Catherine S Chew

Summary

Affiliation: Medical College of Georgia
Country: USA

Publications

  1. ncbi Lasp-1 binds to non-muscle F-actin in vitro and is localized within multiple sites of dynamic actin assembly in vivo
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    J Cell Sci 115:4787-99. 2002
  2. pmc Cytochrome c oxidase subunit IV as a marker of protein kinase Cepsilon function in neonatal cardiac myocytes: implications for cytochrome c oxidase activity
    Mourad Ogbi
    Department of Pharmacology and Toxicology, School of Medicine, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 2300, USA
    Biochem J 382:923-32. 2004
  3. ncbi IQGAPs are differentially expressed and regulated in polarized gastric epithelial cells
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    Am J Physiol Gastrointest Liver Physiol 288:G376-87. 2005
  4. pmc Lasp1 gene disruption is linked to enhanced cell migration and tumor formation
    Han Zhang
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia, USA
    Physiol Genomics 38:372-85. 2009
  5. pmc Calcium/calmodulin-dependent phosphorylation of tumor protein D52 on serine residue 136 may be mediated by CAMK2delta6
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Gastrointest Liver Physiol 295:G1159-72. 2008
  6. ncbi Drebrin E2 is differentially expressed and phosphorylated in parietal cells in the gastric mucosa
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Sanders R and E Bldg, Rm CB 2803, Augusta, GA, USA
    Am J Physiol Gastrointest Liver Physiol 289:G320-31. 2005
  7. pmc Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    Am J Physiol Gastrointest Liver Physiol 295:G37-G44. 2008
  8. ncbi Gene expression profiling of gastrin target genes in parietal cells
    Renu N Jain
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109 0622, USA
    Physiol Genomics 24:124-32. 2006
  9. pmc Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice
    Renu N Jain
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109 2200, USA
    J Clin Invest 118:2459-70. 2008
  10. ncbi Parietal cell hyperstimulation and autoimmune gastritis in cholera toxin transgenic mice
    Lymari Lopez-Diaz
    Department of Molecular and Integrative Physiology, University of Michigan, 7761 Medical Science II Building, Ann Arbor, MI 48109, USA
    Am J Physiol Gastrointest Liver Physiol 290:G970-9. 2006

Collaborators

Detail Information

Publications11

  1. ncbi Lasp-1 binds to non-muscle F-actin in vitro and is localized within multiple sites of dynamic actin assembly in vivo
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    J Cell Sci 115:4787-99. 2002
    ....
  2. pmc Cytochrome c oxidase subunit IV as a marker of protein kinase Cepsilon function in neonatal cardiac myocytes: implications for cytochrome c oxidase activity
    Mourad Ogbi
    Department of Pharmacology and Toxicology, School of Medicine, Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 2300, USA
    Biochem J 382:923-32. 2004
    ..The in vitro phosphorylation of COIV reflects a novel approach for monitoring PKCepsilon function in NCMs. Furthermore, PKCepsilon probably interacts with COIV in NCM mitochondria to enhance electron-transport chain complex IV activity...
  3. ncbi IQGAPs are differentially expressed and regulated in polarized gastric epithelial cells
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    Am J Physiol Gastrointest Liver Physiol 288:G376-87. 2005
    ..Our observations support a novel, PKC-dependent role for IQGAP1 in regulated exocytosis and suggest that IQGAP2 may play a more general role in regulating cell-cell interactions and possibly migration within the gastric mucosa...
  4. pmc Lasp1 gene disruption is linked to enhanced cell migration and tumor formation
    Han Zhang
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, Georgia, USA
    Physiol Genomics 38:372-85. 2009
    ..The striking contrast in the functional effects of loss of Lasp1 in innate cells compared with cell lines reveals distinct differences in mechanisms of motility and attachment in these models...
  5. pmc Calcium/calmodulin-dependent phosphorylation of tumor protein D52 on serine residue 136 may be mediated by CAMK2delta6
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912, USA
    Am J Physiol Gastrointest Liver Physiol 295:G1159-72. 2008
    ..The cloned, expressed protein comigrated with D52 kinase and colocalized with D52 protein in T84 and HEK293 cells. These findings support a role for CAMK2delta6 in the mediation of D52 phosphorylation...
  6. ncbi Drebrin E2 is differentially expressed and phosphorylated in parietal cells in the gastric mucosa
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Sanders R and E Bldg, Rm CB 2803, Augusta, GA, USA
    Am J Physiol Gastrointest Liver Physiol 289:G320-31. 2005
    ..Finally, the differential distribution of drebrin in parietal cells along the gland axis suggests that drebrin E2 may be an important marker of parietal cell differentiation and functionality...
  7. pmc Targeted disruption of the Lasp-1 gene is linked to increases in histamine-stimulated gastric HCl secretion
    Catherine S Chew
    Institute of Molecular Medicine and Genetics, Medical College of Georgia, Augusta, GA 30912 3175, USA
    Am J Physiol Gastrointest Liver Physiol 295:G37-G44. 2008
    ..We speculate that cAMP-dependent phosphorylation of Lasp-1 alters interactions with F-actin and/or endocytic proteins that interact with Lasp-1, thereby regulating the trafficking/activation of the H+, K+-ATPase (proton pump)...
  8. ncbi Gene expression profiling of gastrin target genes in parietal cells
    Renu N Jain
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109 0622, USA
    Physiol Genomics 24:124-32. 2006
    ..The differentially expressed genes included several genes in signaling pathways, with a substantial number (20%) known to be target genes for Wnt and Myc...
  9. pmc Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice
    Renu N Jain
    Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan 48109 2200, USA
    J Clin Invest 118:2459-70. 2008
    ..Taken together, these studies demonstrate that Hip1r plays a significant role in gastric physiology, mucosal architecture, and secretory membrane dynamics in parietal cells...
  10. ncbi Parietal cell hyperstimulation and autoimmune gastritis in cholera toxin transgenic mice
    Lymari Lopez-Diaz
    Department of Molecular and Integrative Physiology, University of Michigan, 7761 Medical Science II Building, Ann Arbor, MI 48109, USA
    Am J Physiol Gastrointest Liver Physiol 290:G970-9. 2006
    ..High Ctox in parietal cells can also induce progressive changes in the cellular architecture of the gastric glands, corresponding to the development of anti-parietal cell antibodies and autoimmune gastritis...
  11. pmc AP-1 differentially expressed proteins Krp1 and fibronectin cooperatively enhance Rho-ROCK-independent mesenchymal invasion by altering the function, localization, and activity of nondifferentially expressed proteins
    Heather J Spence
    Invasion and Metastasis Laboratory, Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, United Kingdom
    Mol Cell Biol 26:1480-95. 2006
    ....