exp Clin Immunogenet 18:117-22. 2001
    ..In African-Americans, however, the pattern of associations with KM phenotypes differed from that in Caucasians, and the overall difference between patients and controls was not statistically significant...
  27. ncbi request reprint Anti-fibrillin-1 autoantibodies in systemic sclerosis are GM and KM allotype-restricted
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Exp Clin Immunogenet 18:123-9. 2001
    ..In this ethnic group, the GM1,17 5,13 phenotype was associated with the absence of IgM autoantibodies. This represents the first description of genetic control of autoimmunity to fibrillin-1 in scleroderma...
  28. pmc A profibrotic polymorphism (of TGFbeta1) in systemic sclerosis
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston 29425, USA
    Ann Rheum Dis 61:671-2. 2002
  29. pmc Genetic regulation of antibody responses to human epidermal growth factor receptor 2 in breast cancer
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
    Hum Immunol 71:1124-7. 2010
    ..These results show that GM allotypes are associated with humoral immunity to HER-2, a finding with potentially significant implications for immunotherapy of breast cancer...
  30. ncbi request reprint Immunoglobulin KM genes in Guillain-Barré syndrome
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425 2230, USA
    Neurogenetics 4:147-9. 2003
    ..3% vs. 26%, P=0.01, odds ratio=0.4). These results suggest that KM genes may be relevant to the etiology of Guillain-Barré syndrome...
  31. ncbi request reprint Epistatic effects of genes encoding immunoglobulin GM allotypes and interleukin-6 on the production of autoantibodies to 60- and 65-kDa heat-shock proteins
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Genes Immun 5:68-71. 2004
    ..038) antibody levels. Since these autoantibodies have been implicated in susceptibility to coronary heart disease and carotid atherosclerosis, the associations reported here might be relevant to the etiology of these diseases...
  32. pmc Epistatic effects of immunoglobulin GM and KM allotypes on outcome of infection with hepatitis C virus
    Janardan P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425 2230, USA
    J Virol 78:4561-5. 2004
    ..Further investigations involving candidate genes (GM, KM, HLA, and Fcgamma receptors) and cellular and humoral immune responses to HCV epitopes are needed to understand the mechanisms underlying these associations...
  33. ncbi request reprint GM allotypes and IgG subclass concentrations in blacks
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston 29425 2230, USA
    Exp Clin Immunogenet 13:126-30. 1996
    ..IgG2 levels were not associated with any of the GM phenotypes. To our knowledge, this represents the first report of an association between GM allotypes and IgG subclasses in blacks...
  34. ncbi request reprint Immunoglobulin GM genes and IgG antibodies to cytomegalovirus in patients with systemic sclerosis
    J P Pandey
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Clin Exp Rheumatol 22:S35-7. 2004
    ..To determine the role of GM and KM genes--genetic markers of immunoglobulin gamma and kappa chains, respectively--in humoral immunity to human cytomegalovirus (HCMV) in patients with systemic sclerosis (SSc; scleroderma)...
  35. doi request reprint Immunoglobulin allotypes influence antibody responses to mucin 1 in patients with gastric cancer
    Janardan P Pandey
    Department of Microbiology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Cancer Res 68:4442-6. 2008
    ..0081). Levels of MUC1 IgM antibodies were not associated with these genetic markers. These results show, for the first time, that GM and KM allotypes contribute to the interindividual differences in humoral immunity to MUC1...
  36. ncbi request reprint CTLA-4 gene polymorphisms in systemic lupus erythematosus: a highly significant association with a determinant in the promoter region
    Lori L Hudson
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425 2230, USA
    Hum Genet 111:452-5. 2002
    ..These results show that allelic variation at the -1722 site influences susceptibility to SLE. This is the first report to our knowledge implicating CTLA-4 genotypes at the -1722 locus in susceptibility to any disease...
  37. ncbi request reprint Ethnic differences in cytotoxic T lymphocyte associated antigen 4 genotype associations with systemic sclerosis
    Lori L Hudson
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425 2230, USA
    J Rheumatol 31:85-7. 2004
    ..To determine the role of cytotoxic T lymphocyte associated antigen 4 (CTLA-4) genetic polymorphisms in susceptibility to systemic sclerosis (SSc, scleroderma)...
  38. ncbi request reprint IgG antibodies to human cytomegalovirus late protein UL94 in patients with systemic sclerosis
    Aryan M Namboodiri
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Autoimmunity 37:241-4. 2004
    ..465 ng/ml, p = 0.02). These results show that increased levels of antibodies to the HCMV late protein UL94 are associated with SSc and they may be a marker for the severity of the disease...
  39. pmc Fc gamma receptor-like hepatitis C virus core protein binds differentially to IgG of discordant Fc (GM) genotypes
    Aryan M Namboodiri
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA
    Mol Immunol 44:3805-8. 2007
    ..0003). These results provide a mechanistic explanation for the involvement of GM allotypes in the outcome of HCV infection. These findings also shed light on the possible evolutionary selective mechanism that maintains GM polymorphism...
  40. pmc Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus
    Henda Bouali
    Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Rheumatol 34:2028-34. 2007
    ..We hypothesized that the G-463A MPO SNP is a risk factor for developing lupus nephritis (LN) due to its potential influence on the inflammatory response...
  41. ncbi request reprint TNF-alpha and -beta gene polymorphisms in multiple sclerosis: a highly significant role for determinants in the first intron of the TNF-beta gene
    Jose Americo M Fernandes Filho
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
    Autoimmunity 35:377-80. 2002
    ..0012) in MS patients as compared to controls. TNF-alpha genotypes were not associated with MS. These results suggest that the TNF-beta gene plays a significant role in the etiopathogenesis of MS...
