Michael Gold

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. doi request reprint The effect of left ventricular electrical delay on AV optimization for cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    Heart Rhythm 10:988-93. 2013
  2. doi request reprint Comparison of fixed tilt and tuned defibrillation waveforms: the PROMISE study
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    J Cardiovasc Electrophysiol 24:323-7. 2013
  3. doi request reprint Effect of QRS duration and morphology on cardiac resynchronization therapy outcomes in mild heart failure: results from the Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) study
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, 25 Courtenay Dr, ART 7031, Charleston, SC 29425 5920, USA
    Circulation 126:822-9. 2012
  4. doi request reprint Head-to-head comparison of arrhythmia discrimination performance of subcutaneous and transvenous ICD arrhythmia detection algorithms: the START study
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 23:359-66. 2012
  5. doi request reprint Acute performance of a right ventricular automatic pacing threshold algorithm for implantable defibrillators
    Michael R Gold
    Medical University of South Carolina, Charleston, SC, USA
    Pacing Clin Electrophysiol 35:259-68. 2012
  6. doi request reprint Prospective comparison of discrimination algorithms to prevent inappropriate ICD therapy: primary results of the Rhythm ID Going Head to Head Trial
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 9:370-7. 2012
  7. pmc Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425 5920, USA
    Circulation 118:2022-8. 2008
  8. ncbi request reprint Effectiveness of rapid atrial pacing for termination of drug refractory atrial fibrillation: results of a dual chamber implantable cardioverter defibrillator trial
    Michael R Gold
    Medical University of South Carolina, Charleston 29425, USA
    Card Electrophysiol Rev 7:341-4. 2003
  9. ncbi request reprint A prospective comparison of AV delay programming methods for hemodynamic optimization during cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 18:490-6. 2007
  10. ncbi request reprint Comparison of stimulation sites within left ventricular veins on the acute hemodynamic effects of cardiac resynchronization therapy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 2:376-81. 2005

Detail Information

Publications67

  1. doi request reprint The effect of left ventricular electrical delay on AV optimization for cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    Heart Rhythm 10:988-93. 2013
    ..Identifying subgroups that benefit from optimization is important to improve CRT outcomes. Pacing at sites of late electrical activation, as assessed by the QLV interval, improves remodeling with CRT...
  2. doi request reprint Comparison of fixed tilt and tuned defibrillation waveforms: the PROMISE study
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    J Cardiovasc Electrophysiol 24:323-7. 2013
    ..Typically a fixed tilt waveform is used for implantable defibrillators (ICDs), but a tuned waveform with duration based on shock impedance may be superior based on theoretical calculations...
  3. doi request reprint Effect of QRS duration and morphology on cardiac resynchronization therapy outcomes in mild heart failure: results from the Resynchronization Reverses Remodeling in Systolic Left Ventricular Dysfunction (REVERSE) study
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, 25 Courtenay Dr, ART 7031, Charleston, SC 29425 5920, USA
    Circulation 126:822-9. 2012
    ..We aimed to assess the impact of baseline QRS duration and morphology and the change in QRS duration with pacing on CRT outcomes in mild heart failure...
  4. doi request reprint Head-to-head comparison of arrhythmia discrimination performance of subcutaneous and transvenous ICD arrhythmia detection algorithms: the START study
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 23:359-66. 2012
    ....
  5. doi request reprint Acute performance of a right ventricular automatic pacing threshold algorithm for implantable defibrillators
    Michael R Gold
    Medical University of South Carolina, Charleston, SC, USA
    Pacing Clin Electrophysiol 35:259-68. 2012
    ..The objective of this study was to evaluate the performance of a new right ventricular (RV) AT algorithm for implantable cardioverter defibrillators (ICDs) using RVcoil to Can evoked response sensing...
  6. doi request reprint Prospective comparison of discrimination algorithms to prevent inappropriate ICD therapy: primary results of the Rhythm ID Going Head to Head Trial
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 9:370-7. 2012
    ..Inappropriate therapy for supraventricular arrhythmias remains a significant source of morbidity in implantable cardioverter-defibrillator (ICD) recipients...
  7. pmc Role of microvolt T-wave alternans in assessment of arrhythmia vulnerability among patients with heart failure and systolic dysfunction: primary results from the T-wave alternans sudden cardiac death in heart failure trial substudy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425 5920, USA
    Circulation 118:2022-8. 2008
    ....
