Lizhi Zhang

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. doi request reprint Proposed histopathologic grading system derived from a study of KIT and CK19 expression in pancreatic endocrine neoplasm
    Lizhi Zhang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 42:324-31. 2011
  2. doi request reprint IgG4+ plasma cell infiltrates in liver explants with primary sclerosing cholangitis
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:88-94. 2010
  3. doi request reprint Autoimmune pancreatitis (AIP) type 1 and type 2: an international consensus study on histopathologic diagnostic criteria
    Lizhi Zhang
    Department of Laboratory and Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Pancreas 40:1172-9. 2011
  4. doi request reprint KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers
    Lizhi Zhang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Surg Pathol 33:1562-9. 2009
  5. pmc Autoimmune pancreatitis and IgG4-related systemic diseases
    Lizhi Zhang
    Division of Anatomic Pathology, Mayo Clinic Rochester, Minnesota, USA
    Int J Clin Exp Pathol 3:491-504. 2010
  6. doi request reprint Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy
    Amaar Ghazale
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Gastroenterology 134:706-15. 2008
  7. doi request reprint Secondary linitis plastica of the rectum: EUS features and tissue diagnosis (with video)
    Ferga C Gleeson
    Division of Gastroenterology and Hepatology, Department of Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Gastrointest Endosc 68:591-6. 2008
  8. doi request reprint Pancreatoduodenectomy for ductal adenocarcinoma: implications of positive margin on survival
    Javairiah Fatima
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arch Surg 145:167-72. 2010
  9. doi request reprint Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreas
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Surg 143:639-46; discussion 646. 2008
  10. doi request reprint Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document
    Suresh T Chari
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Pancreatology 10:664-72. 2010

Detail Information

Publications39

  1. doi request reprint Proposed histopathologic grading system derived from a study of KIT and CK19 expression in pancreatic endocrine neoplasm
    Lizhi Zhang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 42:324-31. 2011
    ..By analyzing histopathologic features in KIT/CK19 risk groups, we developed a 3-tiered histopathologic grading system using reproducible parameters (mitoses, tumor necrosis, and infiltrative border) that are easy to apply in practice...
  2. doi request reprint IgG4+ plasma cell infiltrates in liver explants with primary sclerosing cholangitis
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:88-94. 2010
    ..PSC with tissue IgG4 positivity has a more aggressive clinical course manifested by shorter time to transplant and a higher likelihood of recurrence than IgG4 negative PSC...
  3. doi request reprint Autoimmune pancreatitis (AIP) type 1 and type 2: an international consensus study on histopathologic diagnostic criteria
    Lizhi Zhang
    Department of Laboratory and Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Pancreas 40:1172-9. 2011
    ..To develop and validate histologic diagnostic criteria for autoimmune pancreatitis (AIP) and its types...
  4. doi request reprint KIT is an independent prognostic marker for pancreatic endocrine tumors: a finding derived from analysis of islet cell differentiation markers
    Lizhi Zhang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA
    Am J Surg Pathol 33:1562-9. 2009
    ..These results indicate that KIT is a new and independent prognostic marker for PETs. The classification system derived from KIT and CK19 was able to predict clinical behavior of PET...
  5. pmc Autoimmune pancreatitis and IgG4-related systemic diseases
    Lizhi Zhang
    Division of Anatomic Pathology, Mayo Clinic Rochester, Minnesota, USA
    Int J Clin Exp Pathol 3:491-504. 2010
    ..In this article, we review the literature and our own experience to detail the clinicopathologic features of AIP and extrapancreatic lesions in ISD...
  6. doi request reprint Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy
    Amaar Ghazale
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Gastroenterology 134:706-15. 2008
    ..We describe clinical features, treatment response, and predictors of relapse in IAC and compare relapse rates in IAC with intrapancreatic vs proximal bile duct strictures...
  7. doi request reprint Secondary linitis plastica of the rectum: EUS features and tissue diagnosis (with video)
    Ferga C Gleeson
    Division of Gastroenterology and Hepatology, Department of Pathology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    Gastrointest Endosc 68:591-6. 2008
    ..Luminal metastases to the GI tract may be seen at the time of the primary diagnosis or may represent evidence of a distant recurrence...
  8. doi request reprint Pancreatoduodenectomy for ductal adenocarcinoma: implications of positive margin on survival
    Javairiah Fatima
    Department of Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arch Surg 145:167-72. 2010
    ..To assess the effect of R0 resection margin status and R0 en bloc resection in pancreatoduodenectomy outcomes...
