Research Topics
Genomes and Genes | Russell BarkleySummaryAffiliation: Medical University of South Carolina Country: USA Publications
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Publications
Young adult follow-up of hyperactive children: antisocial activities and drug useRussell A Barkley
Department of Health Professions, College of Health Professions, Medical University of South Carolina, Charleston 29425, USA
J Child Psychol Psychiatry 45:195-211. 2004..Hyperactive/ADHD children are believed to be a greater risk for adolescent and young adult antisocial activity and drug use/abuse, particularly that subset having comorbid conduct problems/disorder...
Does the treatment of attention-deficit/hyperactivity disorder with stimulants contribute to drug use/abuse? A 13-year prospective studyRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical School, Worcester, Massachusetts, USA
Pediatrics 111:97-109. 2003..To examine the impact of stimulant treatment during childhood and high school on risk for substance use, dependence, and abuse by young adulthood...
Driving impairments in teens and adults with attention-deficit/hyperactivity disorderRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Harborview Office Tower, 19 Hagood Avenue, Room 910, Charleston, SC 29425, USA
Psychiatr Clin North Am 27:233-60. 2004....
Issues in the diagnosis of attention-deficit/hyperactivity disorder in childrenRussell A Barkley
College of Health Professions, Medical University of South Carolina, Charleston, SC 29401, USA
Brain Dev 25:77-83. 2003..Clinicians should be aware of these problems and the adjustments that need to be made to them when dealing with special populations that were not represented in the field trials used to develop these criteria...
Identification and characterization of human NR4A2 polymorphisms in attention deficit hyperactivity disorderKAREN MULLER SMITH
Genetics Program, Sackler School of GBS, Tufts University, Boston, Massachusetts, USA
Am J Med Genet B Neuropsychiatr Genet 133:57-63. 2005..Identification of these polymorphisms may aid future candidate gene studies in disorders with altered dopamine signaling, such as schizophrenia Parkinson's disease and ADHD...
A pilot study of the effects of atomoxetine on driving performance in adults with ADHDRussell A Barkley
Medical University of South Carolina, SC, USA
J Atten Disord 10:306-16. 2007..This pilot study examines the value of a new nonstimulant (atomoxetine) for improving the driving performance of adults with ADHD...
Effects of two doses of alcohol on simulator driving performance in adults with attention-deficit/hyperactivity disorderRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Mount Pleasant, SC 29466, USA
Neuropsychology 20:77-87. 2006..The present results demonstrated that alcohol may have a greater detrimental effect on some aspects of driving performance in ADHD than control adults...
Driving performance in patients with cancer in the head and neck region: a pilot studyHon K Yuen
Occupational Therapy Educational Program, College of Health Professions, Medical University of South Carolina, 77 President Street, Charleston, SC 29425, USA
Arch Otolaryngol Head Neck Surg 133:904-9. 2007..To investigate actual driving performance in a group of patients with cancer in the head and neck region...
Symptoms versus impairment: the case for respecting DSM-IV's Criterion DMichael Gordon
Upstate Medical University, Department of Psychiatry, Syracuse, NY 13210, USA
J Atten Disord 9:465-75. 2006....
Association of the dopamine beta hydroxylase gene with attention deficit hyperactivity disorder: genetic analysis of the Milwaukee longitudinal studyKAREN MULLER SMITH
Genetics Program, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts, USA
Am J Med Genet B Neuropsychiatr Genet 119:77-85. 2003..These results indicate that the DBH TaqI A allele, or another polymorphism in linkage disequilibrium with this allele, may confer increased susceptibility towards ADHD...
Driving in young adults with attention deficit hyperactivity disorder: knowledge, performance, adverse outcomes, and the role of executive functioningRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
J Int Neuropsychol Soc 8:655-72. 2002..Findings to date argue for the development of interventions to reduce driving risks among adults with ADHD...
