Research Topics
Species | R AlemzadehSummaryAffiliation: Medical College of Wisconsin Country: USA Publications
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Detail Information
Publications
Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty ratsRamin Alemzadeh
Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Med Sci Monit 11:BR439-48. 2005..Since the opposing effects of insulin and leptin regulate hepatic lipogenesis, we studied effects of insulin suppression on key insulin-sensitive genes regulating hepatic lipogenesis...- New adolescent polycystic ovary syndrome perspectivesR Alemzadeh
Department of Pediatrics, Section of Endocrinology and Diabetes, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Minerva Pediatr 63:35-47. 2011.... - Continuous subcutaneous insulin infusion and multiple dose of insulin regimen display similar patterns of blood glucose excursions in pediatric type 1 diabetesRamin Alemzadeh
Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
Diabetes Technol Ther 7:587-96. 2005.... - Predictors of metabolic control at one year in a population of pediatric patients with type 2 diabetes mellitus: a retrospective studyRamin Alemzadeh
Department of Pediatrics, Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
J Pediatr Endocrinol Metab 19:1141-9. 2006..This study evaluated factors that may impact glycemic control (HbA1c): age, Tanner stage, body mass index (BMI), total daily insulin (TDD), metformin dose (MET), activity level, frequency of clinic visits and adherence... - Flexible insulin therapy with glargine insulin improved glycemic control and reduced severe hypoglycemia among preschool-aged children with type 1 diabetes mellitusRamin Alemzadeh
Department of Pediatrics, Medical College of Wisconsin, Children s Research Institute, Milwaukee, Wisconsin, USA
Pediatrics 115:1320-4. 2005.... - Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxideRamin Alemzadeh
Department of Pediatrics, Section of Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Endocrinology 145:5476-84. 2004..This therapeutic strategy may be beneficial in preventing beta-cell failure and progression to diabetes in humans... - Variable effects of beta-carotene therapy in a child with erythropoietic protoporphyriaRamin Alemzadeh
Department of Pediatrics, University of Tennessee Medical Center, Knoxville, Tennessee, USA
Eur J Pediatr 163:547-9. 2004..CONCLUSION: High-dose beta-carotene appears to provide photoprotection in erythropoietic protoporphyria, resulting in improved but highly variable tolerance to sunlight... - Beneficial effects of continuous subcutaneous insulin infusion and flexible multiple daily insulin regimen using insulin glargine in type 1 diabetesRamin Alemzadeh
Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Pediatrics 114:e91-5. 2004.... - Continuous subcutaneous insulin infusion attenuated glycemic instability in preschool children with type 1 diabetes mellitusRamin Alemzadeh
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Diabetes Technol Ther 9:339-47. 2007..To evaluate indices of glycemic control and impact on quality of life, we studied a group of preschool children with type 1 diabetes mellitus (DM) on CSII... - Diazoxide enhances adipose tissue protein kinase B activation and glucose transporter-4 expression in obese Zucker ratsRamin Alemzadeh
Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Med Sci Monit 10:BR53-60. 2004.... 
Hypovitaminosis D in obese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and seasonRamin Alemzadeh
Section of Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin, WI 53226, USA
Metabolism 57:183-91. 2008..Additional studies are needed to evaluate the underlying mechanisms...- Glucose sensor evaluation of glycemic instability in pediatric type 1 diabetes mellitusRamin Alemzadeh
Department of Pediatrics, MACC Fund Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Diabetes Technol Ther 5:167-73. 2003..21, p < 0.008), independent of age, MBG, and glycemic control. The 48-h CGMS profile can help characterize day-to-day and within-day BG variability and identify factors influencing glycemic instability in pediatric type 1 DM... - Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker ratsRamin Alemzadeh
Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville, USA
Eur J Endocrinol 146:871-9. 2002..Since the liver plays a central role in glucose homeostasis, we studied the effect of chronic insulin suppression on key insulin-sensitive enzymes regulating hepatic gluconeogenesis... - Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker ratsRamin Alemzadeh
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Metabolism 57:1597-607. 2008.... - Feasibility of continuous subcutaneous insulin infusion and daily supplemental insulin glargine injection in children with type 1 diabetesRamin Alemzadeh
Children s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Diabetes Technol Ther 11:481-6. 2009.... - Spectrum of metabolic dysfunction in relationship with hyperandrogenemia in obese adolescent girls with polycystic ovary syndromeRamin Alemzadeh
Section of Pediatric Endocrinology and Metabolism, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
Eur J Endocrinol 162:1093-9. 2010..We evaluated the spectrum of metabolic dysfunction in relationship with hyperandrogenemia (HA) in adolescent girls with PCOS... - Beneficial effect of diazoxide in obese hyperinsulinemic adultsR Alemzadeh
Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville 37920, USA
J Clin Endocrinol Metab 83:1911-5. 1998..CONCLUSION: 8 weeks treatment with DZ had a significant antiobesity effect in hyperinsulinemic obese adults without inducing hyperglycemia... - Beneficial effects of metformin in normoglycemic morbidly obese adolescentsJ P Kay
Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville, TN, USA
Metabolism 50:1457-61. 2001..05) only in the metformin-treated subjects. Combined metformin treatment and low-calorie diet had a significant antiobesity effect in hyperinsulinemic obese adolescents compared to a low-calorie diet alone... - Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker ratsRamin Alemzadeh
Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
Metabolism 53:441-7. 2004..These results suggest that pharmacologic attenuation of hyperinsulinemic state by low-dose NN414 may be therapeutically beneficial in insulin-resistant states without any deterioration in overall glycemic control... - Effect of diazoxide on brain capillary insulin receptor binding and food intake in hyperphagic obese Zucker ratsR Alemzadeh
Department of Pediatrics, University of Tennessee Medical Center, Knoxville 37920, USA
Endocrinology 140:3197-202. 1999.... - Beneficial effects of flexible insulin therapy in children and adolescents with type 1 diabetes mellitusR Alemzadeh
Children's Hospital of Wisconsin, Milwaukee, WI, USA
Acta Diabetol 40:137-42. 2003..It may effectively decrease the HbA(1c), and reduce hypoglycemic episodes, without producing an abnormal increase in BMI... - Diazoxide effects on hypothalamic and extra-hypothalamic NPY content in Zucker ratsI E Hensley
Department of Psychology, University of Tennessee, Knoxville, Tennessee 37920, USA
Peptides 22:899-908. 2001..Contrary to the hypothesis, DZ increased NPY in hypothalamic nuclei of free fed lean and obese rats. DZ elevated hypothalamic NPY levels in fasted obese rats and had more diverse effects in extra-hypothalamic nuclei of lean rats... - Factors associated with adherence to continuous subcutaneous insulin infusion in pediatric diabetesGhufran S Babar
Children s Hospital of Wisconsin Diabetes Center and Sections of Pediatric Endocrinology and Metabolism and Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
Diabetes Technol Ther 11:131-7. 2009..We reviewed the clinical data from our patients to assess the predictors associated with nonadherence to CSII therapy... 
Increasing incidence of pediatric type 1 diabetes mellitus in Southeastern Wisconsin: relationship with body weight at diagnosisJennifer Evertsen
Department of Epidemiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
PLoS ONE 4:e6873. 2009..Our objective was to assess whether changing incidence of type 1 diabetes in a group of children and adolescent from the Midwest United States was associated with changes in BMI...- Attributions of adolescents with type 1 diabetes in social situations: relationship with expected adherence, diabetes stress, and metabolic controlAnthony A Hains
Department of Educational Psychology, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
Diabetes Care 29:818-22. 2006..To examine the relationships among negative attributions of friend reactions (NAFRs) within a social context, anticipated adherence difficulties, diabetes stress, and metabolic control... - Attributions of teacher reactions to diabetes self-care behaviorsAnthony A Hains
Department of Educational Psychology, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
J Pediatr Psychol 34:97-107. 2009.... - Genetic association of HLA DQB1 with CD4+CD25+(high) T-cell apoptosis in type 1 diabetesS Glisic
Department of Pediatrics, Max McGee National Center for Juvenile Diabetes and Human Molecular Genetic Center, Medical College of Wisconsin, Children s Hospital of Wisconsin, Milwaukee, WI 53226, USA
Genes Immun 10:334-40. 2009..Our study shows an association of HLA DQB1 genotypes with CD4+CD25+(high) T-cell apoptosis, which implicates CD4+CD25+(high) T-cell apoptosis as a new intermediate trait for T1D... - Impaired endothelial function in preadolescent children with type 1 diabetesGhufran S Babar
Department of Pediatric Endocrinology, Children s Mercy Hospital, Kansas City, Missouri, USA
Diabetes Care 34:681-5. 2011.... - Teacher support of adherence for adolescents with type 1 diabetes: preferred teacher support behaviors and youths' perceptions of supportAmy F Sato
Department of Psychology, University of Wisconsin Milwaukee, Milwaukee, WI, USA
Diabetes Educ 34:866-73. 2008.... - Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivationParthav Jailwala
The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin and the Children s Research Institute of the Children s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
PLoS ONE 4:e6527. 2009..Our objective here was to elucidate the genes and signaling pathways triggering apoptosis in T(regs) from T1D subjects... - Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomicsXujing Wang
Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College of Wisconsin, Children s Hospital of Wisconsin, Milwaukee 53226, USA
J Immunol 180:1929-37. 2008..Furthermore, proinflammatory serum markers may be used as inclusion criteria or endpoint measures in clinical trials aimed at preventing T1DM... 
At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fractionSanja Glisic Milosavljevic
The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children s Research Institute of the Children s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
PLoS ONE 2:e146. 2007..Recent studies have found a suppression defect of CD4+CD25+(high) T cells in human disease. In this study we measure apoptosis of CD4+CD25+(high) T cells to see if it could contribute to reduced suppressive activity of these cells...- Attributions of adolescents with type 1 diabetes related to performing diabetes care around friends and peers: the moderating role of friend supportAnthony A Hains
Department of Educational Psychology, PO Box 413, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
J Pediatr Psychol 32:561-70. 2007..To examine the relationships among negative attributions of friend and peer reactions to diabetes management in social situations, anticipated adherence difficulties, friend support, diabetes stress, and metabolic control... - Brief report: disordered eating and psychosocial factors in adolescent females with type 1 diabetes mellitusMarissa R Battaglia
Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
J Pediatr Psychol 31:552-6. 2006....