Brent Logan

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Finding the maximum safe dose level for heteroscedastic data
    Ajit C Tamhane
    Departments of IE MS and of Statistics, Northwestern University, Evanston, IL 60208, USA
    J Biopharm Stat 14:843-56. 2004
  2. pmc The use of group sequential designs with common competing risks tests
    Brent R Logan
    Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Stat Med 32:899-913. 2013
  3. ncbi request reprint Optimal two-stage randomized phase II clinical trials
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, 53226 0509, USA
    Clin Trials 2:5-12. 2005
  4. ncbi request reprint Pairwise multiple comparison adjustment in survival analysis
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, 53226 0509, USA
    Stat Med 24:2509-23. 2005
  5. pmc Comparing treatments in the presence of crossing survival curves: an application to bone marrow transplantation
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Biometrics 64:733-40. 2008
  6. pmc Analyzing center specific outcomes in hematopoietic cell transplantation
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Lifetime Data Anal 14:389-404. 2008
  7. doi request reprint Superiority inferences on individual endpoints following noninferiority testing in clinical trials
    Brent R Logan
    Division of Biostatistics Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Biom J 50:693-703. 2008
  8. pmc Use of biological assignment in hematopoietic stem cell transplantation clinical trials
    Brent Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA
    Clin Trials 5:607-16. 2008
  9. pmc Marginal models for clustered time-to-event data with competing risks using pseudovalues
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Biometrics 67:1-7. 2011
  10. ncbi request reprint Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease
    Maria Gendelman
    Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Immunol 172:3328-36. 2004

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Finding the maximum safe dose level for heteroscedastic data
    Ajit C Tamhane
    Departments of IE MS and of Statistics, Northwestern University, Evanston, IL 60208, USA
    J Biopharm Stat 14:843-56. 2004
    ..Simulations are performed to study the Type I familywise error rate and power properties of the procedures. A real data example is given to illustrate the procedures...
  2. pmc The use of group sequential designs with common competing risks tests
    Brent R Logan
    Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Stat Med 32:899-913. 2013
    ..A simulation study confirms the theoretical derivations even for modest trial sample sizes. We used two examples of clinical trials in hematopoietic cell transplantation to illustrate the techniques...
  3. ncbi request reprint Optimal two-stage randomized phase II clinical trials
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, 53226 0509, USA
    Clin Trials 2:5-12. 2005
    ..Furthermore, it generally has smaller actual sample size when most of the treatments are effective than using multiple single-arm studies, leading to substantial efficiencies in terms of maximum planned sample size...
  4. ncbi request reprint Pairwise multiple comparison adjustment in survival analysis
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, 53226 0509, USA
    Stat Med 24:2509-23. 2005
    ....
  5. pmc Comparing treatments in the presence of crossing survival curves: an application to bone marrow transplantation
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Biometrics 64:733-40. 2008
    ..We study these methods using simulation and illustrate them on a study comparing survival for autologous and allogeneic bone marrow transplants...
  6. pmc Analyzing center specific outcomes in hematopoietic cell transplantation
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Lifetime Data Anal 14:389-404. 2008
    ..We illustrate the technique using a recent center specific analysis performed by the Center for International Blood and Marrow Transplant Research, and study the performance of this method using simulation...
  7. doi request reprint Superiority inferences on individual endpoints following noninferiority testing in clinical trials
    Brent R Logan
    Division of Biostatistics Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Biom J 50:693-703. 2008
    ..This is verified in a simulation study. Instead, we suggest applying the one-sided likelihood ratio test used by Perlman and Wu (2004) or the union-intersection t(max) test used by Tamhane and Logan (2004)...
  8. pmc Use of biological assignment in hematopoietic stem cell transplantation clinical trials
    Brent Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA
    Clin Trials 5:607-16. 2008
    ..e., chosen according to whether or not the patient had a matched sibling donor...
  9. pmc Marginal models for clustered time-to-event data with competing risks using pseudovalues
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Biometrics 67:1-7. 2011
    ..Simulation studies show that the method works well to adjust the SE for the within-cluster correlation. We illustrate the method on a dataset looking at outcomes after bone marrow transplantation...
  10. ncbi request reprint Host conditioning is a primary determinant in modulating the effect of IL-7 on murine graft-versus-host disease
    Maria Gendelman
    Bone Marrow Transplant Program, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Immunol 172:3328-36. 2004
    ..We conclude that host conditioning modulates the ability of exogenous IL-7 to exacerbate GVHD and that this occurs through induction of endogenous IL-7 production...
