Alfred Nicolosi

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Gadolinium prevents stretch-mediated contractile dysfunction in isolated papillary muscles
    A C Nicolosi
    Department of Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Heart Circ Physiol 280:H1122-8. 2001
  2. ncbi request reprint Invited commentary
    Alfred Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 W Wisconsin Ave, Milwaukee, WI 53226 0099, USA
    Ann Thorac Surg 84:822. 2007
  3. ncbi request reprint Effects of gadolinium on regionally stunned myocardium: temporal considerations
    Alfred C Nicolosi
    Department of Surgery Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Surg Res 139:286-91. 2007
  4. pmc Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Mol Cell Cardiol 44:345-51. 2008
  5. ncbi request reprint Gadolinium attenuates regional stunning in the canine heart in vivo
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, USA
    J Thorac Cardiovasc Surg 124:57-62. 2002
  6. ncbi request reprint Perioperative considerations in the patient with a left ventricular assist device
    Alfred C Nicolosi
    Department of Surgery Division of Cardiothoracic Surgery, The Medical College of Wisconsin and the Clement J Zablocki Veterans Affairs Medical Center, Milwaukee 53226, USA
    Anesthesiology 98:565-70. 2003
  7. ncbi request reprint Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels
    Hiroto Miura
    Department of Veterans Affairs Medical Center, Milwaukee, Wis, USA
    Circ Res 92:151-8. 2003
  8. ncbi request reprint Antagonists of stretch-activated ion channels restore contractile function in hamster dilated cardiomyopathy
    Alfred C Nicolosi
    Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    J Heart Lung Transplant 23:1003-7. 2004
  9. ncbi request reprint Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries
    Yanping Liu
    Department of Internal Medicine, Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, Wis 53226, USA
    Circ Res 93:573-80. 2003
  10. ncbi request reprint Mechanism of thrombin-induced vasodilation in human coronary arterioles
    John J Bosnjak
    Medical College of Wisconsin, Cardiovascular Center, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Heart Circ Physiol 284:H1080-6. 2003

Collaborators

Detail Information

Publications14

  1. ncbi request reprint Gadolinium prevents stretch-mediated contractile dysfunction in isolated papillary muscles
    A C Nicolosi
    Department of Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Heart Circ Physiol 280:H1122-8. 2001
    ..64 +/- 0.05), but DHP did not (T(max) = 0.48 +/- 0.04). These data suggest that overstretching of the myocardium contributes to contractile abnormalities via SA channels that are distinct from L-type calcium channels...
  2. ncbi request reprint Invited commentary
    Alfred Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, Froedtert Memorial Lutheran Hospital, 9200 W Wisconsin Ave, Milwaukee, WI 53226 0099, USA
    Ann Thorac Surg 84:822. 2007
  3. ncbi request reprint Effects of gadolinium on regionally stunned myocardium: temporal considerations
    Alfred C Nicolosi
    Department of Surgery Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Surg Res 139:286-91. 2007
    ..This study sought to determine whether giving Gd(3+) during ischemia or during reperfusion also ameliorates stunning, as these temporal relationships could help determine the clinical utility of this novel agent...
  4. pmc Gadolinium limits myocardial infarction in the rat: dose-response, temporal relations and mechanisms
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Mol Cell Cardiol 44:345-51. 2008
    ..The mechanism underlying Gd-induced preconditioning appears to be multi-factorial, involving JAK-2, STAT-3 and p44 MAPK pathways, as well as K(ATP) channels...
  5. ncbi request reprint Gadolinium attenuates regional stunning in the canine heart in vivo
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, USA
    J Thorac Cardiovasc Surg 124:57-62. 2002
    ..The present study tested the hypothesis that gadolinium would also attenuate regional myocardial stunning in an in vivo model...
  6. ncbi request reprint Perioperative considerations in the patient with a left ventricular assist device
    Alfred C Nicolosi
    Department of Surgery Division of Cardiothoracic Surgery, The Medical College of Wisconsin and the Clement J Zablocki Veterans Affairs Medical Center, Milwaukee 53226, USA
    Anesthesiology 98:565-70. 2003
  7. ncbi request reprint Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels
    Hiroto Miura
    Department of Veterans Affairs Medical Center, Milwaukee, Wis, USA
    Circ Res 92:151-8. 2003
    ..We conclude that DM impairs human coronary arteriolar dilation to K(ATP) opening, leading to reduced dilation to hypoxia. This reduction in K(ATP) function could contribute to the greater cardiovascular mortality and morbidity in DM...
  8. ncbi request reprint Antagonists of stretch-activated ion channels restore contractile function in hamster dilated cardiomyopathy
    Alfred C Nicolosi
    Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    J Heart Lung Transplant 23:1003-7. 2004
    ..We hypothesized that SAC antagonists would enhance contractile function in a hamster model of DCM...
  9. ncbi request reprint Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries
    Yanping Liu
    Department of Internal Medicine, Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, Wis 53226, USA
    Circ Res 93:573-80. 2003
    ..05). Neither cyanide nor apocynin altered flow-induced dilation. These results suggest that shear stress induced H2O2 formation, and flow-induced dilation is derived from O2*- originating from mitochondrial respiration...
  10. ncbi request reprint Mechanism of thrombin-induced vasodilation in human coronary arterioles
    John J Bosnjak
    Medical College of Wisconsin, Cardiovascular Center, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Heart Circ Physiol 284:H1080-6. 2003
    ..We speculate that an endothelium-derived hyperpolarizing factor contributes to Thromb-induced dilation in HCA...
  11. ncbi request reprint A novel approach to the management of tracheoinnominate artery fistula
    Mario G Gasparri
    Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Ann Thorac Surg 77:1424-6. 2004
    ..A 75-year-old gentleman with tracheoinnominate fistula is reported. The issues regarding the surgical approach to this problem are reviewed and a creation of an aorto-axillary bypass graft described...
  12. ncbi request reprint A widened mediastinum in a patient with a left parasternal stab wound
    Zafar Iqbal
    Department of Anesthesiology, Medical College of Wisconsin and Clement J Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53226, USA
    J Cardiothorac Vasc Anesth 21:307-9. 2007
  13. ncbi request reprint Perioperative implications of charcot-marie-tooth disease during coronary artery bypass graft surgery
    Vijayashree Shankar
    Department of Anesthesiology, Clement J Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53295, USA
    J Cardiothorac Vasc Anesth 21:567-9. 2007
  14. ncbi request reprint Increased incidence of radial artery calcification in patients with diabetes mellitus
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Surg Res 102:1-5. 2002
    ..We sought to determine the incidence of RA calcific disease in diabetic vs nondiabetic patients using ultrasonography to establish its role in preoperative evaluation of CAB patients...