Stacia M DeSantis

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc Gender differences in the effect of early life trauma on hypothalamic-pituitary-adrenal axis functioning
    Stacia M DeSantis
    Department of Medicine, Division of Biostatistics and Epidemiology, Medical University of South Carolina, 135 Cannon Street, Charleston, SC 29425, USA
    Depress Anxiety 28:383-92. 2011
  2. pmc Supervised Bayesian latent class models for high-dimensional data
    Stacia M DeSantis
    Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    Stat Med 31:1342-60. 2012
  3. pmc Hidden Markov models for zero-inflated Poisson counts with an application to substance use
    Stacia M DeSantis
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Stat Med 30:1678-94. 2011
  4. pmc Non-treatment laboratory stress- and cue-reactivity studies are associated with decreased substance use among drug-dependent individuals
    Stacia M DeSantis
    Department of Biostatistics, Bioinformatics, and Epidemiology, 135 Cannon Street Suite 303, Charleston, SC 29425, USA
    Drug Alcohol Depend 105:227-33. 2009
  5. pmc Reactivity to laboratory stress provocation predicts relapse to cocaine
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Drug Alcohol Depend 106:21-7. 2010
  6. doi request reprint Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory
    Bryan K Tolliver
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 36:106-13. 2010
  7. pmc Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues
    Angela E Waldrop
    Medical University of South Carolina, 67 President St, Charleston, SC 29403, United States
    Psychoneuroendocrinology 35:798-806. 2010
  8. doi request reprint Impaired cognitive performance in subjects with methamphetamine dependence during exposure to neutral versus methamphetamine-related cues
    Bryan K Tolliver
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
    Am J Drug Alcohol Abuse 38:251-9. 2012
  9. pmc Gender differences in craving and cue reactivity to smoking and negative affect/stress cues
    Michael E Saladin
    Department of Health Sciences and Research, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Addict 21:210-20. 2012
  10. pmc Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate
    James J Prisciandaro
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 36:490-6. 2012

Detail Information

Publications33

  1. pmc Gender differences in the effect of early life trauma on hypothalamic-pituitary-adrenal axis functioning
    Stacia M DeSantis
    Department of Medicine, Division of Biostatistics and Epidemiology, Medical University of South Carolina, 135 Cannon Street, Charleston, SC 29425, USA
    Depress Anxiety 28:383-92. 2011
    ..Individuals with major depressive disorder, posttraumatic stress disorder, bipolar disorder, or psychotic or eating disorders were excluded...
  2. pmc Supervised Bayesian latent class models for high-dimensional data
    Stacia M DeSantis
    Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA
    Stat Med 31:1342-60. 2012
    ..Fitting models with and without YKL-40 highlights a subgroup of patients who have glioblastoma (GBM) diagnosis but appear to have better prognosis than the typical GBM patient...
  3. pmc Hidden Markov models for zero-inflated Poisson counts with an application to substance use
    Stacia M DeSantis
    Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC 29425, USA
    Stat Med 30:1678-94. 2011
    ..We adopt a Bayesian approach to model fitting, and use the conditional predictive ordinate statistic to demonstrate that the zero-inflated Poisson hidden Markov model outperforms other models for longitudinal count data...
  4. pmc Non-treatment laboratory stress- and cue-reactivity studies are associated with decreased substance use among drug-dependent individuals
    Stacia M DeSantis
    Department of Biostatistics, Bioinformatics, and Epidemiology, 135 Cannon Street Suite 303, Charleston, SC 29425, USA
    Drug Alcohol Depend 105:227-33. 2009
    ..This study examines whether participation in such studies alters drug-seeking behavior and which patient attributes contribute to increased use...
  5. pmc Reactivity to laboratory stress provocation predicts relapse to cocaine
    Sudie E Back
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, MSC861, Charleston, SC 29425, United States
    Drug Alcohol Depend 106:21-7. 2010
    ..Elevated levels of stress have been associated with relapse to cocaine; however, the nature of this association is not well understood...
