Kenneth A Kobak

Summary

Affiliation: MedAvante Inc
Country: USA

Publications

  1. ncbi request reprint Enriched rater training using Internet based technologies: a comparison to traditional rater training in a multi-site depression trial
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53717, USA
    J Psychiatr Res 40:192-9. 2006
  2. ncbi request reprint A new approach to rater training and certification in a multicenter clinical trial
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, USA
    J Clin Psychopharmacol 25:407-12. 2005
  3. ncbi request reprint PANSS rater training using Internet and videoconference: results from a pilot study
    Kenneth A Kobak
    MedAvante, Inc, 7601 Ganser Way, Madison, WI 53719, USA
    Schizophr Res 92:63-7. 2007
  4. ncbi request reprint Face-to-face versus remote administration of the Montgomery-Asberg Depression Rating Scale using videoconference and telephone
    Kenneth A Kobak
    MedAvante Research Institute, MedAvante Inc, Madison, Wisconsin 53719, USA
    Depress Anxiety 25:913-9. 2008
  5. ncbi request reprint A comparison of face-to-face and remote assessment of inter-rater reliability on the Hamilton Depression Rating Scale via videoconferencing
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, United States
    Psychiatry Res 158:99-103. 2008
  6. doi request reprint Sources of unreliability in depression ratings
    Kenneth A Kobak
    MedAvante Research Institute, Madison, WI, USA
    J Clin Psychopharmacol 29:82-5. 2009
  7. ncbi request reprint A novel approach to rater training and certification in multinational trials
    Elizabeth Jeglic
    MedAvante Research Institute, Ganser Way, Madison, Wisconsin 53719, USA
    Int Clin Psychopharmacol 22:187-91. 2007
  8. ncbi request reprint Rating the raters: assessing the quality of Hamilton rating scale for depression clinical interviews in two industry-sponsored clinical drug trials
    Nina Engelhardt
    MedAvante, Inc MedAvante, Ewing, NJ, USA
    J Clin Psychopharmacol 26:71-4. 2006
  9. ncbi request reprint A comparison of face-to-face and videoconference administration of the Hamilton Depression Rating Scale
    Kenneth A Kobak
    Research Training Associates and MedAvante, Madison, Wisconsin 53719, USA
    J Telemed Telecare 10:231-5. 2004
  10. ncbi request reprint Development of a standardized training program for the Hamilton Depression Scale using internet-based technologies: results from a pilot study
    Kenneth A Kobak
    Research Training Associates, Madison, WI 53719, USA
    J Psychiatr Res 37:509-15. 2003