  8. ncbi request reprint Effectiveness of rapid atrial pacing for termination of drug refractory atrial fibrillation: results of a dual chamber implantable cardioverter defibrillator trial
    Michael R Gold
    Medical University of South Carolina, Charleston 29425, USA
    Card Electrophysiol Rev 7:341-4. 2003
    ..It is estimated that early pace-termination of AT/AF episodes may reduce the need for device-based shocks among patients with persistent AF by about half...
  9. ncbi request reprint A prospective comparison of AV delay programming methods for hemodynamic optimization during cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 18:490-6. 2007
    ..The present study was designed to compare the acute effects of AVD programming methods during CRT...
  10. ncbi request reprint Comparison of stimulation sites within left ventricular veins on the acute hemodynamic effects of cardiac resynchronization therapy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 2:376-81. 2005
    ..The purpose of this study was to study the acute hemodynamic effect of left ventricular (LV) stimulation sites within a coronary vein...
  11. doi request reprint Impact of atrial prevention pacing on atrial fibrillation burden: primary results of the Study of Atrial Fibrillation Reduction (SAFARI) trial
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 6:295-301. 2009
    ..SAFARI, a worldwide, prospective, randomized clinical trial, was designed to address these issues and to evaluate the safety and efficacy of a suite of prevention pacing therapies (PPTs) among patients with paroxysmal AF...
  12. ncbi request reprint Rationale and design of a randomized clinical trial to assess the role of overdrive and triggered prevention pacing therapies in reducing atrial fibrillation: the Study of Atrial Fibrillation Reduction (SAFARI)
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Am Heart J 152:231-6. 2006
    ..The inconsistent results and difficulty interpreting the results of past studies stems in part from variability in trial designs, patient populations, and end points...
  13. doi request reprint Acute hemodynamic effects of atrial pacing with cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 20:894-900. 2009
    ..The hemodynamic effects of AP during cardiac resynchronization therapy (CRT) have not been well studied...
  14. doi request reprint The impact of cardiac resynchronization therapy on the incidence of ventricular arrhythmias in mild heart failure
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    Heart Rhythm 8:679-84. 2011
    ..However, the effect of CRT on ventricular arrhythmias is controversial. This is particularly important among patients with mild heart failure (HF), in whom sudden death is a leading cause of mortality...
  15. doi request reprint Temporal stability of defibrillation thresholds with cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, Charleston, South Carolina, USA
    Heart Rhythm 8:1008-13. 2011
    ..Defibrillation thresholds (DFTs) are typically stable over time among patients with implantable cardioverter-defibrillators (ICDs). However, the impact of cardiac resynchronization therapy (CRT) on DFTs has not been studied systematically...
  16. ncbi request reprint Safety of a single successful conversion of ventricular fibrillation before the implantation of cardioverter defibrillators
    Michael R Gold
    MUSC, Division of Cardiology, 96 Jonathan Lucas Street, PO Box 250623, Charleston, SC 29425
    Pacing Clin Electrophysiol 26:483-6. 2003
    ..We hypothesized that a single successful shock at a 14 J may suffice...
  17. ncbi request reprint T wave alternans for ventricular arrhythmia risk stratification
    Michael R Gold
    Department of Medicine, Division of Cardiology, Medical University of South Carolina, 135 Rutledge Avenue, Rutledge Towers Suite 1201, Charleston, SC 29425, USA
    Curr Opin Cardiol 18:1-5. 2003
    ..Despite these encouraging results, the role of TWA to guide clinical therapy still needs to be elucidated better...
  18. ncbi request reprint Comparison of defibrillation efficacy and survival associated with right versus left pectoral placement for implantable defibrillators
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Cardiol 100:243-6. 2007
    ..However, the near doubling of the mortality rate among patients with right-sided implants needs to be considered when recommending such device therapy...
  19. ncbi request reprint Efficacy and temporal stability of reduced safety margins for ventricular defibrillation: primary results from the Low Energy Safety Study (LESS)
    Michael R Gold
    Medical University of South Carolina, Division of Cardiology, Charleston 29425, USA
    Circulation 105:2043-8. 2002
    ..The Low Energy Safety Study (LESS) was a prospective, randomized assessment of the safety margin requirements for modern implantable cardioverter-defibrillator (ICD) systems...
  20. ncbi request reprint Lack of benefit of an active pectoral pulse generator on atrial defibrillation thresholds
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston 29425, USA
    J Cardiovasc Electrophysiol 13:332-5. 2002
    ..However, the effect of an active pectoral can on atrial defibrillation is unknown...