  6. doi request reprint Determinants of cue-elicited craving and physiologic reactivity in methamphetamine-dependent subjects in the laboratory
    Bryan K Tolliver
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Drug Alcohol Abuse 36:106-13. 2010
    ..In this study, clinical and demographic correlates of methamphetamine craving and the optimal conditions for its measurement in the laboratory are explored...
  7. pmc Community-dwelling cocaine-dependent men and women respond differently to social stressors versus cocaine cues
    Angela E Waldrop
    Medical University of South Carolina, 67 President St, Charleston, SC 29403, United States
    Psychoneuroendocrinology 35:798-806. 2010
    ..11]). No gender differences were found in ACTH responses to the CUE. The results are reviewed in the context of the existing literature on gender differences in cocaine dependence and potential implications for treatment are discussed...
  8. doi request reprint Impaired cognitive performance in subjects with methamphetamine dependence during exposure to neutral versus methamphetamine-related cues
    Bryan K Tolliver
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
    Am J Drug Alcohol Abuse 38:251-9. 2012
    ..Exposure to methamphetamine-related cues can elicit intense craving in chronic users of the drug, but the effects of exposure to drug cues on cognitive performance in these individuals are unknown...
  9. pmc Gender differences in craving and cue reactivity to smoking and negative affect/stress cues
    Michael E Saladin
    Department of Health Sciences and Research, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Addict 21:210-20. 2012
    ..While there were no gender differences in responses to smoking cues, women trended towards higher arousal ratings. Implications of the findings for treatment and tobacco-related morbidity and mortality are discussed...
  10. pmc Impact of depressive symptoms on future alcohol use in patients with co-occurring bipolar disorder and alcohol dependence: a prospective analysis in an 8-week randomized controlled trial of acamprosate
    James J Prisciandaro
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Alcohol Clin Exp Res 36:490-6. 2012
    ..The present study examined the impact of depressive symptoms and alcohol craving on proximal alcohol use in patients with co-occurring bipolar disorder and alcohol dependence...
  11. pmc Influence of cocaine dependence and early life stress on pituitary-adrenal axis responses to CRH and the Trier social stressor
    Megan M Moran-Santa Maria
    Department of Psychiatry and Behavioral Sciences, Clinical Neuroscience Division, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, United States
    Psychoneuroendocrinology 35:1492-500. 2010
    ....
  12. pmc A latent class model with hidden Markov dependence for array CGH data
    Stacia M DeSantis
    Department of Biostatistics, Bioinformatics, and Epidemiology, Medical University of South Carolina, 135 Cannon Street, Suite 303, Charleston, South Carolina 29403, USA
    Biometrics 65:1296-305. 2009
    ..We demonstrate our technique on a study of brain tumors, for which our approach is capable of identifying subsets of tumors with different genomic profiles, and differentiates classes by survival much better than unsupervised methods...
  13. pmc Extinction of drug cue reactivity in methamphetamine-dependent individuals
    Kimber L Price
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, 29425, USA
    Behav Res Ther 48:860-5. 2010
    ..These results indicate that extinction of drug cue conditioned responding occurs in methamphetamine-dependent individuals, offering promise for the development of extinction- based treatment strategies...
  14. pmc The impact of clinical and demographic variables on cognitive performance in methamphetamine-dependent individuals in rural South Carolina
    Kimber L Price
    Division of Clinical Neuroscience, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29403, USA
    Am J Addict 20:447-55. 2011
    ..Characterization of the impact of clinical and/or demographic features on cognitive deficits could be important in guiding the development of treatment interventions...
  15. pmc Simultaneous modeling of the impact of treatments on alcohol consumption and quality of life in the COMBINE study: a coupled hidden Markov analysis
    James J Prisciandaro
    Clinical Neuroscience Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC 29425, USA
    Alcohol Clin Exp Res 36:2141-9. 2012
    ..The goal of this study was to evaluate longitudinal associations between treatment status, alcohol consumption, and QOL in the Combined Pharmacotherapies and Behavioral Interventions for Alcohol Dependence (COMBINE) study...
