Matthew R Hodges

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Fluoxetine augments ventilatory CO2 sensitivity in Brown Norway but not Sprague Dawley rats
    Matthew R Hodges
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States
    Respir Physiol Neurobiol 186:221-8. 2013
  2. doi request reprint Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice
    Matthew R Hodges
    Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, United States
    Respir Physiol Neurobiol 177:133-40. 2011
  3. pmc The role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulation
    Matthew R Hodges
    BSB 504, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Appl Physiol (1985) 108:1425-32. 2010
  4. doi request reprint Medullary serotonin neurons and their roles in central respiratory chemoreception
    Matthew R Hodges
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 173:256-63. 2010
  5. pmc Changes in neurochemicals within the ventrolateral medullary respiratory column in awake goats after carotid body denervation
    Justin Robert Miller
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin
    J Appl Physiol (1985) 115:1088-98. 2013
  6. pmc Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons
    Matthew R Hodges
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, United States
    Respir Physiol Neurobiol 164:350-7. 2008
  7. pmc Atropine microdialysis within or near the pre-Botzinger Complex increases breathing frequency more during wakefulness than during NREM sleep
    Clarissa Muere
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Appl Physiol (1985) 114:694-704. 2013
  8. pmc Acute and chronic effects of carotid body denervation on ventilation and chemoreflexes in three rat strains
    Gary C Mouradian
    Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Physiol 590:3335-47. 2012
  9. pmc Changes in glutamate receptor subunits within the medulla in goats after section of the carotid sinus nerves
    Justin Robert Miller
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin
    J Appl Physiol (1985) 116:1531-42. 2014
  10. pmc Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development
    Matthew R Hodges
    Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA
    J Neurosci 29:10341-9. 2009

Collaborators

Detail Information

Publications14

  1. pmc Fluoxetine augments ventilatory CO2 sensitivity in Brown Norway but not Sprague Dawley rats
    Matthew R Hodges
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, United States
    Respir Physiol Neurobiol 186:221-8. 2013
    ..Thus, fluoxetine increases ventilatory CO2 sensitivity in BN but not SD rats, further suggesting altered 5-HT system function may contribute to the inherently low CO2 sensitivity in the BN rat...
  2. doi request reprint Altered ventilatory and thermoregulatory control in male and female adult Pet-1 null mice
    Matthew R Hodges
    Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06520, United States
    Respir Physiol Neurobiol 177:133-40. 2011
    ....
  3. pmc The role of medullary serotonin (5-HT) neurons in respiratory control: contributions to eupneic ventilation, CO2 chemoreception, and thermoregulation
    Matthew R Hodges
    BSB 504, Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI 53226, USA
    J Appl Physiol (1985) 108:1425-32. 2010
    ..Last, we provide additional hypotheses/concepts that are worthy of further study, and how 5-HT neurons may be involved in human disease...
  4. doi request reprint Medullary serotonin neurons and their roles in central respiratory chemoreception
    Matthew R Hodges
    Department of Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Respir Physiol Neurobiol 173:256-63. 2010
    ..Finally, we discuss open questions and future studies that may aid in continuing our advances in understanding central chemoreception...
  5. pmc Changes in neurochemicals within the ventrolateral medullary respiratory column in awake goats after carotid body denervation
    Justin Robert Miller
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin
    J Appl Physiol (1985) 115:1088-98. 2013
    ..We conclude that after CBD, an increase in inhibitory neurotransmitters and a decrease in excitatory neuromodulation within the VMC/preBötC likely contribute to the hypoventilation and attenuated ventilatory CO2 chemoreflex. ..
  6. pmc Interaction between defects in ventilatory and thermoregulatory control in mice lacking 5-HT neurons
    Matthew R Hodges
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520, United States
    Respir Physiol Neurobiol 164:350-7. 2008
    ....
  7. pmc Atropine microdialysis within or near the pre-Botzinger Complex increases breathing frequency more during wakefulness than during NREM sleep
    Clarissa Muere
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    J Appl Physiol (1985) 114:694-704. 2013
    ....
  8. pmc Acute and chronic effects of carotid body denervation on ventilation and chemoreflexes in three rat strains
    Gary C Mouradian
    Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Physiol 590:3335-47. 2012
    ....
  9. pmc Changes in glutamate receptor subunits within the medulla in goats after section of the carotid sinus nerves
    Justin Robert Miller
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin
    J Appl Physiol (1985) 116:1531-42. 2014
    ..The partial recovery of ventilation and the CO2 chemoreflex after CBD parallel a time-dependent return of these receptors to near control levels but likely depend upon additional initiating and maintenance factors for neuroplasticity. ..
  10. pmc Transgenic mice lacking serotonin neurons have severe apnea and high mortality during development
    Matthew R Hodges
    Departments of Neurology and Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT 06510, USA
    J Neurosci 29:10341-9. 2009
    ..These findings provide insight into the mechanisms of sudden infant death syndrome, which has been associated with abnormalities of 5-HT neurons and of cardiorespiratory control...
  11. doi request reprint Defects in breathing and thermoregulation in mice with near-complete absence of central serotonin neurons
    Matthew R Hodges
    Department of Neurology, Yale University, New Haven, Connecticut 06520, USA
    J Neurosci 28:2495-505. 2008
    ..We conclude that the proper function of the 5-HT system is particularly important under conditions of environmental stress and contributes significantly to the hypercapnic ventilatory response and thermoregulatory cold defense...
  12. pmc Contributions of 5-HT neurons to respiratory control: neuromodulatory and trophic effects
    Matthew R Hodges
    Department of Neurology and Cellular and Molecular Physiology, Yale School of Medicine, New Haven, CT 06520, USA
    Respir Physiol Neurobiol 164:222-32. 2008
    ..Future directions of study are also discussed...
  13. pmc Characteristics of microRNAs enriched in specific cell types and primary tissue types in solid organs
    Alison J Kriegel
    Department of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin
    Physiol Genomics 45:1144-56. 2013
    ..These data indicate that the role of miRNAs in determining characteristics of primary tissue types may be different than their role in regulating cell type-specific functions in solid organs. ..
  14. ncbi request reprint Ventilatory phenotypes among four strains of adult rats
    Matthew R Hodges
    Department of Physiology, Medical College of Wisconsin, Wisconsin 53226, USA
    J Appl Physiol (1985) 93:974-83. 2002
    ..Finally, the data establish a foundation for physiological genomic studies aimed at elucidating the genetics of these ventilatory control mechanisms...