  21. doi request reprint A prospective, randomized comparison of the acute hemodynamic effects of biventricular and left ventricular pacing with cardiac resynchronization therapy
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Heart Rhythm 8:685-91. 2011
    ..This may be due to differences in LV activation pattern, which could be differentially affected by atriventricular (AV) programming or atrial pacing (AP)...
  22. doi request reprint Optimization of superior vena cava coil position and usage for transvenous defibrillation
    Michael Gold
    Medical University of South Carolina, Charleston, SC 29401, USA
    Heart Rhythm 5:394-9. 2008
    ..These studies were done on fixed-tilt waveforms where a large reduction in impedance leads to large phase duration changes...
  23. pmc The relationship between ventricular electrical delay and left ventricular remodelling with cardiac resynchronization therapy
    Michael R Gold
    Medical University of South Carolina, 25 Courtenay Drive, ART 7031, Charleston, SC 29425 5920, USA
    Eur Heart J 32:2516-24. 2011
    ..The aim of the present study was to evaluate the relationship between left ventricular (LV) electrical delay, as measured by the QLV interval, and outcomes in a prospectively designed substudy of the SMART-AV Trial...
  24. ncbi request reprint Advanced rhythm discrimination for implantable cardioverter defibrillators using electrogram vector timing and correlation
    Michael R Gold
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Cardiovasc Electrophysiol 13:1092-7. 2002
    ..The VTC algorithm differentiates normally conducted supraventricular beats from abnormally conducted ventricular beats by comparing the timing and correlation of rate and shock channel electrograms...
  25. ncbi request reprint Clinical predictors of defibrillation thresholds with an active pectoral pulse generator lead system
    Denice M Hodgson
    Department of Medicine, University of Maryland, Baltimore, USA
    Pacing Clin Electrophysiol 25:408-13. 2002
    ..Clinical factors are of limited use for predicting DFTs and identifying those patients who will have high thresholds...
  26. ncbi request reprint Influence of QRS duration on the prognostic value of T wave alternans
    Eric J Rashba
    Department of Medicine, University of Maryland at Baltimore, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 13:770-5. 2002
    ..However, the relationship between TWA and QRS prolongation has not been evaluated. The goal of this study was to determine if QRS prolongation influences the prevalence or prognostic value of TWA...
  27. ncbi request reprint Improved defibrillation efficacy with an ascending ramp waveform in humans
    Stephen R Shorofsky
    University of Maryland, Division of Cardiology, Baltimore, Maryland 21201, USA
    Heart Rhythm 2:388-94. 2005
    ..The purpose of this study was to compare an ascending ramp waveform (RAMP) with a standard, clinically available biphasic truncated exponential waveform (BTE) for defibrillation in humans...
  28. ncbi request reprint A new pacemaker algorithm for the treatment of atrial fibrillation: results of the Atrial Dynamic Overdrive Pacing Trial (ADOPT)
    Mark D Carlson
    Department of Medicine, Case Western Reserve University Medical School and University Hospitals of Cleveland, Cleveland, Ohio 44106, USA
    J Am Coll Cardiol 42:627-33. 2003
    ..Jude Medical Cardiac Rhythm Management Division, Sylmar, California) in patients with sick sinus syndrome and AF...
  29. ncbi request reprint Effect of an active abdominal pulse generator on defibrillation thresholds with a dual-coil, transvenous ICD lead system
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201 1595, USA
    J Cardiovasc Electrophysiol 17:617-20. 2006
    ..The objective of this prospective study was to determine if an active abdominal pulse generator (Can) affects chronic defibrillation thresholds (DFTs) with a dual-coil, transvenous ICD lead system...
  30. ncbi request reprint Enhanced detection of arrhythmia vulnerability using T wave alternans, left ventricular ejection fraction, and programmed ventricular stimulation: a prospective study in subjects with chronic ischemic heart disease
    Eric J Rashba
    Division of Cardiology, Department of Medicine, University of Maryland at Baltimore, Baltimore, Maryland 21201, USA
    J Cardiovasc Electrophysiol 15:170-6. 2004
    ..The aim of this study was to determine if combined assessment of TWA, LVEF, and PVS improves arrhythmia risk stratification...
  31. ncbi request reprint Clinical predictors of atrial defibrillation thresholds with a dual-coil, active pectoral lead system
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, 21201, USA
    Heart Rhythm 2:49-54. 2005
    ..The purpose of this study was to identify clinical predictors of atrial defibrillation thresholds (DFTs) with standard implantable cardioverter-defibrillator (ICD) leads...
