Jan N Basile

Summary

Affiliation: Medical University of South Carolina
Country: USA

Publications

  1. doi request reprint Identifying and managing factors that interfere with or worsen blood pressure control
    Jan N Basile
    Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, SC 29414, USA
    Postgrad Med 122:35-48. 2010
  2. doi request reprint The potential of sodium glucose cotransporter 2 (SGLT2) inhibitors to reduce cardiovascular risk in patients with type 2 diabetes (T2DM)
    Jan N Basile
    Seinsheimer Cardiovascular Health Program, Medical University of South Carolina, Charleston, SC 29425, USA
    J Diabetes Complications 27:280-6. 2013
  3. doi request reprint A new approach to glucose control in type 2 diabetes: the role of kidney sodium-glucose co-transporter 2 inhibition
    Jan Basile
    Seinsheimer Cardiovascular Health Program, Medical University of South Carolina, Ralph H Johnson VA Medical Center, Charleston, SC 29403, USA
    Postgrad Med 123:38-45. 2011
  4. doi request reprint Comparison of aliskiren/hydrochlorothiazide combination therapy with hydrochlorothiazide monotherapy in older patients with stage 2 systolic hypertension: results of the ACTION study
    Jan Basile
    Ralph H Johnson VA Medical Center and Medical University of South Carolina, Charleston, SC 29401, USA
    J Clin Hypertens (Greenwich) 13:162-9. 2011
  5. doi request reprint One size does not fit all: the role of vasodilating beta-blockers in controlling hypertension as a means of reducing cardiovascular and stroke risk
    Jan N Basile
    College of Medicine, Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, South Carolina 29425 0950, USA
    Am J Med 123:S9-15. 2010
  6. ncbi request reprint A statewide primary care approach to cardiovascular risk factor control in high-risk diabetic and nondiabetic patients with hypertension
    Jan N Basile
    Department of Medicine, Medical University of South Carolina, Charleston, SC and the Ralph H Johnson VA Medical Center, Charleston, SC 29401 5703, USA
    J Clin Hypertens (Greenwich) 6:18-25. 2004
  7. ncbi request reprint Analysis of recent papers in hypertension
    Jan N Basile
    Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston, SC 29403, USA
    J Clin Hypertens (Greenwich) 6:96-101. 2004
  8. doi request reprint Rationale for fixed-dose combination therapy to reach lower blood pressure goals
    Jan N Basile
    Primary Care Service Line, Ralph H Johnson VA Medical Center, and Medical University of South Carolina, Charleston, South Carolina 29403, USA
    South Med J 101:918-24. 2008
  9. doi request reprint Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Hypertens 22:792-801. 2009
  10. ncbi request reprint Systolic blood pressure elevation: it's where the action is
    Jan N Basile
    Primary Care Program, and Division of General Internal Medicine Geriatrics, Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston, South Carolina 29403, USA
    Drugs Aging 20:287-8. 2003

