J A Bosso

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. pmc Relationship between vancomycin trough concentrations and nephrotoxicity: a prospective multicenter trial
    John A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Charleston and Columbia, South Carolina 29425, USA
    Antimicrob Agents Chemother 55:5475-9. 2011
  2. doi The association between antibiotic use and resistance: the role of secondary antibiotics
    J A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy MUSC campus, MSC 140, Charleston, SC 29425, USA
    Eur J Clin Microbiol Infect Dis 29:1125-9. 2010
  3. ncbi Consequences of combining cystic fibrosis- and non-cystic fibrosis-derived Pseudomonas aeruginosa antibiotic susceptibility results in hospital antibiograms
    John A Bosso
    Department of Pharmacy and Clinical Sciences, South Carolina College of Pharmacy, Charleston, SC 29425, USA
    Ann Pharmacother 40:1946-9. 2006
  4. pmc Using interrupted time series analysis to assess associations of fluoroquinolone formulary changes with susceptibility of gram-negative pathogens and isolation rates of methicillin-resistant Staphylococcus aureus
    John A Bosso
    Department of Pharmacy and Clinical Sciences, South Carolina College of Pharmacy, Charleston, 29425, USA
    Antimicrob Agents Chemother 50:2106-12. 2006
  5. ncbi The antimicrobial armamentarium: evaluating current and future treatment options
    John A Bosso
    South Carolina College of Pharmacy, Charleston, South Carolina 29425, USA
    Pharmacotherapy 25:55S-62S. 2005
  6. doi Application of antimicrobial stewardship to optimise management of community acquired pneumonia
    J A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Medical University of South Carolina Campus, Charleston, SC 29425, USA
    Int J Clin Pract 65:775-83. 2011
  7. pmc Linezolid pharmacokinetics in adult patients with cystic fibrosis
    John A Bosso
    Department of Pharmaceutical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Antimicrob Agents Chemother 48:281-4. 2004
  8. pmc Benchmarking in academic pharmacy departments
    John A Bosso
    South Carolina College of Pharmacy Charleston, SC, USA
    Am J Pharm Educ 74:140. 2010
  9. ncbi Assessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient-care areas
    R L White
    Medical University of South Carolina, College of Pharmacy, Anti Infective Research Laboratory, Charleston, SC, 29425, USA
    Clin Infect Dis 31:16-23. 2000
  10. doi Analysis of an outbreak of Clostridium difficile infection controlled with enhanced infection control measures
    Cassandra D Salgado
    Department of Medicine, Division of Infectious Diseases, Medical University of South Carolina, 135 Rutledge Avenue, 12th Floor RT, Suite 1204, Charleston, SC 29425, USA
    Am J Infect Control 37:458-64. 2009