  16. pmc A randomized, placebo-controlled laboratory study of the effects of D-cycloserine on craving in cocaine-dependent individuals
    Kimber L Price
    Department of Psychiatry and Behavioral Sciences, Division of Clinical Neuroscience, Medical University of South Carolina, 67 President Street MSC 861, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 226:739-46. 2013
    ..D-Cycloserine (DCS), a partial glutamate N-methyl-D-aspartate (NMDA) receptor agonist, enhances extinction of conditioned fear responding; preliminary data suggest that it may facilitate extinction of drug cue reactivity...
  17. pmc Differential effects of aprotinin and tranexamic acid on outcomes and cytokine profiles in neonates undergoing cardiac surgery
    Eric M Graham
    Division of Cardiology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
    J Thorac Cardiovasc Surg 143:1069-76. 2012
    ....
  18. pmc Response to corticotropin-releasing hormone infusion in cocaine-dependent individuals
    Kathleen T Brady
    Department of Psychiatry and Behavioral Sciences, Clinical Neurosciences Division, Medical University of South Carolina, 67 President St, PO Box 250861, Charleston, SC 29425, USA
    Arch Gen Psychiatry 66:422-30. 2009
    ..Little is known about the response of cocaine-dependent individuals to CRH administration...
  19. pmc Association of elevated cytokines with childhood adversity in a sample of healthy adults
    Karen J Hartwell
    Department of Psychiatry and Behavioral Neurosciences, Clinical Neuroscience Division, Medical University of South Carolina, 125 Doughty Street, Charleston, SC 29425, USA
    J Psychiatr Res 47:604-10. 2013
    ..In this study, the relationships between childhood adversity and cytokine and C-reactive protein (CRP) levels in healthy adults were examined...
  20. pmc Some considerations for excess zeroes in substance abuse research
    Dipankar Bandyopadhyay
    Division of Biostatistics and Epidemiology, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Am J Drug Alcohol Abuse 37:376-82. 2011
    ..However, there is a need to consider the design aspects of those studies before using such a statistical model to ascertain the sources of zeroes...
  21. pmc D-cycloserine and cocaine cue reactivity: preliminary findings
    Kimber L Price
    Medical University of South Carolina, Department of Psychiatry, Clinical Neuroscience Division, 67 President Street, Charleston, SC 29425, USA
    Am J Drug Alcohol Abuse 35:434-8. 2009
    ..D-cycloserine (DCS), a partial glutamate N-methyl-D-aspartic acid (NMDA) receptor agonist, enhances extinction of conditioned fear responding in rodents and facilitates exposure-based learning in humans with anxiety disorders...
  22. doi request reprint Plasma profiles of matrix metalloproteinases and tissue inhibitors of the metalloproteinases predict recurrence of atrial fibrillation following cardioversion
    Rupak Mukherjee
    Division of Cardiothoracic Surgery, Medical University of South Carolina, 770 MUSC Complex, Suite 326, Charleston, SC 29425, USA
    J Cardiovasc Transl Res 6:528-35. 2013
    ..Circulating levels of MMPs and TIMPs predict AF recurrence postcardioversion and may be used in a novel biomarker panel to guide AF stratification and therapy...
  23. pmc Menstrual cycle and cue reactivity in women smokers
    Kevin M Gray
    Youth Division, Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, P O Box 250861, Charleston, SC 29425, USA
    Nicotine Tob Res 12:174-8. 2010
    ..The present study sought to explore the influence of menstrual cycle phase on reactivity to smoking in vivo and stressful imagery cues in a sample of non-treatment-seeking women smokers...