  11. ncbi request reprint Analyzing survival curves at a fixed point in time
    John P Klein
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Stat Med 26:4505-19. 2007
    ..The methods are illustrated on a study comparing survival for autologous and allogeneic bone marrow transplants...
  12. ncbi request reprint Expression of p53, c-Myc, or Bcl-6 suggests a poor prognosis in primary central nervous system diffuse large B-cell lymphoma among immunocompetent individuals
    Chung Che Chang
    Department of Pathology, Medical College of Wisconsin, Milwaukee 53226, USA
    Arch Pathol Lab Med 127:208-12. 2003
    ..Primary central nervous system (CNS) diffuse large B-cell lymphoma (DLBCL) in immunocompetent individuals, although rare, has been rising in incidence. Currently, no reliable prognostic markers are available for these individuals...
  13. ncbi request reprint Alpha phenyl-tert-butyl nitrone (PBN) protects syngeneic marrow transplant recipients from the lethal cytokine syndrome occurring after agonistic CD40 antibody administration
    Maria Gendelman
    Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Blood 105:428-31. 2005
    ....
  14. pmc Inference for current leukemia free survival
    Leiyan Liu
    Division of Biostatistics, Department of Population Health Medical College of Wisconsin, 9701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Lifetime Data Anal 14:432-46. 2008
    ..We illustrate these inference methods on a bone marrow transplant dataset...
  15. pmc Homeostatic expansion and repertoire regeneration of donor T cells during graft versus host disease is constrained by the host environment
    Jack Gorski
    Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA
    Blood 109:5502-10. 2007
    ..We thereby conclude that the host environment and not an intrinsic T-cell defect is primarily responsible for the lack of effective T-cell expansion and diversification of complex T-cell repertoires that occurs during GVHD...
  16. doi request reprint Comparison of outcomes after HLA-matched sibling and unrelated donor transplantation for children with high-risk acute lymphoblastic leukemia
    Mei Jie Zhang
    Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Biol Blood Marrow Transplant 18:1204-10. 2012
    ..Our observations support transplantation of BM or cord blood from a suitably matched unrelated donor or cord blood for patients without an HLA-matched sibling with ALL in second CR...
  17. ncbi request reprint An evaluation of spatial thresholding techniques in fMRI analysis
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Hum Brain Mapp 29:1379-89. 2008
    ..Finally, the methods are illustrated with a real bilateral finger-tapping fMRI experiment...
  18. ncbi request reprint Gadolinium attenuates regional stunning in the canine heart in vivo
    Alfred C Nicolosi
    Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, USA
    J Thorac Cardiovasc Surg 124:57-62. 2002
    ..The present study tested the hypothesis that gadolinium would also attenuate regional myocardial stunning in an in vivo model...
  19. ncbi request reprint Effects of gadolinium on regionally stunned myocardium: temporal considerations
    Alfred C Nicolosi
    Department of Surgery Division of Cardiothoracic Surgery, The Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Surg Res 139:286-91. 2007
    ..This study sought to determine whether giving Gd(3+) during ischemia or during reperfusion also ameliorates stunning, as these temporal relationships could help determine the clinical utility of this novel agent...
  20. pmc Reducing the risk for transplantation-related mortality after allogeneic hematopoietic cell transplantation: how much progress has been made?
    John T Horan
    Children s Healthcare of Atlanta at Egleston, Emory University Hospital, Atlanta, GA, USA
    J Clin Oncol 29:805-13. 2011
    ..Transplantation-related mortality (TRM) is a major barrier to the success of allogeneic hematopoietic cell transplantation (HCT)...
  21. ncbi request reprint A complex way to compute fMRI activation
    Daniel B Rowe
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Neuroimage 23:1078-92. 2004
    ..We investigate the performance of the model on a real dataset, then compare the magnitude-only and complex models under varying signal-to-noise ratios in a simulation study with varying activation contrast effects...
  22. pmc Behavior modification and risk perception in patients with nonmelanoma skin cancer
    John S Rhee
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    WMJ 107:62-8. 2008
    ..Nonmelanoma skin cancer (NMSC) is the most common cancer among humans, yet risk perceptions and preventive health behaviors in those who survive this cancer are relatively unknown...
