J S Hyde

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Cortical plasticity induced by different degrees of peripheral nerve injuries: a rat functional magnetic resonance imaging study under 9.4 Tesla
    Rupeng Li
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Brachial Plex Peripher Nerve Inj 8:4. 2013
  2. pmc Cross-correlation: an fMRI signal-processing strategy
    James S Hyde
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 62:848-51. 2012
  3. ncbi request reprint High-resolution fMRI using multislice partial k-space GR-EPI with cubic voxels
    J S Hyde
    Biophysics Research Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Magn Reson Med 46:114-25. 2001
  4. pmc W-band frequency-swept EPR
    James S Hyde
    National Biomedical EPR Center, Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Magn Reson 205:93-101. 2010
  5. ncbi request reprint Microwave frequency modulation in CW EPR at W-band using a loop-gap resonator
    James S Hyde
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226 0509, USA
    J Magn Reson 185:259-63. 2007
  6. pmc Spin-label oximetry at Q- and W-band
    W K Subczynski
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA
    J Magn Reson 209:142-8. 2011
  7. ncbi request reprint Molecular organization and dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine bilayers containing a transmembrane alpha-helical peptide
    W K Subczynski
    Biophysics Department, Institute of Molecular Biology, Jagiellonian University, Al Mickiewicza 3, 31 120 Krakow, Poland
    Biochemistry 37:3156-64. 1998
  8. ncbi request reprint Localization of the cortical response to smiling using new imaging paradigms with functional magnetic resonance imaging
    A K Gosain
    Department of Plastic and Reconstructive Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
    Plast Reconstr Surg 108:1136-44. 2001
  9. ncbi request reprint Simultaneous gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle
    K M Donahue
    Biophysics Research Institute, and Department of Medicine, Medical College of Wisconsin, Milwaukee 53226, USA
    J Magn Reson Imaging 8:1106-13. 1998
  10. ncbi request reprint Comparison of simultaneously measured perfusion and BOLD signal increases during brain activation with T(1)-based tissue identification
    W M Luh
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Magn Reson Med 44:137-43. 2000

