Research TopicsSpecies | ELLEN LEMOSYSummaryAffiliation: Medical College of Georgia Country: USA Publications
Research Grants
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Detail Information
Publications
Pattern formation: the eggshell holds the cueEllen K LeMosy
Department of Cellular Biology and Anatomy, Medical College of Georgia, 1459 Laney Walker Boulevard, CB2915, Augusta, GE 30901, USA
Curr Biol 13:R508-10. 2003....
Spatially dependent activation of the patterning protease, EasterEllen K LeMosy
Department of Cellular Biology and Anatomy, Medical College of Georgia, 1120 15th St, CB2915, Augusta, GA 30912, USA
FEBS Lett 580:2269-72. 2006..Here, biochemical studies demonstrate that this spatial control occurs at or above the level of Easter zymogen activation, rather than through direct promotion of Easter's catalytic activity against the signaling ligand...
Three-dimensional models of proteases involved in patterning of the Drosophila Embryo. Crucial role of predicted cation binding sitesThierry Rose
Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Biol Chem 278:11320-30. 2003..A mutation in Ea predicted to introduce Na(+) binding results in apparently increased activity with ventralization of the embryo, an effect not observed with wild-type Ea mRNA...
Minor proteins and enzymes of the Drosophila eggshell matrixMazen Fakhouri
Department of Cellular Biology and Anatomy, Medical College of Georgia, 1120 15th St, CB2915, Augusta, GA 30912, USA
Dev Biol 293:127-41. 2006..This work provides a framework for future molecular studies of eggshell assembly...
Proteolytic regulatory mechanisms in the formation of extracellular morphogen gradientsEllen K LeMosy
Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, Georgia 30912, USA
Birth Defects Res C Embryo Today 78:243-55. 2006....
Mutagenesis of the cysteine-rich clip domain in the Drosophila patterning protease, SnakeSufang Tian
Department of Cellular Biology and Anatomy, Medical College of Georgia, 1120 15th Street, CB1101, Augusta, GA 30912, USA
Arch Biochem Biophys 475:169-74. 2008..We discuss implications of these and other results for potential biological roles of the Snake clip domain and for use of the in vitro assay in predicting protease behavior...
Palisade is required in the Drosophila ovary for assembly and function of the protective vitelline membraneMaggie Elalayli
Department of Cellular Biology and Anatomy, Medical College of Georgia, Augusta, GA 30912, USA
Dev Biol 319:359-69. 2008..Our results demonstrate that Palisade is involved in coordinating assembly of the vitelline membrane and is required for functional properties of the eggshell...
Research Grants
- Spatial Control of Proteolysis in Dorsoventral PolarityELLEN LEMOSY; Fiscal Year: 2007....
- Spatial Control of Proteolysis in Dorsoventral PolarityELLEN LEMOSY; Fiscal Year: 2009..abstract_text> ..
