Research Topics
| S P MahadikSummaryAffiliation: Medical College of Georgia Country: USA Publications
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Detail Information
Publications
Oxidative stress and role of antioxidant and omega-3 essential fatty acid supplementation in schizophreniaS P Mahadik
Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, USA
Prog Neuropsychopharmacol Biol Psychiatry 25:463-93. 2001..10. Since the oxidative stress exists at or before the onset of psychosis the use of antioxidants from the very onset of psychosis may reduce the oxidative injury and dramatically improve the outcome of illness...
Protracted effects of chronic oral haloperidol and risperidone on nerve growth factor, cholinergic neurons, and spatial reference learning in ratsA V Terry
Department of Pharmacology and Toxicology, CB 3618, Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912 2300, USA
Neuroscience 150:413-24. 2007....- Negative effects of chronic oral chlorpromazine and olanzapine treatment on the performance of tasks designed to assess spatial learning and working memory in ratsA V Terry
Department of Pharmacology and Toxicology, Medical College of Georgia, Augusta, GA 30912 2300, USA
Neuroscience 156:1005-16. 2008..These animal data indicate that chronic oral treatment with chlorpromazine or olanzapine can impair the performance of tasks designed to assess specific components of cognition that are affected in schizophrenia... - Chronic treatment with first or second generation antipsychotics in rodents: effects on high affinity nicotinic and muscarinic acetylcholine receptors in the brainA V Terry
Department of Pharmacology and Toxicology, Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912 2300, USA
Neuroscience 140:1277-87. 2006.... - Oral haloperidol or risperidone treatment in rats: temporal effects on nerve growth factor receptors, cholinergic neurons, and memory performanceA V Terry
Department of Pharmacology and Toxicology, CB 3618, Medical College of Georgia, 1120 Fifteenth Street, Augusta, GA 30912 2300, USA
Neuroscience 146:1316-32. 2007.... - Red blood cell membrane essential fatty acid metabolism in early psychotic patients following antipsychotic drug treatmentD R Evans
Department of Psychiatry and Health Behavior, Medical College of Georgia, GA, USA
Prostaglandins Leukot Essent Fatty Acids 69:393-9. 2003..These data also support the augmentation of antipsychotic treatment by supplementation with a combination of antioxidants and omega-3 fatty acids... - Chronic exposure to typical or atypical antipsychotics in rodents: temporal effects on central alpha7 nicotinic acetylcholine receptorsA V Terry
Program in Clinical and Experimental Therapeutics, University of Georgia, College of Pharmacy Augusta Campus, Medical College of Georgia, Augusta, GA 30912, USA
Neuroscience 136:519-29. 2005..e. the alpha7 nicotinic receptor), but that the magnitude of the deficits was not sufficient to impair auditory gating... - Differential effects of chronic haloperidol and olanzapine exposure on brain cholinergic markers and spatial learning in ratsA V Terry
Program in Clinical and Experimental Therapeutics, University of Georgia College of Pharmacy (Augusta Campus, Medical College of Georgia, Augusta, GA 30912-2450, USA
Psychopharmacology (Berl) 164:360-8. 2002..CONCLUSIONS: The results in the rat suggest that OLZ (relative to HAL) may be more desirable as an antipsychotic for patients suffering from memory dysfunction especially for those in which cholinergic deficits may already be present... - Antipsychotic drugs differentially modulate apolipoprotein D in rat brainM M Khan
Department of Psychiatry and Health Behavior, Medical College of Georgia, Augusta, GA 30904, USA
J Neurochem 86:1089-100. 2003..The increased expression of apoD by atypical antipsychotics may reflect a novel molecular mechanism underlying their favorable effects compared with HAL on cognition, negative symptoms and extra-pyramidal symptoms in schizophrenia...