  9. doi request reprint Experience with 208 resections for intraductal papillary mucinous neoplasm of the pancreas
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Surg 143:639-46; discussion 646. 2008
    ..Intraductal papillary mucinous neoplasm (IPMN) is an increasingly recognized disease of the pancreas. We report our experience with pancreatic resection for IPMN...
  10. doi request reprint Histopathologic and clinical subtypes of autoimmune pancreatitis: the honolulu consensus document
    Suresh T Chari
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Pancreatology 10:664-72. 2010
    ..While most experts agreed that the entities should be referred to as type 1 and type 2 AIP, respectively, others had concerns regarding use of the term 'autoimmune' to describe IDCP. and IAP...
  11. ncbi request reprint IgG4-positive plasma cell infiltration in the diagnosis of autoimmune pancreatitis
    Lizhi Zhang
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Mod Pathol 20:23-8. 2007
    ..We rarely see IgG4 staining in patients with chronic alcoholic pancreatitis and pancreatic ductal adenocarcinoma. IgG4-positive plasma cells are a useful marker for the tissue diagnosis of autoimmune pancreatitis...
  12. doi request reprint Rare ALK expression but no ALK rearrangement in pancreatic ductal adenocarcinoma and neuroendocrine tumors
    Rondell P D Graham
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Pancreas 42:949-51. 2013
    ..We performed ALK immunohistochemistry on samples of pancreatic ductal adenocarcinoma and pancreatic neuroendocrine tumors using 2 tissue microarrays...
  13. ncbi request reprint Clinical characteristics and overall survival in patients with anaplastic pancreatic cancer
    Clancy J Clark
    Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, Minnesota, USA
    Am Surg 80:117-23. 2014
    ..1 versus 39.9 months, (P = 0.763). Overall survival for APC is poor; however, when resected, survival is similar to differentiated pancreatic ductal adenocarcinoma. ..
  14. pmc Adjunctive radiofrequency ablation of metastatic neuroendocrine cancer to the liver complements surgical resection
    Timucin Taner
    Departments of Surgery, Mayo Clinic, Rochester, MN 55905, USA
    HPB (Oxford) 15:190-5. 2013
    ..In this study, it was hypothesized that ablation of concomitant non-resectable NEC liver metastases is safe and salvages patients who would not have been selected for cytoreductive surgery...
  15. doi request reprint Idiopathic duct-centric pancreatitis: disease description and endoscopic ultrasonography-guided trucut biopsy diagnosis
    Michael J Levy
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN 55905, USA
    Pancreatology 11:76-80. 2011
    ..The TCB histology was definitive (n = 4) or suggestive (n = 1) for type 2 AIP. No complications developed. Conclusions: EUS-TCB may be safe and may provide sufficient material to definitively diagnose type 2 AIP. and IAP...
  16. ncbi request reprint Histopathologic and clinical subtypes of autoimmune pancreatitis: the Honolulu consensus document
    Suresh T Chari
    Mayo Clinic, Rochester, MN, USA
    Pancreas 39:549-54. 2010
    ..Whereas most experts agreed that the entities should be referred to as type 1 and type 2 AIP, respectively, others had concerns regarding use of the term "autoimmune" to describe IDCP...
  17. pmc Genetic alterations associated with progression from pancreatic intraepithelial neoplasia to invasive pancreatic tumor
    Stephen J Murphy
    Department of Molecular Medicine, Mayo Clinic, Rochester, Minnesota
    Gastroenterology 145:1098-1109.e1. 2013
    ..However, the mechanisms that control progression from PanINs to PDAC are not well understood. We investigated the genetic alterations involved in this process...
  18. doi request reprint Metastatic nonfunctioning pancreatic neuroendocrine carcinoma to liver: surgical treatment and outcomes
    Daniel Cusati
    Department of Surgery, Mayo Clinic Rochester, Rochester, MN 55905, USA
    J Am Coll Surg 215:117-24; discussion 124-5. 2012
    ..Our hypothesis was that the surgical treatment of metastatic nPNEC provides favorable perioperative and oncologic outcomes...
  19. ncbi request reprint Pancreatic intraepithelial neoplasia in heterotopic pancreas: evidence for the progression model of pancreatic ductal adenocarcinoma
    Lizhi Zhang
    Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1191-5. 2007
    ..The presence of PanIN in heterotopic pancreas from patients with ductal adenocarcinoma supports the progression model...
  20. ncbi request reprint Diagnosis of autoimmune pancreatitis: the Mayo Clinic experience
    Suresh T Chari
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 4:1010-6; quiz 934. 2006
    ..AIP has unique histologic features associated with infiltration of tissues of affected organs with abundant IgG4-positive cells. We propose expanded diagnostic criteria for AIP with a cohort of histologically confirmed AIP...