Research Grants

Collaborators

Detail Information

Publications31

  1. pmc Cortical plasticity induced by different degrees of peripheral nerve injuries: a rat functional magnetic resonance imaging study under 9.4 Tesla
    Rupeng Li
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Brachial Plex Peripher Nerve Inj 8:4. 2013
    ..Likewise, these injuries have been shown to instigate long-lasting central cortical reorganization...
  2. pmc Cross-correlation: an fMRI signal-processing strategy
    James S Hyde
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 62:848-51. 2012
    ..1995. Magn. Reson. Med. 34:537-541). In this method, a whole volume time course of images is collected while the brain is nominally at rest and connectivity is studied by cross-correlation of pixel time courses...
  3. ncbi request reprint High-resolution fMRI using multislice partial k-space GR-EPI with cubic voxels
    J S Hyde
    Biophysics Research Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Magn Reson Med 46:114-25. 2001
    ..Robust fMRI data were obtained across all subjects using 1 x 1 x 1 mm(3) cubic voxels with 10 contiguous slices, although 1.5 x 1.5 x 1.5 mm(3) was found to be optimum. Magn Reson Med 46:114-125, 2001...
  4. pmc W-band frequency-swept EPR
    James S Hyde
    National Biomedical EPR Center, Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Magn Reson 205:93-101. 2010
    ..The paper discusses technical advances required to reach this goal. The hypothesis that trapezoidal frequency sweep is an enabling technology for FT EPR is supported by this study...
  5. ncbi request reprint Microwave frequency modulation in CW EPR at W-band using a loop-gap resonator
    James S Hyde
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226 0509, USA
    J Magn Reson 185:259-63. 2007
    ..3 G at one W incident power, and the frequency deviation was 11.3 MHz p-p, which is equivalent to a field modulation amplitude of 4 G. W-band EPR using an LGR is a favorable configuration for microwave FM experiments...
  6. pmc Spin-label oximetry at Q- and W-band
    W K Subczynski
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI, USA
    J Magn Reson 209:142-8. 2011
    ..These benefits, together with other factors such as a higher resonator efficiency parameter and a new technique for canceling free induction decay signals, are discussed...
  7. ncbi request reprint Molecular organization and dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine bilayers containing a transmembrane alpha-helical peptide
    W K Subczynski
    Biophysics Department, Institute of Molecular Biology, Jagiellonian University, Al Mickiewicza 3, 31 120 Krakow, Poland
    Biochemistry 37:3156-64. 1998
    ..It is concluded that L24 is highly miscible in POPC membranes even at high concentrations in the membrane...
  8. ncbi request reprint Localization of the cortical response to smiling using new imaging paradigms with functional magnetic resonance imaging
    A K Gosain
    Department of Plastic and Reconstructive Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
    Plast Reconstr Surg 108:1136-44. 2001
    ..When combined with biofeedback therapy, this technique may help to improve the outcome of facial reanimation procedures in the future...
  9. ncbi request reprint Simultaneous gradient-echo/spin-echo EPI of graded ischemia in human skeletal muscle
    K M Donahue
    Biophysics Research Institute, and Department of Medicine, Medical College of Wisconsin, Milwaukee 53226, USA
    J Magn Reson Imaging 8:1106-13. 1998
    ....
  10. ncbi request reprint Comparison of simultaneously measured perfusion and BOLD signal increases during brain activation with T(1)-based tissue identification
    W M Luh
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Magn Reson Med 44:137-43. 2000
    ..Perfusion activation maps will likely represent the sites of neuronal activity better than do BOLD activation maps. Magn Reson Med 44:137-143, 2000...
  11. pmc Hyperbolic-cosine waveguide tapers and oversize rectangular waveguide for reduced broadband insertion loss in W-band electron paramagnetic resonance spectroscopy
    R R Mett
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 0509, USA
    Rev Sci Instrum 82:074704. 2011
    ..Minimum return loss was about 30 dB. This paper provides a foundation for further optimization, if needed. Methods are not specific to EPR or the microwave frequency band...
  12. ncbi request reprint Single-shot magnetic field mapping embedded in echo-planar time-course imaging
    Vinai Roopchansingh
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226 0509, USA
    Magn Reson Med 50:839-43. 2003
    ..Values ranged from 0.035 to 0.165 parts per million (ppm)...
  13. pmc Saturation recovery EPR and ELDOR at W-band for spin labels
    Wojciech Froncisz
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, P O Box 26509, Milwaukee, WI 53226 0509, USA
    J Magn Reson 193:297-304. 2008
    ..K. Subczynski, T.G. Camenisch, J.J. Ratke, W. Froncisz, Spin label EPR T(1) values using saturation recovery from 2 to 35 GHz. J. Phys. Chem. B 108 (2004) 9524-9529]. The values of T(1e) decrease at 94 GHz relative to values at 35 GHz...
  14. ncbi request reprint Molecular dynamics of 1-palmitoyl-2-oleoylphosphatidylcholine membranes containing transmembrane alpha-helical peptides with alternating leucine and alanine residues
    Witold K Subczynski
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Biochemistry 42:3939-48. 2003
    ..This explanation was confirmed by calculating the orientational order of leucine side chains in (LA)(12) and L(24) from molecular dynamics simulation studies...
  15. pmc Three-dimensional dynamic structure of the liquid-ordered domain in lipid membranes as examined by pulse-EPR oxygen probing
    Witold K Subczynski
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Biophys J 92:1573-84. 2007
    ..Third, the transmembrane OTP profile in the liquid-ordered domain that contained 50 mol % cholesterol dramatically differed from that which contained 27 mol % cholesterol...
  16. ncbi request reprint Digit tapping model of functional activation in the rat somatosensory cortex
    Marie L Schulte
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, USA
    J Neurosci Methods 157:48-53. 2006
    ....
