Ming T Jiang

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure
    Ming Tao Jiang
    Department of Physiology, University of Wisconsin Medical School, Madison, Wis 53706, USA
    Circ Res 91:1015-22. 2002
  2. ncbi request reprint Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro
    Ming Tao Jiang
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 290:H1770-6. 2006
  3. ncbi request reprint Anesthetic preconditioning enhances Ca2+ handling and mechanical and metabolic function elicited by Na+-Ca2+ exchange inhibition in isolated hearts
    Jianzhong An
    Department of Anesthesiology, Medical College of Wisconsin, Wisconsin 53226, USA
    Anesthesiology 105:541-9. 2006
  4. ncbi request reprint Mitochondrial big conductance KCa channel and cardioprotection in infant rabbit heart
    Yang Shi
    Surgery Division of Pediatric Surgery, Medical College of Wisconsin, Mikwaukee, WI 53226, USA
    J Cardiovasc Pharmacol 50:497-502. 2007
  5. ncbi request reprint Isoflurane activates human cardiac mitochondrial adenosine triphosphate-sensitive K+ channels reconstituted in lipid bilayers
    Ming T Jiang
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Anesth Analg 105:926-32, table of contents. 2007
  6. ncbi request reprint Increasing heart size and age attenuate anesthetic preconditioning in guinea pig isolated hearts
    Matthias L Riess
    Department of Anesthesiology and Physiology, Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Anesth Analg 101:1572-6. 2005
  7. ncbi request reprint Isoflurane activates rat mitochondrial ATP-sensitive K+ channels reconstituted in lipid bilayers
    Yuri Nakae
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 284:H1865-71. 2003
  8. ncbi request reprint Cardiac mitochondrial ATP-sensitive potassium channel is activated by nitric oxide in vitro
    Marko Ljubkovic
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    FEBS Lett 581:4255-9. 2007
  9. ncbi request reprint Myocardial protection by isoflurane preconditioning preserves Ca2+ cycling proteins independent of sarcolemmal and mitochondrial KATP channels
    Jianzhong An
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesth Analg 105:1207-13, table of contents. 2007
  10. ncbi request reprint Cardiac mitochondrial preconditioning by Big Ca2+-sensitive K+ channel opening requires superoxide radical generation
    David F Stowe
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 290:H434-40. 2006

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Abnormal Ca2+ release, but normal ryanodine receptors, in canine and human heart failure
    Ming Tao Jiang
    Department of Physiology, University of Wisconsin Medical School, Madison, Wis 53706, USA
    Circ Res 91:1015-22. 2002
    ..These results support a role for SR in the pathogenesis of HF, with abnormal Ca2+ uptake, more than Ca2+ release, contributing to the depressed and slow Ca2+ transient characteristic of HF...
  2. ncbi request reprint Characterization of human cardiac mitochondrial ATP-sensitive potassium channel and its regulation by phorbol ester in vitro
    Ming Tao Jiang
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 290:H1770-6. 2006
    ..This local PKC control mechanism may represent an alternative pathway to that proposed previously for cytosolic PKC during ischemic/pharmacological preconditioning...
  3. ncbi request reprint Anesthetic preconditioning enhances Ca2+ handling and mechanical and metabolic function elicited by Na+-Ca2+ exchange inhibition in isolated hearts
    Jianzhong An
    Department of Anesthesiology, Medical College of Wisconsin, Wisconsin 53226, USA
    Anesthesiology 105:541-9. 2006
    ..Studies also show the benefit of Na+-Ca2+ exchange inhibition on ischemia-reperfusion injury. The authors tested whether APC plus Na+-Ca2+ exchange inhibitors given just on reperfusion affords additive protection in intact hearts...
  4. ncbi request reprint Mitochondrial big conductance KCa channel and cardioprotection in infant rabbit heart
    Yang Shi
    Surgery Division of Pediatric Surgery, Medical College of Wisconsin, Mikwaukee, WI 53226, USA
    J Cardiovasc Pharmacol 50:497-502. 2007
    ..Paxilline did not affect normoxic or hypoxic hearts. Activation of mitoBKCa protects normoxic infant rabbit hearts; however, cardioprotection by chronic hypoxia in infant rabbits does not appear involve mitoBKCa...