  42. pmc Hepatitis C virus core protein discriminates between the two IgG2 allotypes
    Aryan M Namboodiri
    Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
    Viral Immunol 21:273-6. 2008
    ..These findings also contribute toward our understanding of the mechanisms that maintain strong linkage disequilibrium between particular GM alleles...
  43. ncbi request reprint Genetic polymorphisms in tumor necrosis factor (TNF)-alpha and TNF-beta in a population-based study of systemic lupus erythematosus: associations and interaction with the interleukin-1alpha-889 C/T polymorphism
    Christine G Parks
    National Institute of Environmental Health Sciences, Durham, NC, USA
    Hum Immunol 65:622-31. 2004
    ..0, p < 0.00001) for the combined "HLA-DR3, TNF-alpha -308A, IL-1alpha -889C/C" genotype. These findings provide evidence of cytokine gene epistasis in SLE susceptibility...
  44. ncbi request reprint Immunoglobulin GM and KM genotypes in hepatitis C virus infection
    Sasijit Vejbaesya
    Department of Transfusion Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Virol 73:384-6. 2004
    ..5% vs. 3.7%, P = 0.02) in patients than the respective frequencies in controls. These results suggest that GM genotypes make a significant contribution to the risk of acquiring HCV infection...
  45. ncbi request reprint Single nucleotide polymorphisms of the inflammatory cytokine genes in adults with chronic immune thrombocytopenic purpura
    Takashi Satoh
    Institute for Advanced Medical Research, Keio University School of Medicine, Tokyo, Japan
    Br J Haematol 124:796-801. 2004
    ..02 and P < 0.001, respectively). These findings suggest that the SNP located at TNF-beta (+252) contributes to susceptibility to chronic ITP by controlling the autoreactive B-cell responses to platelet membrane glycoproteins...
  46. ncbi request reprint HLA class II alleles in systemic sclerosis patients with anti-RNA polymerase I/III antibody: associations with subunit reactivities
    Masataka Kuwana
    Institute for Advanced Medical Research, Keio University School of Medicine, 35 Shinanomachi, Shinjuku ku, Tokyo 160 8582, Japan
    J Rheumatol 30:2392-7. 2003
    ..To examine HLA class II gene associations with anti-RNA polymerase (RNAP) I/III antibody responses in patients with systemic sclerosis (SSc)...
  47. pmc HLA-DRB1*1101: a significant risk factor for sarcoidosis in blacks and whites
    Milton D Rossman
    Pulmonary, Allergy and Critical Care Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 19104, USA
    Am J Hum Genet 73:720-35. 2003
    ..These studies confirm a genetic predisposition for sarcoidosis and present evidence for the allelic variation at the HLA-DRB1 locus as a major contributor...
  48. pmc Immunoglobulin GM and KM allotypes and prevalence of anti-LKM1 autoantibodies in patients with hepatitis C virus infection
    Paolo Muratori
    Department of Internal Medicine, Alma Mater Stadiorum University of Bologna, Italy
    J Virol 80:5097-9. 2006
    ..The heterozygous GM 1,3,17 23 5,13,21 phenotype was significantly associated with the prevalence of anti-LKM1 antibodies (odds ratio, 5.13; P=0.002), suggesting its involvement in this autoimmune phenomenon in HCV infection...
  49. ncbi request reprint Interaction of KIR genes and G1M immunoglobulin allotypes confer susceptibility to type 2 diabetes in Puerto Rican Americans
    Joaquin Zuniga
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA
    Hum Immunol 67:907-14. 2006
    ..Our findings are important for understanding the autoimmune or innate immune inflammatory-mediated mechanisms involved in the pathogenesis of T2D...
  50. pmc Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity
    April Bingham
    From Office of Clinical Research, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, Maryland 20892 1301, USA
    Medicine (Baltimore) 87:70-86. 2008
    ..Further study is warranted to investigate the pathogenesis of acquired LD in patients with DM...
  51. doi request reprint Genetic interactions of KIR and G1M immunoglobulin allotypes differ in obese from non-obese individuals with type 2 diabetes
    Viviana Romero
    Department of Cancer Immunology and AIDS, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Mol Immunol 45:3857-62. 2008
    ....
  52. ncbi request reprint Differences in idiopathic inflammatory myopathy phenotypes and genotypes between Mesoamerican Mestizos and North American Caucasians: ethnogeographic influences in the genetics and clinical expression of myositis
    Ejaz A Shamim
    Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland, USA
    Arthritis Rheum 46:1885-93. 2002
    ....
  53. ncbi request reprint Enzyme-linked immunosorbent assay for detection of anti-RNA polymerase III antibody: analytical accuracy and clinical associations in systemic sclerosis
    Masataka Kuwana
    Keio University School of Medicine, Tokyo, Japan
    Arthritis Rheum 52:2425-32. 2005
    ..This study was conducted to assess the analytical accuracy and clinical associations of the anti-RNAP III ELISA in patients with systemic sclerosis (SSc)...
  54. ncbi request reprint Genetic polymorphism of Fc
    Janardan P Pandey
    Science 311:1376-7; author reply 1376-7. 2006

Research Grants3

  1. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2006
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..
  2. Immunoglobulin Allotypes in Hepatitis C Virus Infection
    JANARDAN PANDEY; Fiscal Year: 2007
    ..Results of this investigation will advance our understanding of the role of host genetic factors in clearance and persistence of hepatitis C virus infection. ..