M A Eckert

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc White matter hyperintensities predict low frequency hearing in older adults
    Mark A Eckert
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 14:425-33. 2013
  2. pmc Auditory cortex signs of age-related hearing loss
    Mark A Eckert
    Hearing Research Program, Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 13:703-13. 2012
  3. pmc At the heart of the ventral attention system: the right anterior insula
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
    Hum Brain Mapp 30:2530-41. 2009
  4. doi request reprint Manual and automated measures of superior temporal gyrus asymmetry: concordant structural predictors of verbal ability in children
    Mark A Eckert
    Medical University of South Carolina, Department of Otolaryngology, Head and Neck Surgery, SC 29425, USA
    Neuroimage 41:813-22. 2008
  5. pmc A cross-modal system linking primary auditory and visual cortices: evidence from intrinsic fMRI connectivity analysis
    Mark A Eckert
    Department of Otolaryngology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Hum Brain Mapp 29:848-57. 2008
  6. pmc Age-related effects on word recognition: reliance on cognitive control systems with structural declines in speech-responsive cortex
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 9:252-9. 2008
  7. ncbi request reprint Anomalous sylvian fissure morphology in Williams syndrome
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Neuroimage 33:39-45. 2006
  8. ncbi request reprint The neurobiology of Williams syndrome: cascading influences of visual system impairment?
    M A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250550, Charleston, 29425, USA
    Cell Mol Life Sci 63:1867-75. 2006
  9. ncbi request reprint To modulate or not to modulate: differing results in uniquely shaped Williams syndrome brains
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250550, Charleston, SC 29425, USA
    Neuroimage 32:1001-7. 2006
  10. pmc Speech recognition in younger and older adults: a dependency on low-level auditory cortex
    Kelly C Harris
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425 5500, USA
    J Neurosci 29:6078-87. 2009