Detail Information

Publications23

  1. doi request reprint Identifying and managing factors that interfere with or worsen blood pressure control
    Jan N Basile
    Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, SC 29414, USA
    Postgrad Med 122:35-48. 2010
    ..In the face of worsening BP control, clinicians must actively investigate potential contributing factors and appropriately increase or adjust antihypertensive therapy...
  2. doi request reprint The potential of sodium glucose cotransporter 2 (SGLT2) inhibitors to reduce cardiovascular risk in patients with type 2 diabetes (T2DM)
    Jan N Basile
    Seinsheimer Cardiovascular Health Program, Medical University of South Carolina, Charleston, SC 29425, USA
    J Diabetes Complications 27:280-6. 2013
    ..The results of clinical trials of SGLT2 inhibitors are summarized and discussed...
  3. doi request reprint A new approach to glucose control in type 2 diabetes: the role of kidney sodium-glucose co-transporter 2 inhibition
    Jan Basile
    Seinsheimer Cardiovascular Health Program, Medical University of South Carolina, Ralph H Johnson VA Medical Center, Charleston, SC 29403, USA
    Postgrad Med 123:38-45. 2011
    ..Initial clinical data are promising and suggest that SGLT2 inhibitors may be a new therapeutic option for treating type 2 diabetes mellitus...
  4. doi request reprint Comparison of aliskiren/hydrochlorothiazide combination therapy with hydrochlorothiazide monotherapy in older patients with stage 2 systolic hypertension: results of the ACTION study
    Jan Basile
    Ralph H Johnson VA Medical Center and Medical University of South Carolina, Charleston, SC 29401, USA
    J Clin Hypertens (Greenwich) 13:162-9. 2011
    ..1% vs 33.3%). Aliskiren/HCTZ therapy provides substantial BP reductions and may thus be a useful treatment option for older patients with stage 2 hypertension...
  5. doi request reprint One size does not fit all: the role of vasodilating beta-blockers in controlling hypertension as a means of reducing cardiovascular and stroke risk
    Jan N Basile
    College of Medicine, Medical University of South Carolina and Ralph H Johnson VA Medical Center, Charleston, South Carolina 29425 0950, USA
    Am J Med 123:S9-15. 2010
    ....
  6. ncbi request reprint A statewide primary care approach to cardiovascular risk factor control in high-risk diabetic and nondiabetic patients with hypertension
    Jan N Basile
    Department of Medicine, Medical University of South Carolina, Charleston, SC and the Ralph H Johnson VA Medical Center, Charleston, SC 29401 5703, USA
    J Clin Hypertens (Greenwich) 6:18-25. 2004
    ..These findings confirm the low rates of multiple risk factor control and highlight challenges of reaching evidence-based goals in primary care...
  7. ncbi request reprint Analysis of recent papers in hypertension
    Jan N Basile
    Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston, SC 29403, USA
    J Clin Hypertens (Greenwich) 6:96-101. 2004
  8. doi request reprint Rationale for fixed-dose combination therapy to reach lower blood pressure goals
    Jan N Basile
    Primary Care Service Line, Ralph H Johnson VA Medical Center, and Medical University of South Carolina, Charleston, South Carolina 29403, USA
    South Med J 101:918-24. 2008
    ..Several clinical trials are under way to further determine the risks and benefits of lowering blood pressure beyond the currently recommended threshold...
  9. doi request reprint Plasma Renin test-guided drug treatment algorithm for correcting patients with treated but uncontrolled hypertension: a randomized controlled trial
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Hypertens 22:792-801. 2009
    ..65 ng/ml/h) indicates sodium-volume excess "V" hypertension, whereas values >or=0.65 indicate renin-angiotensin vasoconstriction excess "R" hypertension...
  10. ncbi request reprint Systolic blood pressure elevation: it's where the action is
    Jan N Basile
    Primary Care Program, and Division of General Internal Medicine Geriatrics, Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston, South Carolina 29403, USA
    Drugs Aging 20:287-8. 2003
  11. doi request reprint Beta-blockers for treatment of hypertension
    Jan N Basile
    Ralph H Johnson VA Medical Center, 109 Bee St, Charleston, SC 29401, USA
    Postgrad Med 114:11-7. 2003
    ..Because beta-blockers offer unique cardiovascular protection, they should be considered an integral part of the treatment regimen for patients with hypertension who are at risk for cardiovascular events...
