Research Topics
| Lynne V McFarlandSummaryCountry: USA Publications
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Publications
Alternative treatments for Clostridium difficile disease: what really works?Lynne V McFarland
University of Washington, HSR and D, 1100 Olive Street, 1400, Seattle, WA 98101, USA
J Med Microbiol 54:101-11. 2005..This review will describe such treatments and examine the evidence for each strategy...- Implications of the changing face of Clostridium difficile disease for health care practitionersLynne V McFarland
From the Department of Health Services Research and Development, Veterans Administration Puget Sound Health Care System, Seattle, WA 98101, USA
Am J Infect Control 35:237-53. 2007.... - Breaking the cycle: treatment strategies for 163 cases of recurrent Clostridium difficile diseaseLynne V McFarland
Department of Medicinal Chemistry, School of Pharmacy, University of Washington, Seattle, USA
Am J Gastroenterol 97:1769-75. 2002..The persistence of C. difficile spores suggests that additional strategies to restore the normal colonic microflora may also be beneficial... 
Diarrhoea associated with antibiotic useLynne V McFarland
BMJ 335:54-5. 2007
Update on the changing epidemiology of Clostridium difficile-associated diseaseLynne V McFarland
Department of Health Services Research and Development, Puget Sound VA Health Care System, Seattle, WA, USA
Nat Clin Pract Gastroenterol Hepatol 5:40-8. 2008..Infection control programs and more effective treatments offer hope that future outbreaks of CDAD can be controlled...- A teledermatology care management protocol for tracking completion of teledermatology recommendationsKristin L Eastman
Health Services R and D, Metropolitan Park West, 1100 Olive Way 1400, Seattle WA 98101, USA
J Telemed Telecare 18:374-8. 2012..The follow-up was important in ensuring high quality patient care... - Implementation of an education and skills programme in a teledermatology project for rural veteransLynne V McFarland
VA Puget Sound Health Care System, Health Services Research and Development, 1100 Olive Way, Suite 1400, Seattle, WA 98101, USA
J Telemed Telecare 18:66-71. 2012..The educational component of the teledermatology project created teams of primary care health-care providers and imaging technicians with improved dermatology educational levels and new dermatology skills... - Antibiotic-associated diarrhea: epidemiology, trends and treatmentLynne V McFarland
Department of Health Services Research and Development, Puget Sound Veterans Administration, Healthcare System, Seattle, WA 98101, USA
Future Microbiol 3:563-78. 2008..The key to addressing AAD is prompt diagnosis followed by effective treatment and institution of control measures. Areas of active research include the search for other etiologies and more effective treatments... - Fluoroquinolone use and risk factors for Clostridium difficile-associated disease within a Veterans Administration health care systemLynne V McFarland
Department of Health Services Research and Development, Veterans Administration Puget Sound Health Care System, Seattle, WA 98101, USA
Clin Infect Dis 45:1141-51. 2007..difficile-associated disease was noted at our health care center (Veterans Administration Puget Sound Health Care System, Seattle, Washington)... - Meta-analysis of probiotics for the treatment of irritable bowel syndromeLynne V McFarland
Department of Health Services Research and Development, VA Puget Sound Health Care System, Seattle WA 98101, United States
World J Gastroenterol 14:2650-61. 2008..Probiotics warrant further study as a potential therapy for IBS... - Unilateral upper-limb loss: satisfaction and prosthetic-device use in veterans and servicemembers from Vietnam and OIF/OEF conflictsLynne V McFarland
Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA 98101, USA
J Rehabil Res Dev 47:299-316. 2010..A significant paradigm shift has been noted in the OIF/OEF group, who use a greater number and diversity of upper-limb prostheses than the Vietnam group... - Renewed interest in a difficult disease: Clostridium difficile infections--epidemiology and current treatment strategiesLynne V McFarland
Department of Health Services Research and Development, Puget Sound VA Healthcare System, Seattle, Washington 98101, USA
Curr Opin Gastroenterol 25:24-35. 2009..This review summarizes recent progress in the field, particularly in relation to the changing epidemiologic trends and new investigational treatments... - Evidence-based review of probiotics for antibiotic-associated diarrhea and Clostridium difficile infectionsLynne V McFarland
Department of Health Services Research and Development, Puget Sound Veterans Administration Healthcare System, Seattle, WA 98101, USA
Anaerobe 15:274-80. 2009..Overall, probiotics offer a promising strategy for the prevention and treatment for AAD and CDI... - Systematic review and meta-analysis of Saccharomyces boulardii in adult patientsLynne V McFarland
Department of Health Services Research and Development, Puget Sound Veterans Administration Healthcare System, S 152, 1100 Olive Way 1400, Seattle, WA 98101, United States
World J Gastroenterol 16:2202-22. 2010..The use of S. boulardii as a therapeutic probiotic is evidence-based for both efficacy and safety for several types of diarrhea... - Emerging therapies for Clostridium difficile infectionsLynne V McFarland
Puget Sound VA Healthcare System, Department of Health Services Research and Development, Seattle, WA 98101, USA
Expert Opin Emerg Drugs 16:425-39. 2011..Use of other clostridial strains, probiotic strains and immune enhancers have great potential as therapies, but require further development... - Prosthetic cost projections for servicemembers with major limb loss from Vietnam and OIF/OEFDavid K Blough
