R Alemzadeh

Summary

Affiliation: Medical College of Wisconsin
Country: USA

Publications

  1. ncbi request reprint Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats
    Ramin Alemzadeh
    Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Med Sci Monit 11:BR439-48. 2005
  2. ncbi request reprint New adolescent polycystic ovary syndrome perspectives
    R Alemzadeh
    Department of Pediatrics, Section of Endocrinology and Diabetes, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Minerva Pediatr 63:35-47. 2011
  3. ncbi request reprint Continuous subcutaneous insulin infusion and multiple dose of insulin regimen display similar patterns of blood glucose excursions in pediatric type 1 diabetes
    Ramin Alemzadeh
    Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Diabetes Technol Ther 7:587-96. 2005
  4. ncbi request reprint Predictors of metabolic control at one year in a population of pediatric patients with type 2 diabetes mellitus: a retrospective study
    Ramin Alemzadeh
    Department of Pediatrics, Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Pediatr Endocrinol Metab 19:1141-9. 2006
  5. ncbi request reprint Flexible insulin therapy with glargine insulin improved glycemic control and reduced severe hypoglycemia among preschool-aged children with type 1 diabetes mellitus
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Children s Research Institute, Milwaukee, Wisconsin, USA
    Pediatrics 115:1320-4. 2005
  6. ncbi request reprint Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide
    Ramin Alemzadeh
    Department of Pediatrics, Section of Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Endocrinology 145:5476-84. 2004
  7. ncbi request reprint Variable effects of beta-carotene therapy in a child with erythropoietic protoporphyria
    Ramin Alemzadeh
    Department of Pediatrics, University of Tennessee Medical Center, Knoxville, Tennessee, USA
    Eur J Pediatr 163:547-9. 2004
  8. ncbi request reprint Beneficial effects of continuous subcutaneous insulin infusion and flexible multiple daily insulin regimen using insulin glargine in type 1 diabetes
    Ramin Alemzadeh
    Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Pediatrics 114:e91-5. 2004
  9. ncbi request reprint Continuous subcutaneous insulin infusion attenuated glycemic instability in preschool children with type 1 diabetes mellitus
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Diabetes Technol Ther 9:339-47. 2007
  10. ncbi request reprint Diazoxide enhances adipose tissue protein kinase B activation and glucose transporter-4 expression in obese Zucker rats
    Ramin Alemzadeh
    Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Med Sci Monit 10:BR53-60. 2004