Young adults with attention deficit hyperactivity disorder: subtype differences in comorbidity, educational, and clinical historyKevin R Murphy
Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
J Nerv Ment Dis 190:147-57. 2002....
Psychosocial treatments for attention-deficit/hyperactivity disorder in childrenRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical School, Worcester, 55 Lake Ave N, Worcester, MA 01655, USA
J Clin Psychiatry 63:36-43. 2002..To be effective in improving prognosis, treatments must be maintained over extended periods of time...
Major life activity and health outcomes associated with attention-deficit/hyperactivity disorderRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical School, 55 Lake Ave N, Worcester, MA 01655, USA
J Clin Psychiatry 63:10-5. 2002..In the future, ADHD researchers should study outcomes for girls and women and for people with ADHD, predominately inattentive type...
Young adult outcome of hyperactive children: adaptive functioning in major life activitiesRussell A Barkley
Medical University of South Carolina, Charleston, SC, USA
J Am Acad Child Adolesc Psychiatry 45:192-202. 2006..The authors report the adaptive functioning of hyperactive and control children in southeastern Wisconsin (Milwaukee) followed to young adulthood...
Differential diagnosis of adults with ADHD: the role of executive function and self-regulationRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Charleston, SC, USA
J Clin Psychiatry 71:e17. 2010..Understanding the ways in which deficits in executive function contribute to the symptoms of ADHD can help in differentiating ADHD from disorders that share similar characteristics...
Effects of two doses of methylphenidate on simulator driving performance in adults with attention deficit hyperactivity disorderRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Charleston, SC, USA
J Safety Res 36:121-31. 2005..Numerous studies have documented an increased frequency of vehicular crashes, traffic citations, driving performance deficits, and driving-related cognitive impairments in teens and adults with attention deficit hyperactivity disorder...
Unrecognized attention-deficit/hyperactivity disorder in adults presenting with other psychiatric disordersRussell A Barkley
Medical University of South Carolina, Charleston, SC, USA
CNS Spectr 13:977-84. 2008..Therefore, management of ADHD may help to stabilize daily functioning and facilitate a fuller recovery...
An examination of the behavioral and neuropsychological correlates of three ADHD candidate gene polymorphisms (DRD4 7+, DBH TaqI A2, and DAT1 40 bp VNTR) in hyperactive and normal children followed to adulthoodRussell A Barkley
Department of Psychiatry, SUNY Upstate Medical University, Syracuse, New York, USA
Am J Med Genet B Neuropsychiatr Genet 141:487-98. 2006..We also present a contrary view on the appropriate endophenotypes for use in behavioral genetic research on ADHD...
Impairment in occupational functioning and adult ADHD: the predictive utility of executive function (EF) ratings versus EF testsRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Mt Pleasant, SC 29466, USA
Arch Clin Neuropsychol 25:157-73. 2010..Ratings of EF in daily life contribute more to such impairments than do EF tests, perhaps because, as we hypothesize, each assesses a different level in the hierarchical organization of EF as a meta-construct...
Preschool children with disruptive behavior: three-year outcome as a function of adaptive disabilityRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical Center, Worcester 01655, USA
Dev Psychopathol 14:45-67. 2002..with exposure to kindergarten moderating these adverse effects...
Adolescents with attention-deficit/hyperactivity disorder: an overview of empirically based treatmentsRussell A Barkley
Department of Psychiatry, Medical University of South Carolina, Charleston 29425, USA
J Psychiatr Pract 10:39-56. 2004..The author then discusses the use of combined treatment with psychosocial interventions and medication. Finally, information on the use of physical exercise as therapy for adolescents with ADHD is discussed...
Global issues related to the impact of untreated attention-deficit/hyperactivity disorder from childhood to young adulthoodRussell A Barkley
Department of Psychiatry, SUNY Upstate Medical School, Syracuse, NY 13210, USA
Postgrad Med 120:48-59. 2008....