  24. doi request reprint High-osmolarity saline in neurocritical care: systematic review and meta-analysis
    Christos Lazaridis
    Department of Neurosciences, Neurosciences Intensive Care Unit, Medical University of South Carolina, Charleston, SC, USA
    Crit Care Med 41:1353-60. 2013
    ..We conducted a systematic literature review on the use of 23.4% saline in neurocritically ill patients and a meta-analysis of the effect of 23.4% saline on intracranial pressure reduction...
  25. pmc Early postoperative outcomes and blood product utilization in adult cardiac surgery: the post-aprotinin era
    Stacia M DeSantis
    Department of Biostatistics and Epidemiology, Medical University of South Carolina and Ralph H Johnson Department of Veterans Affairs Medical Center, Charleston, SC, USA
    Circulation 124:S62-9. 2011
    ..This study tested the hypothesis that early postoperative adverse events and blood product utilization would affected in this post-aprotinin era...
  26. ncbi request reprint Plasma biomarkers that reflect determinants of matrix composition identify the presence of left ventricular hypertrophy and diastolic heart failure
    Michael R Zile
    Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA
    Circ Heart Fail 4:246-56. 2011
    ....
  27. ncbi request reprint A penalized latent class model for ordinal data
    Stacia M DeSantis
    Department of Biostatistics, Harvard University, 655 Huntington Avenue, Boston, MA 02115, USA
    Biostatistics 9:249-62. 2008
    ..We illustrate our methodology in a study of schwannoma, a peripheral nerve sheath tumor, that included 3 clinical subtypes and 23 ordinal histological measures...
  28. pmc Relationship between the temporal profile of plasma microRNA and left ventricular remodeling in patients after myocardial infarction
    Michael R Zile
    Division of Cardiology, Department of Medicine, Medical University of South Carolina and Ralph H Johnson Department of Veterans Affairs Medical Center, Charleston, SC, USA
    Circ Cardiovasc Genet 4:614-9. 2011
    ..The current pilot study tested the hypotheses that plasma miRs could be reliably measured in post-MI patients and that there is a relationship between temporal changes in specific miRs and post-MI LV structural remodeling...
  29. doi request reprint A randomized, double-blind, placebo-controlled clinical trial of acamprosate in alcohol-dependent individuals with bipolar disorder: a preliminary report
    Bryan K Tolliver
    Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, 67 President Street, Charleston, SC 29425, USA
    Bipolar Disord 14:54-63. 2012
    ..The current study assessed the effects of acamprosate on alcohol use and mood symptoms in subjects with co-occurring bipolar disorder and active alcohol dependence...
  30. ncbi request reprint Telestroke in South Carolina
    Christos Lazaridis
    Division of Vascular Neurology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina Division of Neurocritical Care, Department of Neurosciences, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina Electronic address
    J Stroke Cerebrovasc Dis 22:946-50. 2013
    ....
  31. pmc Perfusion network shift during seizures in medial temporal lobe epilepsy
    Karen M Sequeira
    Comprehensive Epilepsy Center, Division of Neurology, Department of Neurosciences, Medical University of South Carolina, Charleston, SC, USA
    PLoS ONE 8:e53204. 2013
    ..In this study, we aimed to investigate state specific (i.e. ictal versus interictal) perfusional limbic networks in patients with MTLE...
  32. doi request reprint Liberation of neurosurgical patients from mechanical ventilation and tracheostomy in neurocritical care
    Christos Lazaridis
    Department of Neurosciences Neurosciences Critical Care, Medical University of South Carolina, Charleston, SC 29425, USA
    J Crit Care 27:417.e1-8. 2012
    ..Future studies are required to better assess indicators for extubation readiness, evaluate the predictors of extubation failure in brain-injured patients, and define the most appropriate timing for a tracheostomy...
  33. pmc Standardized preoperative corticosteroid treatment in neonates undergoing cardiac surgery: results from a randomized trial
    Eric M Graham
    Division of Cardiology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
    J Thorac Cardiovasc Surg 142:1523-9. 2011
    ..We sought to determine whether preoperative methylprednisolone would improve postoperative recovery in neonates requiring cardiac surgery...