J E Mintzer

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi A comparison of extrapyramidal symptoms in older outpatients treated with quetiapine or risperidone
    Jacobo E Mintzer
    Medical University of South Carolina, Institute of Psychiatry, Charleston, SC 29406 6076, USA
    Curr Med Res Opin 20:1483-91. 2004
  2. ncbi Aripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed doses
    Jacobo E Mintzer
    Alzheimer s Research and Clinical Programs, Medical University of South Carolina, North Charleston, SC 29406 6076, USA
    Am J Geriatr Psychiatry 15:918-31. 2007
  3. ncbi Olanzapine in the treatment of anxiety symptoms due to Alzheimer's disease: a post hoc analysis
    J Mintzer
    Medical University of South Carolina, Alzheimer s Research and Clinical Programs Charleston, SC 29406 6076, USA
    Int J Geriatr Psychiatry 16:S71-7. 2001
  4. ncbi Introduction: the clinical impact of agitation in various psychiatric disorders: management consensus and controversies
    Jacobo E Mintzer
    Department of Psychiatry, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 67:3-5. 2006
  5. ncbi The efficacy of galantamine in the treatment of Alzheimer's disease: comparison of patients previously treated with acetylcholinesterase inhibitors to patients with no prior exposure
    J E Mintzer
    Medical University of South Carolina, N Charleston, South Carolina, USA
    Int J Geriatr Psychiatry 18:292-7. 2003
  6. ncbi The search for better noncholinergic treatment options for Alzheimer's disease
    Jacobo E Mintzer
    Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, SC, USA
    J Clin Psychiatry 64:18-22. 2003
  7. ncbi Psychosis in elderly patients: classification and pharmacotherapy
    Jacobo Mintzer
    Medical University of South Carolina, Institute of Psychiatry, Charleston 29406, USA
    J Geriatr Psychiatry Neurol 16:199-206. 2003
  8. ncbi What are the challenges faced by psychiatrists in the management of Alzheimer's disease?
    Jacobo E Mintzer
    Medical University of Sourth Carolina, 5900 Core Road, Charleston, SC 29406, USA
    CNS Spectr 9:13-5. 2004
  9. ncbi Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group
    I R Katz
    Department of Psychiatry, University of Pennsylvania Medical School, Philadelphia 19104, USA
    J Clin Psychiatry 60:107-15. 1999
  10. ncbi Underlying mechanisms of psychosis and aggression in patients with Alzheimer's disease
    J E Mintzer
    Department of Psychiatry, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 62:23-5. 2001

Research Grants

  1. Institute for Research Minority Training on Mental Health
    Jacobo Mintzer; Fiscal Year: 2006
  2. Depressoin in Alzheimer's Disease Study-2 (DIADS-2)
    Jacobo Mintzer; Fiscal Year: 2007
  3. Institute for Research Minority Training on Mental Health
    Jacobo Mintzer; Fiscal Year: 2007
  4. Apathy in Alzheimer's Disease Methylphenidate Trial
    Jacobo Mintzer; Fiscal Year: 2009
  5. Apathy in Alzheimer's Disease Methylphenidate Trial
    Paul B Rosenberg; Fiscal Year: 2010

