Valerie L Durkalski

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. doi request reprint The effect of covariate adjustment for baseline severity in acute stroke clinical trials with responder analysis outcomes
    Kyra M Garofolo
    Department of Public Health Sciences, Medical University of South Carolina, 135 Cannon Street, Charleston, SC 29425, USA
    Trials 14:98. 2013
  2. ncbi request reprint Analysis of clustered matched-pair data for a non-inferiority study design
    Valerie L Durkalski
    TCIG STATS, The Clinical Innovation Group, MUSC Foundation for Research Development, Charleston, SC, USA
    Stat Med 22:279-90. 2003
  3. ncbi request reprint Analysis of clustered matched-pair data
    Valerie L Durkalski
    The Clinical Innovation Group TCIG, Medical University of South Carolina, Foundation for Research Development, Charleston, SC 29401, USA
    Stat Med 22:2417-28. 2003
  4. doi request reprint Challenges in the design and analysis of non-inferiority trials: a case study
    Valerie Durkalski
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425 8150, USA
    Clin Trials 8:601-8. 2011
  5. doi request reprint A web-based clinical trial management system for a sham-controlled multicenter clinical trial in depression
    Valerie Durkalski
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC, USA
    Clin Trials 7:174-82. 2010
  6. doi request reprint Re-formulating non-inferiority trials as superiority trials: The case of binary outcomes
    Valerie L Durkalski
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, 29425 8150, USA
    Biom J 51:185-92. 2009
  7. pmc Measuring episodic abdominal pain and disability in suspected sphincter of Oddi dysfunction
    Valerie Durkalski
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, 135 Cannon Street, Ste 303, Charleston, SC 29425, United States
    World J Gastroenterol 16:4416-21. 2010
  8. ncbi request reprint Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia
    Peter B Cotton
    Department of Gastroenterology, The Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
    JAMA 291:1713-9. 2004
  9. ncbi request reprint Open-label trial of escitalopram in the treatment of posttraumatic stress disorder
    Sophie Robert
    Mental Health Service, Ralph H Johnson VA Medical Center, Charleston, SC 29401, USA
    J Clin Psychiatry 67:1522-6. 2006
  10. ncbi request reprint Therapeutic inertia is an impediment to achieving the Healthy People 2010 blood pressure control goals
    Eni C Okonofua
    Medical University of South Carolina, Charleston, SC 29425, USA
    Hypertension 47:345-51. 2006

