Qian Zhu

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. ncbi request reprint Exploring the pharmacogenomics knowledge base (pharmgkb) for repositioning breast cancer drugs by leveraging web ontology language (owl) and cheminformatics approaches
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Pac Symp Biocomput 19:172-82. 2014
  2. pmc Disambiguation of PharmGKB drug-disease relations with NDF-RT and SPL
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Biomed Inform 46:690-6. 2013
  3. pmc Harmonization and semantic annotation of data dictionaries from the Pharmacogenomics Research Network: a case study
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Biomed Inform 46:286-93. 2013
  4. pmc Profiling structured product labeling with NDF-RT and RxNorm
    Qian Zhu
    Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    J Biomed Semantics 3:16. 2012
  5. pmc A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data
    Cui Tao
    Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA
    J Am Med Inform Assoc 20:554-62. 2013
  6. pmc Time-related patient data retrieval for the case studies from the pharmacogenomics research network
    Qian Zhu
    Mayo Clinic, Rochester, MN, USA
    J Med Syst 36:S37-42. 2012
  7. ncbi request reprint Standardized drug and pharmacological class network construction
    Qian Zhu
    Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    Stud Health Technol Inform 192:1125. 2013

Detail Information

Publications7

  1. ncbi request reprint Exploring the pharmacogenomics knowledge base (pharmgkb) for repositioning breast cancer drugs by leveraging web ontology language (owl) and cheminformatics approaches
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN 55905, USA
    Pac Symp Biocomput 19:172-82. 2014
    ..Our results demonstrate that combination of pharmacogenomics data and Semantic Web technology/Cheminformatics approaches yields better performance of new indication and possible adverse effects prediction for breast cancer drugs. ..
  2. pmc Disambiguation of PharmGKB drug-disease relations with NDF-RT and SPL
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Biomed Inform 46:690-6. 2013
    ..Finally, we used the detailed drug and disease relationship information from NDF-RT and the SPLs to annotate and disambiguate the more general PharmGKB drug and disease associations. ..
  3. pmc Harmonization and semantic annotation of data dictionaries from the Pharmacogenomics Research Network: a case study
    Qian Zhu
    Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
    J Biomed Inform 46:286-93. 2013
    ..This represents a critical first step toward identifying and creating data standards for pharmacogenomics studies...
  4. pmc Profiling structured product labeling with NDF-RT and RxNorm
    Qian Zhu
    Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    J Biomed Semantics 3:16. 2012
    ..abstract:..
  5. pmc A semantic-web oriented representation of the clinical element model for secondary use of electronic health records data
    Cui Tao
    Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN 55905, USA
    J Am Med Inform Assoc 20:554-62. 2013
    ..A panel evaluation has been conducted, and the results show that the OWL modeling can faithfully represent the CEM specification and represent patient data...
  6. pmc Time-related patient data retrieval for the case studies from the pharmacogenomics research network
    Qian Zhu
    Mayo Clinic, Rochester, MN, USA
    J Med Syst 36:S37-42. 2012
    ..The SPARQL query builder has been evaluated with a simulated EHR triple store to ensure its functionalities...
  7. ncbi request reprint Standardized drug and pharmacological class network construction
    Qian Zhu
    Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA
    Stud Health Technol Inform 192:1125. 2013
    ..The network consists of 39,728 drugs and drug classes. We calculated and compared structure similarity for each drug/drug class pair from ATC and NDF-RT, and analyzed constructed drug class network from chemical structure perspective. ..