Research Topics
| Michael E MitchellSummaryAffiliation: Medical College of Wisconsin Country: USA Publications
| Collaborators
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Detail Information
Publications
Human gene copy number spectra analysis in congenital heart malformationsAoy Tomita-Mitchell
Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Physiol Genomics 44:518-41. 2012..3% had likely causal (significantly enriched), large, rare CNVs. CNV frequency spectra combined with precision phenotyping may lead to increased molecular understanding of etiologic pathways...- Multiplexed quantitative real-time PCR to detect 22q11.2 deletion in patients with congenital heart diseaseAoy Tomita-Mitchell
Division of Cardiovascular Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Physiol Genomics 42:52-60. 2010..The MQPCR assay is a rapid, inexpensive, sensitive, and specific assay that can be used to screen for 22q11.2 deletion syndrome. The assay is readily adaptable to high throughput... 
Near-infrared spectroscopy in neonates before palliation of hypoplastic left heart syndromeBeth Ann Johnson
Herma Heart Center, Children s Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA
Ann Thorac Surg 87:571-7; discussion 577-9. 2009..We hypothesized that preoperative use of near-infrared spectroscopy (NIRS) would reduce the need for invasive therapies, including controlled ventilation and inspired gas manipulation...- Perioperative monitoring in high-risk infants after stage 1 palliation of univentricular congenital heart diseaseNancy S Ghanayem
Herma Heart Center at the Children s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI 53226, USA
J Thorac Cardiovasc Surg 140:857-63. 2010..We hypothesized that early goal-directed monitoring with venous oximetry and near-infrared spectroscopy would offset their increased vulnerability and improve survival... 
Mixed venous oxygen saturation monitoring after stage 1 palliation for hypoplastic left heart syndromeJames S Tweddell
Herma Heart Center and Children s Research Institute, Children s Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA
Ann Thorac Surg 84:1301-10; discussion 1310-1. 2007....- Aortic valve replacement in neonates and infants: an analysis of the Society of Thoracic Surgeons Congenital Heart Surgery DatabaseRonald K Woods
Department of Surgery, Cardiothoracic Surgery, Children s Hospital Wisconsin, Medical College of Wisconsin, Milwaukee, WI, USA
J Thorac Cardiovasc Surg 144:1084-89. 2012..We sought to describe early outcomes of aortic valve replacement in neonates and infants across a large multicenter cohort... - Non-invasive prenatal detection of trisomy 21 using tandem single nucleotide polymorphismsSujana Ghanta
Division of Cardiothoracic Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
PLoS ONE 5:e13184. 2010..We outline a novel, rapid, highly sensitive, and targeted approach to non-invasively detect fetal T21 using maternal plasma DNA... - The molecular basis of congenital heart diseaseMichael E Mitchell
Department of Surgery, Division of Cardiothoracic Surgery, Medical College of Wisconsin, Children s Hospital of Wisconsin, and Children s Research Institute, Milwaukee, Wisconsin 53226, USA
Semin Thorac Cardiovasc Surg 19:228-37. 2007..Because the majority of cases occur without known cause, the molecular basis of CHD is an active and evolving discussion... - Coarctectomy combined with an interdigitating arch reconstruction results in a lower incidence of recurrent arch obstruction after the Norwood procedure than coarctectomy aloneLuke J Lamers
Section of Pediatric Cardiology, Department of Pediatrics, The Medical College of Wisconsin, Milwaukee, WI, USA
J Thorac Cardiovasc Surg 143:1098-102. 2012..We sought to determine if a modified interdigitating technique for aortic arch reconstruction during the Norwood procedure decreased recurrent arch obstruction... - Fontan palliation in the modern era: factors impacting mortality and morbidityJames S Tweddell
Division of Cardiothoracic Surgery, Department of Surgery, Sections of Pediatric Cardiology and Critical Care, Medical College of Wisconsin and Herma Heart Center, Children s Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA
Ann Thorac Surg 88:1291-9. 2009..Coincident with these improvements, Fontan palliation has been applied to a wider ranger of anatomic subgroups... - Valve-sparing aortic root reconstruction in children, teenagers, and young adultsJames S Tweddell
Division of Cardiothoracic Surgery, Department of Surgery, Children s Hospital of Wisconsin, Milwaukee, Wisconsin 53226, USA
Ann Thorac Surg 94:587-90; discussion 590-1. 2012..We reviewed our experience with valve-sparing aortic root reconstruction (VSARR) using the sinus of Valsalva graft in children, teenagers, and young adults with connective tissue disorders... - Creation and implementation of a prospective pediatric clinical outcomes registryLaura D Cassidy
Medical College of Wisconsin, Milwaukee, WI, USA
J Registry Manag 38:138-43. 2011..To build a pediatric clinical outcomes registry (COR) using a contemporary information system designed to support research and outcome studies and to improve patient care and quality of life... - Surgery and critical care for anomalous coronary artery from the pulmonary arteryTimothy A Fehrenbacher
Division of Cardiothoracic Surgery, Department of Surgery and Section of Critical Care, Herma Heart Center, Children s Hospital of Wisconsin, Medical College of Wisconsin, Wisconsin 53226, United States of America
Cardiol Young 20:35-43. 2010..Mechanical support, with either extracorporeal membrane oxygenation or left ventricular assist device, should be available for use if necessary... - Monitoring the brain before, during, and after cardiac surgery to improve long-term neurodevelopmental outcomesNancy S Ghanayem
Department of Pediatrics, Division of Cardiothoracic Surgery, Medical College of Wisconsin 53122, USA
Cardiol Young 16:103-9. 2006 - Candidate urinary biomarker discovery in ureteropelvic junction obstruction: a proteomic approachHrair George O Mesrobian
Department of Urology, Medical College and Children s Hospital of Wisconsin, Milwaukee, Wisconsin, USA
J Urol 184:709-14. 2010..We sought to confirm these findings using liquid chromatography/nano-spray mass spectrometry to examine the urinary proteome in patients with unilateral grade IV ureteropelvic junction obstruction compared to age matched healthy infants... - Molecular and cellular basis of congenital heart diseaseTara L Sander
Department of Surgery, Division of Pediatric Surgery, Cardiovascular Research Center, Children s Research Institute and Medical College of Wisconsin, Children s Hospital of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Pediatr Clin North Am 53:989-1009, x. 2006..Such understanding will lead to the development of novel approaches to prevention and therapy... - Intermediate outcomes after the Fontan procedure in the current eraMichael E Mitchell
Department of Surgery, Division of Cardiothoracic Surgery, University of Louisville, Louisville, KY 40202, USA
J Thorac Cardiovasc Surg 131:172-80. 2006..This study was undertaken to investigate the intermediate outcomes after the Fontan operation in the current era...