P S Pagel


Affiliation: Medical College of Wisconsin
Country: USA


  1. Pagel P, Schroeder A, De Vry D, Hudetz J. Aortic valve replacement reduces valvuloarterial impedance but does not affect systemic arterial compliance in elderly men with degenerative calcific trileaflet aortic valve stenosis. J Cardiothorac Vasc Anesth. 2014;28:1540-4 pubmed publisher
    ..The current results showed that AVR acutely reduced Zva, improved energy loss index, and decreased stroke work loss, but did not affect systemic arterial compliance in elderly men with degenerative calcific trileaflet AS. ..
  2. Pagel P, Freed J, Lien C. Gender Differences in Authorship in the Journal of Cardiothoracic and Vascular Anesthesia: A 28-Year Analysis of Publications Originating From the United States, 1990-2017. J Cardiothorac Vasc Anesth. 2019;33:593-599 pubmed publisher
    ..These findings are encouraging, but women continue to be underrepresented in corresponding and last author roles. ..
  3. Pagel P, Dye L, Hill G, Vega J, Tawil J, De Vry D, et al. Noninvasive Determination of Vortex Formation Time Using Transesophageal Echocardiography During Cardiac Surgery. J Vis Exp. 2018;: pubmed publisher
    ..The technique may allow cardiac anesthesiologists and surgeons to assess the impact of pathological conditions and surgical interventions on LV filling efficiency in real time. ..
  4. Pagel P, Krolikowski J, Pratt P, Shim Y, Amour J, Warltier D, et al. Inhibition of glycogen synthase kinase or the apoptotic protein p53 lowers the threshold of helium cardioprotection in vivo: the role of mitochondrial permeability transition. Anesth Analg. 2008;107:769-75 pubmed publisher
    ..Inhibition of GSK or p53 lowers the threshold of helium-induced preconditioning via a mPTP-dependent mechanism in vivo. ..
  5. Pagel P, Dye L, Boettcher B, Freed J. Advanced Age Attenuates Left Ventricular Filling Efficiency Quantified Using Vortex Formation Time: A Study of Octogenarians With Normal Left Ventricular Systolic Function Undergoing Coronary Artery Surgery. J Cardiothorac Vasc Anesth. 2018;32:1775-1779 pubmed publisher
    ..0627 × age + 8.24; r2 = 0.408; p = 0.0139). The results indicate that LV filling efficiency quantified using VFT is reduced in octogenarians compared with younger patients undergoing coronary artery bypass grafting. ..
  6. Hudetz J, Patterson K, Iqbal Z, Gandhi S, Pagel P. Remote ischemic preconditioning prevents deterioration of short-term postoperative cognitive function after cardiac surgery using cardiopulmonary bypass: results of a pilot investigation. J Cardiothorac Vasc Anesth. 2015;29:382-8 pubmed publisher
  7. Pagel P, Hudetz J. Bibliometric analysis of anaesthesia journal editorial board members: correlation between journal impact factor and the median h-index of its board members. Br J Anaesth. 2011;107:357-61 pubmed publisher
    ..European editorial board members had higher h-index values than their American colleagues. The results suggest that editorial board members of anaesthesia journals with higher IFs have higher h-indices. ..
  8. Pagel P, Hudetz J. An analysis of scholarly productivity in United States academic anaesthesiologists by citation bibliometrics. Anaesthesia. 2011;66:873-8 pubmed publisher
    ..You can respond to this article at http://www.anaesthesiacorrespondence.com. ..
  9. Pagel P, Hudetz J. Recent trends in publication of basic science and clinical research by United States investigators in anesthesia journals. BMC Anesthesiol. 2012;12:5 pubmed publisher
    ..An increase in clinical but not basic science research was observed in 2010 compared with 2007, suggesting that a modest recovery in clinical research production may have begun. ..

More Information


  1. Pagel P, Boettcher B, De Vry D, Freed J, Iqbal Z. Moderate Aortic Valvular Insufficiency Invalidates Vortex Formation Time as an Index of Left Ventricular Filling Efficiency in Patients With Severe Degenerative Calcific Aortic Stenosis Undergoing Aortic Valve Replacement. J Cardiothorac Vasc Anesth. 2016;30:1260-5 pubmed publisher
    ..Moderate AI falsely elevates VFT in patients with severe AS undergoing AVR by partially inhibiting mitral valve opening. VFT may be an unreliable index of LV filling efficiency with competitive diastolic flow into the LV. ..
  2. Pagel P. Demographics and Scholarly Productivity of American Board of Anesthesiology Volunteers: Results of an Internet-Based Bibliometric Analysis. J Cardiothorac Vasc Anesth. 2016;30:1396-403 pubmed publisher
    ..These results indicated that ABA volunteers are leaders in anesthesiology with established records of administrative, educational, and scholarly accomplishment. ..
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    Pagel P, Toller W, Gross E, Gare M, Kersten J, Warltier D. K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion. Am J Physiol Heart Circ Physiol. 2000;279:H2574-9 pubmed
    ..No differences in hemodynamics or coronary collateral blood flow (through radioactive microspheres) were observed among groups. The results indicate that K(ATP) channels mediate the protective effects of chronic consumption of ethanol...
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    Pagel P, Krolikowski J, Shim Y, Venkatapuram S, Kersten J, Weihrauch D, et al. Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. Anesth Analg. 2007;105:562-9 pubmed
  5. Pagel P, Hudetz J. Chronic pressure-overload hypertrophy attenuates vortex formation time in patients with severe aortic stenosis and preserved left ventricular systolic function undergoing aortic valve replacement. J Cardiothorac Vasc Anesth. 2013;27:660-4 pubmed publisher
    ..57 ×PWT + 6.81; r(2) = 0.345; p = 0.017). The results indicated that pressure-overload hypertrophy produced by AS reduced VFT in patients with normal LV systolic function undergoing aortic valve replacement. ..