Heather A Bimonte-Nelson

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. ncbi request reprint Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center for Studies on Aging, Medical University of South Carolina, Charleston 29425, USA
    Exp Neurol 181:301-12. 2003
  2. ncbi request reprint Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston 29425, USA
    Behav Neurosci 117:1395-406. 2003
  3. ncbi request reprint Ovarian hormones and cognition in the aged female rat: II. progesterone supplementation reverses the cognitive enhancing effects of ovariectomy
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA
    Behav Neurosci 118:707-14. 2004
  4. ncbi request reprint Progesterone counteracts estrogen-induced increases in neurotrophins in the aged female rat brain
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center on Aging, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425
    Neuroreport 15:2659-63. 2004
  5. ncbi request reprint Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats
    Kristen L French
    Department of Cellular and Molecular Pharmacology, Medical University of South Carolina, USA
    Behav Brain Res 169:256-62. 2006
  6. pmc Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat
    Ann Charlotte Granholm
    Department of Neurosciences and the Center on Aging, Medical University of South Carolina, Charleston, SC 29425, USA
    J Alzheimers Dis 14:133-45. 2008
  7. ncbi request reprint Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen
    Christopher L Hunter
    Department of Physiology and Neuroscience and the Center on Aging, Medical University of South Carolina, 26 Bee Street, Charleston, SC 29425, USA
    Neurobiol Aging 25:873-84. 2004
  8. ncbi request reprint Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center for Studies on Aging, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
    Behav Brain Res 139:47-57. 2003
  9. ncbi request reprint ERK-mediated NGF signaling in the rat septo-hippocampal pathway diminishes with age
    Brice J Williams
    Department of Neurosciences, Center on Aging, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 188:605-18. 2006
  10. ncbi request reprint Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-alpha in the brain
    ANDREW R SAS
    Medical University of South Carolina, Department of Microbiology and Immunology, USA
    AIDS 21:2151-9. 2007

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Testosterone, but not nonaromatizable dihydrotestosterone, improves working memory and alters nerve growth factor levels in aged male rats
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center for Studies on Aging, Medical University of South Carolina, Charleston 29425, USA
    Exp Neurol 181:301-12. 2003
    ....
  2. ncbi request reprint Ovarian hormones and cognition in the aged female rat: I. Long-term, but not short-term, ovariectomy enhances spatial performance
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston 29425, USA
    Behav Neurosci 117:1395-406. 2003
    ..The hypothesis that long-term ovarian hormone loss is detrimental to spatial memory in aged rats was not supported. The authors hypothesize that removal of elevated progesterone levels is related to the ovx-induced cognitive enhancement...
  3. ncbi request reprint Ovarian hormones and cognition in the aged female rat: II. progesterone supplementation reverses the cognitive enhancing effects of ovariectomy
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, SC 29425, USA
    Behav Neurosci 118:707-14. 2004
    ..These findings may speak to studies in menopausal women which suggest that combination hormone therapies have a negative impact on cognition...
  4. ncbi request reprint Progesterone counteracts estrogen-induced increases in neurotrophins in the aged female rat brain
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center on Aging, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425
    Neuroreport 15:2659-63. 2004
    ..Our findings suggest that the aged female brain is responsive to estrogen in cognitive brain regions, and that progesterone can reverse these estrogen effects...
  5. ncbi request reprint Chronic nicotine improves working and reference memory performance and reduces hippocampal NGF in aged female rats
    Kristen L French
    Department of Cellular and Molecular Pharmacology, Medical University of South Carolina, USA
    Behav Brain Res 169:256-62. 2006
    ..The effects of nicotine on hippocampal NGF levels are discussed as a potential mechanism of nicotine-induced improvements in working and reference memory...
  6. pmc Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat
    Ann Charlotte Granholm
    Department of Neurosciences and the Center on Aging, Medical University of South Carolina, Charleston, SC 29425, USA
    J Alzheimers Dis 14:133-45. 2008
    ..These data suggest that saturated fat, hydrogenated fat and cholesterol can profoundly impair memory and hippocampal morphology...
  7. ncbi request reprint Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen
    Christopher L Hunter
    Department of Physiology and Neuroscience and the Center on Aging, Medical University of South Carolina, 26 Bee Street, Charleston, SC 29425, USA
    Neurobiol Aging 25:873-84. 2004
    ..These findings further support Ts65Dn mice as a model for specific AD-like symptoms, and demonstrate that estrogen treatment of this type does not improve the cognitive ability of male Ts65Dn mice...
  8. ncbi request reprint Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
    Heather A Bimonte-Nelson
    Department of Physiology and Neuroscience and the Center for Studies on Aging, Medical University of South Carolina, 173 Ashley Avenue, Charleston, SC 29425, USA
    Behav Brain Res 139:47-57. 2003
    ....
  9. ncbi request reprint ERK-mediated NGF signaling in the rat septo-hippocampal pathway diminishes with age
    Brice J Williams
    Department of Neurosciences, Center on Aging, Charleston, SC 29425, USA
    Psychopharmacology (Berl) 188:605-18. 2006
    ..This degeneration may be a result of disrupted nerve growth factor (NGF) signaling. Aged rats have memory deficits, BFCN degeneration, and disrupted NGF signaling...
  10. ncbi request reprint Cognitive dysfunction in HIV encephalitic SCID mice correlates with levels of Interferon-alpha in the brain
    ANDREW R SAS
    Medical University of South Carolina, Department of Microbiology and Immunology, USA
    AIDS 21:2151-9. 2007
    ..Interferon alpha (IFNalpha) is an antiviral cytokine produced in response to viral infection. IFNalpha also acts as a neuromodulatory molecule in the central nervous system (CNS). Elevated IFNalpha in the CNS causes cognitive deficits...
  11. ncbi request reprint Progesterone reverses the spatial memory enhancements initiated by tonic and cyclic oestrogen therapy in middle-aged ovariectomized female rats
    Heather A Bimonte-Nelson
    Department of Psychology, Arizona State University, PO Box 871104, Tempe, AZ 85287, USA
    Eur J Neurosci 24:229-42. 2006
    ..Further, there appears to be a dissociation between HT effects on cognition and mortality rates...
  12. pmc Patterns of neurotrophin protein levels in male and female Fischer 344 rats from adulthood to senescence: how young is "young" and how old is "old"?
    Heather A Bimonte-Nelson
    Department of Psychology, Behavioral Neuroscience Division, Arizona State University, Tempe, Arizona 85287, USA
    Exp Aging Res 34:13-26. 2008
    ..The current findings suggest that profound changes in neurotrophin protein levels can occur within only a few months time, and that these changes influence whether age-related neurotrophin alterations are realized...
  13. pmc Higher levels of estradiol replacement correlate with better spatial memory in surgically menopausal young and middle-aged rats
    Joshua S Talboom
    Department of Psychology, Arizona State University, Behavioral Neuroscience Division, P O Box 871104, Tempe, AZ 85287, USA
    Neurobiol Learn Mem 90:155-63. 2008
    ..Further, there appears to be a distinction between sensitivity to Ovx and responsiveness to ET after Ovx for spatial reference memory performance...