  32. ncbi request reprint Effects of selective autonomic blockade on T-wave alternans in humans
    Eric J Rashba
    Division of Cardiology, Department of Medicine, University of Maryland at Baltimore, 21201, USA
    Circulation 105:837-42. 2002
    ..This study tested the hypothesis that the autonomic nervous system influences TWA measurement in high-risk subjects with coronary artery disease...
  33. ncbi request reprint Distal right ventricular coil position reduces defibrillation thresholds
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 14:1036-40. 2003
    ..Distal RV Coil Position Reduces DFTs...
  34. doi request reprint Use of traditional and biventricular implantable cardiac devices for primary and secondary prevention of sudden death
    Matthew H Klein
    Division of Cardiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Cardiol Clin 26:419-31, vi-vii. 2008
    ..More recently, cardiac resynchronization therapy with or without defibrillator capability has been shown to reduce morbidity and mortality among advanced heart failure patients with a prolonged QRS duration...
  35. ncbi request reprint Effect of shock polarity on defibrillation thresholds with a hybrid patch-coil lead system
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
    J Interv Card Electrophysiol 9:391-6. 2003
    ..The objective of this prospective study was to evaluate the effect of shock polarity on defibrillation efficacy at the time of routine pulse generator replacement in patients with a hybrid patch-coil lead system...
  36. ncbi request reprint Comparison of step-down and binary search algorithms for determination of defibrillation threshold in humans
    Stephen R Shorofsky
    Division of Cardiology, Department of Medicine, The University of Maryland, The Department of Veterans Affairs Medical Center, Baltimore, Maryland 21201, USA
    Pacing Clin Electrophysiol 27:218-20. 2004
    ..6 +/- 1.4, whereas by definition, the binary search method always required three shocks. In conclusion, the binary search method is preferable because it is of comparable efficacy and requires fewer shocks...
  37. doi request reprint Role of transesophageal echocardiography among patients with atrial fibrillation undergoing electrophysiology testing
    Rory Priester
    Department of Medicine, Medical University of South Carolina, Charleston, USA
    Am J Cardiol 104:1256-8. 2009
    ..This strategy appears to be a safe method to guide diagnostic testing in this patient population...
  38. ncbi request reprint Limitations of ejection fraction for prediction of sudden death risk in patients with coronary artery disease: lessons from the MUSTT study
    Alfred E Buxton
    Department of Medicine, Cardiology Division, Brown Medical School and Lifespan Academic Medical Center, Providence, Rhode Island 02905, USA
    J Am Coll Cardiol 50:1150-7. 2007
    ..We then constructed an algorithm to predict risk of mortality and sudden death...
  39. ncbi request reprint Role of cardiac resynchronization therapy in asymptomatic and mildly symptomatic heart failure
    Matthew S Forcina
    Medical University of South Carolina, 25 Courtenay Drive, Charleston, SC 29425, USA
    Curr Heart Fail Rep 6:44-8. 2009
    ..Ongoing trials of CRT in such patients will soon provide further data on morbidity and mortality...
  40. ncbi request reprint Selective induction of matrix metalloproteinases and tissue inhibitor of metalloproteinases in atrial and ventricular myocardium in patients with atrial fibrillation
    Rupak Mukherjee
    Division of Cardiothoracic Surgery, Department of Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Cardiol 97:532-7. 2006
    ..Differences in MMP and TIMP profiles may provide diagnostic and mechanistic insights into the pathogenesis of AF with CHF...
  41. doi request reprint The effect of dofetilide on ventricular defibrillation thresholds
    Ron D B Simon
    Division of Cardiology, Medical University of South Carolina, Charleston, South Carolina 29425 5920, USA
    Pacing Clin Electrophysiol 32:24-8. 2009
    ..Dofetilide is a selective class III antiarrhythmic drug that reduces DFTs in a canine model. We hypothesized that dofetilide would reduce DFTs in humans, obviating the need for complex lead systems...
  42. ncbi request reprint Coronary sinus electrode does not reduce atrial defibrillation thresholds
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, 21201, USA
    Heart Rhythm 3:647-52. 2006
    ..Shocking vectors that incorporate an additional electrode in the CS have been used, but it is unclear if they improve atrial DFTs...
