Martin W Bienengraeber

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. pmc Quantitative characterization of changes in the cardiac mitochondrial proteome during anesthetic preconditioning and ischemia
    Martin Bienengraeber
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 45:163-70. 2013
  2. pmc KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy
    Vasiliki Zoga
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Pain 6:6. 2010
  3. ncbi request reprint Cardioprotection by volatile anesthetics
    Martin W Bienengraeber
    Department of Anesthesiology, Pharmacology and Toxicology, Division of Cardiovascular Diseases, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Vascul Pharmacol 42:243-52. 2005
  4. ncbi request reprint Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium
    Pascal C Chiari
    Division of Cardiovascular Diseases, Department of Anesthesiology, The Medical College of Wisconsin, Milwaukee 53226, USA
    Anesthesiology 103:74-83. 2005
  5. pmc Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning
    Julien Amour
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 110:317-25. 2009
  6. pmc Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activity
    Yasushi Mio
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 108:612-20. 2008
  7. ncbi request reprint Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression
    Marina Jamnicki-Abegg
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 103:1006-14. 2005
  8. ncbi request reprint Cardioprotection by volatile anesthetics: new applications for old drugs?
    Phillip F Pratt
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Curr Opin Anaesthesiol 19:397-403. 2006
  9. pmc The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel
    Tina C Wan
    Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 324:234-43. 2008
  10. ncbi request reprint Volatile anesthetic-induced cardiac preconditioning
    Anna Stadnicka
    Department of Anesthesiology, Medical College of Wisconsin, MEB M4280, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    J Anesth 21:212-9. 2007

Research Grants

Collaborators

Detail Information

Publications12

  1. pmc Quantitative characterization of changes in the cardiac mitochondrial proteome during anesthetic preconditioning and ischemia
    Martin Bienengraeber
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Physiol Genomics 45:163-70. 2013
    ..Thus, a proteomic mass spectral approach does not only assess quantitative changes without prior knowledge of proteins, but also allows insight into the mechanisms of ischemia and reperfusion injury and APC...
  2. pmc KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy
    Vasiliki Zoga
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Mol Pain 6:6. 2010
    ....
  3. ncbi request reprint Cardioprotection by volatile anesthetics
    Martin W Bienengraeber
    Department of Anesthesiology, Pharmacology and Toxicology, Division of Cardiovascular Diseases, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    Vascul Pharmacol 42:243-52. 2005
    ..This review summarizes some of the recent major developments in the understanding of cardioprotection by volatile anesthetics...
  4. ncbi request reprint Role of endothelial nitric oxide synthase as a trigger and mediator of isoflurane-induced delayed preconditioning in rabbit myocardium
    Pascal C Chiari
    Division of Cardiovascular Diseases, Department of Anesthesiology, The Medical College of Wisconsin, Milwaukee 53226, USA
    Anesthesiology 103:74-83. 2005
    ..Isoflurane produces delayed preconditioning in vivo. The authors tested the hypothesis that endothelial, inducible, or neuronal nitric oxide synthase (NOS) is a trigger or mediator of this protective effect...
  5. pmc Role of heat shock protein 90 and endothelial nitric oxide synthase during early anesthetic and ischemic preconditioning
    Julien Amour
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 110:317-25. 2009
    ..Heat shock protein 90 (Hsp90) regulates endothelial nitric oxide synthase (eNOS) activity. In this study, the authors tested the hypothesis that Hsp90-eNOS interactions modulate APC and IPC...
  6. pmc Age-related attenuation of isoflurane preconditioning in human atrial cardiomyocytes: roles for mitochondrial respiration and sarcolemmal adenosine triphosphate-sensitive potassium channel activity
    Yasushi Mio
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 108:612-20. 2008
    ..Here, the impact of age on the role of two major effectors of APC, mitochondria and sarcolemmal adenosine triphosphate-sensitive potassium (sarcKATP) channels, in preconditioning of the human atrial myocardium were investigated...
  7. ncbi request reprint Isoflurane inhibits cardiac myocyte apoptosis during oxidative and inflammatory stress by activating Akt and enhancing Bcl-2 expression
    Marina Jamnicki-Abegg
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Anesthesiology 103:1006-14. 2005
    ..The underlying mechanisms remain undefined. The authors tested whether isoflurane reduces apoptosis in cardiomyocytes subjected to oxidative or inflammatory stress by enhancing Akt and B-cell lymphoma-2 (Bcl-2)...
  8. ncbi request reprint Cardioprotection by volatile anesthetics: new applications for old drugs?
    Phillip F Pratt
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Curr Opin Anaesthesiol 19:397-403. 2006
    ..This review will update and integrate these recent data into the current mechanistic model of anesthetic-induced preconditioning...
  9. pmc The A3 adenosine receptor agonist CP-532,903 [N6-(2,5-dichlorobenzyl)-3'-aminoadenosine-5'-N-methylcarboxamide] protects against myocardial ischemia/reperfusion injury via the sarcolemmal ATP-sensitive potassium channel
    Tina C Wan
    Department of Pharmacology and Toxicology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Pharmacol Exp Ther 324:234-43. 2008
    ..We conclude that CP-532,903 is a highly selective agonist of the mouse A(3)AR that protects against ischemia/reperfusion injury by activating sarcolemmal K(ATP) channels...
  10. ncbi request reprint Volatile anesthetic-induced cardiac preconditioning
    Anna Stadnicka
    Department of Anesthesiology, Medical College of Wisconsin, MEB M4280, 8701 Watertown Plank Road, Milwaukee, Wisconsin 53226, USA
    J Anesth 21:212-9. 2007
    ..Moreover, the article addresses current concepts and controversies regarding the specific roles of the mitochondrial and the sarcolemmal K(ATP) channels in APC...
  11. ncbi request reprint Isoflurane protects against myocardial infarction during early reperfusion by activation of phosphatidylinositol-3-kinase signal transduction: evidence for anesthetic-induced postconditioning in rabbits
    Pascal C Chiari
    Departments of Anesthesiology, Division of Cardiovascular Diseases, The Medical College of Wisconsin, the Clement J Zablocki Veterans Affairs Medical Center, Milwaukee, Wisconsin, USA
    Anesthesiology 102:102-9. 2005
    ..The authors tested the hypothesis that isoflurane produces cardioprotection during early reperfusion after myocardial ischemia by a PI3K-dependent mechanism...
  12. pmc Partial restoration of the long QT syndrome associated KCNQ1 A341V mutant by the KCNE1 β-subunit
    Ikuomi Mikuni
    Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Biochim Biophys Acta 1810:1285-93. 2011
    ..We investigated the biophysical characteristics of A341V in a cardiac environment by utilizing a cardiac cell line, and in particular the impact of the KCNE1 β-subunit...

Research Grants1

  1. Mechanisms of photobiomodulation in myocardial reperfusion injury
    Phillip F Pratt; Fiscal Year: 2010
    ..Near infrared light, alone or in combination with other pharmacological adjuvants could offer a unique strategy to mitigate the damage that occurs to the ischemic myocardium during reperfusion of the coronary artery. ..