Michael Foster Olive

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc Glutamatergic targets for enhancing extinction learning in drug addiction
    R M Cleva
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, 29425, USA
    Curr Neuropharmacol 8:394-408. 2010
  2. pmc Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences Medical University of South Carolina, Charleston, SC 29425 USA
    Alcohol 42:191-7. 2008
  3. pmc Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice
    Michael Foster Olive
    Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Behav Pharmacol 21:493-9. 2010
  4. pmc Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Eur J Pharmacol 639:47-58. 2010
  5. pmc Metabotropic glutamate receptor ligands as potential therapeutics for addiction
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Curr Drug Abuse Rev 2:83-98. 2009
  6. pmc N-Acetylcysteine reverses cocaine-induced metaplasticity
    Khaled Moussawi
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Avenue BSB410, Charleston, South Carolina, USA
    Nat Neurosci 12:182-9. 2009
  7. ncbi request reprint Reinstatement of ethanol-seeking behavior following intravenous self-administration in Wistar rats
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 31:1441-5. 2007
  8. ncbi request reprint The safety of disulfiram for the treatment of alcohol and cocaine dependence in randomized clinical trials: guidance for clinical practice
    Robert Malcolm
    Medical University of South Carolina, Institute of Psychiatry, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Expert Opin Drug Saf 7:459-72. 2008
  9. pmc Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Addict Biol 16:215-28. 2011
  10. pmc Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 204:587-97. 2009

