Eric L Klett

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Cardiovasc Disord 3:4. 2003
  2. ncbi Genetic defenses against noncholesterol sterols
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, South Carolina 29403, USA
    Curr Opin Lipidol 14:341-5. 2003
  3. ncbi A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, SC 29403, USA
    BMC Med 2:5. 2004
  4. ncbi Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, South Carolina 29403, USA
    BMC Gastroenterol 4:21. 2004
  5. ncbi Biomedicine. Will the real cholesterol transporter please stand up
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, SC 29403, USA
    Science 303:1149-50. 2004
  6. ncbi Liver transplantation in a patient with sitosterolemia and cirrhosis
    Tatu A Miettinen
    Department of Medicine, University of Helsinki, Finland
    Gastroenterology 130:542-7. 2006

Detail Information

Publications6

  1. ncbi The rat STSL locus: characterization, chromosomal assignment, and genetic variations in sitosterolemic hypertensive rats
    Hongwei Yu
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, SC 29403, USA
    BMC Cardiovasc Disord 3:4. 2003
    ..These genes are organized in a head-to-head configuration at the STSL locus on human chromosome 2p21...
  2. ncbi Genetic defenses against noncholesterol sterols
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, South Carolina 29403, USA
    Curr Opin Lipidol 14:341-5. 2003
    ..The newly identified sterolin proteins involved in the absorption and excretion of dietary sterols may fit this bill. If so, we would speculate that a better biomarker may be lurking within their substrate specificities...
  3. ncbi A mouse model of sitosterolemia: absence of Abcg8/sterolin-2 results in failure to secrete biliary cholesterol
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, SC 29403, USA
    BMC Med 2:5. 2004
    ..No phenotypic difference has yet been described in humans with complete defects in either ABCG5 or ABCG8. These proteins, based upon the defects in humans, are responsible for regulating dietary sterol entry and biliary sterol secretion...
  4. ncbi Localization of ABCG5 and ABCG8 proteins in human liver, gall bladder and intestine
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, STR 541, 114 Doughty Street, Charleston, South Carolina 29403, USA
    BMC Gastroenterol 4:21. 2004
    ..Based upon the defects in sitosterolemia, ABCG5 and ABCG8 serve specifically to exclude non-cholesterol sterol entry at the intestinal level and are involved in sterol excretion at the hepatobiliary level...
  5. ncbi Biomedicine. Will the real cholesterol transporter please stand up
    Eric L Klett
    Division of Endocrinology, Diabetes and Medical Genetics, Medical University of South Carolina, Charleston, SC 29403, USA
    Science 303:1149-50. 2004
  6. ncbi Liver transplantation in a patient with sitosterolemia and cirrhosis
    Tatu A Miettinen
    Department of Medicine, University of Helsinki, Finland
    Gastroenterology 130:542-7. 2006
    ..Because the diagnosis of sitosterolemia is based on specialized plasma analyses, we would propose that some consideration to this diagnosis should be given in appropriate cases...