  23. ncbi request reprint Complex fMRI analysis with unrestricted phase is equivalent to a magnitude-only model
    Daniel B Rowe
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 24:603-6. 2005
    ..This suggests that improvements to the magnitude-only model are possible by modeling the phase in each voxel over time...
  24. pmc Peripheral blood grafts from unrelated donors are associated with increased acute and chronic graft-versus-host disease without improved survival
    Mary Eapen
    Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Biol Blood Marrow Transplant 13:1461-8. 2007
    ..The higher rate of cGVHD after PBSC transplants and, consequently, more frequent late adverse events warrant extended follow up of PBSC recipients...
  25. pmc Validation of a quality-of-life instrument for patients with nonmelanoma skin cancer
    John S Rhee
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 W Wisconsin Avenue, Milwaukee, WI 53226, USA
    Arch Facial Plast Surg 8:314-8. 2006
    ..To validate a disease-specific quality-of-life instrument--the Skin Cancer Index--intended to measure quality-of-life issues relevant to patients with nonmelanoma skin cancer...
  26. pmc The skin cancer index: clinical responsiveness and predictors of quality of life
    John S Rhee
    Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Laryngoscope 117:399-405. 2007
    ....
  27. ncbi request reprint Temporal discordance between graft-versus-leukemia and graft-versus-host responses: a strategy for the separation of graft-versus-leukemia/graft-versus-host reactivity?
    Parameswaran Hari
    Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Biol Blood Marrow Transplant 10:743-7. 2004
    ....
  28. ncbi request reprint An evaluation of thresholding techniques in fMRI analysis
    Brent R Logan
    Division of Biostatistics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    Neuroimage 22:95-108. 2004
    ..Therefore, the simple procedures described work well for thresholding most single-subject fMRI experiments and are recommended. The methods are illustrated with a real bilateral finger tapping experiment...
  29. ncbi request reprint Role of the passive apoptotic pathway in graft-versus-host disease
    William R Drobyski
    Department of Medicine and Bone Marrow Transplant Program, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Immunol 169:1626-33. 2002
    ..Moreover, the susceptibility of donor T cells to undergo passive apoptosis is a significant factor in determining GVHD severity under noninflammatory but not inflammatory conditions...
  30. ncbi request reprint Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic leukemia
    Chung Che Chang
    Department of Pathology, Division of Hematology Oncology, and Division of Biostatistics, Medical College of Wisconsin, Milwaukee 53226, USA
    Blood 100:4671-5. 2002
    ..Our results suggest that B-CLL with expression of MUM1/IRF4, indicative of postgerminal center origin, has a more favorable clinical course and that MUM1/IRF4 is an important prognostic marker in B-CLL...
  31. ncbi request reprint Regression models for hazard rates versus cumulative incidence probabilities in hematopoietic cell transplantation data
    Brent R Logan
    Division of Biostatistics and Center for International Blood and Marrow Transplant Research, Medical College of Wisconsin, Milwaukee, USA
    Biol Blood Marrow Transplant 12:107-12. 2006
    ..Finally, we show how these discrepancies occur because 2 different characteristics of the time-to-event distribution are being modeled...
  32. pmc Lifetime probabilities of hematopoietic stem cell transplantation in the U.S
    J J Nietfeld
    Department of Pathology, University Medical Center Utrecht UMCU, Utrecht, The Netherlands
    Biol Blood Marrow Transplant 14:316-22. 2008
    ....
  33. ncbi request reprint Accurate critical constants for the one-sided approximate likelihood ratio test of a normal mean vector when the covariance matrix is estimated
    Ajit C Tamhane
    Department of Statistics, Northwestern University, Evanston, Illinois 60208, USA
    Biometrics 58:650-6. 2002
    ..The proposed approximation is then extended to the heteroscedastic case. The accuracy of both the approximations is verified by simulations. A real data example is given to illustrate the use of the approximations...
  34. doi request reprint On the probability of using cord blood
    J J Nietfeld
    Biol Blood Marrow Transplant 14:724-5. 2008
  35. pmc Impact of cytogenetics on outcome of matched unrelated donor hematopoietic stem cell transplantation for acute myeloid leukemia in first or second complete remission
    Martin S Tallman
    Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Blood 110:409-17. 2007
    ..However, treatment-related mortality was high. Matched unrelated donor HSCT should be considered for all patients with unfavorable cytogenetics who lack a suitable HLA-matched sibling donor...