Collaborators

Detail Information

Publications28

  1. pmc Glutamatergic targets for enhancing extinction learning in drug addiction
    R M Cleva
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, 29425, USA
    Curr Neuropharmacol 8:394-408. 2010
    ..These classes of cognition-enhancing compounds could potentially serve as novel pharmacological adjuncts to cue exposure therapy to increase success rates in attenuating cue-induced drug craving and relapse...
  2. pmc Effects of the mGluR2/3 agonist LY379268 and the mGluR5 antagonist MPEP on handling-induced convulsions during ethanol withdrawal in mice
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences Medical University of South Carolina, Charleston, SC 29425 USA
    Alcohol 42:191-7. 2008
    ....
  3. pmc Protein kinase C isozymes as regulators of sensitivity to and self-administration of drugs of abuse-studies with genetically modified mice
    Michael Foster Olive
    Department of Psychiatry, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Behav Pharmacol 21:493-9. 2010
    ....
  4. pmc Cognitive effects of Group I metabotropic glutamate receptor ligands in the context of drug addiction
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Eur J Pharmacol 639:47-58. 2010
    ....
  5. pmc Metabotropic glutamate receptor ligands as potential therapeutics for addiction
    M Foster Olive
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Curr Drug Abuse Rev 2:83-98. 2009
    ..Finally, we will discuss the current status of mGluR ligands in human clinical trials...
  6. pmc N-Acetylcysteine reverses cocaine-induced metaplasticity
    Khaled Moussawi
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Avenue BSB410, Charleston, South Carolina, USA
    Nat Neurosci 12:182-9. 2009
    ..Our findings show that cocaine self-administration induces metaplasticity that inhibits further induction of synaptic plasticity, and this impairment can be reversed by NAC, a drug that also prevents relapse...
  7. ncbi request reprint Reinstatement of ethanol-seeking behavior following intravenous self-administration in Wistar rats
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 31:1441-5. 2007
    ..However, no studies to date have examined reinstatement of ethanol-seeking behavior in animals with a history of IV ethanol self-administration...
  8. ncbi request reprint The safety of disulfiram for the treatment of alcohol and cocaine dependence in randomized clinical trials: guidance for clinical practice
    Robert Malcolm
    Medical University of South Carolina, Institute of Psychiatry, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Expert Opin Drug Saf 7:459-72. 2008
    ..Disulfiram has demonstrated efficacy in six randomized clinical trials for the treatment of cocaine dependence, but is rarely used in clinical settings because of safety concerns...
  9. pmc Alcohol-seeking behavior is associated with increased glutamate transmission in basolateral amygdala and nucleus accumbens as measured by glutamate-oxidase-coated biosensors
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Addict Biol 16:215-28. 2011
    ..These results indicate that increases in glutamate transmission in the BLA and NAc core may be a neurochemical substrate of cue-evoked alcohol-seeking behavior...
  10. pmc Role of protein kinase C epsilon (PKCvarepsilon) in the reduction of ethanol reinforcement due to mGluR5 antagonism in the nucleus accumbens shell
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, MSC 861, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 204:587-97. 2009
    ....
  11. pmc Glutamatergic substrates of drug addiction and alcoholism
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Biochem Pharmacol 75:218-65. 2008
    ..Nonetheless, manipulation of glutamatergic neurotransmission appears to be a promising avenue of research in developing improved therapeutic agents for the treatment of drug addiction and alcoholism...
  12. pmc mGluR5 antagonism attenuates methamphetamine reinforcement and prevents reinstatement of methamphetamine-seeking behavior in rats
    Justin T Gass
    Department of Psychiatry and Behavioral Sciences, Center for Drug and Alcohol Programs, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuropsychopharmacology 34:820-33. 2009
    ....
  13. pmc Positive allosteric modulation of mGluR5 receptors facilitates extinction of a cocaine contextual memory
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Biol Psychiatry 65:717-20. 2009
    ..The perseverance of the motivational salience of drug-associated memories is an obstacle to the successful treatment of drug addiction and is often a causative factor in triggering relapse...
  14. pmc Transcriptional profiling of the rat frontal cortex following administration of the mGlu5 receptor antagonists MPEP and MTEP
    Justin T Gass
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC, 29425, USA
    Eur J Pharmacol 584:253-62. 2008
    ....
  15. doi request reprint A role for mGluR5 receptors in intravenous methamphetamine self-administration
    Megan P H Osborne
    Center for Drug and Alcohol Programs, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina, USA
    Ann N Y Acad Sci 1139:206-11. 2008
    ..These data suggest that mGluR5 receptors are involved in the reinforcing effects of methamphetamine, and that antagonists of this receptor may serve as novel pharmacologic agents for the treatment of addiction to methamphetamine...
  16. ncbi request reprint Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release
    M Foster Olive
    Ernest Gallo Clinic and Research Center, UCSF Department of Neurology, 5858 Horton Street, Suite 200, Emeryville, CA 94608, USA
    Eur J Pharmacol 437:55-61. 2002
    ....
  17. ncbi request reprint The mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine decreases ethanol consumption via a protein kinase C epsilon-dependent mechanism
    M Foster Olive
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, 5858 Horton St, Suite 200, Emeryville, CA 94608, USA
    Mol Pharmacol 67:349-55. 2005
    ..Our data indicate that mGluR5 is coupled to PKCepsilon via a PI3K-dependent pathway and that PKCepsilon is required for the ability of the mGluR5 antagonist MPEP to reduce ethanol consumption...
  18. ncbi request reprint The mGluR5 antagonist MPEP reduces the conditioned rewarding effects of cocaine but not other drugs of abuse
    Andrew J McGeehan
    Department of Neurology, University of California at San Francisco, Emeryville, California 94608, USA
    Synapse 47:240-2. 2003
    ..When tested alone at the doses effective in reducing CPP, MPEP produced neither a place preference nor aversion. These data provide further support for a role of the mGluR5 receptor in the rewarding effects of cocaine...
  19. ncbi request reprint Effect of the mGluR5 antagonist 6-methyl-2-(phenylethynyl)pyridine (MPEP) on the acute locomotor stimulant properties of cocaine, D-amphetamine, and the dopamine reuptake inhibitor GBR12909 in mice
    Andrew J McGeehan
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California at San Francisco, 5858 Horton Street, Suite 200, Emeryville, CA 94608, USA
    Psychopharmacology (Berl) 174:266-73. 2004
    ....
  20. ncbi request reprint Elevated extracellular CRF levels in the bed nucleus of the stria terminalis during ethanol withdrawal and reduction by subsequent ethanol intake
    M Foster Olive
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California, San Francisco, 5858 Horton Street, Suite 200, Emeryville, CA 94608, USA
    Pharmacol Biochem Behav 72:213-20. 2002
    ..These data demonstrate that extracellular CRF levels are increased in the BNST during ethanol withdrawal, and that these increases are reduced by subsequent ethanol intake...
  21. ncbi request reprint The corticotropin-releasing factor/urocortin system and alcohol
    Andrey E Ryabinin
    Department of Behavioral Neuroscience, Oregon Health and Sciences University, Portland 97201 3098, USA
    Alcohol Clin Exp Res 26:714-22. 2002
    ..Mehmert, R. Camarini, Joseph A. Kim, Heather N. Koenig, Michelle A. Nannini, and Clyde W. Hodge; and (5) Selective sensitivity of urocortin-containing neurons to alcohol self-administration, by Andrey E. Ryabinin and Ryan K. Bachtell...
  22. pmc The anti-relapse compound acamprosate inhibits the development of a conditioned place preference to ethanol and cocaine but not morphine
    Andrew J McGeehan
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, 5858 Horton Street, Emeryville, CA 94608, U S A
    Br J Pharmacol 138:9-12. 2003
    ..These data suggest that acamprosate can suppress the conditioned rewarding effects of ethanol and certain classes of abused substances...
  23. ncbi request reprint Alcohol addiction
    M Foster Olive
    Department of Neurology, Ernest Gallo Clinic and Research Center, University of California, San Francisco, Emeryville, USA
    Methods Mol Biol 233:555-70. 2003
  24. ncbi request reprint The anti-craving taurine derivative acamprosate: failure to extinguish morphine conditioned place preference
    M Foster Olive
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, California, USA
    Adv Exp Med Biol 526:481-4. 2003
  25. ncbi request reprint The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions
    Heather N Koenig
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, 5858 Horton Street, Suite 200, Emeryville, CA 94608, USA
    Psychoneuroendocrinology 29:999-1003. 2004
    ..p.) was without effect on ethanol intake, and neither compound had an effect on water intake. These data confirm an active role of GRs in modulating voluntary ethanol consumption, particularly under conditions of limited access...
  26. ncbi request reprint Role of the endogenous opioid system on the neuropsychopharmacological effects of ethanol: new insights about an old question
    Carles Sanchis-Segura
    Howard Florey Institute, University of Melbourne, Australia
    Alcohol Clin Exp Res 29:1522-7. 2005
    ..Grisel, Amanda J. Roberts, and George F. Koob; and () The mu-Opioid Receptor Modulates Acute Ethanol Sensitivity and Ethanol Withdrawal Severity by Sandra Ghozland...
  27. ncbi request reprint Acamprosate attenuates cocaine- and cue-induced reinstatement of cocaine-seeking behavior in rats
    M Scott Bowers
    Ernest Gallo Clinic and Research Center, Department of Neurology, University of California at San Francisco, Emeryville, CA 94608, USA
    Psychopharmacology (Berl) 195:397-406. 2007
    ..Acamprosate (calcium acetylhomotaurinate) is a glutamatergic neuromodulator used for the treatment of alcoholism, but its potential efficacy in the treatment of psychostimulant addiction has not been explored...
  28. doi request reprint A microdialysis study of extracellular levels of acamprosate and naltrexone in the rat brain following acute and repeated administration
    Costanza Burattini
    University of California, San Francisco, USA
    Addict Biol 13:70-9. 2008
    ....