Correlates of comorbid psychopathology in children with ADHDDaniel F Connor
Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
J Am Acad Child Adolesc Psychiatry 42:193-200. 2003..CONCLUSIONS: Comorbid externalizing and internalizing symptoms are correlated with age of ADHD onset and are related to the severity of clinical presentation in a referred sample of children with ADHD...
Challenges in diagnosing adults with ADHDRussell A Barkley
Department of Psychiatry, State University of New York Upstate Medical University, Syracuse, USA
J Clin Psychiatry 69:e36. 2008..Appropriate diagnostic criteria for adults may be added to the DSM-V, but, until that time, clinicians should use modifications to the current criteria...
The unique contribution of emotional impulsiveness to impairment in major life activities in hyperactive children as adultsRussell A Barkley
Medical University of South Carolina, Charleston, USA
J Am Acad Child Adolesc Psychiatry 49:503-13. 2010..Emotional impulsiveness (EI) may be a central feature of attention-deficit/hyperactivity disorder (ADHD) contributing impairment beyond the two ADHD dimensions of inattention and hyperactivity-impulsivity...
International consensus statement on ADHD. January 2002Russell A Barkley
Department of Psychiatry and Neurology, University of Massachusetts Medical School, Worcester 01655, USA
Clin Child Fam Psychol Rev 5:89-111. 2002
The persistence of attention-deficit/hyperactivity disorder into young adulthood as a function of reporting source and definition of disorderRussell A Barkley
Department of Psychiatry, University of Massachusetts Medical School, Worcester 01655, USA
J Abnorm Psychol 111:279-89. 2002..The authors conclude that previous follow-up studies that relied on self-reports might have substantially underestimated the persistence of ADHD into adulthood...
Driving anger and driving behavior in adults with ADHDTracy L Richards
Department of Psychology, Colorado State University, Fort Collins, CO 80523 1976, USA
J Atten Disord 10:54-64. 2006..This study assesses whether anger in the context of driving is associated with the negative driving outcomes experienced by individuals with ADHD...
Hyperactive children as young adults: driving abilities, safe driving behavior, and adverse driving outcomesMariellen Fischer
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI, USA
Accid Anal Prev 39:94-105. 2007..Deficits in simulator performance and safe driving behavior, however, are consistent with clinic-referred adults with ADHD suggesting ongoing risks for such adverse driving outcomes in children growing up with ADHD...
A review of driving risks and impairments associated with attention-deficit/hyperactivity disorder and the effects of stimulant medication on driving performanceRussell A Barkley
SUNY Upstate Medical School, Syracuse, NY, USA
J Safety Res 38:113-28. 2007..Effective treatment may minimize the risk in those with ADHD...
Adaptive changes related to medication treatment of ADHD: listening to parents of children in clinical trials of a novel nonstimulant medicationKeith E Saylor
Neuroscience, Inc, Old Georgetown Road Manor House, 5612 Spruce Tree Ave, 3rd Floor, Bethesda, MD 20814, USA
J Clin Psychiatry 63:23-8. 2002..Research protocols that omit parental interviews that assess adaptive and executive function may well overlook several meaningful and consequential medication-related improvements...
Executive functioning in hyperactive children as young adults: attention, inhibition, response perseveration, and the impact of comorbidityMariellen Fischer
Department of Neurology, Medical College of Wisconsin, Milwaukee, USA
Dev Neuropsychol 27:107-33. 2005..Response perseveration, however, was limited to those hyperactive children with CD by follow-up, consistent with Quay's theory of these two disorders...
Young adult follow-up of hyperactive children: self-reported psychiatric disorders, comorbidity, and the role of childhood conduct problems and teen CDMariellen Fischer
Department of Neurology, Medical College of Wisconsin, Milwaukee, USA
J Abnorm Child Psychol 30:463-75. 2002....