  17. ncbi request reprint Concentration by centrifugation for gas exchange EPR oximetry measurements with loop-gap resonators
    Witold K Subczynski
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    J Magn Reson 176:244-8. 2005
    ..Typically, the SNR was improved by a factor of five to eight. Oxygen accessibility applications in site-directed spin labeling studies are discussed...
  18. ncbi request reprint Multishot partial-k-space EPI for high-resolution fMRI demonstrated in a rat whisker barrel stimulation model at 3T
    Hanbing Lu
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Magn Reson Med 50:1215-22. 2003
    ..Most of the pixels that exhibited high BOLD responses had high blood volume weightings. The benefits of this technique are expected to increase for high-resolution fMRI at higher magnetic fields, where T(2) (*) is shorter...
  19. pmc Multiquantum EPR spectroscopy of spin-labeled arrestin K267C at 35 GHz
    Candice S Klug
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Biophys J 88:3641-7. 2005
    ..Feasibility has been established for the use of this technique for site-directed spin-labeling studies of biologically relevant samples, particularly the study of protein structure and dynamics...
  20. ncbi request reprint Aqueous flat-cells perpendicular to the electric field for use in electron paramagnetic resonance spectroscopy, II: design
    Jason W Sidabras
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226 0509, USA
    J Magn Reson 172:333-41. 2005
    ..These signal enhancements are predicted with sample holders fabricated from polytetrafluoroethylene. Additional improvement in EPR signal of up to 75% can be achieved by using sample holder materials with lower dielectric constants...
  21. ncbi request reprint Aqueous flat cells perpendicular to the electric field for use in electron paramagnetic resonance spectroscopy
    Richard R Mett
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226 0509, USA
    J Magn Reson 165:137-52. 2003
    ..Rectangular UF modes have an RF magnetic field magnitude that is uniform in a plane. Based on this analysis, a practical multiple flat-cell design is proposed...
  22. ncbi request reprint Momentum-weighted conjugate gradient descent algorithm for gradient coil optimization
    Hanbing Lu
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Magn Reson Med 51:158-64. 2004
    ..The benefits of this design include improved gradient field uniformity and efficiency, with a shorter length than gradient coil designs using coaxial return paths...
  23. ncbi request reprint Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression
    Hanbing Lu
    Department of Biophysics, Medical College of Wisconsin, Milwaukee 53226, USA
    Magn Reson Med 52:1060-8. 2004
    ..We conclude that neuronal activity can be inferred from CBV fMRI data with high spatial accuracy. The data indicate that both intracolumn functional connectivity and neurovascular coupling can be studied using CBV fMRI...
  24. pmc Resting-state functional connectivity of the rat brain
    Christopher P Pawela
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Magn Reson Med 59:1021-9. 2008
    ..Consistent results in two different rat-brain systems, the sensorimotor and visual, strongly support the hypothesis that resting-state BOLD fluctuations are conserved across mammalian species and can be used to map brain systems...
  25. pmc Modeling of region-specific fMRI BOLD neurovascular response functions in rat brain reveals residual differences that correlate with the differences in regional evoked potentials
    Christopher P Pawela
    Department of Biophysics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Neuroimage 41:525-34. 2008
    ..This is the first report that regional differences in neuronal activation to the same stimulus lead to differential BOLD activation...
  26. pmc High spatial resolution increases the specificity of block-design BOLD fMRI studies of overt vowel production
    David A Soltysik
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Neuroimage 41:389-97. 2008
    ....
  27. ncbi request reprint Multipurpose EPR loop-gap resonator and cylindrical TE011 cavity for aqueous samples at 94 GHz
    Jason W Sidabras
    Biophysics Research Institute, Medical College of Wisconsin, Milwaukee, WI 53226 0509, USA
    Rev Sci Instrum 78:034701. 2007
    ....
  28. ncbi request reprint Temporal evolution of the CBV-fMRI signal to rat whisker stimulation of variable duration and intensity: a linearity analysis
    Hanbing Lu
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, 53226, USA
    Neuroimage 26:432-40. 2005
    ..However, significant deviations exist when the stimulus duration is manipulated, particularly in the trailing edge of the CBV-fMRI response curves...
  29. ncbi request reprint Water diffusion heterogeneity index in the human brain is insensitive to the orientation of applied magnetic field gradients
    Kevin M Bennett
    Department of Biophysics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Magn Reson Med 56:235-9. 2006
    ..It is proposed that in clinical use, maps of alpha can be created using diffusion-weighting gradients applied in a single direction that reflect the tissue heterogeneity...
  30. ncbi request reprint Measurements of tissue T1 spin-lattice relaxation time and discrimination of large draining veins using transient EPI data sets in BOLD-weighted fMRI acquisitions
    Yousef Mazaheri
    Department of Medical Physics and Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Neuroimage 32:603-15. 2006
    ..9. The results indicate that transient data sets can provide additional information that is useful for both localization and characterization of the functionally relevant BOLD response...
  31. ncbi request reprint Cerebral cortical representation of external anal sphincter contraction: effect of effort
    Mark K Kern
    Medical College of Wisconsin Digestive DIsease Center, Division of Gastroenterology and Hepatology, Milwaukee, WI 53226, USA
    Am J Physiol Gastrointest Liver Physiol 286:G304-11. 2004
    ..Willful contraction of the EAS is associated with multifocal cerebral cortical activity. The volume and intensity of cerebral cortical activation is commensurate with the level of contractile effort...

