Kenneth A Kobak
Affiliation: MedAvante Inc
- Enriched rater training using Internet based technologies: a comparison to traditional rater training in a multi-site depression trialKenneth A Kobak
MedAvante Inc, 7601 Ganser Way, Madison, WI 53717, USA
J Psychiatr Res 40:192-9. 2006....
- A new approach to rater training and certification in a multicenter clinical trialKenneth A Kobak
MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, USA
J Clin Psychopharmacol 25:407-12. 2005..00 to 11.00, P = 0.033. Three raters failed all 3 attempts and were excluded from the study. Results support the efficacy of the approach in improving both conceptual knowledge and applied interviewing skill...
- PANSS rater training using Internet and videoconference: results from a pilot studyKenneth A Kobak
MedAvante, Inc, 7601 Ganser Way, Madison, WI 53719, USA
Schizophr Res 92:63-7. 2007..The use of these technologies allows for training to be more effectively delivered to diverse sites in multi-center trials, and for evaluation of raters' applied clinical skills, an area that has previously been overlooked...
- Face-to-face versus remote administration of the Montgomery-Asberg Depression Rating Scale using videoconference and telephoneKenneth A Kobak
MedAvante Research Institute, MedAvante Inc, Madison, Wisconsin 53719, USA
Depress Anxiety 25:913-9. 2008..Comparability of the administration mode allows for remote assessment of patients in both research and clinical applications...
- A comparison of face-to-face and remote assessment of inter-rater reliability on the Hamilton Depression Rating Scale via videoconferencingKenneth A Kobak
MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, United States
Psychiatry Res 158:99-103. 2008..88). The mean Hamilton Depression Rating Scale (HAMD) scores obtained were not significantly different. There appears to be no loss of signal using remote methods of calibration compared with traditional face-to-face methods...
- Sources of unreliability in depression ratingsKenneth A Kobak
MedAvante Research Institute, Madison, WI, USA
J Clin Psychopharmacol 29:82-5. 2009..We videotaped and transcribed 30 pairs of interviews to examine the most common sources of rater unreliability...
- A novel approach to rater training and certification in multinational trialsElizabeth Jeglic
MedAvante Research Institute, Ganser Way, Madison, Wisconsin 53719, USA
Int Clin Psychopharmacol 22:187-91. 2007..25 to 11.31, P=0.003. These results support the efficacy of this applied training model in improving raters' applied clinical skills in multinational trials...
- Rating the raters: assessing the quality of Hamilton rating scale for depression clinical interviews in two industry-sponsored clinical drug trialsNina Engelhardt
MedAvante, Inc MedAvante, Ewing, NJ, USA
J Clin Psychopharmacol 26:71-4. 2006..We evaluated the quality of Hamilton Rating Scale for Depression (HAM-D) clinical interviews performed at baseline in 2 similar multicenter, randomized, placebo-controlled depression trials sponsored by 2 pharmaceutical companies...
- A comparison of face-to-face and videoconference administration of the Hamilton Depression Rating ScaleKenneth A Kobak
Research Training Associates and MedAvante, Madison, Wisconsin 53719, USA
J Telemed Telecare 10:231-5. 2004..The study shows the psychometric equivalence of remote and face-to-face HAMD administration...
- Development of a standardized training program for the Hamilton Depression Scale using internet-based technologies: results from a pilot studyKenneth A Kobak
Research Training Associates, Madison, WI 53719, USA
J Psychiatr Res 37:509-15. 2003..97, P<0.0001. Results support the feasibility of this methodology for improving rater training. An NIMH funded study is currently underway examining this methodology in a multi-site trial...
- Site versus centralized raters in a clinical depression trial: impact on patient selection and placebo responseKenneth A Kobak
MedAvante, Inc, Madison, WI 53719, USA
J Clin Psychopharmacol 30:193-7. 2010..Findings suggest that the use of centralized raters could significantly change the study sample in a major depressive disorder trial and lead to significantly less change in mood ratings among those randomized to placebo...
- A web-based tutorial for parents of young children with autism: results from a pilot studyKenneth A Kobak
Center for Psychological Consultation, Madison, Wisconsin 53717, USA
Telemed J E Health 17:804-8. 2011..To bridge this gap, we evaluated a Web-based parent training tutorial (Enhancing Interactions), based on evidence-based practices and utilizing the Web-based platform to maximize learning...
- Development and reliability of a structured interview guide for the Montgomery Asberg Depression Rating Scale (SIGMA)Janet B W Williams
Biometrics Research Unit, Columbia University, New York, New York, USA
Br J Psychiatry 192:52-8. 2008..Structured and semi-structured interview guides have been found to improve reliability with other scales...
- Web-based training in early autism screening: results from a pilot studyKenneth A Kobak
Center for Psychological Consultation, Madison, Wisconsin 53717, USA
Telemed J E Health 17:640-4. 2011..This study evaluated the efficacy and acceptability of Web-based training of the STAT as a means of increasing accessibility to this training...
