Research Topics
| Diane L KamenSummaryAffiliation: Medical University of South Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Vitamin D deficiency in systemic lupus erythematosusDiane L Kamen
Medical University of South Carolina, Charleston, SC, USA
Autoimmun Rev 5:114-7. 2006..9, p<0.01). These results suggest vitamin D deficiency as a possible risk factor for SLE and provide guidance for future studies looking at a potential role of vitamin D in the prevention and/or treatment of SLE...- Antineutrophil cytoplasmic antibody-positive crescentic glomerulonephritis in scleroderma--a different kind of renal crisisDiane L Kamen
Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Rheumatol 33:1886-8. 2006..We suggest that the presence of ANCA be routinely evaluated when faced with renal failure in the setting of SSc... - Vitamin D in lupus - new kid on the block?Diane L Kamen
Medical University of South Carolina College of Medicine, Charleston, South Carolina 29425, USA
Bull NYU Hosp Jt Dis 68:218-22. 2010.... 
Autoantibody prevalence and lupus characteristics in a unique African American populationDiane L Kamen
Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, SC 29425, USA
Arthritis Rheum 58:1237-47. 2008..Because of the unique homogeneous nature of the Gullah, we sought to define the genetic and environmental factors contributing to systemic lupus erythematosus (SLE) in this population...- The link between vitamin D deficiency and systemic lupus erythematosusDiane L Kamen
Division of Rheumatology, Medical University of South Carolina, 96 Jonathan Lucas Street, Suite 912, Charleston, SC 29425, USA
Curr Rheumatol Rep 10:273-80. 2008..More research is needed to understand the role of vitamin D as an immunomodulator and to determine the optimal range of serum 25-hydroxyvitamin D for musculoskeletal, cardiovascular, and immune health... - Skeletal manifestations of systemic autoimmune diseasesDiane L Kamen
Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina, USA
Curr Opin Endocrinol Diabetes Obes 17:540-5. 2010..In this review, we focus on rheumatoid arthritis and systemic lupus erythematosus, two systemic autoimmune diseases in which skeletal manifestations have been well described... - Pulmonary manifestations of systemic lupus erythematosusDiane L Kamen
Medical University of South Carolina, Charleston, SC 29425, USA
Clin Chest Med 31:479-88. 2010..Finding the true prevalence of lung involvement with SLE is complicated by the high rates of pulmonary infections. This article reviews the diverse clinical symptoms and immunologic pulmonary manifestations of SLE... - Bone geometry profiles in women with and without SLEJimmy D Alele
Division of Endocrinology, Diabetes and Medical Genetics, Charleston, SC, USA
J Bone Miner Res 26:2719-26. 2011..There were significant bone geometry differences between SLE and control women at all hip subregions. Bone geometry profiles among SLE women were suggestive of increased fragility... 
Ethnic disparities among patients with systemic lupus erythematosus in South CarolinaErica Anderson
Division of Rheumatology and Immunology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Rheumatol 35:819-25. 2008..To evaluate whether ethnic disparities in mortality exist among hospitalized patients with systemic lupus erythematosus (SLE) in South Carolina, USA...- The importance of inflammation and vitamin D status in SLE-associated osteoporosisJimmy D Alele
Division of Endocrinology, Medical University of South Carolina, Charleston, South Carolina, United States
Autoimmun Rev 9:137-9. 2010..Inadequate vitamin D status can compound the problem of low BMD, leading to increased bone fragility among SLE patients... - Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosusHenda Bouali
Department of Medicine, Division of Rheumatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Rheumatol 34:2028-34. 2007..We hypothesized that the G-463A MPO SNP is a risk factor for developing lupus nephritis (LN) due to its potential influence on the inflammatory response... - Premature atherosclerosis is associated with hypovitaminosis D and angiotensin-converting enzyme inhibitor non-use in lupus patientsRoneka L Ravenell
Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
Am J Med Sci 344:268-73. 2012..These findings provide strong rationale for the study of ACE inhibitors and vitamin D replenishment as preventive therapies in this high-risk population... - A GA microsatellite in the Fli1 promoter modulates gene expression and is associated with systemic lupus erythematosus patients without nephritisErin E Morris
Division of Rheumatology, Department of Medicine, Medical University of South Carolina, 96 Jonathon Lucas St, Charleston, SC 29425, USA
Arthritis Res Ther 12:R212. 2010.... - Vitamin D and molecular actions on the immune system: modulation of innate and autoimmunityDiane L Kamen
Division of Rheumatology, Department of Medicine, Medical University of South Carolina, Charleston, SC, USA
J Mol Med (Berl) 88:441-50. 2010..The purpose of this manuscript is to review the molecular and clinical evidence for vitamin D as a modulator of the innate and adaptive immune system... - Toll-like receptor triggering of a vitamin D-mediated human antimicrobial responsePhilip T Liu
Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, CA 90095, USA
Science 311:1770-3. 2006..These data support a link between TLRs and vitamin D-mediated innate immunity and suggest that differences in ability of human populations to produce vitamin D may contribute to susceptibility to microbial infection...
Research Grants
- The Role of Vitamin D in Systemic Lupus ErythematosusDiane Kamen; Fiscal Year: 2007..Kamen's career as an independent academic clinical investigator with a focus on SLE and patient-oriented research. ..