Johan Bylund

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain
    Johan Bylund
    Department of Physiology, Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Biochem Biophys Res Commun 296:677-84. 2002
  2. ncbi Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6
    Johan Bylund
    Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Arch Biochem Biophys 412:34-41. 2003
  3. ncbi Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes
    Debebe Gebremedhin
    Department of Physiology and Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee 53226, USA
    J Neurosci 23:1678-87. 2003
  4. ncbi IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells
    Donald J Davidson
    Child and Family Research Institute and Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
    J Immunol 177:8202-11. 2006
  5. ncbi On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens
    Katarina Stark
    Department of Pharmaceutical Biosciences, Division of Biochemical Pharmacology, Uppsala University, Uppsala Biomedical Center, P O Box 591, SE 75124 Uppsala, Sweden
    Prostaglandins Other Lipid Mediat 75:47-64. 2005
  6. ncbi Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils
    Johan Bylund
    Department of Rheumatology and Inflammation Research, University of Goteborg, Sweden
    BMC Cell Biol 5:21. 2004
  7. ncbi Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy
    Huamei Fu
    The Phagocyte Research Laboratory, Department for Rheumatology and Inflammation Research, University of Goteborg, Goteborg, Sweden
    Antimicrob Agents Chemother 47:2545-50. 2003
  8. ncbi Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium
    Johan Bylund
    Department of Rheumatology and Inflammation Research, , Guldhedsgatan 10, , Sweden
    J Biol Chem 278:30578-86. 2003
  9. ncbi NADPH-oxidase activation in murine neutrophils via formyl peptide receptors
    Johan Bylund
    Department of Rheumatology and Inflammation Research, Goteborg University, Sweden
    Exp Cell Res 282:70-7. 2003
  10. ncbi Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1
    Lena Björkman
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Leukoc Biol 83:245-53. 2008

Collaborators

  • David R Harder
  • Richard J Roman
  • E H Oliw
  • RAYMOND CHARLES KOEHLER
  • Huamei Fu
  • Lena Björkman
  • Donald J Davidson
  • Claes Dahlgren
  • Katarina Stark
  • Debebe Gebremedhin
  • Anna Karlsson
  • Jennie Karlsson
  • Francois Boulay
  • Marie Josephe Rabiet
  • Rebecca S Devon
  • Kelly L Brown
  • Andrew J Currie
  • Rebecca C Ma
  • Jean Laurent Casanova
  • David P Speert
  • Capucine Picard
  • Robert E W Hancock
  • Stuart E Turvey
  • Jean-Laurent Casanova
  • Carrie M Rosenberger
  • Anne Puel
  • Paul A Campsall
  • Dawn M E Bowdish
  • Göran Sahlén
  • Hans Torma
  • Chenyang Zhang
  • Ken Yamaura

Detail Information

Publications10

  1. ncbi Identification of a novel cytochrome P450, CYP4X1, with unique localization specific to the brain
    Johan Bylund
    Department of Physiology, Cardiovascular Center, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Biochem Biophys Res Commun 296:677-84. 2002
    ..The catalytic properties and physiological function of CYP4X1 are currently under investigation...
  2. ncbi Leukotriene B4 omega-side chain hydroxylation by CYP4F5 and CYP4F6
    Johan Bylund
    Department of Physiology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Arch Biochem Biophys 412:34-41. 2003
    ..CYP4F5 and CYP4F6, due to their capacities to metabolize LTB(4), may play important roles in modulating inflammatory response in these organs...
  3. ncbi Metabotropic glutamate receptor activation enhances the activities of two types of Ca2+-activated k+ channels in rat hippocampal astrocytes
    Debebe Gebremedhin
    Department of Physiology and Cardiovascular Research Center, Medical College of Wisconsin, Milwaukee 53226, USA
    J Neurosci 23:1678-87. 2003
    ....
  4. ncbi IRAK-4 mutation (Q293X): rapid detection and characterization of defective post-transcriptional TLR/IL-1R responses in human myeloid and non-myeloid cells
    Donald J Davidson
    Child and Family Research Institute and Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC, Canada
    J Immunol 177:8202-11. 2006
    ....
  5. ncbi On the mechanism of biosynthesis of 19-hydroxyprostaglandins of human seminal fluid and expression of cyclooxygenase-2, PGH 19-hydroxylase (CYP4F8) and microsomal PGE synthase-1 in seminal vesicles and vas deferens
    Katarina Stark
    Department of Pharmaceutical Biosciences, Division of Biochemical Pharmacology, Uppsala University, Uppsala Biomedical Center, P O Box 591, SE 75124 Uppsala, Sweden
    Prostaglandins Other Lipid Mediat 75:47-64. 2005
    ..Recombinant CYP4F8 was also found to catalyze n-2 hydroxylation of PGI2 and carbaprostacyclin (Km to approximately 40 microM), and n-2 and n-3 hydroxylation of carbocyclic TXA2...
  6. ncbi Cytochalasin B triggers a novel pertussis toxin sensitive pathway in TNF-alpha primed neutrophils
    Johan Bylund
    Department of Rheumatology and Inflammation Research, University of Goteborg, Sweden
    BMC Cell Biol 5:21. 2004
    ..The receptor uncoupling results in respiratory burst activity when signals generated by reactivated formyl peptide receptors trigger the NADPH-oxidase to produce superoxide anions...
  7. ncbi Subinhibitory concentrations of the deformylase inhibitor actinonin increase bacterial release of neutrophil-activating peptides: a new approach to antimicrobial chemotherapy
    Huamei Fu
    The Phagocyte Research Laboratory, Department for Rheumatology and Inflammation Research, University of Goteborg, Goteborg, Sweden
    Antimicrob Agents Chemother 47:2545-50. 2003
    ..These findings could be potentially used as a new approach to antibacterial chemotherapy...
  8. ncbi Reactivation of formyl peptide receptors triggers the neutrophil NADPH-oxidase but not a transient rise in intracellular calcium
    Johan Bylund
    Department of Rheumatology and Inflammation Research, , Guldhedsgatan 10, , Sweden
    J Biol Chem 278:30578-86. 2003
    ..Further, phosphatidylinositol 3-kinase, mitogen-activated protein kinase, and MEK all participated in the generation of second messengers from the reactivated receptors...
  9. ncbi NADPH-oxidase activation in murine neutrophils via formyl peptide receptors
    Johan Bylund
    Department of Rheumatology and Inflammation Research, Goteborg University, Sweden
    Exp Cell Res 282:70-7. 2003
    ..Finally, we show that a synthetic hexapeptide, WKYMVM, is a more potent stimulus than fMLF for murine neutrophils and that these two agonists probably act via nonidentical high-affinity receptors...
  10. ncbi Serum amyloid A mediates human neutrophil production of reactive oxygen species through a receptor independent of formyl peptide receptor like-1
    Lena Björkman
    Department of Rheumatology and Inflammation Research, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Leukoc Biol 83:245-53. 2008
    ..Future identification and characterization of the SAA receptor could lead to development of novel, therapeutic targets for treatment of RA...