Childhood stimulant treatment and risk for later substance abuseMariellen Fischer
Department of Neuropsychology, Medical College of Wisconsin, Milwaukee 53226, USA
J Clin Psychiatry 64:19-23. 2003..A possible explanation for contradictory findings previously published was suggested by the existence of a number of potentially confounding variables, particularly conduct disorders, for which prior studies have failed to control...
Accuracy of self-evaluation in adults with ADHD: evidence from a driving studyLaura E Knouse
Department of Psychology, University of North Carolina at Greensboro, Greensboro, NC 27402 6170, USA
J Atten Disord 8:221-34. 2005..These findings extend research in children with ADHD to an adult sample in an important domain of functioning and may relate to findings of executive deficits associated with ADHD...
Talking to families about ADHDSam Goldstein
J Am Acad Child Adolesc Psychiatry 43:648-9. 2004
International Consensus Statement on ADHDRussell A Barkley
J Am Acad Child Adolesc Psychiatry 41:1389. 2002
Comparison of the DSM-IV combined and inattentive types of ADHD in a school-based sample of Latino/Hispanic childrenJose J Bauermeister
Department of Psychology, University Center for Psychological Services and Research, University of Puerto Rico, Rio Piedras Campus, San Juan, PR
J Child Psychol Psychiatry 46:166-79. 2005..The aim of this investigation was to examine the construct validity and distinctiveness of the inattentive type (IT) and combined type (CT) of Attention-Deficit/Hyperactivity Disorder (ADHD) in a Latino/Hispanic sample...
Diagnostic controversies in adult attention deficit hyperactivity disorderJames J McGough
Department of Psychiastry and Biobehavioral Sciences, University of California Los Angeles, Suite 1414, 300 UCLA Medical Plaza, Los Angeles, CA 90095, USA
Am J Psychiatry 161:1948-56. 2004..In this article the authors describe and contrast competing approaches for diagnosis of adult ADHD used in clinical and research practice...
Time estimation and performance on reproduction tasks in subtypes of children with attention deficit hyperactivity disorderJose J Bauermeister
University of Puerto Rico, San Juan
J Clin Child Adolesc Psychol 34:151-62. 2005..Findings suggest that ADHD is associated with a specific impairment in the capacity to reproduce rather than estimate time durations and that this may be related to the children's deficits in inhibition and working memory...
Distinguishing ADHD from juvenile bipolar disorder: a guide for primary care PAsKara Compton
Women's Clinic in West Reading, PA, USA
JAAPA 19:41-2, 44, 46-8. 2006
The prevalence and effects of adult attention deficit/hyperactivity disorder on work performance in a nationally representative sample of workersRonald C Kessler
Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
J Occup Environ Med 47:565-72. 2005..The prevalence and workplace consequences of adult attention deficit/hyperactivity disorder (ADHD) are unknown...
Clinical utility of EEG in attention deficit hyperactivity disorderSandra K Loo
UCLA Neuropsychiatric Institute, Los Angeles, California 90024, USA
Appl Neuropsychol 12:64-76. 2005....
The relevance of the still lectures to attention-deficit/hyperactivity disorder: a commentaryRussell A Barkley
SUNY Upstate Medical School
J Atten Disord 10:137-40. 2006
Research Grants
- ADULT OUTCOME OF ADHD CHILDREN--MENTAL & MEDICAL HEALTHRussell Barkley; Fiscal Year: 2001..Afterwards, all subjects will continue to be tracked as to their own marital and parental status for participation in our second project. ..
- ADULT OUTCOME OF ADHD CHILDREN: SOC/PARENTING COMPETENCERussell Barkley; Fiscal Year: 1993..Afterwards, all subjects will continue to be tracked as to their own marital and parental status for participation in our second project...
- MULTIMETHOD ASSESSMENT OF DRIVING SKILLS IN ADHD TEENSRussell Barkley; Fiscal Year: 2002..Results will have substantial clinical import concerning possible effective treatments for driving risks in ADHD youth and the adverse impact of alcohol consumption on driving in ADHD young adults. ..