Research Grants

  1. Epigenesis of Cerebral Asymmetry in Twins
    Mark Eckert; Fiscal Year: 2004

Detail Information

Publications25

  1. pmc White matter hyperintensities predict low frequency hearing in older adults
    Mark A Eckert
    Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 14:425-33. 2013
    ..These results support the premise that vascular declines are one mechanism underlying age-related changes in low frequency hearing...
  2. pmc Auditory cortex signs of age-related hearing loss
    Mark A Eckert
    Hearing Research Program, Department of Otolaryngology, Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 13:703-13. 2012
    ..These results indicate that Te1.0 is particularly affected by high frequency hearing loss and may be a target for evaluating the efficacy of interventions for hearing loss...
  3. pmc At the heart of the ventral attention system: the right anterior insula
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425 5500, USA
    Hum Brain Mapp 30:2530-41. 2009
    ..These results support the hypothesis that the right aI/fO aids in the coordination and evaluation of task performance across behavioral tasks with varying perceptual and response demands...
  4. doi request reprint Manual and automated measures of superior temporal gyrus asymmetry: concordant structural predictors of verbal ability in children
    Mark A Eckert
    Medical University of South Carolina, Department of Otolaryngology, Head and Neck Surgery, SC 29425, USA
    Neuroimage 41:813-22. 2008
    ..These results demonstrate significant advantages of an automated voxel-based measure over a manual measure of planum temporale asymmetry...
  5. pmc A cross-modal system linking primary auditory and visual cortices: evidence from intrinsic fMRI connectivity analysis
    Mark A Eckert
    Department of Otolaryngology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Hum Brain Mapp 29:848-57. 2008
    ..Our study provides novel, fcMRI-based, support for a neural system involving low-level auditory and visual cortices...
  6. pmc Age-related effects on word recognition: reliance on cognitive control systems with structural declines in speech-responsive cortex
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425 5500, USA
    J Assoc Res Otolaryngol 9:252-9. 2008
    ....
  7. ncbi request reprint Anomalous sylvian fissure morphology in Williams syndrome
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, 29425, USA
    Neuroimage 33:39-45. 2006
    ....
  8. ncbi request reprint The neurobiology of Williams syndrome: cascading influences of visual system impairment?
    M A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250550, Charleston, 29425, USA
    Cell Mol Life Sci 63:1867-75. 2006
    ..While hemizygosity for the transcription factor II-I gene family probably affects the development of visual systems, we also suggest that Lim-kinase 1 hemizygosity exacerbates the impairments in performing space-based actions...
  9. ncbi request reprint To modulate or not to modulate: differing results in uniquely shaped Williams syndrome brains
    Mark A Eckert
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, P O Box 250550, Charleston, SC 29425, USA
    Neuroimage 32:1001-7. 2006
    ....
  10. pmc Speech recognition in younger and older adults: a dependency on low-level auditory cortex
    Kelly C Harris
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425 5500, USA
    J Neurosci 29:6078-87. 2009
    ..More broadly, the results suggest the possibility that aging may exaggerate developmental limitations on the ability to recognize speech...
  11. pmc In vivo mapping of the human locus coeruleus
    Noam I Keren
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, SC 29425, USA
    Neuroimage 47:1261-7. 2009
    ..This map can be used to test hypotheses about the LC in human structural and functional imaging studies. Such efforts will contribute to our understanding of attention systems in normal and clinical populations...
  12. doi request reprint Automated MRI analysis for identification of hippocampal atrophy in temporal lobe epilepsy
    Leonardo Bonilha
    Department of Neurology, Medical University of South Carolina, Charleston, SC, USA
    Epilepsia 50:228-33. 2009
    ..Manual morphometry of the hippocampus is sensitive to detecting HA, but is time-consuming and prone to operator error. Automated MRI morphometry has the potential to provide rapid and accurate assistance in the clinical detection of HA...
  13. pmc Age-related differences in gap detection: effects of task difficulty and cognitive ability
    Kelly C Harris
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Ave, MSC 550, Charleston, SC 29425 5500, USA
    Hear Res 264:21-9. 2010
    ..Taken together, these results suggest that age-related differences in complex measures of auditory temporal processing may be explained, in part, by age-related deficits in processing speed and attention...
  14. pmc Age-related relative volume preservation of the dominant hand cortical region
    Leonardo Bonilha
    Division of Neurology, Medical University of South Carolina, 96 Jonathan Lucas St, 3rd Floor, Charleston, SC 29412, USA
    Brain Res 1305:14-9. 2009
    ..These results are consistent with evidence that disuse leads to atrophy and suggest that age-related declines in gray matter, and perhaps function, may be limited by increasing the use of the non-dominant hand...
  15. pmc Extrahippocampal gray matter loss and hippocampal deafferentation in patients with temporal lobe epilepsy
    Leonardo Bonilha
    Division of Neurology, Department of Neurosciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Epilepsia 51:519-28. 2010
    ..This study aimed to investigate the relationship between hippocampal deafferentation and brain atrophy in MTLE...
  16. doi request reprint How common is brain atrophy in patients with medial temporal lobe epilepsy?
    Leonardo Bonilha
    Division of Neurology, Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Epilepsia 51:1774-9. 2010
    ..This study aimed to evaluate where and how much atrophy is to be expected in an individual patient with MTLE...
  17. pmc Uncoupled leftward asymmetries for planum morphology and functional language processing
    Mark A Eckert
    Medical University of South Carolina, Department of Otolaryngology Head and Neck Surgery, USA
    Brain Lang 98:102-11. 2006
    ..25, p < .05). Individuals with small brains were more likely to demonstrate strong left hemisphere language laterality. These results suggest that language laterality is a multidimensional construct with complex neurological origins...
  18. pmc Selective alterations of white matter associated with visuospatial and sensorimotor dysfunction in turner syndrome
    Marie Holzapfel
    Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5719, USA
    J Neurosci 26:7007-13. 2006
    ..These complementary analyses provide evidence for alterations in white matter pathways that subserve affected and preserved cognitive functions in TS...
  19. ncbi request reprint Modulation of neural connectivity during tongue movement and reading
    Alex G He
    Department of Psychiatry and McKnight Brain Institute, University of Florida, Gainesville, Florida 32610, USA
    Hum Brain Mapp 18:222-32. 2003
    ....
  20. pmc An experiment of nature: brain anatomy parallels cognition and behavior in Williams syndrome
    Allan L Reiss
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305, USA
    J Neurosci 24:5009-15. 2004
    ..These findings point to specific neuroanatomical correlates for the unique topography of cognitive and behavioral features associated with this disorder...
  21. ncbi request reprint Abnormal cortical complexity and thickness profiles mapped in Williams syndrome
    Paul M Thompson
    Laboratory of Neuroimaging, Brain Mapping Division, Department of Neurology, University of California Los Angeles School of Medicine, Los Angeles, California 90095 1769, USA
    J Neurosci 25:4146-58. 2005
    ..03). These findings visualize cortical zones with altered anatomy in WS, which merit additional study with techniques to assess function and connectivity...
  22. ncbi request reprint Reduced parietal and visual cortical activation during global processing in Williams syndrome
    Dean Mobbs
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5719, USA
    Dev Med Child Neurol 49:433-8. 2007
    ..These preliminary results largely confirm previous research findings and neural models implicating neurodevelopmental abnormalities in extended subcortical and cortical visual systems in WS, most notably dorsal-stream pathways...
  23. ncbi request reprint Frontostriatal dysfunction during response inhibition in Williams syndrome
    Dean Mobbs
    Center for Interdisciplinary Brain Sciences Research, Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, California 94305 5719, USA
    Biol Psychiatry 62:256-61. 2007
    ..Here we explore the neural systems that mediate response inhibition in WS...
  24. ncbi request reprint Anatomical correlates of dyslexia: frontal and cerebellar findings
    Mark A Eckert
    Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Brain 126:482-94. 2003
    ..This study may be the first to show that anomalies in a cerebellar-frontal circuit are associated with rapid automatic naming and the double-deficit subtype of dyslexia...
  25. pmc The epigenesis of planum temporale asymmetry in twins
    Mark A Eckert
    Department of Neuroscience, McKnight Brain Institute of the University of Florida, Gainesville, FL 32610, USA
    Cereb Cortex 12:749-55. 2002
    ..Birth weight differences were also related to twin differences in total cerebral volume, but not central sulcus asymmetry. These results suggest that exogenous perinatal factors affect the epigenesis of planar asymmetry development...

Research Grants1

  1. Epigenesis of Cerebral Asymmetry in Twins
    Mark Eckert; Fiscal Year: 2004
    ....