  5. ncbi request reprint Isoflurane activates human cardiac mitochondrial adenosine triphosphate-sensitive K+ channels reconstituted in lipid bilayers
    Ming T Jiang
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Anesth Analg 105:926-32, table of contents. 2007
    ..In this study, we examined the direct effect of isoflurane and ROS on human cardiac mitoK(ATP) channels reconstituted into the lipid bilayers...
  6. ncbi request reprint Increasing heart size and age attenuate anesthetic preconditioning in guinea pig isolated hearts
    Matthias L Riess
    Department of Anesthesiology and Physiology, Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Anesth Analg 101:1572-6. 2005
    ..Thus, increasing age and heart size attenuate the susceptibility for APC even in younger guinea pigs. This may have important implications for further basic science research and the possible clinical applicability of APC in humans...
  7. ncbi request reprint Isoflurane activates rat mitochondrial ATP-sensitive K+ channels reconstituted in lipid bilayers
    Yuri Nakae
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 284:H1865-71. 2003
    ..8 mM (P < 0.05, n = 5 approximately 8). We conclude that direct activation of the mitoK(ATP) channel by isoflurane is likely to contribute to volatile anesthetic-induced myocardial preconditioning...
  8. ncbi request reprint Cardiac mitochondrial ATP-sensitive potassium channel is activated by nitric oxide in vitro
    Marko Ljubkovic
    Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    FEBS Lett 581:4255-9. 2007
    ..This activation was inhibited by mitoK(ATP) blockers 5-hydroxydecanoate or glibenclamide. Our observations confirm that NO can directly activate the cardiac mitoK(ATP), which may underlie its contribution to myocardial preconditioning...
  9. ncbi request reprint Myocardial protection by isoflurane preconditioning preserves Ca2+ cycling proteins independent of sarcolemmal and mitochondrial KATP channels
    Jianzhong An
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesth Analg 105:1207-13, table of contents. 2007
    ..Mitochondrial and sarcolemmal K(ATP) channel openings have been implicated in APC-induced cardioprotection. In this study, we investigated the effect of APC on major calcium cycling proteins and its relation to K(ATP) channels...
  10. ncbi request reprint Cardiac mitochondrial preconditioning by Big Ca2+-sensitive K+ channel opening requires superoxide radical generation
    David F Stowe
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Am J Physiol Heart Circ Physiol 290:H434-40. 2006
    ..Thus NS may induce mitochondrial ROS release to initiate preconditioning...
  11. ncbi request reprint Anesthetic preconditioning: the role of free radicals in sevoflurane-induced attenuation of mitochondrial electron transport in Guinea pig isolated hearts
    Matthias L Riess
    Anesthesiology Research Laboratories, Department of Anesthesiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    Anesth Analg 100:46-53. 2005
    ..This may lead to a positive feedback mechanism with augmented ROS generation to trigger APC secondary to altered mitochondrial function...
  12. ncbi request reprint Characteristics and actions of NAD(P)H oxidase on the sarcoplasmic reticulum of coronary artery smooth muscle
    Xiu Yu Yi
    Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, USA
    Am J Physiol Heart Circ Physiol 290:H1136-44. 2006
    ..These results suggest that a local NAD(P)H oxidase system on SR from CASM regulates RyR/Ca2+ channel activity and Ca2+ release from SR by producing O2-*...
  13. ncbi request reprint Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure
    Bailong Xiao
    Cardiovascular Research Group, Department of Physiology and Biophysics, University of Calgary, Calgary, AB, Canada
    Circ Res 96:847-55. 2005
    ..Together, our data indicate that serine-2030 is a major PKA phosphorylation site in RyR2 responding to acute beta-adrenergic stimulation, and that RyR2 is not hyperphosphorylated by PKA in canine HF...