COREY MJAATVEDT

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation
    C H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina, 29425, USA
    Dev Biol 202:56-66. 1998
  2. ncbi The outflow tract of the heart is recruited from a novel heart-forming field
    C H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA
    Dev Biol 238:97-109. 2001
  3. ncbi Een geslaagd jubileum! The 10th Weinstein Developmental Cardiovascular Conference in Leiden
    Corey H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
    Dev Dyn 231:655-9. 2004
  4. ncbi Normal distribution of melanocytes in the mouse heart
    Corey H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Anat Rec A Discov Mol Cell Evol Biol 285:748-57. 2005
  5. ncbi Detection of betaig-H3, a TGFbeta induced gene, during cardiac development and its complementary pattern with periostin
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Ave BSB 642, Charleston, SC 29425, USA
    Anat Embryol (Berl) 210:13-23. 2005
  6. ncbi Identification and detection of the periostin gene in cardiac development
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Anat Rec A Discov Mol Cell Evol Biol 281:1227-33. 2004
  7. ncbi Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development
    Elaine E Wirrig
    Department of Cell Biology and Anatomy, Cardiovascular Developmental Biology Center, Medical University of South Carolina, Charleston, SC 29425, USA
    Dev Biol 310:291-303. 2007
  8. ncbi Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase
    Jonathan T Butcher
    Cardiovascular Developmental Biology Center, Chair of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Dev Biol 302:256-66. 2007
  9. ncbi Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cell Biochem 101:695-711. 2007
  10. ncbi Versican proteolysis mediates myocardial regression during outflow tract development
    Christine B Kern
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425 2204, USA
    Dev Dyn 236:671-83. 2007

Research Grants

  1. Cspg2 Gene and Cardiac Outlet Morphogenesis
    COREY MJAATVEDT; Fiscal Year: 2005
  2. Cspg2 Gene and Cardiac Outlet Morphogenesis
    COREY MJAATVEDT; Fiscal Year: 2009
  3. Cspg2 Gene and Cardiac Outlet Morphogenesis
    Corey H Mjaatvedt; Fiscal Year: 2010