Detail Information

Publications23

  1. ncbi A comparison of extrapyramidal symptoms in older outpatients treated with quetiapine or risperidone
    Jacobo E Mintzer
    Medical University of South Carolina, Institute of Psychiatry, Charleston, SC 29406 6076, USA
    Curr Med Res Opin 20:1483-91. 2004
    ..To compare the tolerability of quetiapine with risperidone in older outpatients...
  2. ncbi Aripiprazole for the treatment of psychoses in institutionalized patients with Alzheimer dementia: a multicenter, randomized, double-blind, placebo-controlled assessment of three fixed doses
    Jacobo E Mintzer
    Alzheimer s Research and Clinical Programs, Medical University of South Carolina, North Charleston, SC 29406 6076, USA
    Am J Geriatr Psychiatry 15:918-31. 2007
    ..To assess the efficacy and safety of aripiprazole for psychosis associated with Alzheimer dementia (AD)...
  3. ncbi Olanzapine in the treatment of anxiety symptoms due to Alzheimer's disease: a post hoc analysis
    J Mintzer
    Medical University of South Carolina, Alzheimer s Research and Clinical Programs Charleston, SC 29406 6076, USA
    Int J Geriatr Psychiatry 16:S71-7. 2001
    ..Although new information has emerged in recent years on the treatment of psychosis and agitation in dementia, very little information is available about the treatment of anxiety symptoms in this population...
  4. ncbi Introduction: the clinical impact of agitation in various psychiatric disorders: management consensus and controversies
    Jacobo E Mintzer
    Department of Psychiatry, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 67:3-5. 2006
  5. ncbi The efficacy of galantamine in the treatment of Alzheimer's disease: comparison of patients previously treated with acetylcholinesterase inhibitors to patients with no prior exposure
    J E Mintzer
    Medical University of South Carolina, N Charleston, South Carolina, USA
    Int J Geriatr Psychiatry 18:292-7. 2003
    ..With more AChEIs now available, treatment considerations may include whether the patient has had prior exposure to an AChEI...
  6. ncbi The search for better noncholinergic treatment options for Alzheimer's disease
    Jacobo E Mintzer
    Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, SC, USA
    J Clin Psychiatry 64:18-22. 2003
    ..These treatments, supplemented with current cholinergic therapies, may help to ease patients' suffering and caregiver distress...
  7. ncbi Psychosis in elderly patients: classification and pharmacotherapy
    Jacobo Mintzer
    Medical University of South Carolina, Institute of Psychiatry, Charleston 29406, USA
    J Geriatr Psychiatry Neurol 16:199-206. 2003
    ..The authors review common diagnostics associated with psychosis in the elderly and clinical guidelines to selecting antipsychotic pharmacotherapy...
  8. ncbi What are the challenges faced by psychiatrists in the management of Alzheimer's disease?
    Jacobo E Mintzer
    Medical University of Sourth Carolina, 5900 Core Road, Charleston, SC 29406, USA
    CNS Spectr 9:13-5. 2004
    ....
  9. ncbi Comparison of risperidone and placebo for psychosis and behavioral disturbances associated with dementia: a randomized, double-blind trial. Risperidone Study Group
    I R Katz
    Department of Psychiatry, University of Pennsylvania Medical School, Philadelphia 19104, USA
    J Clin Psychiatry 60:107-15. 1999
    ....
  10. ncbi Underlying mechanisms of psychosis and aggression in patients with Alzheimer's disease
    J E Mintzer
    Department of Psychiatry, Medical University of South Carolina, Charleston, USA
    J Clin Psychiatry 62:23-5. 2001
    ....
  11. ncbi A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil
    Sanford I Finkel
    Department of Psychiatry, University of Chicago Medical School, and the Leonard Schanfield Research Institute at Council for Jewish Elderly, Chicago, IL 60091, USA
    Int J Geriatr Psychiatry 19:9-18. 2004
    ..To examine the safety and efficacy of sertraline augmentation therapy in the treatment of behavioral manifestations of Alzheimer's disease (AD) in outpatients treated with donepezil...
  12. ncbi Apolipoprotein E and gray matter volume loss in patients with mild cognitive impairment and Alzheimer disease
    Maria Vittoria Spampinato
    Department of Radiology, Medical University of South Carolina, 96 Jonathan Lucas St, MSC 323, Charleston, SC, USA
    Radiology 258:843-52. 2011
    ....
  13. ncbi Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors
    Kumar Sambamurti
    Department of Physiology and Neuroscience, and Center on Aging, Medical University of South Carolina, 173 Ashley Avenue, BSB 403, Charleston, SC 29425, USA
    Curr Drug Targets 5:517-28. 2004
    ..The present review summarizes our current understanding of the relationship of AD pathogenesis with cholesterol, lipids and other genetic and environmental risk factors...
