I M Lang

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Mechanism of UES relaxation initiated by gastric air distension
    Ivan M Lang
    MCW Dysphagia Research Institute, Division of Gastroenterology and Hepatology, and Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin
    Am J Physiol Gastrointest Liver Physiol 307:G452-8. 2014
  2. pmc Digestive and respiratory tract motor responses associated with eructation
    Ivan M Lang
    Dysphagia Animal Institute, Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Gastrointest Liver Physiol 304:G1044-53. 2013
  3. pmc The role of the superior laryngeal nerve in esophageal reflexes
    I M Lang
    MCW Dysphagia Research Institute, Division of Gastroenterology and Hepatology, and Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 302:G1445-57. 2012
  4. pmc Differential activation of medullary vagal nuclei caused by stimulation of different esophageal mechanoreceptors
    Ivan M Lang
    Division of Gastroenterology and Hepatology, MCW Dysphagia Research Laboratory, MFRB 4066, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Brain Res 1368:119-33. 2011
  5. pmc Differential activation of pontomedullary nuclei by acid perfusion of different regions of the esophagus
    Ivan M Lang
    Division of Gastroenterology and Hepatology, MCW Dysphagia Research Laboratory, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Brain Res 1352:94-107. 2010
  6. doi request reprint Brain stem control of the phases of swallowing
    Ivan M Lang
    Department of Medicine, Division of Gastroenterology and Hepatology, Dysphagia Institute Animal Research Laboratory, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Dysphagia 24:333-48. 2009
  7. ncbi request reprint Airway responses to esophageal acidification
    Ivan M Lang
    Medical College of Wisconsin Dysphagia Institute, Divisions of Gastroenterology and Hepatology and Pulmonary Medicine, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Regul Integr Comp Physiol 294:R211-9. 2008
  8. ncbi request reprint Differential activation of medullary vagal nuclei during different phases of swallowing in the cat
    Ivan M Lang
    Department of Medicine, MCW Dysphagia Research Laboratory, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Brain Res 1014:145-63. 2004
  9. ncbi request reprint Mechanisms of airway protection during retching, vomiting, and swallowing
    Ivan M Lang
    MCW Dysphagia Institute, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 283:G529-36. 2002
  10. ncbi request reprint Mechanisms of reflexes induced by esophageal distension
    I M Lang
    Dysphagia Institute and Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 281:G1246-63. 2001