  43. pmc SmartDelay determined AV optimization: a comparison of AV delay methods used in cardiac resynchronization therapy (SMART-AV): rationale and design
    Kenneth M Stein
    Department of Medicine, Maurice and Corinne Greenberg Division of Cardiology, Weill Medical College of Cornell University, New York, New York, USA
    Pacing Clin Electrophysiol 33:54-63. 2010
    ..However, some patients do not demonstrate clinical improvement following CRT. It is unclear whether systematic optimization of the programmed atrioventricular (AV) delay improves the rate of clinical response...
  44. doi request reprint Implantable cardioverter-defibrillator therapy for primary prevention of sudden death after alcohol septal ablation of hypertrophic cardiomyopathy
    Frank A Cuoco
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Am Coll Cardiol 52:1718-23. 2008
    ....
  45. ncbi request reprint Sudden cardiac death: the role of risk stratification
    S Luke Kusmirek
    Medical University of South Carolina, Charleston, SC 29425, USA
    Am Heart J 153:25-33. 2007
    ..The article summarizes the current status and applicability of the noninvasive and invasive tests used for sudden cardiac death risk assessment with the emphasis on the increasingly recognized value of microvolt T wave alternans...
  46. ncbi request reprint The influence of gender on arrhythmias
    Robert W Peters
    Division of Cardiology, Department of Medicine, The University of Maryland, Baltimore, MD, USA
    Cardiol Rev 12:97-105. 2004
    ..Lastly, atrial fibrillation is considerably more common in men. There is also some evidence that it is better tolerated by men...
  47. ncbi request reprint Optimization of atrial defibrillation with a dual-coil, active pectoral lead system
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland 21201 1595, USA
    J Cardiovasc Electrophysiol 15:790-4. 2004
    ..The objective of this prospective study was to compare atrial defibrillation thresholds (DFTs) with three shocking configurations that are available with standard ICD leads...
  48. ncbi request reprint Postentrainment activation sequence: diagnostic of the supraventricular tachycardia mechanism?
    D Scott Kirby
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, USA
    J Cardiovasc Electrophysiol 13:410-2. 2002
  49. ncbi request reprint Effect of shock polarity on the efficacy of transthoracic atrial defibrillation
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
    Am Heart J 143:541-5. 2002
    ..The energy requirement for internal ventricular defibrillation is reduced by reversal of shock polarity. The influence of shock polarity on the efficacy of transthoracic atrial defibrillation is unknown...
  50. ncbi request reprint Sustained ventricular tachycardia following alcohol septal ablation for hypertrophic obstructive cardiomyopathy
    Ron D B Simon
    Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Pacing Clin Electrophysiol 28:1354-6. 2005
    ..This case demonstrates probable scar-induced reentrant VT post-alcohol septal ablation, a likely rare but hypothesized complication of this procedure...
  51. ncbi request reprint Efficacy of transthoracic cardioversion of atrial fibrillation using a biphasic, truncated exponential shock waveform at variable initial shock energies
    Eric J Rashba
    Division of Cardiology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    Am J Cardiol 94:1572-4. 2004
    ..Our data suggest that the initial shock energy for CV with this waveform should be 200 J if the patient weighs <90 kg and 360 J if the patient weighs >/=90 kg...
  52. ncbi request reprint Effect of an implantable cardioverter defibrillator with atrial detection and shock therapies on patient-perceived, health-related quality of life
    David M Newman
    Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Am Heart J 145:841-6. 2003
    ..The purpose of this study was to assess the effect of the device on patient-perceived, health-related quality of life (QOL)...
  53. ncbi request reprint Relation of ejection fraction and inducible ventricular tachycardia to mode of death in patients with coronary artery disease: an analysis of patients enrolled in the multicenter unsustained tachycardia trial
    Alfred E Buxton
    Brown Medical School, Providence, RI, USA
    Circulation 106:2466-72. 2002
    ..As such, optimum methods to determine patients most likely to benefit from implantable defibrillator therapy are unclear...
  54. ncbi request reprint Exercise is superior to pacing for T wave alternans measurement in subjects with chronic coronary artery disease and left ventricular dysfunction
    Eric J Rashba
    J Cardiovasc Electrophysiol 13:845-50. 2002
    ..The aim of this prospective study was to compare the prognostic value of TWA measured during bicycle exercise and atrial pacing in a large cohort of high-risk patients with ischemic heart disease and left ventricular dysfunction...