Research Grants

Detail Information

Publications27

  1. ncbi request reprint Enriched rater training using Internet based technologies: a comparison to traditional rater training in a multi-site depression trial
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53717, USA
    J Psychiatr Res 40:192-9. 2006
    ....
  2. ncbi request reprint A new approach to rater training and certification in a multicenter clinical trial
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, USA
    J Clin Psychopharmacol 25:407-12. 2005
    ..00 to 11.00, P = 0.033. Three raters failed all 3 attempts and were excluded from the study. Results support the efficacy of the approach in improving both conceptual knowledge and applied interviewing skill...
  3. ncbi request reprint PANSS rater training using Internet and videoconference: results from a pilot study
    Kenneth A Kobak
    MedAvante, Inc, 7601 Ganser Way, Madison, WI 53719, USA
    Schizophr Res 92:63-7. 2007
    ..The use of these technologies allows for training to be more effectively delivered to diverse sites in multi-center trials, and for evaluation of raters' applied clinical skills, an area that has previously been overlooked...
  4. ncbi request reprint Face-to-face versus remote administration of the Montgomery-Asberg Depression Rating Scale using videoconference and telephone
    Kenneth A Kobak
    MedAvante Research Institute, MedAvante Inc, Madison, Wisconsin 53719, USA
    Depress Anxiety 25:913-9. 2008
    ..Comparability of the administration mode allows for remote assessment of patients in both research and clinical applications...
  5. ncbi request reprint A comparison of face-to-face and remote assessment of inter-rater reliability on the Hamilton Depression Rating Scale via videoconferencing
    Kenneth A Kobak
    MedAvante Inc, 7601 Ganser Way, Madison, WI 53719, United States
    Psychiatry Res 158:99-103. 2008
    ..88). The mean Hamilton Depression Rating Scale (HAMD) scores obtained were not significantly different. There appears to be no loss of signal using remote methods of calibration compared with traditional face-to-face methods...
  6. doi request reprint Sources of unreliability in depression ratings
    Kenneth A Kobak
    MedAvante Research Institute, Madison, WI, USA
    J Clin Psychopharmacol 29:82-5. 2009
    ..We videotaped and transcribed 30 pairs of interviews to examine the most common sources of rater unreliability...
  7. ncbi request reprint A novel approach to rater training and certification in multinational trials
    Elizabeth Jeglic
    MedAvante Research Institute, Ganser Way, Madison, Wisconsin 53719, USA
    Int Clin Psychopharmacol 22:187-91. 2007
    ..25 to 11.31, P=0.003. These results support the efficacy of this applied training model in improving raters' applied clinical skills in multinational trials...
  8. ncbi request reprint Rating the raters: assessing the quality of Hamilton rating scale for depression clinical interviews in two industry-sponsored clinical drug trials
    Nina Engelhardt
    MedAvante, Inc MedAvante, Ewing, NJ, USA
    J Clin Psychopharmacol 26:71-4. 2006
    ..We evaluated the quality of Hamilton Rating Scale for Depression (HAM-D) clinical interviews performed at baseline in 2 similar multicenter, randomized, placebo-controlled depression trials sponsored by 2 pharmaceutical companies...
  9. ncbi request reprint A comparison of face-to-face and videoconference administration of the Hamilton Depression Rating Scale
    Kenneth A Kobak
    Research Training Associates and MedAvante, Madison, Wisconsin 53719, USA
    J Telemed Telecare 10:231-5. 2004
    ..The study shows the psychometric equivalence of remote and face-to-face HAMD administration...
  10. ncbi request reprint Development of a standardized training program for the Hamilton Depression Scale using internet-based technologies: results from a pilot study
    Kenneth A Kobak
    Research Training Associates, Madison, WI 53719, USA
    J Psychiatr Res 37:509-15. 2003
    ..97, P<0.0001. Results support the feasibility of this methodology for improving rater training. An NIMH funded study is currently underway examining this methodology in a multi-site trial...
  11. doi request reprint Site versus centralized raters in a clinical depression trial: impact on patient selection and placebo response
    Kenneth A Kobak
    MedAvante, Inc, Madison, WI 53719, USA
    J Clin Psychopharmacol 30:193-7. 2010
    ..Findings suggest that the use of centralized raters could significantly change the study sample in a major depressive disorder trial and lead to significantly less change in mood ratings among those randomized to placebo...
  12. pmc A web-based tutorial for parents of young children with autism: results from a pilot study
    Kenneth A Kobak
    Center for Psychological Consultation, Madison, Wisconsin 53717, USA
    Telemed J E Health 17:804-8. 2011
    ..To bridge this gap, we evaluated a Web-based parent training tutorial (Enhancing Interactions), based on evidence-based practices and utilizing the Web-based platform to maximize learning...
  13. doi request reprint Development and reliability of a structured interview guide for the Montgomery Asberg Depression Rating Scale (SIGMA)
    Janet B W Williams
    Biometrics Research Unit, Columbia University, New York, New York, USA
    Br J Psychiatry 192:52-8. 2008
    ..Structured and semi-structured interview guides have been found to improve reliability with other scales...
  14. pmc Web-based training in early autism screening: results from a pilot study
    Kenneth A Kobak
    Center for Psychological Consultation, Madison, Wisconsin 53717, USA