Collaborators

Detail Information

Publications21

  1. pmc Relationship between vancomycin trough concentrations and nephrotoxicity: a prospective multicenter trial
    John A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Charleston and Columbia, South Carolina 29425, USA
    Antimicrob Agents Chemother 55:5475-9. 2011
    ..Vancomycin trough concentrations of >15 mg/ml appear to be associated with a 3-fold increased risk of nephrotoxicity...
  2. doi The association between antibiotic use and resistance: the role of secondary antibiotics
    J A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy MUSC campus, MSC 140, Charleston, SC 29425, USA
    Eur J Clin Microbiol Infect Dis 29:1125-9. 2010
    ..Thus, a resistance problem may not be adequately addressed by simply altering the utilization of the primary antibiotic...
  3. ncbi Consequences of combining cystic fibrosis- and non-cystic fibrosis-derived Pseudomonas aeruginosa antibiotic susceptibility results in hospital antibiograms
    John A Bosso
    Department of Pharmacy and Clinical Sciences, South Carolina College of Pharmacy, Charleston, SC 29425, USA
    Ann Pharmacother 40:1946-9. 2006
    ..If results from patients with known resistance patterns that vary from normal are included, the overall susceptibility value for the institution could be misleadingly skewed...
  4. pmc Using interrupted time series analysis to assess associations of fluoroquinolone formulary changes with susceptibility of gram-negative pathogens and isolation rates of methicillin-resistant Staphylococcus aureus
    John A Bosso
    Department of Pharmacy and Clinical Sciences, South Carolina College of Pharmacy, Charleston, 29425, USA
    Antimicrob Agents Chemother 50:2106-12. 2006
    ..These findings suggest that potential changes in susceptibility to fluoroquinolones and isolation of MRSA may vary by both drug and organism...
  5. ncbi The antimicrobial armamentarium: evaluating current and future treatment options
    John A Bosso
    South Carolina College of Pharmacy, Charleston, South Carolina 29425, USA
    Pharmacotherapy 25:55S-62S. 2005
    ..Antimicrobial agents in the pipeline with marked gram-positive activity include dalbavancin, telavancin, and oritavancin...
  6. doi Application of antimicrobial stewardship to optimise management of community acquired pneumonia
    J A Bosso
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Medical University of South Carolina Campus, Charleston, SC 29425, USA
    Int J Clin Pract 65:775-83. 2011
    ..Adherence to evidence-based guidelines can have a profound and positive impact on patient outcomes and healthcare costs...
  7. pmc Linezolid pharmacokinetics in adult patients with cystic fibrosis
    John A Bosso
    Department of Pharmaceutical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Antimicrob Agents Chemother 48:281-4. 2004
    ..Patients with inadequate clinical responses to linezolid may require more frequent dosing...
  8. pmc Benchmarking in academic pharmacy departments
    John A Bosso
    South Carolina College of Pharmacy Charleston, SC, USA
    Am J Pharm Educ 74:140. 2010
    ..To date, attempts to gather this data have had limited success. We believe this information is potentially important, urge that efforts to gather it should be continued, and offer suggestions to achieve full participation...
  9. ncbi Assessment of the relationship between antimicrobial usage and susceptibility: differences between the hospital and specific patient-care areas
    R L White
    Medical University of South Carolina, College of Pharmacy, Anti Infective Research Laboratory, Charleston, SC, 29425, USA
    Clin Infect Dis 31:16-23. 2000
    ..Surveillance should include both susceptibility and drug usage patterns in individual areas within an institution...
  10. doi Analysis of an outbreak of Clostridium difficile infection controlled with enhanced infection control measures
    Cassandra D Salgado
    Department of Medicine, Division of Infectious Diseases, Medical University of South Carolina, 135 Rutledge Avenue, 12th Floor RT, Suite 1204, Charleston, SC 29425, USA
    Am J Infect Control 37:458-64. 2009
    ..51; 95% confidence interval: 2.96-4.16) from a baseline rate of 1.35 per 1000 patient-days. We describe the outbreak, the relationship between antibiotic use and CDI, and the effect of enhanced infection control measures (EICM) on CDI...
  11. ncbi Assessment of differences in antimicrobial effect determined with two in vitro pharmacodynamic models: impact of surface area to volume ratio
    Roger L White
    Anti Infective Research Laboratories, College of Pharmacy, Medical University of South Carolina, Charleston 29425, USA
    Pharmacotherapy 23:603-8. 2003
    ..To measure the influence of different surface area:volume ratios (SA:Vs) on antibiotic penetration and subsequent antibacterial effect...
  12. ncbi Comparative activity of gatifloxacin and other antibiotics against 4009 clinical isolates of Streptococcus pneumoniae in the United States during 1999-2000
    Roger L White
    Anti Infective Research Laboratory, Medical University of South Carolina, Charleston, USA
    Diagn Microbiol Infect Dis 43:207-17. 2002
    ....
  13. pmc Determination of antibiotic effect in an in vitro pharmacodynamic model: comparison with an established animal model of infection
    Charles R Bonapace
    Anti Infective Research Laboratory, College of Pharmacy, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Antimicrob Agents Chemother 46:3574-9. 2002
    ..This study, which compares pharmacodynamic principles between an in vitro and an animal model, demonstrated similar relationships between %T>MICs and effects...
  14. ncbi Differences in antimicrobial drug exposure in patients with various degrees of renal function based on recommendations from dosing references
    Charles R Bonapace
    Anti Infective Research Laboratory, College of Pharmacy, Medical University of South Carolina, Charleston 29425, USA
    Pharmacotherapy 22:1097-104. 2002
    ..To calculate and compare 24-hour area under the unbound drug concentration-time curves (AUC(0-24)) of antimicrobials with dosing recommendations from six commonly used dosing references...
  15. doi Nosocomial infections due to methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococcus: relationships with antibiotic use and cost drivers
    Patrick D Mauldin
    Department of Clinical Pharmacy and Outcome Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC 29425, USA
    Ann Pharmacother 42:317-26. 2008
    ....
  16. ncbi Comparison of methods of interpretation of checkerboard synergy testing
    Charles R Bonapace
    Anti Infective Research Laboratory, College of Pharmacy, Medical University of South Carolina, Charleston, SC, USA
    Diagn Microbiol Infect Dis 44:363-6. 2002
    ..As interpretations were found to vary widely based upon method, one should be aware of this in interpreting the relevant literature...
  17. ncbi Comparative in vitro pharmacodynamics of imipenem and meropenem against ATCC strains of Escherichia coli, Staphylococcus aureus and Bacteroides fragilis
    R L White
    Anti Infective Research Laboratory, College of Pharmacy, Medical University of South Carolina, QF 219, 280 Calhoun Street, P O Box 250142, Charleston, South Carolina 29425, USA
    Diagn Microbiol Infect Dis 39:39-47. 2001
    ..response, when normalized by the MIC and corrected for drug degradation, these agents displayed similar pharmacodynamic parameter-response relationships...
  18. pmc Attributable hospital cost and length of stay associated with health care-associated infections caused by antibiotic-resistant gram-negative bacteria
    Patrick D Mauldin
    Department of Clinical Pharmacy and Outcome Sciences, South Carolina College of Pharmacy, Charleston, SC 29425, USA
    Antimicrob Agents Chemother 54:109-15. 2010
    ..This information should be used to assess the potential cost-efficacy of interventions aimed at the prevention of such infections...
  19. ncbi A novel method of estimating cost of therapy by using patient population characteristics: analysis of fluoroquinolones in various populations with different distributions of renal function
    Kevin A Enzweiler
    Anti Infective Research Laboratory, College of Pharmacy, Medical University of South Carolina, Charleston 29425, USA
    Pharmacotherapy 23:925-32. 2003
    ..For example, the cost implications of using manufacturers' recommendations for dosing in patients with renal dysfunction may be important, depending on the distribution of various levels of renal function within a patient population...
  20. ncbi Compatibility of filgrastim with selected antimicrobial drugs during simulated Y-site administration
    P D Hall
    College of Pharmacy, Medical University of South Carolina MUSC, Charleston 29425 2303, USA
    Am J Health Syst Pharm 54:185-9. 1997
    ..In most cases, filgrastim retained its activity in the presence of a variety of antimicrobial drugs for up to four hours; in all cases, the antimicrobial drugs remained stable...
  21. ncbi The impact of antibiotic management on resistance
    John A Bosso
    Department of Pharmacy and Clinical Sciences, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Pharmacotherapy 24:224S-31S. 2004
    ..Such studies are necessary to provide institutions with the data they need to make informed decisions regarding antibiotic use...