  55. ncbi request reprint Effect of implantable defibrillators on arrhythmic events and mortality in the multicenter unsustained tachycardia trial
    Kerry L Lee
    Department of Biostatistics and Bioinformatics, Duke University Medical Center, Duke Clinical Research Institute and Duke University School of Medicine, Durham, NC 27705, USA
    Circulation 106:233-8. 2002
    ..We performed several statistical analyses to assess the contribution of defibrillators to the observed treatment benefit...
  56. ncbi request reprint T wave alternans: predictor of arrhythmic events?
    Stephen R Shorofsky
    J Cardiovasc Electrophysiol 13:513-4. 2002
  57. ncbi request reprint Cardiovascular responses to repetitive defibrillation during implantable cardioverter-defibrillator testing
    Timothy B Gilbert
    Departments of Anesthesiology, University of Maryland School of Medicine, Baltimore, MD 21201 1595, USA
    J Cardiothorac Vasc Anesth 16:180-5. 2002
    ..To study the effects of electrical applications and subsequent postshock hypotension on myocardial performance and vascular tone during implantable cardioverter-defibrillator (ICD) placement...
  58. ncbi request reprint T wave alternans for ventricular arrhythmia risk stratification
    Ahmed F Osman
    Departments of Medicine and Physiology, University of Maryland, Baltimore, Maryland 21201, USA
    Curr Opin Cardiol 17:1-5. 2002
    ..Despite these encouraging results, the role of TWA to guide clinical therapy still must be better elucidated...
  59. ncbi request reprint Seasonal variation of mortality in the Antiarrhythmics Versus Implantable Defibrillators (AVID) study registry
    Richard L Page
    Department of Internal Medicine, Cardiology Division, University of Washington School of Medicine, Seattle, 98195, USA
    Heart Rhythm 1:435-40. 2004
    ..We postulated that the pattern of death would be nonrandom with respect to temporal variables...
  60. ncbi request reprint Iatrogenic ventricular dyssynchrony: a preventable cause of heart failure with right ventricular pacing?
    Ron D B Simon
    Heart Rhythm 2:252-3. 2005
  61. ncbi request reprint The Rhythm ID Going Head to Head Trial (RIGHT): design of a randomized trial comparing competitive rhythm discrimination algorithms in implantable cardioverter defibrillators
    Ronald D Berger
    Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Cardiovasc Electrophysiol 17:749-53. 2006
    ..RIGHT is a randomized, prospective study that will assess the differential efficacy of ICDs from two different manufacturers. It is the first trial to compare directly competitive ICD rhythm discrimination algorithms on a large scale...
  62. ncbi request reprint ASymptomatic atrial fibrillation and Stroke Evaluation in pacemaker patients and the atrial fibrillation Reduction atrial pacing Trial (ASSERT)
    Stefan H Hohnloser
    Division of Electrophysiology, Department of Cardiology, J W Goethe University, Frankfurt, Germany
    Am Heart J 152:442-7. 2006
    ..This substudy will determine if atrial electrical remodeling is detectable in pacemaker patients and if it is associated with the development of AF...
  63. ncbi request reprint Pacing Evaluation-Atrial SUpport Study in Cardiac Resynchronization Therapy (PEGASUS CRT): design and rationale
    David O Martin
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 153:7-13. 2007
    ..In clinical practice, however, physicians often program CRT devices to have atrial rate support pacing, either by increasing the lower rate limit or by activating the rate sensor...
  64. ncbi request reprint Myocardial contractile reserve as a predictor of cardiac resynchronization therapy response
    J Lacy Sturdivant
    Heart Rhythm 3:414-5. 2006
  65. ncbi request reprint Dynamic changes of T-wave alternans: does it predict short-term arrhythmia vulnerability?
    S Luke Kusmirek
    J Cardiovasc Electrophysiol 18:518-9. 2007
  66. ncbi request reprint Preventing tomorrow's sudden cardiac death today: part I: Current data on risk stratification for sudden cardiac death
    Sana M Al-Khatib
    The Duke Clinical Research Institute, Durham, NC 27715, USA
    Am Heart J 153:941-50. 2007
    ..This article summarizes the presentations and discussions that occurred at that meeting...
  67. ncbi request reprint Preventing tomorrow's sudden cardiac death today: part II: Translating sudden cardiac death risk assessment strategies into practice and policy
    Gillian D Sanders
    Duke Clinical Research Institute, Duke Medical Center, Durham, NC 27715, USA
    Am Heart J 153:951-9. 2007
    ....