Collaborators

Detail Information

Publications34

  1. ncbi request reprint Diazoxide attenuates insulin secretion and hepatic lipogenesis in zucker diabetic fatty rats
    Ramin Alemzadeh
    Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Med Sci Monit 11:BR439-48. 2005
    ..Since the opposing effects of insulin and leptin regulate hepatic lipogenesis, we studied effects of insulin suppression on key insulin-sensitive genes regulating hepatic lipogenesis...
  2. ncbi request reprint New adolescent polycystic ovary syndrome perspectives
    R Alemzadeh
    Department of Pediatrics, Section of Endocrinology and Diabetes, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Minerva Pediatr 63:35-47. 2011
    ....
  3. ncbi request reprint Continuous subcutaneous insulin infusion and multiple dose of insulin regimen display similar patterns of blood glucose excursions in pediatric type 1 diabetes
    Ramin Alemzadeh
    Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    Diabetes Technol Ther 7:587-96. 2005
    ....
  4. ncbi request reprint Predictors of metabolic control at one year in a population of pediatric patients with type 2 diabetes mellitus: a retrospective study
    Ramin Alemzadeh
    Department of Pediatrics, Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA
    J Pediatr Endocrinol Metab 19:1141-9. 2006
    ..This study evaluated factors that may impact glycemic control (HbA1c): age, Tanner stage, body mass index (BMI), total daily insulin (TDD), metformin dose (MET), activity level, frequency of clinic visits and adherence...
  5. ncbi request reprint Flexible insulin therapy with glargine insulin improved glycemic control and reduced severe hypoglycemia among preschool-aged children with type 1 diabetes mellitus
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Children s Research Institute, Milwaukee, Wisconsin, USA
    Pediatrics 115:1320-4. 2005
    ....
  6. ncbi request reprint Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide
    Ramin Alemzadeh
    Department of Pediatrics, Section of Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Endocrinology 145:5476-84. 2004
    ..This therapeutic strategy may be beneficial in preventing beta-cell failure and progression to diabetes in humans...
  7. ncbi request reprint Variable effects of beta-carotene therapy in a child with erythropoietic protoporphyria
    Ramin Alemzadeh
    Department of Pediatrics, University of Tennessee Medical Center, Knoxville, Tennessee, USA
    Eur J Pediatr 163:547-9. 2004
    ....
  8. ncbi request reprint Beneficial effects of continuous subcutaneous insulin infusion and flexible multiple daily insulin regimen using insulin glargine in type 1 diabetes
    Ramin Alemzadeh
    Children s Hospital of Wisconsin Diabetes Center, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Pediatrics 114:e91-5. 2004
    ....
  9. ncbi request reprint Continuous subcutaneous insulin infusion attenuated glycemic instability in preschool children with type 1 diabetes mellitus
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Diabetes Technol Ther 9:339-47. 2007
    ..To evaluate indices of glycemic control and impact on quality of life, we studied a group of preschool children with type 1 diabetes mellitus (DM) on CSII...
  10. ncbi request reprint Diazoxide enhances adipose tissue protein kinase B activation and glucose transporter-4 expression in obese Zucker rats
    Ramin Alemzadeh
    Section of Pediatric Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Med Sci Monit 10:BR53-60. 2004
    ....
  11. doi request reprint Hypovitaminosis D in obese children and adolescents: relationship with adiposity, insulin sensitivity, ethnicity, and season
    Ramin Alemzadeh
    Section of Endocrinology and Metabolism, Medical College of Wisconsin, Milwaukee, Wisconsin, WI 53226, USA
    Metabolism 57:183-91. 2008
    ..Additional studies are needed to evaluate the underlying mechanisms...
  12. ncbi request reprint Glucose sensor evaluation of glycemic instability in pediatric type 1 diabetes mellitus
    Ramin Alemzadeh
    Department of Pediatrics, MACC Fund Research Center, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Diabetes Technol Ther 5:167-73. 2003
    ..21, p < 0.008), independent of age, MBG, and glycemic control. The 48-h CGMS profile can help characterize day-to-day and within-day BG variability and identify factors influencing glycemic instability in pediatric type 1 DM...
  13. ncbi request reprint Chronic suppression of insulin by diazoxide alters the activities of key enzymes regulating hepatic gluconeogenesis in Zucker rats
    Ramin Alemzadeh
    Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville, USA
    Eur J Endocrinol 146:871-9. 2002
    ..Since the liver plays a central role in glucose homeostasis, we studied the effect of chronic insulin suppression on key insulin-sensitive enzymes regulating hepatic gluconeogenesis...
  14. doi request reprint Diazoxide enhances basal metabolic rate and fat oxidation in obese Zucker rats
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Metabolism 57:1597-607. 2008
    ....
  15. doi request reprint Feasibility of continuous subcutaneous insulin infusion and daily supplemental insulin glargine injection in children with type 1 diabetes
    Ramin Alemzadeh
    Children s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Diabetes Technol Ther 11:481-6. 2009
    ....
  16. doi request reprint Spectrum of metabolic dysfunction in relationship with hyperandrogenemia in obese adolescent girls with polycystic ovary syndrome
    Ramin Alemzadeh
    Section of Pediatric Endocrinology and Metabolism, Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Eur J Endocrinol 162:1093-9. 2010
    ..We evaluated the spectrum of metabolic dysfunction in relationship with hyperandrogenemia (HA) in adolescent girls with PCOS...
  17. ncbi request reprint Beneficial effect of diazoxide in obese hyperinsulinemic adults
    R Alemzadeh
    Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville 37920, USA
    J Clin Endocrinol Metab 83:1911-5. 1998
    ..v. glucose tolerance test (Bergman's minimal model) and no significant difference in glycohemoglobin values...
  18. ncbi request reprint Beneficial effects of metformin in normoglycemic morbidly obese adolescents
    J P Kay
    Department of Pediatrics, University of Tennessee, Graduate School of Medicine, Knoxville, TN, USA
    Metabolism 50:1457-61. 2001
    ..05) only in the metformin-treated subjects. Combined metformin treatment and low-calorie diet had a significant antiobesity effect in hyperinsulinemic obese adolescents compared to a low-calorie diet alone...
  19. ncbi request reprint Attenuation of hyperinsulinemia by NN414, a SUR1/Kir6.2 selective K-adenosine triphosphate channel opener, improves glucose tolerance and lipid profile in obese Zucker rats
