Takashi Kawano

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation
    Takashi Kawano
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Mol Pain 5:12. 2009
  2. pmc Suppressed Ca2+/CaM/CaMKII-dependent K(ATP) channel activity in primary afferent neurons mediates hyperalgesia after axotomy
    Takashi Kawano
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Proc Natl Acad Sci U S A 106:8725-30. 2009
  3. pmc KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy
    Vasiliki Zoga
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Pain 6:6. 2010
  4. pmc Learned avoidance from noxious mechanical simulation but not threshold semmes weinstein filament stimulation after nerve injury in rats
    Hsiang En Wu
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Pain 11:280-6. 2010
  5. pmc Axotomy depletes intracellular calcium stores in primary sensory neurons
    Marcel Rigaud
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Anesthesiology 111:381-92. 2009

Collaborators

Detail Information

Publications5

  1. pmc Nitric oxide activates ATP-sensitive potassium channels in mammalian sensory neurons: action by direct S-nitrosylation
    Takashi Kawano
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Mol Pain 5:12. 2009
    ..NO-dependent mechanisms modulate both KATP channels and participate in the pathophysiology and pharmacology of neuropathic pain. Therefore, we investigated NO modulation of KATP channels in control and axotomized DRG neurons...
  2. pmc Suppressed Ca2+/CaM/CaMKII-dependent K(ATP) channel activity in primary afferent neurons mediates hyperalgesia after axotomy
    Takashi Kawano
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Proc Natl Acad Sci U S A 106:8725-30. 2009
    ..Unitary current conductance and sensitivity of K(ATP) channels to cytosolic ATP and ligands were preserved even after painful nerve injury, thus providing opportunities for selective therapeutic targeting against neuropathic pain...
  3. pmc KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy
    Vasiliki Zoga
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Pain 6:6. 2010
    ....
  4. pmc Learned avoidance from noxious mechanical simulation but not threshold semmes weinstein filament stimulation after nerve injury in rats
    Hsiang En Wu
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Pain 11:280-6. 2010
    ..These findings show that needle stimulation is aversive in rats responding with hyperalgesic behavior. In contrast, SW stimulation, as well as needle stimulation that produced mere withdrawal, is minimally aversive...
  5. pmc Axotomy depletes intracellular calcium stores in primary sensory neurons
    Marcel Rigaud
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Anesthesiology 111:381-92. 2009
    ..The authors examined the effect of injury on intracellular Ca stores of the endoplasmic reticulum, which critically regulate the Ca signal and neuronal function...