Research Grants10

  1. Taurine Regulation of Alcohol-Seeking Behavior
    M Olive; Fiscal Year: 2004
    ..abstract_text> ..
  2. Control of ethanol intake by mGluR5-PKCepsilon pathway
    M Olive; Fiscal Year: 2007
    ..Together, these proposed preclinical studies will attempt to delineate a novel pharmacological target that may be used to treat various aspects of alcohol abuse and alcoholism. ..
  3. Control of Ethanol Intake by an mGluR5-PKCe Pathway
    M Olive; Fiscal Year: 2009
    ..Further understanding of the contributions of mGluR5 and PKC5 signaling to these behaviors will hopefully translate into improved therapies for the treatment of alcoholism in humans. ..
  4. Metabotropic Glutamate Receptor Signaling and Extinction Learning
    M Olive; Fiscal Year: 2009
    ..Such compounds could also be of potential use in extinction therapy of anxiety disorders such as post-traumatic stress disorder. ..
  5. Metabotropic Glutamate Receptor Signaling and Extinction Learning
    M Olive; Fiscal Year: 2007
    ..Such compounds could also be of potential use in extinction therapy of anxiety disorders such as post-traumatic stress disorder. ..
  6. mGluR5 antagonists for methamphetamine addiction
    M Olive; Fiscal Year: 2009
    ....