Detail Information

Publications14

  1. doi request reprint The effect of covariate adjustment for baseline severity in acute stroke clinical trials with responder analysis outcomes
    Kyra M Garofolo
    Department of Public Health Sciences, Medical University of South Carolina, 135 Cannon Street, Charleston, SC 29425, USA
    Trials 14:98. 2013
    ..This research aims to investigate the effect of covariate adjustment in the responder analysis framework in order to determine the appropriate analytic method...
  2. ncbi request reprint Analysis of clustered matched-pair data for a non-inferiority study design
    Valerie L Durkalski
    TCIG STATS, The Clinical Innovation Group, MUSC Foundation for Research Development, Charleston, SC, USA
    Stat Med 22:279-90. 2003
    ..This paper proposes a Wald-type test statistic for a non-inferiority hypothesis and applies it to the comparison of two diagnostic procedures...
  3. ncbi request reprint Analysis of clustered matched-pair data
    Valerie L Durkalski
    The Clinical Innovation Group TCIG, Medical University of South Carolina, Foundation for Research Development, Charleston, SC 29401, USA
    Stat Med 22:2417-28. 2003
    ..Using Monte Carlo simulation, the size and power of the proposed test are compared to those of two currently available methods. To illustrate practical application, clustered matched-pair data from two clinical studies are analysed...
  4. doi request reprint Challenges in the design and analysis of non-inferiority trials: a case study
    Valerie Durkalski
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425 8150, USA
    Clin Trials 8:601-8. 2011
    ..To date, there has been relatively little in the literature documenting actual experiences with implementing available methodology for non-inferiority trials...
  5. doi request reprint A web-based clinical trial management system for a sham-controlled multicenter clinical trial in depression
    Valerie Durkalski
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, SC, USA
    Clin Trials 7:174-82. 2010
    ..Web-based data management systems are beginning to meet this need but what distinguishes one system from the other are user needs/requirements and cost...
  6. doi request reprint Re-formulating non-inferiority trials as superiority trials: The case of binary outcomes
    Valerie L Durkalski
    Department of Biostatistics, Bioinformatics and Epidemiology, Medical University of South Carolina, Charleston, 29425 8150, USA
    Biom J 51:185-92. 2009
    ....
  7. pmc Measuring episodic abdominal pain and disability in suspected sphincter of Oddi dysfunction
    Valerie Durkalski
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, 135 Cannon Street, Ste 303, Charleston, SC 29425, United States
    World J Gastroenterol 16:4416-21. 2010
    ..To evaluate the reliability of an instrument that measures disability arising from episodic abdominal pain in patients with suspected sphincter of Oddi dysfunction (SOD)...
  8. ncbi request reprint Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia
    Peter B Cotton
    Department of Gastroenterology, The Digestive Disease Center, Medical University of South Carolina, Charleston 29425, USA
    JAMA 291:1713-9. 2004
    ..Computed tomographic colonography (CTC), also known as virtual colonoscopy, has been reported to be reasonably accurate in the diagnosis of colorectal neoplasia in studies performed at expert centers...
  9. ncbi request reprint Open-label trial of escitalopram in the treatment of posttraumatic stress disorder
    Sophie Robert
    Mental Health Service, Ralph H Johnson VA Medical Center, Charleston, SC 29401, USA
    J Clin Psychiatry 67:1522-6. 2006
    ..Its S-enantiomer escitalopram, which may have faster onset and greater magnitude of effect than citalopram in other conditions, has not yet been investigated in PTSD...
  10. ncbi request reprint Therapeutic inertia is an impediment to achieving the Healthy People 2010 blood pressure control goals
    Eni C Okonofua
    Medical University of South Carolina, Charleston, SC 29425, USA
    Hypertension 47:345-51. 2006
    ..TI has a major impact on BP control in hypertensive subjects receiving regular care. Reducing TI is critical in attaining the Healthy People 2010 goal of controlling hypertension in 50% of all patients...
  11. pmc Rationale and design: telephone-delivered behavioral skills interventions for Blacks with Type 2 diabetes
    Leonard E Egede
    Center for Disease Prevention and Health Interventions for Diverse Populations, Ralph H, Johnson VAMC, Charleston, SC, USA
    Trials 11:35. 2010
    ..This study provides a unique opportunity to address this gap in the literature...
  12. doi request reprint Nosocomial infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus: relationships with antibiotic use and cost drivers
    Patrick D Mauldin
    Department of Clinical Pharmacy and Outcome Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA
    Ann Pharmacother 42:317-26. 2008
    ....
  13. ncbi request reprint The virtual colonoscopy study: a large multicenter clinical trial designed to compare two diagnostic screening procedures
    Valerie L Durkalski
    TCIG STATS, The Clinical Innovation Group, MUSC Foundation for Research and Development, The Medical University of South Carolina, Charleston, SC, USA
    Control Clin Trials 23:570-83. 2002
    ..Strategies for the design and implementation of the study are shared as well as the challenges encountered...
  14. ncbi request reprint Analysis of trichotomous pharmaceutical endpoints
    Vance W Berger
    Biometry Research Group, National Cancer Institute, University of Maryland, Baltimore County, Maryland, USA
    J Biopharm Stat 15:739-45. 2005
    ..The purpose of this paper is to fill this gap by offering an objective approach for parameter selection, and to provide real data examples to illustrate the use of this objective approach...