- St. John's wort versus placebo in social phobia: results from a placebo-controlled pilot studyKenneth A Kobak
Dean Foundation for Health Research and Education, Middleton, WI, USA
J Clin Psychopharmacol 25:51-8. 2005..Results of the study fail to provide evidence for the efficacy of SJW in social phobia. The impact of methodologic improvements on signal detection, while suggestive of improvement, remains to be established...
- Behavior therapy for obsessive-compulsive disorder guided by a computer or by a clinician compared with relaxation as a controlJohn H Greist
Healthcare Technology Systems, and the University of Wisconsin, Madison, 53717, USA
J Clin Psychiatry 63:138-45. 2002..This study compared the value of computer-guided behavior therapy value with that of clinician-guided behavior therapy and systematic relaxation as a control treatment...
- The use of videoconferencing with patients with psychosis: a review of the literatureIan R Sharp
MedAvante Research Institute, Hamilton, NJ, USA
Ann Gen Psychiatry 10:14. 2011..The results of two large clinical trials support the reliability and effectiveness of centralized remote assessment of patients with schizophrenia...
- The GRID-HAMD: standardization of the Hamilton Depression Rating ScaleJanet B W Williams
Columbia University, New York, NY, USA
Int Clin Psychopharmacol 23:120-9. 2008..Overall, these data suggest that the GRID-HAMD is an improvement over the original Guy version as well as the SIGH-D in its incorporation of innovative features and preservation of high reliability and validity...
- Why the Hamilton Depression Rating Scale enduresPer Bech
Am J Psychiatry 162:2396; author reply 2397-8. 2005
- Are the effects of rater training sustainable? Results from a multicenter clinical trialKenneth A Kobak
J Clin Psychopharmacol 27:534-5. 2007
- Interview quality and signal detection in clinical trialsKenneth A Kobak
Am J Psychiatry 162:628. 2005
- Pharmacist telemonitoring of antidepressant use: effects on pharmacist-patient collaborationNathaniel M Rickles
Department of Pharmacy Practice, School of Pharmacy, Northeastern University, 206 Mugar Life Sciences Building, Boston, MA 02115, USA
J Am Pharm Assoc (2003) 45:344-53. 2005..To explore the impact of telephone-based education and monitoring by community pharmacists on multiple outcomes of pharmacist-patient collaboration...
- Antidepressant medication management and Health Plan Employer Data Information Set (HEDIS) criteria: reasons for nonadherenceKenneth A Kobak
Dean Foundation for Health, Research and Education, 2711 Allen Blvd, Middleton, WI 53562, USA
J Clin Psychiatry 63:727-32. 2002..We examined the reasons for this failure through a systematic chart review...
- Fluoxetine in social phobia: a double-blind, placebo-controlled pilot studyKenneth A Kobak
Dean Foundation for Health, Research and Education, Middleton, Wisconsin, USA
J Clin Psychopharmacol 22:257-62. 2002..Fluoxetine failed to separate from placebo in this trial. It is unknown whether a larger dose for longer duration would have yielded separation from placebo. A higher than usual placebo response rate was found...
- Improving patient feedback about and outcomes with antidepressant treatment: a study in eight community pharmaciesNathaniel M Rickles
Department of Pharmacy Practice, School of Pharmacy, Northeastern University, 206 Mugar Life Sciences Building, Boston, MA 02446, USA
J Am Pharm Assoc (2003) 46:25-32. 2006....
- St John's wort versus placebo in obsessive-compulsive disorder: results from a double-blind studyKenneth A Kobak
Dean Foundation for Health Research and Education, Middleton, Wisconsin 53562, USA
Int Clin Psychopharmacol 20:299-304. 2005..9%) and placebo (16.7%) (P=0.905). Only one patient from each group discontinued due to adverse events [sinus infection (St John's wort); confusion (placebo)]. The results fail to support the efficacy of St John's wort for OCD...
- Rater training in multicenter clinical trials: issues and recommendationsKenneth A Kobak
J Clin Psychopharmacol 24:113-7. 2004
- St. John's Wort vs Placebo in Social PhobiaKenneth Kobak; Fiscal Year: 2002..An intent-to-treat analysis will be employed. Subjects will be evaluated weekly for two weeks, then bi-weekly thereafter. The primary outcome measure will be the change from baseline to endpoint on the Liebowitz Social Anxiety Scale. ..
- R21 Project: St. John's Wort vs. Placebo in OCDKenneth Kobak; Fiscal Year: 2003..35 hypericin) or matching placebo. This will be a fixed-dose design at 450 mg bid. An intent-to- treat analysis will be employed Subjects will be evaluated weekly for two weeks than bi-weekly thereafter. ..
- PANSS Rater Training Using Internet and VideoconferenceKenneth Kobak; Fiscal Year: 2006..Our previous studies on the use of this training paradigm (CD-ROM plus live applied training) has been shown to be successful in the areas of both depression and autism assessment. ..