  12. ncbi request reprint Hypertension curriculum review. The importance of systolic blood pressure elevation in elderly persons
    Donald G Vidt
    Ralph H Johnson VA Medical Center, 109 Bee Street, Charleston, SC 29401, USA
    J Clin Hypertens (Greenwich) 6:461-5. 2004
  13. ncbi request reprint Controlling blood pressure in 50% of all hypertensive patients: an achievable goal in the healthy people 2010 report?
    Brent M Egan
    Department of Medicine, Division of General Internal Medicine, Geriatrics and Hypertension, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    J Investig Med 51:373-85. 2003
    ..In the absence of a coordinated strategic plan, achieving this critically important goal for BP control is highly unlikely...
  14. ncbi request reprint Halting the progression of heart failure: finding the optimal combination therapy
    Jan N Basile
    Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston 29403, USA
    Cleve Clin J Med 69:104-5, 109-10, 112. 2002
    ..For most patients, treating heart failure involves correcting underlying left ventricular dysfunction, thereby slowing the remodeling process...
  15. ncbi request reprint Most antihypertensives have similar efficacy and safety: a meta-analysis
    Jan N Basile
    Ralph H Johnson VA Medical Center, 1090 Bee Street, Charleston, SC 29403, USA
    J Clin Hypertens (Greenwich) 4:50-1. 2002
  16. ncbi request reprint Clinical considerations and practical recommendations for the primary care practitioner in the management of anemia of chronic kidney disease
    Jan N Basile
    Ralph H Johnson VA Medical Center and the Medical University of South Carolina, Charleston, South Carolina 29401, USA
    South Med J 100:1200-7. 2007
    ..This report describes anemia in CKD and its association with diabetes, cardiovascular disease, and poor disease outcome, and offers suggestions for the recognition and treatment of anemia of CKD in the primary care setting...
  17. ncbi request reprint Blood pressure reduction in those with cerebrovascular disease prevents secondary stroke
    Jan N Basile
    Ralph H Johnson VA Medical Center, 1090 Bee Street, Charleston, SC 29403, USA
    J Clin Hypertens (Greenwich) 4:47-8. 2002
  18. ncbi request reprint American Society of Hypertension regional chapters: leveraging the impact of the clinical hypertension specialist in the local community
    Brent M Egan
    Department of Medicine, Medical University of South Carolina, Charleston 29425, USA
    Am J Hypertens 15:372-9. 2002
    ....
  19. ncbi request reprint Titration of beta-blockers in heart failure. How to maximize benefit while minimizing adverse events
    Jan N Basile
    Ralph H Johnson VA Medical Center, Medical University of South Carolina, Charleston, USA
    Postgrad Med 113:63-70; quiz 3. 2003
    ..Currently, professional treatment guidelines recommend beta-blocker therapy in combination with ACE inhibitors an diuretics as the standard of care in the treatment of heart failure...
  20. ncbi request reprint Optimizing antihypertensive treatment in clinical practice
    Jan N Basile
    Ralph H Johnson VA Medical Center, Department of Medicine, Division of General Internal Medicine Geriatrics, Medical University of South Carolina, 109 Bee Street, Charleston, SC 29401, USA
    Am J Hypertens 16:13S-17S. 2003
    ..This article explores the cardioprotective role of how betaB may be used to optimize antihypertensive treatment...
  21. ncbi request reprint Recognizing the link between CKD and CVD in the primary care setting: accurate and early diagnosis for timely and appropriate intervention
    Jan N Basile
    Ralph H Johnson VA Medical Center, Medical University of South Carolina, 109 Bee Street, Charleston, SC 29401, USA
    South Med J 100:499-505. 2007
    ..This report describes the major risk factors and comorbidities associated with the development and progression of CKD and offers suggestions for timely diagnosis and management of CKD in the primary care setting...
  22. ncbi request reprint ACE inhibitor-associated cough lessened with iron supplementation
    Jan N Basile
    Ralph H Johnson VA Medical Center, 1090 Bee Street, Charleston, SC 29403, USA
    J Clin Hypertens (Greenwich) 4:49-50. 2002
  23. ncbi request reprint A historical look at hypertension: celebrating 100 years with the Southern Medical Association
    Jan N Basile
    Primary Care Service Line, Ralph H Johnson VA Medical Center, 109 Bee Street, Charleston, SC 29401, USA
    South Med J 99:1412-3. 2006