Yonatan M Kupchik

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Biol Psychiatry 71:978-86. 2012
  2. pmc The rostral subcommissural ventral pallidum is a mix of ventral pallidal neurons and neurons from adjacent areas: an electrophysiological study
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC, 29425, USA
    Brain Struct Funct 218:1487-500. 2013
  3. pmc Reinstatement of nicotine seeking is mediated by glutamatergic plasticity
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 110:9124-9. 2013
  4. pmc Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuron 77:867-72. 2013
  5. pmc Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking
    Michael T Stefanik
    Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA
    J Neurosci 33:13654-62. 2013
  6. pmc Rapid, transient synaptic plasticity in addiction
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, BSB 403, Charleston, SC 29425, USA Electronic address
    Neuropharmacology 76:276-86. 2014
  7. pmc Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, Chemical Biology Research Branch, National Institute on Drug Abuse and National Institute on Alcohol and Alcoholism, Rockville, Maryland 20892, Pharmaleads SAS, 75013 Paris, France, and Universite Paris Descartes, 75006 Paris, France
    J Neurosci 34:1057-66. 2014
  8. pmc Optogenetic inhibition of cocaine seeking in rats
    Michael T Stefanik
    Department of Neurosciences, Medical University of South Carolina, Charleston, 29425, USA
    Addict Biol 18:50-3. 2013
  9. pmc α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse
    Sade Spencer
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425
    J Neurosci 34:8605-11. 2014

Collaborators

Detail Information

Publications9

  1. pmc The effect of N-acetylcysteine in the nucleus accumbens on neurotransmission and relapse to cocaine
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Biol Psychiatry 71:978-86. 2012
    ..Here, we examine the effects of NAC applied directly to the NAcore on relapse and neurotransmission in PFC-NAcore synapses, as well as the involvement of the metabotropic glutamate receptors 2/3 (mGluR2/3) and 5 (mGluR5)...
  2. pmc The rostral subcommissural ventral pallidum is a mix of ventral pallidal neurons and neurons from adjacent areas: an electrophysiological study
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC, 29425, USA
    Brain Struct Funct 218:1487-500. 2013
    ..This observation needs to be considered when interpreting past experiments and designing future experiments in the subcommissural VP...
  3. pmc Reinstatement of nicotine seeking is mediated by glutamatergic plasticity
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Proc Natl Acad Sci U S A 110:9124-9. 2013
    ..These results indicate that up-regulated GluN2A, GluN2B, and rapid synaptic potentiation in the accumbens contribute to cue-induced relapse to nicotine use...
  4. pmc Relapse induced by cues predicting cocaine depends on rapid, transient synaptic potentiation
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuron 77:867-72. 2013
    ..The marked cue-induced synaptic changes in the accumbens were correlated with the intensity of cocaine, but not sucrose seeking, and may explain the difficulty addicts experience in managing relapse to cocaine use...
  5. pmc Optogenetic evidence that pallidal projections, not nigral projections, from the nucleus accumbens core are necessary for reinstating cocaine seeking
    Michael T Stefanik
    Department of Neuroscience, Medical University of South Carolina, Charleston, SC, USA
    J Neurosci 33:13654-62. 2013
    ..These data reveal a circuit involving activation of VTA inputs to the NAcore and NAcore projections through the indirect pathway to the dlVP as critical for cocaine-plus-cue-induced reinstatement of cocaine seeking. ..
  6. pmc Rapid, transient synaptic plasticity in addiction
    Cassandra D Gipson
    Department of Neurosciences, Medical University of South Carolina, 173 Ashley Ave, BSB 403, Charleston, SC 29425, USA Electronic address
    Neuropharmacology 76:276-86. 2014
    ..Future directions for relapse prevention and pharmacotherapeutic targeting of the rapid, transient synaptic plasticity in relapse are discussed. This article is part of a Special Issue entitled 'NIDA 40th Anniversary Issue'...
  7. pmc Cocaine dysregulates opioid gating of GABA neurotransmission in the ventral pallidum
    Yonatan M Kupchik
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, Chemical Biology Research Branch, National Institute on Drug Abuse and National Institute on Alcohol and Alcoholism, Rockville, Maryland 20892, Pharmaleads SAS, 75013 Paris, France, and Universite Paris Descartes, 75006 Paris, France
    J Neurosci 34:1057-66. 2014
    ..This may contribute to the difficulties withdrawn addicts experience when trying to resist relapse. ..
  8. pmc Optogenetic inhibition of cocaine seeking in rats
    Michael T Stefanik
    Department of Neurosciences, Medical University of South Carolina, Charleston, 29425, USA
    Addict Biol 18:50-3. 2013
    ..Bilateral optical inhibition of the PL, NAcore or the PL fibers in the NAcore inhibited the reinstatement of cocaine seeking...
  9. pmc α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse
    Sade Spencer
    Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425
    J Neurosci 34:8605-11. 2014
    ..These results also inform ongoing discussion in the literature regarding efficacy of gabapentin as a candidate addiction therapy. ..