Jean W Lee

Summary

Affiliation: MDS Pharma Services
Country: USA

Publications

  1. ncbi request reprint Fit-for-purpose method development and validation for successful biomarker measurement
    Jean W Lee
    Formerly MDS Pharma Services, Lincoln, Nebraska, USA
    Pharm Res 23:312-28. 2006
  2. ncbi request reprint Biomarker assay translation from discovery to clinical studies in cancer drug development: quantification of emerging protein biomarkers
    Jean W Lee
    Amgen Inc, Thousand Oaks, California 91320, USA
    Adv Cancer Res 96:269-98. 2007
  3. ncbi request reprint Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: a conference report
    Jean W Lee
    MDS Pharma Services, Lincoln, Nebraska, USA
    Pharm Res 22:499-511. 2005
  4. ncbi request reprint Supercritical fluid chromatography-tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma
    Roger A Coe
    MDS Pharma Services, 621 Rose Street, Lincoln, NE 68502, USA
    J Pharm Biomed Anal 42:573-80. 2006
  5. ncbi request reprint Biomarkers, validation and pharmacokinetic-pharmacodynamic modelling
    Wayne A Colburn
    MDS Pharma Services, Phoenix, Arizona, USA
    Clin Pharmacokinet 42:997-1022. 2003
  6. ncbi request reprint Quantification of uric acid, xanthine and hypoxanthine in human serum by HPLC for pharmacodynamic studies
    Nancy Cooper
    MDS Pharma Services, Lincoln, NE 68501, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 837:1-10. 2006
  7. ncbi request reprint Quantification of recombinant human parathyroid hormone (rhPTH(1-84)) in human plasma by immunoassay: commercial kit evaluation and validation to support pharmacokinetic studies
    Richard L Sukovaty
    MDS Pharma Services, Lincoln, NE, USA
    J Pharm Biomed Anal 42:261-71. 2006
  8. ncbi request reprint A general approach for the quantitative analysis of bisphosphonates in human serum and urine by high-performance liquid chromatography/tandem mass spectrometry
    Lee S Zhu
    MDS Pharma Services, 621 Rose Street, Lincoln, NE 68502, USA
    Rapid Commun Mass Spectrom 20:3421-6. 2006

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Fit-for-purpose method development and validation for successful biomarker measurement
    Jean W Lee
    Formerly MDS Pharma Services, Lincoln, Nebraska, USA
    Pharm Res 23:312-28. 2006
    ..Sample analysis within this context of fit-for-purpose method development and validation are well suited for successful biomarker implementation, allowing increased use of biomarkers in drug development...
  2. ncbi request reprint Biomarker assay translation from discovery to clinical studies in cancer drug development: quantification of emerging protein biomarkers
    Jean W Lee
    Amgen Inc, Thousand Oaks, California 91320, USA
    Adv Cancer Res 96:269-98. 2007
    ..Specific references to protein biomarkers for cancer drug development are also discussed...
  3. ncbi request reprint Method validation and measurement of biomarkers in nonclinical and clinical samples in drug development: a conference report
    Jean W Lee
    MDS Pharma Services, Lincoln, Nebraska, USA
    Pharm Res 22:499-511. 2005
    ....
  4. ncbi request reprint Supercritical fluid chromatography-tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma
    Roger A Coe
    MDS Pharma Services, 621 Rose Street, Lincoln, NE 68502, USA
    J Pharm Biomed Anal 42:573-80. 2006
    ..0% C.V. for S-warfarin; and the bias was 3.7 and 3.2% R.E., respectively. The method is sensitive, accurate, selective and robust, and was applied to a drug-interaction clinical study with rapid turnaround of sample analysis...
  5. ncbi request reprint Biomarkers, validation and pharmacokinetic-pharmacodynamic modelling
    Wayne A Colburn
    MDS Pharma Services, Phoenix, Arizona, USA
    Clin Pharmacokinet 42:997-1022. 2003
    ....
  6. ncbi request reprint Quantification of uric acid, xanthine and hypoxanthine in human serum by HPLC for pharmacodynamic studies
    Nancy Cooper
    MDS Pharma Services, Lincoln, NE 68501, USA
    J Chromatogr B Analyt Technol Biomed Life Sci 837:1-10. 2006
    ..The method was simple and robust with good accuracy and precision for the measurement of serum UA, X, and HX concentrations...
  7. ncbi request reprint Quantification of recombinant human parathyroid hormone (rhPTH(1-84)) in human plasma by immunoassay: commercial kit evaluation and validation to support pharmacokinetic studies
    Richard L Sukovaty
    MDS Pharma Services, Lincoln, NE, USA
    J Pharm Biomed Anal 42:261-71. 2006
    ....
  8. ncbi request reprint A general approach for the quantitative analysis of bisphosphonates in human serum and urine by high-performance liquid chromatography/tandem mass spectrometry
    Lee S Zhu
    MDS Pharma Services, 621 Rose Street, Lincoln, NE 68502, USA
    Rapid Commun Mass Spectrom 20:3421-6. 2006
    ..The general applicability of the approach was demonstrated by validation of bioanalytical methods for risedronate and alendronate in human serum and urine. Sensitivity was achieved at the pg/mL level with merely 100-200 microL of sample...