Affiliation: Medical University of South Carolina
- High-osmolarity saline in neurocritical care: systematic review and meta-analysisChristos Lazaridis
Department of Neurosciences, Neurosciences Intensive Care Unit, Medical University of South Carolina, Charleston, SC, USA
Crit Care Med 41:1353-60. 2013..We conducted a systematic literature review on the use of 23.4% saline in neurocritically ill patients and a meta-analysis of the effect of 23.4% saline on intracranial pressure reduction...
- Optimal cerebral perfusion pressure: are we ready for it?Christos Lazaridis
Academic Neurosurgical Unit, University of Cambridge Clinical School, Cambridge, UK
Neurol Res 35:138-48. 2013....
- Liberation of neurosurgical patients from mechanical ventilation and tracheostomy in neurocritical careChristos Lazaridis
Department of Neurosciences Neurosciences Critical Care, Medical University of South Carolina, Charleston, SC 29425, USA
J Crit Care 27:417.e1-8. 2012..Future studies are required to better assess indicators for extubation readiness, evaluate the predictors of extubation failure in brain-injured patients, and define the most appropriate timing for a tracheostomy...
- Cerebral blood flow velocity changes and the value of the pulsatility index post decompressive craniectomyChristos Lazaridis
Neurosciences Intensive Care Unit, Medical University of South Carolina, Charleston, SC 29425, USA
J Clin Neurosci 19:1052-4. 2012..To our knowledge, this is the first report on FV/PI monitoring after SOC. TCD is a readily available, non-invasive test. The PI may provide useful information regarding timing and effectiveness of DC...
- Cerebral blood flow, brain tissue oxygen, and metabolic effects of decompressive craniectomyChristos Lazaridis
Neurosciences Intensive Care Unit, Divisions of Neurology and Neurosurgery, Medical University of South Carolina, 96 Jonathan Lucas Street, Ste 307 CSB, Charleston, SC 29425, USA
Neurocrit Care 16:478-84. 2012..Elucidating the pathophysiology of pressure-flow and cerebral hemodynamic consequences of DC could assist in optimizing clinical decision making and further defining the role of decompressive craniectomy...
- Cerebral fat embolism and the "starfield" pattern: a case reportAmit Aravapalli
Department of Internal Medicine, Medical University of South Carolina, 96 Jonathan Lucas Street, Charleston, SC 29425, USA
Cases J 2:212. 2009..We describe a patient with non-head trauma who demonstrated the classic "starfield" pattern on diffusion-weighted MRI imaging...
- Intra-aortic balloon pump counterpulsation in the setting of subarachnoid hemorrhage, cerebral vasospasm, and neurogenic stress cardiomyopathy. Case report and review of the literatureChristos Lazaridis
Neurosciences Intensive Care Unit, Departments of Neurology and Neurosurgery, Medical University of South Carolina, Charleston, SC 29425, USA
Neurocrit Care 13:101-8. 2010..Vasopressors and inotropes are commonly used to optimize mean arterial pressure (MAP) and cerebral perfusion pressure (CPP). Intra-aortic balloon counterpulsation pump (IABP) may be indicated in the management of these patients...
- Advanced hemodynamic monitoring: principles and practice in neurocritical careChristos Lazaridis
Neurosciences Intensive Care Unit, Department of Neurology, Medical University of South Carolina, Charleston, SC, USA
Neurocrit Care 16:163-9. 2012..A thorough understanding of hemodynamics and of the available monitoring modalities is an essential skill for the neurointensivist...
- Risk factors and medical management of vasospasm after subarachnoid hemorrhageChristos Lazaridis
Department of Neurology, Neurosciences Intensive Care Unit, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 428, Charleston, SC 29425, USA
Neurosurg Clin N Am 21:353-64. 2010....
- Familial nontraumatic, nonaneurysmal subarachnoid hemorrhage: a report on three first-degree siblingsChristos Lazaridis
Department of Neurology, Medical University of South Carolina, Charleston, South Carolina, USA
J Neurosurg 115:621-3. 2011..The identification of families with multiple affected members could lead to an improved understanding of the genetic and environmental factors associated with this condition...
- Osmotherapy: use among neurointensivistsAngela N Hays
Department of Neurosciences, Division of Adult Neurology, Medical University of South Carolina, Charleston, SC, USA
Neurocrit Care 14:222-8. 2011..The authors hypothesized that clinical practice would reflect this heterogeneity with respect to choice of agent, dosing strategy, and methods for monitoring therapy...
- CT perfusion-guided patient selection for endovascular treatment of acute ischemic stroke is safe and effectiveAquilla Turk
Department of Radiology, Medical University of South Carolina, Charleston, South Carolina, USA
J Neurointerv Surg 4:261-5. 2012..The use of CT perfusion (CTP)-based criteria, regardless of time from symptom onset, in patient selection for intra-arterial treatment of ischemic stroke was assessed...
- REACH MUSC: A Telemedicine Facilitated Network for Stroke: Initial Operational ExperienceRobert J Adams
Department of Neurosciences, Medical University of South Carolina Charleston, SC, USA
Front Neurol 3:33. 2012..Despite these challenges, this robust system delivered tPA safely and in a high fraction of patients evaluated using the REACH MUSC system...
- A case of postpartum cerebral angiopathy with subarachnoid hemorrhageYolanda Chik
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA
Nat Rev Neurol 5:512-6. 2009..The headache recurred over the next 10 days, and the patient also developed generalized tonic-clonic seizures. A subarachnoid hemorrhage was demonstrated on a head CT scan...