    Telemed J E Health 17:640-4. 2011
    ..This study evaluated the efficacy and acceptability of Web-based training of the STAT as a means of increasing accessibility to this training...
  15. ncbi request reprint St. John's wort versus placebo in social phobia: results from a placebo-controlled pilot study
    Kenneth A Kobak
    Dean Foundation for Health Research and Education, Middleton, WI, USA
    J Clin Psychopharmacol 25:51-8. 2005
    ..Results of the study fail to provide evidence for the efficacy of SJW in social phobia. The impact of methodologic improvements on signal detection, while suggestive of improvement, remains to be established...
  16. ncbi request reprint Behavior therapy for obsessive-compulsive disorder guided by a computer or by a clinician compared with relaxation as a control
    John H Greist
    Healthcare Technology Systems, and the University of Wisconsin, Madison, 53717, USA
    J Clin Psychiatry 63:138-45. 2002
    ..This study compared the value of computer-guided behavior therapy value with that of clinician-guided behavior therapy and systematic relaxation as a control treatment...
  17. pmc The use of videoconferencing with patients with psychosis: a review of the literature
    Ian R Sharp
    MedAvante Research Institute, Hamilton, NJ, USA
    Ann Gen Psychiatry 10:14. 2011
    ..The results of two large clinical trials support the reliability and effectiveness of centralized remote assessment of patients with schizophrenia...
  18. doi request reprint The GRID-HAMD: standardization of the Hamilton Depression Rating Scale
    Janet B W Williams
    Columbia University, New York, NY, USA
    Int Clin Psychopharmacol 23:120-9. 2008
    ..Overall, these data suggest that the GRID-HAMD is an improvement over the original Guy version as well as the SIGH-D in its incorporation of innovative features and preservation of high reliability and validity...
  19. ncbi request reprint Why the Hamilton Depression Rating Scale endures
    Per Bech
    Am J Psychiatry 162:2396; author reply 2397-8. 2005
  20. ncbi request reprint Are the effects of rater training sustainable? Results from a multicenter clinical trial
    Kenneth A Kobak
    J Clin Psychopharmacol 27:534-5. 2007
  21. ncbi request reprint Interview quality and signal detection in clinical trials
    Kenneth A Kobak
    Am J Psychiatry 162:628. 2005
  22. ncbi request reprint Pharmacist telemonitoring of antidepressant use: effects on pharmacist-patient collaboration
    Nathaniel M Rickles
    Department of Pharmacy Practice, School of Pharmacy, Northeastern University, 206 Mugar Life Sciences Building, Boston, MA 02115, USA
    J Am Pharm Assoc (2003) 45:344-53. 2005
    ..To explore the impact of telephone-based education and monitoring by community pharmacists on multiple outcomes of pharmacist-patient collaboration...
  23. ncbi request reprint Antidepressant medication management and Health Plan Employer Data Information Set (HEDIS) criteria: reasons for nonadherence
    Kenneth A Kobak
    Dean Foundation for Health, Research and Education, 2711 Allen Blvd, Middleton, WI 53562, USA
    J Clin Psychiatry 63:727-32. 2002
    ..We examined the reasons for this failure through a systematic chart review...
  24. ncbi request reprint Fluoxetine in social phobia: a double-blind, placebo-controlled pilot study
    Kenneth A Kobak
    Dean Foundation for Health, Research and Education, Middleton, Wisconsin, USA
    J Clin Psychopharmacol 22:257-62. 2002
    ..Fluoxetine failed to separate from placebo in this trial. It is unknown whether a larger dose for longer duration would have yielded separation from placebo. A higher than usual placebo response rate was found...
  25. ncbi request reprint Improving patient feedback about and outcomes with antidepressant treatment: a study in eight community pharmacies
    Nathaniel M Rickles
    Department of Pharmacy Practice, School of Pharmacy, Northeastern University, 206 Mugar Life Sciences Building, Boston, MA 02446, USA
    J Am Pharm Assoc (2003) 46:25-32. 2006
    ....
  26. ncbi request reprint St John's wort versus placebo in obsessive-compulsive disorder: results from a double-blind study
    Kenneth A Kobak
    Dean Foundation for Health Research and Education, Middleton, Wisconsin 53562, USA
    Int Clin Psychopharmacol 20:299-304. 2005
    ..9%) and placebo (16.7%) (P=0.905). Only one patient from each group discontinued due to adverse events [sinus infection (St John's wort); confusion (placebo)]. The results fail to support the efficacy of St John's wort for OCD...
  27. ncbi request reprint Rater training in multicenter clinical trials: issues and recommendations
    Kenneth A Kobak
    J Clin Psychopharmacol 24:113-7. 2004

Research Grants3

  1. St. John's Wort vs Placebo in Social Phobia
    Kenneth Kobak; Fiscal Year: 2002
    ..An intent-to-treat analysis will be employed. Subjects will be evaluated weekly for two weeks, then bi-weekly thereafter. The primary outcome measure will be the change from baseline to endpoint on the Liebowitz Social Anxiety Scale. ..
  2. R21 Project: St. John's Wort vs. Placebo in OCD
    Kenneth Kobak; Fiscal Year: 2003
    ..35 hypericin) or matching placebo. This will be a fixed-dose design at 450 mg bid. An intent-to- treat analysis will be employed Subjects will be evaluated weekly for two weeks than bi-weekly thereafter. ..
  3. PANSS Rater Training Using Internet and Videoconference
    Kenneth Kobak; Fiscal Year: 2006
    ..Our previous studies on the use of this training paradigm (CD-ROM plus live applied training) has been shown to be successful in the areas of both depression and autism assessment. ..