Department of Pharmacy, University of Washington, Seattle, WA 98195 7630, USA
J Rehabil Res Dev 47:387-402. 2010.... - Servicemembers and veterans with major traumatic limb loss from Vietnam war and OIF/OEF conflicts: survey methods, participants, and summary findingsGayle E Reiber
Health Services Research and Development Service, Department of Veterans Affairs Puget Sound Health Care System, Seattle, WA 98101, USA
J Rehabil Res Dev 47:275-97. 2010..7-fold higher for OIF/OEF than for Vietnam war survey participants. Findings from this cross-conflict survey identify many strengths in prosthetic rehabilitation for those with limb loss and several areas for future attention... - Department of Veterans Affairs compensation and medical care benefits accorded to veterans with major limb lossCharles Maynard
Health Services Research and Development, Department of Veterans Affairs VA Puget Sound Health Care System, Seattle, WA, USA
J Rehabil Res Dev 47:403-8. 2010..A special obligation exists to those who have sustained serious injuries related to combat; this responsibility extends for the life of the servicemember and beyond to his or her spouse and dependents... - Teledermatology patient satisfaction in the Pacific NorthwestMartha T Hsueh
University of Washington School of Nursing, Seattle, Washington, USA
Telemed J E Health 18:377-81. 2012..The aim of this quality improvement project is to assess patient satisfaction with a store-and-forward teledermatology project and to identify factors associated with patient satisfaction and dissatisfaction... - Meta-analysis of probiotics for the prevention of antibiotic associated diarrhea and the treatment of Clostridium difficile diseaseLynne V McFarland
Department of Health Services Research and Development, Veterans Administration Puget Sound Health Care System, Seattle, Washington 98101, USA
Am J Gastroenterol 101:812-22. 2006..Only S. boulardii was effective for CDD... - Meta-analysis of probiotics for the prevention of traveler's diarrheaLynne V McFarland
Department of Health Services Research and Development, VA Puget Sound Health Care System, S 152, Metropolitan Park West, 1100 Olive Way, Suite 1400, Seattle, WA 98101, USA
Travel Med Infect Dis 5:97-105. 2007..The use of probiotics for this disease remains controversial. The objective of this study was to compare the efficacy of probiotics for the prevention of TD based on published randomized, controlled clinical trials... - Alcohol consumption among urban, suburban, and rural Veterans Affairs outpatientsEmily C Williams
Health Services Research and Development HSR and D, Veterans Affairs VA Puget Sound Health Care System, Seattle, Washington 98101, USA
J Rural Health 28:202-10. 2012..We sought to describe alcohol consumption among urban, suburban, and rural Veterans Affairs (VA) outpatients... - Guidelines for Diagnosis, Treatment, and Prevention of Clostridium difficile InfectionsChristina M Surawicz
Division of Gastroenterology, Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA
Am J Gastroenterol 108:478-98. 2013..We propose a classification of disease severity to guide therapy that is useful for clinicians. We review current treatment options for patients with recurrent CDI and recommendations for the control and prevention of outbreaks of CDI... - Postoperative dressing and management strategies for transtibial amputations: a critical reviewDouglas G Smith
Department of Orthopedics and Sports Medicine, University of Washington, Seattle, WA 98104, USA
J Rehabil Res Dev 40:213-24. 2003..Analysis of 10 controlled studies supported only 4 of the 14 claims cited in uncontrolled, descriptive studies... - Recruitment of Medicaid and dual-enrolled Medicare beneficiaries with diabetes mellitus into a randomized controlled trialLynne V McFarland
Department of Health Services Research and Development, VA Puget Sound Health Care System, Seattle, WA 98101, USA
Am J Manag Care 11:443-8. 2005..To document the recruitment of Medicaid and dual-enrolled Medicare beneficiaries with diabetes mellitus into a randomized clinical trial... - Current guidelines for using angiotensin-converting enzyme inhibitors and angiotensin II-receptor antagonists in chronic kidney disease: is the evidence base relevant to older adults?ANN M O'HARE
Division of Nephrology, Department of Medicine, University of Washington and Veterans Affairs Puget Sound Health Care System, Seattle, Washington 98108, USA
Ann Intern Med 150:717-24. 2009.... - Incidence and risk factors of oral antibiotic-associated diarrhea in an outpatient pediatric populationDominique Turck
Division of Gastroenterology, Hepatology and Nutrition, Department of Paediatrics, Lille University Faculty of Medicine and Children s Hospital, Lille, France
J Pediatr Gastroenterol Nutr 37:22-6. 2003..The authors' aim was to evaluate the incidence of AAD in an outpatient pediatric population and to identify risk factors... - Underlying disease severity as a major risk factor for nosocomial Clostridium difficile diarrheaLorraine Kyne
Gerontology Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Infect Control Hosp Epidemiol 23:653-9. 2002..In the future, these "high-risk" patients may benefit from prophylaxis studies of novel agents being developed to prevent C. difficile diarrhea... - What's lurking under the bed? Persistence and predominance of particular Clostridium difficile strains in a hospital and the potential role of environmental contaminationLynne V McFarland
Infect Control Hosp Epidemiol 23:639-40. 2002 - State-of-the-art of irritable bowel syndrome and inflammatory bowel disease research in 2008Lynne V McFarland
World J Gastroenterol 14:2625-9. 2008..One-quarter million people in the UK are afflicted with IBD. The cost of medical care in the United States for IBD is estimated to be 1.8 billion dollars/year...