    Ramin Alemzadeh
    Department of Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA
    Metabolism 53:441-7. 2004
    ..These results suggest that pharmacologic attenuation of hyperinsulinemic state by low-dose NN414 may be therapeutically beneficial in insulin-resistant states without any deterioration in overall glycemic control...
  20. ncbi request reprint Effect of diazoxide on brain capillary insulin receptor binding and food intake in hyperphagic obese Zucker rats
    R Alemzadeh
    Department of Pediatrics, University of Tennessee Medical Center, Knoxville 37920, USA
    Endocrinology 140:3197-202. 1999
    ....
  21. ncbi request reprint Beneficial effects of flexible insulin therapy in children and adolescents with type 1 diabetes mellitus
    R Alemzadeh
    Children s Hospital of Wisconsin, Milwaukee, WI, USA
    Acta Diabetol 40:137-42. 2003
    ..It may effectively decrease the HbA(1c), and reduce hypoglycemic episodes, without producing an abnormal increase in BMI...
  22. ncbi request reprint Diazoxide effects on hypothalamic and extra-hypothalamic NPY content in Zucker rats
    I E Hensley
    Department of Psychology, University of Tennessee, Knoxville, Tennessee 37920, USA
    Peptides 22:899-908. 2001
    ..Contrary to the hypothesis, DZ increased NPY in hypothalamic nuclei of free fed lean and obese rats. DZ elevated hypothalamic NPY levels in fasted obese rats and had more diverse effects in extra-hypothalamic nuclei of lean rats...
  23. doi request reprint Factors associated with adherence to continuous subcutaneous insulin infusion in pediatric diabetes
    Ghufran S Babar
    Children s Hospital of Wisconsin Diabetes Center and Sections of Pediatric Endocrinology and Metabolism and Biostatistics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Diabetes Technol Ther 11:131-7. 2009
    ..We reviewed the clinical data from our patients to assess the predictors associated with nonadherence to CSII therapy...
  24. pmc Increasing incidence of pediatric type 1 diabetes mellitus in Southeastern Wisconsin: relationship with body weight at diagnosis
    Jennifer Evertsen
    Department of Epidemiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
    PLoS ONE 4:e6873. 2009
    ..Our objective was to assess whether changing incidence of type 1 diabetes in a group of children and adolescent from the Midwest United States was associated with changes in BMI...
  25. ncbi request reprint Attributions of adolescents with type 1 diabetes in social situations: relationship with expected adherence, diabetes stress, and metabolic control
    Anthony A Hains
    Department of Educational Psychology, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
    Diabetes Care 29:818-22. 2006
    ..To examine the relationships among negative attributions of friend reactions (NAFRs) within a social context, anticipated adherence difficulties, diabetes stress, and metabolic control...
  26. doi request reprint Attributions of teacher reactions to diabetes self-care behaviors
    Anthony A Hains
    Department of Educational Psychology, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
    J Pediatr Psychol 34:97-107. 2009
    ....
  27. doi request reprint Genetic association of HLA DQB1 with CD4+CD25+(high) T-cell apoptosis in type 1 diabetes
    S Glisic
    Department of Pediatrics, Max McGee National Center for Juvenile Diabetes and Human Molecular Genetic Center, Medical College of Wisconsin, Children s Hospital of Wisconsin, Milwaukee, WI 53226, USA
    Genes Immun 10:334-40. 2009
    ..Our study shows an association of HLA DQB1 genotypes with CD4+CD25+(high) T-cell apoptosis, which implicates CD4+CD25+(high) T-cell apoptosis as a new intermediate trait for T1D...
  28. pmc Impaired endothelial function in preadolescent children with type 1 diabetes
    Ghufran S Babar
    Department of Pediatric Endocrinology, Children s Mercy Hospital, Kansas City, Missouri, USA
    Diabetes Care 34:681-5. 2011
    ....
  29. doi request reprint Teacher support of adherence for adolescents with type 1 diabetes: preferred teacher support behaviors and youths' perceptions of support
    Amy F Sato
    Department of Psychology, University of Wisconsin Milwaukee, Milwaukee, WI, USA
    Diabetes Educ 34:866-73. 2008
    ....
  30. pmc Apoptosis of CD4+ CD25(high) T cells in type 1 diabetes may be partially mediated by IL-2 deprivation
    Parthav Jailwala
    The Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics at the Medical College of Wisconsin and the Children s Research Institute of the Children s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
    PLoS ONE 4:e6527. 2009
    ..Our objective here was to elucidate the genes and signaling pathways triggering apoptosis in T(regs) from T1D subjects...
  31. ncbi request reprint Identification of a molecular signature in human type 1 diabetes mellitus using serum and functional genomics
    Xujing Wang
    Max McGee National Research Center for Juvenile Diabetes, Department of Pediatrics, Medical College of Wisconsin, Children s Hospital of Wisconsin, Milwaukee 53226, USA
    J Immunol 180:1929-37. 2008
    ..Furthermore, proinflammatory serum markers may be used as inclusion criteria or endpoint measures in clinical trials aimed at preventing T1DM...
  32. pmc At-risk and recent-onset type 1 diabetic subjects have increased apoptosis in the CD4+CD25+ T-cell fraction
    Sanja Glisic Milosavljevic
    The Max McGee National Center for Juvenile Diabetes and Human Molecular Genetics Center, Medical College of Wisconsin and the Children s Research Institute of the Children s Hospital of Wisconsin, Milwaukee, Wisconsin, United States of America
    PLoS ONE 2:e146. 2007
    ..Recent studies have found a suppression defect of CD4+CD25+(high) T cells in human disease. In this study we measure apoptosis of CD4+CD25+(high) T cells to see if it could contribute to reduced suppressive activity of these cells...
  33. ncbi request reprint Attributions of adolescents with type 1 diabetes related to performing diabetes care around friends and peers: the moderating role of friend support
    Anthony A Hains
    Department of Educational Psychology, PO Box 413, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA
    J Pediatr Psychol 32:561-70. 2007
    ..To examine the relationships among negative attributions of friend and peer reactions to diabetes management in social situations, anticipated adherence difficulties, friend support, diabetes stress, and metabolic control...
  34. ncbi request reprint Brief report: disordered eating and psychosocial factors in adolescent females with type 1 diabetes mellitus
    Marissa R Battaglia
    Rosalind Franklin University of Medicine and Science, North Chicago, Illinois 60064, USA
    J Pediatr Psychol 31:552-6. 2006
    ....