Research Topics
| Kelly C HarrisSummaryAffiliation: Medical University of South Carolina Country: USA Publications
Research Grants
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Detail Information
Publications
Human evoked cortical activity to silent gaps in noise: effects of age, attention, and cortical processing speedKelly C Harris
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, Charleston, SC 29425, USA
Ear Hear 33:330-9. 2012..We hypothesized that age-related differences in attention and cognition compound age-related differences at automatic levels of processing, contributing to the robust age effects observed during challenging listening tasks...
Age-related differences in gap detection: effects of task difficulty and cognitive abilityKelly C Harris
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Ave, MSC 550, Charleston, SC 29425 5500, USA
Hear Res 264:21-9. 2010..Taken together, these results suggest that age-related differences in complex measures of auditory temporal processing may be explained, in part, by age-related deficits in processing speed and attention...
Speech recognition in younger and older adults: a dependency on low-level auditory cortexKelly C Harris
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425 5500, USA
J Neurosci 29:6078-87. 2009..More broadly, the results suggest the possibility that aging may exaggerate developmental limitations on the ability to recognize speech...
Age-related differences in sensitivity to small changes in frequency assessed with cortical evoked potentialsKelly C Harris
Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
Hear Res 243:47-56. 2008....
Electrophysiologic correlates of intensity discrimination in cortical evoked potentials of younger and older adultsKelly C Harris
Medical University of South Carolina, Department of Otolarnygology Head and Neck Surgery, 135 Rutledge Avenue, P O Box 250550, Charleston, SC 29425, United States
Hear Res 228:58-68. 2007....
Increased resistance to free radical damage induced by low-level sound conditioningKelly Carney Harris
Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA
Hear Res 213:118-29. 2006..The conditioned animals showed reductions in permanent threshold shift and reduced inner hair cell loss relative to controls. These results reinforce the hypothesis that antioxidants are primary mediators of the conditioning effect...
Prevention of noise-induced hearing loss with Src-PTK inhibitorsKelly Carney Harris
Center for Hearing and Deafness, University at Buffalo, Buffalo, NY 14214, USA
Hear Res 208:14-25. 2005..For all conditions, the results suggest a role for Src-PTK activation in noise-induced hearing loss (NIHL), and that therapeutic intervention with a Src-PTK inhibitor may offer a novel approach in the treatment of NIHL...
Word intelligibility and age predict visual cortex activity during word listeningStefanie E Kuchinsky
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
Cereb Cortex 22:1360-71. 2012..These results suggest that age and stimulus integrity are additive modulators of crossmodal suppression and activation...
Inferior frontal sensitivity to common speech sounds is amplified by increasing word intelligibilityKenneth I Vaden
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, United States
Neuropsychologia 49:3563-72. 2011....
Damage and threshold shift resulting from cochlear exposure to paraquat-generated superoxideEric C Bielefeld
Department of Communicative Disorders and Sciences, Center for Hearing and Deafness, State University of New York at Buffalo, 137 Cary Hall, 3435 Main Street, Buffalo, NY 14214, USA
Hear Res 207:35-42. 2005..Outer and inner hair cell losses were consistent with PTS. The similarities between PQ ototoxicity and noise-induced hearing loss suggest the possibility of similar biochemical pathways involving superoxide...
The role of oxidative stress in noise-induced hearing lossDonald Henderson
Center for Hearing and Deafness, Department of Communicative Disorders and Sciences, State University of New York at Buffalo, Buffalo, New York 14214, USA
Ear Hear 27:1-19. 2006....
Age-related changes in processing speed: unique contributions of cerebellar and prefrontal cortexMark A Eckert
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina Charleston, SC, USA
Front Hum Neurosci 4:10. 2010..These results demonstrate that at least two distinct factors affect age-related changes in processing speed, which might be slowed by mitigating cerebral small vessel disease and factors affecting declines in cerebellar morphology...
In vivo mapping of the human locus coeruleusNoam I Keren
Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
Neuroimage 47:1261-7. 2009..This map can be used to test hypotheses about the LC in human structural and functional imaging studies. Such efforts will contribute to our understanding of attention systems in normal and clinical populations...
Research Grants
- Auditory Temporal Processing in the Aging Ear and BrainKelly Harris; Fiscal Year: 2007....