  14. ncbi Establishment of a predominantly African-American cohort for the study of Alzheimer's disease: the South Carolina Alzheimer's disease clinical core
    David L Bachman
    Department of Neurosciences, Medical University of South Carolina, Charleston, S C 29425, USA
    Dement Geriatr Cogn Disord 27:329-36. 2009
    ..The recruitment of culturally diverse subject populations into research studies, particularly African-Americans (AA), has been the focus of intense interest by many groups...
  15. ncbi Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future
    Warachal E Faison
    Alzheimer s Research and Clinical Programs, Neurosciences Department, Medical University of South Carolina, Charleston, South Carolina 29406, USA
    Int Psychogeriatr 19:539-58. 2007
    ..for AD to answer two questions: (1) what are the challenges to diagnose and treat AD across different ethnic groups, and (2) are there differences in response to pharmacologic interventions for AD across these different ethnic groups?..
  16. ncbi Assessing current practice in Alzheimer's disease
    Jacobo E Mintzer
    Medical University of Sourth Carolina, Charleston, SC, USA
    CNS Spectr 9:5. 2004
  17. ncbi Quetiapine treatment of psychosis associated with dementia: a double-blind, randomized, placebo-controlled clinical trial
    Pierre N Tariot
    Memory Disorders Center, Banner Alzheimer s Disease Institute, Phoenix, Arizona, USA
    Am J Geriatr Psychiatry 14:767-76. 2006
    ....
  18. ncbi Time for change: the role of nonpharmacological interventions in treating behavior problems in nursing home residents with dementia
    Jiska Cohen-Mansfield
    Department of Health Care Sciences and of Prevention and Community Health, George Washington University Medical Center, Washington, DC, USA
    Alzheimer Dis Assoc Disord 19:37-40. 2005
    ..The paper delineates some of the steps that are needed to move toward a more appropriate treatment of persons with dementia who manifest behavior problems...
  19. ncbi High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial
    Paul S Aisen
    Department of Neurosciences, University of California, San Diego, 9500 Gilman Dr, M C 0949, La Jolla, CA 92093, USA
    JAMA 300:1774-83. 2008
    ..Prior studies of B vitamins to reduce homocysteine in AD have not had sufficient size or duration to assess their effect on cognitive decline...
  20. ncbi Comparison of rapidly acting intramuscular olanzapine, lorazepam, and placebo: a double-blind, randomized study in acutely agitated patients with dementia
    Karena M Meehan
    Lilly Research Laboratories, Eli Lilly and Company, Lilly Corporate Center, Indianapolis, IN 46285, USA
    Neuropsychopharmacology 26:494-504. 2002
    ..Intramuscular injection of olanzapine may therefore provide substantial benefit in rapidly treating inpatients with acute dementia-related agitation...
  21. ncbi Design of Depression in Alzheimer's Disease Study-2
    Barbara K Martin
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Am J Geriatr Psychiatry 14:920-30. 2006
    ....
  22. ncbi The growing, ethnically diverse aging population: is our field advancing with it?
    Warachal E Faison
    Am J Geriatr Psychiatry 13:541-4. 2005
  23. ncbi Clinical application of operationalized criteria for 'Depression of Alzheimer's Disease'
    Paul B Rosenberg
    Division of Geriatric Psychiatry and Neuropsychiatry, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Int J Geriatr Psychiatry 20:119-27. 2005
    ..Criteria for the diagnosis of dAD have been proposed previously...

Research Grants5

  1. Institute for Research Minority Training on Mental Health
    Jacobo Mintzer; Fiscal Year: 2006
    ..We expect this effort to be the incubator for a new generation of minority researchers dedicated to the study of mental health and aging...
  2. Depressoin in Alzheimer's Disease Study-2 (DIADS-2)
    Jacobo Mintzer; Fiscal Year: 2007
    ..abstract_text> ..
  3. Institute for Research Minority Training on Mental Health
    Jacobo Mintzer; Fiscal Year: 2007
    ..We expect this effort to be the incubator for a new generation of minority researchers dedicated to the study mental health and aging. ..
  4. Apathy in Alzheimer's Disease Methylphenidate Trial
    Jacobo Mintzer; Fiscal Year: 2009
    ..This study aims to develop a new treatment for apathy in AD that could decrease its debilitating consequences and reduce patients' dependency on caregivers, providing well-deserved relief to patients and their loved ones. ..
  5. Apathy in Alzheimer's Disease Methylphenidate Trial
    Paul B Rosenberg; Fiscal Year: 2010
    ..This study aims to develop a new treatment for apathy in AD that could decrease its debilitating consequences and reduce patients'dependency on caregivers, providing well-deserved relief to patients and their loved ones. ..