Chin Wei Chiao

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. pmc P2X7 receptor activation amplifies lipopolysaccharide-induced vascular hyporeactivity via interleukin-1 beta release
    Chin Wei Chiao
    Department of Physiology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
    J Pharmacol Exp Ther 326:864-70. 2008
  2. pmc Interleukin-10 inhibits the in vivo and in vitro adverse effects of TNF-alpha on the endothelium of murine aorta
    Saiprasad M Zemse
    Department of Physiology, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Heart Circ Physiol 299:H1160-7. 2010
  3. doi request reprint P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction
    Chin Wei Chiao
    Department of Physiology, Georgia Regents University, Augusta, GA 30912 300, USA
    Clin Sci (Lond) 125:131-41. 2013
  4. pmc Increased activation of stromal interaction molecule-1/Orai-1 in aorta from hypertensive rats: a novel insight into vascular dysfunction
    Fernanda R C Giachini
    Medical College of Georgia, Department of Physiology, 1120 15th St, CA 3141, Augusta, GA 30912 3000, USA
    Hypertension 53:409-16. 2009
  5. pmc The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries
    J Eduardo da Silva-Santos
    Department of Physiology, Medical College of Georgia, Augusta, GA, USA
    Crit Care Med 37:1716-23. 2009
  6. pmc Vascular Smooth Muscle Cell Signaling Mechanisms for Contraction to Angiotensin II and Endothelin-1
    Brandi M Wynne
    Medical College of Georgia, Augusta, GA 30912
    J Am Soc Hypertens 3:84-95. 2009
  7. ncbi request reprint N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia
    Chin Wei Chiao
    Institute of Pharmacology, College of Medicine, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei 100, Taiwan
    Eur J Pharmacol 535:291-300. 2006
  8. ncbi request reprint Thaliporphine increases survival rate and attenuates multiple organ injury in LPS-induced endotoxaemia
    Chin Wei Chiao
    Institute of Pharmacology, College of Medicine, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei, 100, Taiwan
    Naunyn Schmiedebergs Arch Pharmacol 371:34-43. 2005

Detail Information

Publications8

  1. pmc P2X7 receptor activation amplifies lipopolysaccharide-induced vascular hyporeactivity via interleukin-1 beta release
    Chin Wei Chiao
    Department of Physiology, Medical College of Georgia, 1120 15th Street, Augusta, GA 30912, USA
    J Pharmacol Exp Ther 326:864-70. 2008
    ..Thus, activation of P2X(7) receptor amplifies LPS-induced hyporeactivity in mouse endothelium-intact aorta, which is associated with IL-1beta-mediated release of nitric oxide by iNOS...
  2. pmc Interleukin-10 inhibits the in vivo and in vitro adverse effects of TNF-alpha on the endothelium of murine aorta
    Saiprasad M Zemse
    Department of Physiology, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Heart Circ Physiol 299:H1160-7. 2010
    ..In conclusion, the anti-inflammatory cytokine IL-10 prevents impairment in endothelium-dependent vasorelaxation caused by TNF-α by protecting eNOS expression...
  3. doi request reprint P2X7 receptor activation contributes to an initial upstream mechanism of lipopolysaccharide-induced vascular dysfunction
    Chin Wei Chiao
    Department of Physiology, Georgia Regents University, Augusta, GA 30912 300, USA
    Clin Sci (Lond) 125:131-41. 2013
    ..These results suggest that P2X7 receptor activation involves an initial upstream mechanism of LPS-induced vascular dysfunction, which is associated with IL-1β-mediated eNOS, COX2 activation and TNFα release...
  4. pmc Increased activation of stromal interaction molecule-1/Orai-1 in aorta from hypertensive rats: a novel insight into vascular dysfunction
    Fernanda R C Giachini
    Medical College of Georgia, Department of Physiology, 1120 15th St, CA 3141, Augusta, GA 30912 3000, USA
    Hypertension 53:409-16. 2009
    ..Augmented activation of STIM-1/Orai-1 may represent the mechanism that leads to impaired control of intracellular Ca(2+) levels in hypertension...
  5. pmc The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries
    J Eduardo da Silva-Santos
    Department of Physiology, Medical College of Georgia, Augusta, GA, USA
    Crit Care Med 37:1716-23. 2009
    ..We investigated whether a reduced activity in the Rho-A/Rho-kinase pathway could be involved in the impaired vascular reactivity observed in septic shock...
  6. pmc Vascular Smooth Muscle Cell Signaling Mechanisms for Contraction to Angiotensin II and Endothelin-1
    Brandi M Wynne
    Medical College of Georgia, Augusta, GA 30912
    J Am Soc Hypertens 3:84-95. 2009
    ..In pathological conditions such as hypertension, alterations in these cellular signaling components can lead to an over stimulated state causing maintained vasoconstriction and blood pressure elevation...
  7. ncbi request reprint N-Allylsecoboldine as a novel agent prevents acute renal failure during endotoxemia
    Chin Wei Chiao
    Institute of Pharmacology, College of Medicine, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei 100, Taiwan
    Eur J Pharmacol 535:291-300. 2006
    ..However, the role of alpha1-adrenoceptor antagonism for N-allylsecoboldine in sepsis remains unclear...
  8. ncbi request reprint Thaliporphine increases survival rate and attenuates multiple organ injury in LPS-induced endotoxaemia
    Chin Wei Chiao
    Institute of Pharmacology, College of Medicine, National Taiwan University, No 1, Sec 1, Jen Ai Road, Taipei, 100, Taiwan
    Naunyn Schmiedebergs Arch Pharmacol 371:34-43. 2005
    ..These beneficial effects of thaliporphine may be attributed to the suppression of TNF-alpha, NO. and O(2).(-) production...