Detail Information
Publications
S-adenosylmethionine but not glutathione protects against galactosamine-induced cytotoxicity in rat hepatocyte culturesJoellyn M McMillan
Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC 29425, USA
Toxicology 222:175-84. 2006....
S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytesJ M McMillan
Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, SC 29425, USA
J Pharm Pharmacol 57:599-605. 2005..5. This low cell accumulation supports the finding of paracellular transport as the only mode of cell membrane transport. Increased hepatocellular protection for SAMe may be accomplished by converting SAMe to a more lipid-soluble prodrug...
