JACK KLEINMAN

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Osteopontin and calcium stone formation
    Jack G Kleinman
    Nephrology Division, Veterans Affairs Medical Center, and Medical College of Wisconsin, Milwaukee 53925, USA
    Nephron Physiol 98:p43-7. 2004
  2. ncbi request reprint Bariatric surgery, hyperoxaluria, and nephrolithiasis: a plea for close postoperative management of risk factors
    J G Kleinman
    Division of Nephrology, Medical College of Wisconsin and VA Medical Center, Milwaukee, Wisconsin 53295, USA
    Kidney Int 72:8-10. 2007
  3. pmc Acidic polyanion poly(acrylic acid) prevents calcium oxalate crystal deposition
    Jack G Kleinman
    Division of Nephrology, Department of Medicine, Medical College of Wisconsin and the Department of Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295, USA
    Kidney Int 74:919-24. 2008
  4. doi request reprint Induction of apoptosis with cisplatin enhances calcium oxalate crystal adherence to inner medullary collecting duct cells
    Jack G Kleinman
    The Medical College of Wisconsin, Milwaukee, WI, USA
    Urol Res 38:97-104. 2010
  5. doi request reprint Telokin expression and the effect of hypoxia on its phosphorylation status in smooth muscle cells from small and large pulmonary arteries
    Jane A Madden
    Department of Neurology, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295, USA
    Am J Physiol Lung Cell Mol Physiol 294:L1166-73. 2008
  6. ncbi request reprint An acidic peptide sequence of nucleolin-related protein can mediate the attachment of calcium oxalate to renal tubule cells
    Elena A Sorokina
    Nephrology Division, Medical College of Wisconsin, Milwaukee, WI, USA
    J Am Soc Nephrol 15:2057-65. 2004
  7. ncbi request reprint Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules
    Jeffrey A Wesson
    Department of Veterans Affairs Medical Center and Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Am Soc Nephrol 14:139-47. 2003

Research Grants

  1. Prevention of Kidney Stone Crystal Retention
    JACK KLEINMAN; Fiscal Year: 2007
  2. RENAL CRYSTAL GROWTH INHIBITOR PROTEINS
    JACK KLEINMAN; Fiscal Year: 2002
  3. Prevention of Kidney Stone Crystal Retention
    Jack G Kleinman; Fiscal Year: 2010

Collaborators

Detail Information

Publications7

  1. ncbi request reprint Osteopontin and calcium stone formation
    Jack G Kleinman
    Nephrology Division, Veterans Affairs Medical Center, and Medical College of Wisconsin, Milwaukee 53925, USA
    Nephron Physiol 98:p43-7. 2004
    ..Finally, preliminary data is presented regarding the amounts and features of OPN present in the urine of stone formers and normal individuals...
  2. ncbi request reprint Bariatric surgery, hyperoxaluria, and nephrolithiasis: a plea for close postoperative management of risk factors
    J G Kleinman
    Division of Nephrology, Medical College of Wisconsin and VA Medical Center, Milwaukee, Wisconsin 53295, USA
    Kidney Int 72:8-10. 2007
    ..After Roux-en-Y, it is important for patients to maintain high urine outputs, to limit fat intake, and to ingest adequate amounts of calcium...
  3. pmc Acidic polyanion poly(acrylic acid) prevents calcium oxalate crystal deposition
    Jack G Kleinman
    Division of Nephrology, Department of Medicine, Medical College of Wisconsin and the Department of Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295, USA
    Kidney Int 74:919-24. 2008
    ..1) had the same effects on crystallization in vitro. Our study shows that acidic polymers hold promise as effective therapies for kidney stones likely through prevention of calcium oxalate crystal aggregate formation...
  4. doi request reprint Induction of apoptosis with cisplatin enhances calcium oxalate crystal adherence to inner medullary collecting duct cells
    Jack G Kleinman
    The Medical College of Wisconsin, Milwaukee, WI, USA
    Urol Res 38:97-104. 2010
    ..We conclude that pre-existing apoptotic injury may promote calcium oxalate crystals attachment to renal tubular epithelium via apical NRP expression...
  5. doi request reprint Telokin expression and the effect of hypoxia on its phosphorylation status in smooth muscle cells from small and large pulmonary arteries
    Jane A Madden
    Department of Neurology, Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin 53295, USA
    Am J Physiol Lung Cell Mol Physiol 294:L1166-73. 2008
    ..These results suggest that in SPA, phosphorylated telokin may help maintain relaxation under unstimulated conditions, whereas in LPA, telokin's function remains undetermined...
  6. ncbi request reprint An acidic peptide sequence of nucleolin-related protein can mediate the attachment of calcium oxalate to renal tubule cells
    Elena A Sorokina
    Nephrology Division, Medical College of Wisconsin, Milwaukee, WI, USA
    J Am Soc Nephrol 15:2057-65. 2004
    ..These results support the notion that surface-associated NRP could mediate attachment of CaOx to the renal tubule epithelium, thereby causing retention of crystals that might eventually become kidney stones...
  7. ncbi request reprint Osteopontin is a critical inhibitor of calcium oxalate crystal formation and retention in renal tubules
    Jeffrey A Wesson
    Department of Veterans Affairs Medical Center and Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    J Am Soc Nephrol 14:139-47. 2003
    ..These data indicate that OPN plays a critical renoprotective role in vivo as an inhibitor of CaOx crystal formation and retention in renal tubules...

Research Grants10

  1. Prevention of Kidney Stone Crystal Retention
    JACK KLEINMAN; Fiscal Year: 2007
    ..Should any of them be suitably free of toxicity, Phase I testing in human would be contemplated, presumably by a licensee. ..
  2. RENAL CRYSTAL GROWTH INHIBITOR PROTEINS
    JACK KLEINMAN; Fiscal Year: 2002
    ....
  3. Prevention of Kidney Stone Crystal Retention
    Jack G Kleinman; Fiscal Year: 2010
    ..Should any of them be suitably free of toxicity, Phase I testing in human would be contemplated, presumably by a licensee. ..