Research Grants64

  1. fMRI Technology and Analysis
    James S Hyde; Fiscal Year: 2010
    ..In addition, the work proposed here is expected to contribute fundamentally to knowledge of brain plasticity following nerve injury. 2. ..
  2. Real-Time Motion Correction and Increased Scan-Session Sucess in Clinical MRI
    James S Hyde; Fiscal Year: 2010
    ..There are many more. ..
  3. BROADBAND EPR SPECTROMETER WITH DIGITAL SUBSAMPLING
    James Hyde; Fiscal Year: 2003
    ..It is the only method that can detect the formation of free radicals in biology unambiguously. It contributes to health-related research at the basic fundamental level. ..
  4. DEVELOPMENT OF BIOMEDICAL ESR INSTRUMENTATION
    James Hyde; Fiscal Year: 2003
    ..The investigator asserts that only on such a foundation can a rational approach to improved human health be based. ..
  5. CORE--SUBJECT INTERFACE SYSTEMS
    James Hyde; Fiscal Year: 2002
    ..abstract_text> ..
  6. 3T Whole-Body MRI Scanner for Functional Imaging
    James Hyde; Fiscal Year: 2003
    ..It will have no clinical fee-for-service usage. The fMRI group at MCW is superbly positioned to provide leadership at a national level in the use of fMRI in medicine. ..
  7. EPR Sample-cell-Resonator Design and Construction
    James Hyde; Fiscal Year: 2007
    ..Work proposed here will improve the quality of data obtained in these experiments. ..
  8. HFSS Modeling in Aqueous Biological Samples for EPR
    James Hyde; Fiscal Year: 2007
    ..An additional benefit is provided by Uniform Field resonators. Because the microwave field is uniform over the sample, all portions respond in the same way, which improves the data quality. ..
  9. Development of Biomedical EPR Instrumentation
    James Hyde; Fiscal Year: 2007
    ..Information on protein and membrane dynamics can be obtained on a time scale that is believed not only to be inaccessible using other modalities, but also to be of high biological relevance. ..
  10. fMRI Technology and Analysis
    James Hyde; Fiscal Year: 2007
    ..Contributions to the underlying technological base of fMRI methodology will be of increasing significance for improved health care in future years as the methods enter clinical practice. ..
  11. Development of an fMRI Brain Plasticity Model in Rats Following Nerve Transfer
    James Hyde; Fiscal Year: 2006
    ..The proposed research has significant opportunity to enhance knowledge and could well serve as the basis of a research career in medicine. ..
  12. LOOP-GAP RESONATOR COILS FOR MRI AND 31-P SPECTROSCOPY
    James Hyde; Fiscal Year: 1993
    ..Applications focus on tissue grafts and possible rejection including kidneys, heart and skin...
  13. DEVELOPMENT OF BIOMEDICAL ESR INSTRUMENTATION
    James Hyde; Fiscal Year: 1999
    ..Instrumental development proposed here can contribute to instrumental design in other fields of spectroscopy including spin-echo EPR and high-resolution NMR. ..
  14. BIOMEDICAL ESR SPECTROSCOPY CENTER
    James Hyde; Fiscal Year: 1980
    ....
  15. DEVELOPMENT OF BIOMEDICAL ESR INSTRUMENTATION
    James Hyde; Fiscal Year: 1993
    ..The costs of the units are relatively modest, and the designs will be readily transportable to other laboratories, which should increase the overall use of ESR saturation-recovery methodology...
  16. DEVELOPMENT OF BIOMEDICAL ESR INSTRUMENTATION
    James Hyde; Fiscal Year: 1991
    ..ESR is a widely used basic spectroscopic technique that results in more than 2000 scientific papers per year, with about half in the life sciences over a wide variety of subjects...
  17. LOOP GAP RESONATOR COILS FOR MRI AND 31P SPECTROSCOPY
    James Hyde; Fiscal Year: 2003
    ..The research proposed here is in support of these four streams of fMRI research. ..