Collaborators

Detail Information

Publications19

  1. ncbi The Cspg2 gene, disrupted in the hdf mutant, is required for right cardiac chamber and endocardial cushion formation
    C H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina, 29425, USA
    Dev Biol 202:56-66. 1998
    ....
  2. ncbi The outflow tract of the heart is recruited from a novel heart-forming field
    C H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 171 Ashley Avenue, Charleston, South Carolina 29425, USA
    Dev Biol 238:97-109. 2001
    ..This new concept of the heart outlet's embryonic origin provides a new basis for explaining a variety of gene-expression patterns and cardiac defects described in both transgenic animals and human congenital heart disease...
  3. ncbi Een geslaagd jubileum! The 10th Weinstein Developmental Cardiovascular Conference in Leiden
    Corey H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
    Dev Dyn 231:655-9. 2004
  4. ncbi Normal distribution of melanocytes in the mouse heart
    Corey H Mjaatvedt
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Anat Rec A Discov Mol Cell Evol Biol 285:748-57. 2005
    ..If these cells are of neural crest origin, it would suggest a possibly greater contribution and persistence of neural crest cells to the valvuloseptal apparatus than has been previously understood...
  5. ncbi Detection of betaig-H3, a TGFbeta induced gene, during cardiac development and its complementary pattern with periostin
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Ave BSB 642, Charleston, SC 29425, USA
    Anat Embryol (Berl) 210:13-23. 2005
    ..The mRNA expression domains of betaig-H3 show a complementary pattern compared to that of its highly homologous relative, periostin...
  6. ncbi Identification and detection of the periostin gene in cardiac development
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Anat Rec A Discov Mol Cell Evol Biol 281:1227-33. 2004
    ..Cardiac expression continues into fetal development where periostin is seen predominantly in the valve leaflets and supporting chordae tendinae...
  7. ncbi Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development
    Elaine E Wirrig
    Department of Cell Biology and Anatomy, Cardiovascular Developmental Biology Center, Medical University of South Carolina, Charleston, SC 29425, USA
    Dev Biol 310:291-303. 2007
    ..Combined, these findings establish an important role for Crtl1 in heart development...
  8. ncbi Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase
    Jonathan T Butcher
    Cardiovascular Developmental Biology Center, Chair of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425, USA
    Dev Biol 302:256-66. 2007
    ..Taken together, these results highlight periostin as a mediator of matrix remodeling by cushion mesenchyme towards a mature valve structure...
  9. ncbi Periostin regulates collagen fibrillogenesis and the biomechanical properties of connective tissues
    Russell A Norris
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cell Biochem 101:695-711. 2007
    ..Collectively, these data demonstrate for the first time that periostin can regulate collagen I fibrillogenesis and thereby serves as an important mediator of the biomechanical properties of fibrous connective tissues...
  10. ncbi Versican proteolysis mediates myocardial regression during outflow tract development
    Christine B Kern
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, SC 29425 2204, USA
    Dev Dyn 236:671-83. 2007
    ..Taken together, we conclude that intact versican and G1-containing versican cleavage products have opposing effects on myocardial cells and that versican proteolysis may facilitate the loss of distal myocardium during OFT remodeling...
  11. ncbi Proteolytic cleavage of versican during cardiac cushion morphogenesis
    Christine B Kern
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Dev Dyn 235:2238-47. 2006
    ..Together, the findings reveal that versican proteolysis leading to the production of the 70-kDa fragment is integral to the formation and differentiation of endocardial cushion mesenchyme...
  12. ncbi Fibulin-1 is required for morphogenesis of neural crest-derived structures
    Marion A Cooley
    Department of Cell Biology and Anatomy, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
    Dev Biol 319:336-45. 2008
    ....
  13. ncbi Immunolocalization of chick periostin protein in the developing heart
    Christine B Kern
    Department of Cell Biology and Anatomy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Anat Rec A Discov Mol Cell Evol Biol 284:415-23. 2005
    ..We propose that periostin is induced by sheer stress and may be an essential molecular component for structures of the heart that undergo mechanical stress or tension during the cardiac cycle...
  14. ncbi Hot hearts in the Sonoran Desert: the 11th Weinstein Cardiovascular Development Conference in Tucson
    Katharine M Hardy
    Department of Cell Biology and Anatomy, University of Arizona, Tucson, Arizona 85724, USA
    Dev Dyn 235:170-5. 2006
    ..1), and liberal use of a cattle prod to encourage speaker timeliness...
  15. ncbi GATA factors lie upstream of Nkx 2.5 in the transcriptional regulatory cascade that effects cardiogenesis
    Alison C Brewer
    Department of Cardiology, King s College Hospital, London SE5 9RS, UK
    Stem Cells Dev 14:425-39. 2005
    ....
  16. ncbi An in vitro method for analysis of chondrogenesis in limb mesenchyme from individual transgenic (hdf) embryos
    Danielle M Gillotte
    Department of Biology, East Carolina University, Greenville, NC 27858, USA
    Methods Cell Sci 25:97-104. 2003
    ....
  17. ncbi Versican expression during skeletal/joint morphogenesis and patterning of muscle and nerve in the embryonic mouse limb
    Holly E Snow
    Department of Biology, East Carolina University, Greenville, North Carolina 27858, USA
    Anat Rec A Discov Mol Cell Evol Biol 282:95-105. 2005
    ..Versican-expressing tissues may reserve space for the future limb skeleton and developing joints and may aid in patterning of muscle and nerve by deterring muscle migration and innervation into these regions...
  18. ncbi Limb chondrogenesis is compromised in the versican deficient hdf mouse
    Dennis R Williams
    Department of Biology, East Carolina University, Greenville, NC, USA
    Biochem Biophys Res Commun 334:960-6. 2005
    ..Results strongly suggest that mature versican proteoglycan is essential for precartilage aggregation and subsequent cartilage differentiation...
  19. ncbi Characterization of the cardiac phenotype in neonatal Ts65Dn mice
    Austin D Williams
    Biology Department, Franklin and Marshall College, Lancaster, Pennsylvania 17604 3003, USA
    Dev Dyn 237:426-35. 2008
    ..The candidate genes for congenital heart defects that are among the 104 triplicated genes in Ts65Dn mice are, therefore, implicated in the dysregulation of normal cardiogenic pathways in this model...

Research Grants8

  1. Cspg2 Gene and Cardiac Outlet Morphogenesis
    COREY MJAATVEDT; Fiscal Year: 2005
    ....
  2. Cspg2 Gene and Cardiac Outlet Morphogenesis
    COREY MJAATVEDT; Fiscal Year: 2009
    ..The V2/V0 null mouse in this proposal provides the first mammalian model in which we can directly investigate the role of versican in the heart at developmental stages that directly impact clinically relevant live birth heart defects. ..
  3. Cspg2 Gene and Cardiac Outlet Morphogenesis
    Corey H Mjaatvedt; Fiscal Year: 2010
    ..The V2/V0 null mouse in this proposal provides the first mammalian model in which we can directly investigate the role of versican in the heart at developmental stages that directly impact clinically relevant live birth heart defects. ..