Research Topics
| C E EdmistonSummaryAffiliation: Medical College of Wisconsin Country: USA Publications
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Detail Information
Publications
Preoperative shower revisited: can high topical antiseptic levels be achieved on the skin surface before surgical admission?Charles E Edmiston
Division of Vascular Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
J Am Coll Surg 207:233-9. 2008..In this study, chlorhexidine gluconate (CHG) skin concentrations were determined after preoperative showering/skin cleansing using 4% CHG soap or 2% CHG-impregnated polyester cloth...- Reducing the risk of infection in vascular access patients: an in vitro evaluation of an antimicrobial silver nanotechnology luer activated deviceCharles E Edmiston
Surgical Microbiology Research Laboratory, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA
Am J Infect Control 38:421-3. 2010..The present in vitro study compares the antimicrobial property of a silver-nanotechnology LAD to 8 nonantimicrobial LADs... - Reducing the risk of surgical site infections: Does chlorhexidine gluconate provide a risk reduction benefit?Charles E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee, WI Electronic address
Am J Infect Control 41:S49-55. 2013.... 
Microbiology of explanted suture segments from infected and noninfected surgical patientsCharles E Edmiston
Surgical Microbiology Research Laboratory, College of Wisconsin, Milwaukee, Wisconsin, USA
J Clin Microbiol 51:417-21. 2013..Further studies to document the benefit of focused risk reduction strategies to minimize suture contamination and biofilm formation postimplantation are warranted...- Evaluation of an antimicrobial surgical glove to inactivate live human immunodeficiency virus following simulated glove punctureCharles E Edmiston
Division of Vascular Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Surgery 153:225-33. 2013..This study evaluated the efficacy of an innovative integrated antimicrobial glove to reduce transmission of the human immunodeficiency virus (HIV) following a simulated surgical-glove puncture injury... 
Comparative of a new and innovative 2% chlorhexidine gluconate-impregnated cloth with 4% chlorhexidine gluconate as topical antiseptic for preparation of the skin prior to surgeryCharles E Edmiston
Division of Vascular Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Am J Infect Control 35:89-96. 2007..The present study compares the activity of an innovative 2% chlorhexidine gluconate (CHG)-impregnated preoperative skin preparation cloth (PC) with a standard application procedure with a 4% CHG surgical skin preparation (SP)...- Impact of selective antimicrobial agents on staphylococcal adherence to biomedical devicesCharles E Edmiston
Division of Vascular Surgery, Medical College of Wisconsin, 9200 West Wisconsin Ave, Milwaukee, WI 53226, USA
Am J Surg 192:344-54. 2006..The present study investigated the activity of 6 antimicrobial agents against biofilm-forming and non-biofilm-forming strains of staphylococci adherent to the surface of selected biomedical devices... - Comparative in vitro antimicrobial activity of a novel quinolone, garenoxacin, against aerobic and anaerobic microbial isolates recovered from general, vascular, cardiothoracic and otolaryngologic surgical patientsCharles E Edmiston
Division of Vascular Surgery, Medical College of Wisconsin, Milwaukee, WI, USA
J Antimicrob Chemother 56:872-8. 2005..The aim of the study was to analyse the susceptibility of unique and non-duplicate aerobic and anaerobic isolates from surgical patients to a novel des-F(6)-quinolone (garenoxacin) and other selected antimicrobial agents... - Tissue and fluid penetration of garenoxacin in surgical patientsCharles E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Surg Infect (Larchmt) 8:179-88. 2007.... - In vitro activities of moxifloxacin against 900 aerobic and anaerobic surgical isolates from patients with intra-abdominal and diabetic foot infectionsCharles E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Antimicrob Agents Chemother 48:1012-6. 2004..Moxifloxacin exhibited good to excellent antimicrobial activity against most aerobic (90.8%) and anaerobic (97.1%) microorganisms, suggesting that it may be effective for the treatment of polymicrobial surgical infections... - The importance of beta-lactamase resistance in surgical infectionsC E Edmiston
Surgical Microbiology Research Laboratory, Department of Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Surg Infect (Larchmt) 2:S13-22. 2001..Clinical use of these agents has been associated with low rates of resistance and new data suggest they may have a specific role in controlling the emergence and spread of nosocomial infections... - Anaerobic infections in the surgical patient: microbial etiology and therapyCharles E Edmiston
Divisions of Trauma and Critical Care, Medical College of Wisconsin, Milwaukee, WI, 53226, USA
Clin Infect Dis 35:S112-8. 2002..The failure to consider the anaerobic flora as a component in the etiology of mixed surgical infections is associated with a high rate of perioperative and therapeutic failures... - Reducing the risk of surgical site infections: did we really think SCIP was going to lead us to the promised land?Charles E Edmiston