Research Grants

  1. AIRWAY PROTECTION DURING VOMITING
    Ivan Lang; Fiscal Year: 2002

Collaborators

Detail Information

Publications16

  1. pmc Mechanism of UES relaxation initiated by gastric air distension
    Ivan M Lang
    MCW Dysphagia Research Institute, Division of Gastroenterology and Hepatology, and Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin
    Am J Physiol Gastrointest Liver Physiol 307:G452-8. 2014
    ..Therefore, the TUESR caused by gastric air distension is initiated by stimulation of receptors in the esophageal mucosa. ..
  2. pmc Digestive and respiratory tract motor responses associated with eructation
    Ivan M Lang
    Dysphagia Animal Institute, Division of Gastroenterology and Hepatology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Gastrointest Liver Physiol 304:G1044-53. 2013
    ..The phases of eructation can be activated independently of one another or in a different manner to participate in physiological events other than eructation that cause gastroesophageal or esophagogastric reflux...
  3. pmc The role of the superior laryngeal nerve in esophageal reflexes
    I M Lang
    MCW Dysphagia Research Institute, Division of Gastroenterology and Hepatology, and Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 302:G1445-57. 2012
    ..Considering that SLN is not a motor nerve for any of these reflexes, the role of the SLN in control of these reflexes is sensory in nature only...
  4. pmc Differential activation of medullary vagal nuclei caused by stimulation of different esophageal mechanoreceptors
    Ivan M Lang
    Division of Gastroenterology and Hepatology, MCW Dysphagia Research Laboratory, MFRB 4066, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Brain Res 1368:119-33. 2011
    ..The AP may be involved in mediation of belching...
  5. pmc Differential activation of pontomedullary nuclei by acid perfusion of different regions of the esophagus
    Ivan M Lang
    Division of Gastroenterology and Hepatology, MCW Dysphagia Research Laboratory, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Brain Res 1352:94-107. 2010
    ..All responses to esophageal fluid perfusion or acidification are mediated by the vagus nerves...
  6. doi request reprint Brain stem control of the phases of swallowing
    Ivan M Lang
    Department of Medicine, Division of Gastroenterology and Hepatology, Dysphagia Institute Animal Research Laboratory, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Dysphagia 24:333-48. 2009
    ..The ventromedial nucleus of the NTS may govern the coupling of the pharyngeal phase to the esophageal phase of swallowing...
  7. ncbi request reprint Airway responses to esophageal acidification
    Ivan M Lang
    Medical College of Wisconsin Dysphagia Institute, Divisions of Gastroenterology and Hepatology and Pulmonary Medicine, Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Regul Integr Comp Physiol 294:R211-9. 2008
    ..Given the buffering capabilities of mucus, esophageal acidification activates appropriate physiological responses that may act to neutralize gastroesophageal reflux that reaches the larynx, pharynx, or lower airways...
  8. ncbi request reprint Differential activation of medullary vagal nuclei during different phases of swallowing in the cat
    Ivan M Lang
    Department of Medicine, MCW Dysphagia Research Laboratory, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Brain Res 1014:145-63. 2004
    ..The central pattern generator (CPG) for swallowing probably receives significant peripheral feedback, and the NTSvm may participate in the transition of the pharyngeal to the esophageal phase of swallowing...
  9. ncbi request reprint Mechanisms of airway protection during retching, vomiting, and swallowing
    Ivan M Lang
    MCW Dysphagia Institute, Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 283:G529-36. 2002
    ..During swallowing, the airway is protected by laryngeal elevation and glottal closure followed by brief opening of the glottis, which may release subglottal pressure expelling material from the laryngeal vestibule...
  10. ncbi request reprint Mechanisms of reflexes induced by esophageal distension
    I M Lang
    Dysphagia Institute and Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Am J Physiol Gastrointest Liver Physiol 281:G1246-63. 2001
    ..GABA-B receptors also inhibit these reflexes. EUCR and 2P are probably mediated by slowly adapting muscular mechanoreceptors. All six reflexes are mediated by vagal afferent fibers...
  11. ncbi request reprint An overview of the upper esophageal sphincter
    I M Lang
    Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee 53266, USA
    Curr Gastroenterol Rep 2:185-90. 2000
    ..The various muscles of the UES behave differently during its many dynamic states, so that similar functions are accomplished by different muscles...
  12. ncbi request reprint Gastrointestinal motor and myoelectric correlates of motion sickness
    I M Lang
    Department of Medicine and Dysphagia Institute, Medical College of Wisconsin, and Surgical Research Service, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53226, USA
    Am J Physiol 277:G642-52. 1999
    ....
  13. ncbi request reprint Response properties of the brainstem neurons of the cat following intra-esophageal acid-pepsin infusion
    B K Medda
    MCW Dysphagia Institute and Division of Gastroenterology and Hepatology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    Neuroscience 135:1285-94. 2005
    ..Results also indicate that spinal pathway does not contribute to sensitization of brainstem neurons...
  14. pmc AMPA receptor subunits expression and phosphorylation in cingulate cortex in rats following esophageal acid exposure
    B Banerjee
    Division of Gastroenterology and Hepatology, Medical College of Wisconsin, Milwaukee, WI, USA
    Neurogastroenterol Motil 25:973-e776. 2013
    ....
  15. ncbi request reprint Relative contribution of various airway protective mechanisms to prevention of aspiration during swallowing
    Bidyut K Medda
    Medical College of Wisconsin Dysphagia Institute, Division of Gastroenterology and Hepatology, and Department of Medicine, The Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Am J Physiol Gastrointest Liver Physiol 284:G933-9. 2003
    ..Bolus pulsion without laryngeal distraction can open the UES, but at risk of aspiration due to decreased pharyngeal clearance. The epiglottis provides no apparent airway protection during any phase of swallowing...
  16. ncbi request reprint Effects of spontaneous swallows on breathing in awake goats
    Thom R Feroah
    Department of Physiology, Medical College of Wisconsin, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53226, USA
    J Appl Physiol 92:1923-35. 2002
    ..We conclude that, in the awake state, within- and multiple-breath effects on respiratory timing and output are induced and/or required in the coordination of breathing and swallowing...

Research Grants1

  1. AIRWAY PROTECTION DURING VOMITING
    Ivan Lang; Fiscal Year: 2002
    ..Finally, the relative contribution of peripheral reflexes and direct central nervous system control over the motor events that comprise vomiting will be studied. ..