Surgical Microbiology Research Laboratory, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Surg Infect (Larchmt) 12:169-77. 2011..It is estimated that 750,000-1 million SSIs occur in the U.S. each year, utilizing 3.7 million extra hospital days and costing more than $1.6 billion in excess hospital charges... - Molecular epidemiology of microbial contamination in the operating room environment: Is there a risk for infection?Charles E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Surgery 138:573-9; discussion 579-82. 2005..Breaks in surgical technique, host contamination, or hematogenous seeding are suggested as causal factors in these infections. This study implicates contamination of the operating room air as an additional etiology of infection... - Comparative in vitro beta-lactam activity against aerobic and anaerobic surgical isolatesC E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226
Diagn Microbiol Infect Dis 9:105-13. 1988..The results demonstrate that all four compounds exhibited broad antimicrobial activity against facultative and obligate anaerobic surgical isolates from intraabdominal and soft tissue infections... - Vancomycin resistance: when failure becomes an opportunity for leadershipC E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
Ann Pharmacother 30:680-2. 1996..To discuss the emergence of the enterococci as significant nosocomial pathogens and reports of glycopeptide resistance as demonstrating the failure of healthcare professionals to limit the clinical impact of these organisms... - Efficacy of preoperative decontamination of the oral cavityA N Summers
Medical College of Wisconsin, Department of Surgery, Milwaukee, USA
Plast Reconstr Surg 106:895-900; quiz 901. 2000..Although none of the patients in this study developed an infection, recommendations are provided for standardized preoperative treatment of the oral cavity... - Post-antibiotic effect in Bacteroides fragilis groupD J Siverhus
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226
Ann Clin Lab Sci 18:326-36. 1988..fragilis group to anaerobe active beta-lactams produces a prolonged suppression in growth. In theory, a prolonged PAE could influence the dosage regimentation of selective antibiotics... - Prostaglandins and modulation of small bowel myoelectric activityC T Frantzides
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226
Am J Physiol 262:G488-97. 1992..PGE2 has an inhibitory effect both on the spontaneous and PGF2 alpha-induced small intestinal myoelectric and contractile activity... - Penetration of ciprofloxacin and fleroxacin into biliary tractC E Edmiston
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
Antimicrob Agents Chemother 40:787-91. 1996..5 and 8.6 micrograms/ml and 1.2 and 4.4 micrograms/ml, respectively. Both agents demonstrate rapid tissue penetration with persistence at levels appropriate for treatment of biliary pathogens... - Fibrous ball: a new manifestation of chronic defibrillator and pacemaker infectionG H Almassi
Department of Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
Ann Thorac Surg 67:1782-3. 1999..Complete explanation of the defibrillator and pacemaker was done in both patients. New devices were subsequently implanted... - Bacterial adherence to surgical sutures: can antibacterial-coated sutures reduce the risk of microbial contamination?Charles E Edmiston
Division of Vascular Surgery, Department of Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
J Am Coll Surg 203:481-9. 2006.... - Microbiology of middle ear effusions from 292 patients undergoing tympanostomy tube placement for middle ear diseaseDavid M Poetker
Division of Pediatric Otolaryngology, Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Int J Pediatr Otorhinolaryngol 69:799-804. 2005..Future directions include using more specific techniques such as PCR to better understand the microbiology of middle ear effusions... - Activity of antibacterial impregnated central venous catheters against Klebsiella pneumoniaeKaya Yorganci
Hacettepe University, Faculty of Medicine, Department of General Surgery, Ankara, Turkey
Intensive Care Med 28:438-42. 2002..The aim of this study was to evaluate and compare the adherence, persistence and colonization of Klebsiella pneumoniae on catheter surfaces and also to assess bacteriostatic and bactericidal levels... - The monkeypox virus outbreak: reflections from the frontlinesCharles E Edmiston
Department of Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, Wisconsin 53226, USA
Am J Infect Control 31:382-4. 2003 - Fungal biofilm formation on cochlear implant hardware after antibiotic-induced fungal overgrowth within the middle earRicardo Cristobal
Department of Otolaryngology and Communication Sciences, University of Wisconsin, Milwaukee, Milwaukee, WI 53226-3596, USA
Pediatr Infect Dis J 23:774-8. 2004..After 6 weeks, a fungal (Candida) biofilm was demonstrated on the implant surface. In this clinical setting, an antimicrobial strategy using an oral antifungal to prevent fungal overgrowth is a possibility... - Model for antibiotic optimization via neoglycosylation: synthesis of liponeoglycopeptides active against VREByron R Griffith
Division of Pharmaceutical Sciences and the National Drug Discovery Group, University of Wisconsin Madison, Madison, WI 53706, USA
J Am Chem Soc 129:8150-5. 2007.... - Perioperative antibiotic prophylaxis in the gastric bypass patient: do we achieve therapeutic levels?Charles E Edmiston
Department of Surgery, Medical College of Winsconsin, Milwaukee, 53226, USA
Surgery 136:738-47. 2004..Perioperative surgical antibiotic prophylaxis requires that therapeutically effective drug concentrations be present in the tissues... - Operative strategies in aortic graft infections: is complete graft excision always necessary?Joseph P Hart
Division of Vascular Surgery, The Medical College of Wisconsin, Milwaukee, WI 53226, USA
Ann Vasc Surg 19:154-60. 2005..We conclude that in certain high-risk patients who may not tolerate complete graft excision, local resection of infected graft segments may be preferable and leads to similar short- and long-term outcome...