  21. ncbi request reprint Adenosquamous carcinoma of the pancreas: a single-institution experience comparing resection and palliative care
    Rory L Smoot
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    J Am Coll Surg 207:368-70. 2008
    ..Previous literature has reported dismal survival for these patients. We examined our single-institution experience with this tumor to compare survival for sugical resection and palliative therapy...
  22. pmc Diagnosis of IgG4-related tubulointerstitial nephritis
    Yassaman Raissian
    Division of Anatomic Pathology, Department of Laboratory Medicine and Pathology, Mayo Clinic, 200 1 Street SW, Rochester, MN 55905, USA
    J Am Soc Nephrol 22:1343-52. 2011
    ..When the disease manifests in the kidney, our data support diagnostic criteria that can distinguish IgG4-TIN from other types of TIN...
  23. doi request reprint Glypican-3 expression in gastrointestinal and pancreatic epithelial neoplasms
    Taofic Mounajjed
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Hum Pathol 44:542-50. 2013
    ..As these tumors commonly metastasize to the liver, this offers a potential pitfall in differentiating between HCC and metastatic carcinoma when evaluating tumors involving the liver...
  24. doi request reprint Islet-1 is a sensitive but not entirely specific marker for pancreatic neuroendocrine neoplasms and their metastases
    Rondell P Graham
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 37:399-405. 2013
    ..Our findings confirm that Isl1 is a sensitive marker of pancreatic origin in cases of metastatic NEN. However, Isl1 does not distinguish pancreatic NEN from duodenal and colorectal NEN, even when used in association with CDX2...
  25. ncbi request reprint Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma
    Benjamin R Kipp
    Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Hum Pathol 43:1552-8. 2012
    ..The results of this study are encouraging because it identifies a new potential target for genotype-directed therapeutic trials and may represent a potential biomarker for earlier detection of cholangiocarcinoma in a subset of cases...
  26. doi request reprint Histologic and imaging features of mural nodules in mucinous pancreatic cysts
    Ning Zhong
    Department of Internal Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Clin Gastroenterol Hepatol 10:192-8, 198.e1-2. 2012
    ..We assessed images and the histology of mural nodules in branch duct intraductal papillary mucinous neoplasms (BD-IPMNs) and mucinous cystic neoplasms (MCNs) and identified criteria to distinguish mural nodules from mucus...
  27. doi request reprint Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma: is cure possible?
    Thomas Schnelldorfer
    Division of Gastroenterologic and General Surgery Mayo Clinic, Rochester, MN 55905, USA
    Ann Surg 247:456-62. 2008
    ..To determine long-term survival after pancreatoduodenectomy for pancreatic ductal adenocarcinoma and to identify clinical factors associated with long-term survival...
  28. ncbi request reprint Adequacy of endoscopic ultrasound core needle biopsy specimen of nonmalignant hepatic parenchymal disease
    Ferga C Gleeson
    Fiterman Centre for Digestive Disease, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 6:1437-40. 2008
    ..Therefore, our aim was to determine the adequacy of endoscopic ultrasound (EUS)-guided Trucut liver biopsy for histopathologic evaluation to include the number of complete portal tracts contained per millimeter of acquired tissue...
  29. pmc Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice
    Zheng Fu
    Department of Urology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA
    J Clin Invest 119:2714-24. 2009
    ..These results suggest that defects in both Chfr and Mlh1 synergistically increase predisposition to tumorigenesis...
  30. pmc Poorly differentiated neuroendocrine carcinomas of the pancreas: a clinicopathologic analysis of 44 cases
    Olca Basturk
    Departments of Pathology Surgery Oncology, Memorial Sloan Kettering Cancer Center, New York, NY Department of Pathology, The Sol Goldman Pancreatic Cancer Research Center Department of Surgery, Johns Hopkins University, Baltimore, MD Department of Pathology, Emory University, Atlanta, GA Department of Pathology, Penn State Hershey MC, Hershey Department of Pathology, University of Pittsburgh, Pittsburgh, PA Department of Pathology, Ohio State University, Columbus Department of Pathology, Cleveland Clinic, Cleveland, OH Department of Pathology, Mayo Clinic, Rochester, MN Department of Pathology, University of Michigan, Ann Arbor, MI Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City, IA Department of Pathology, Indiana University, Indianapolis, IN Department of Pathology, Vanderbilt University, Nashville, TN Department of Pathology, Massachusetts General Hospital, Boston, MA Department of Pathology, Ospedale di Circolo, Varese, Italy Department of Pathology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, France
    Am J Surg Pathol 38:437-47. 2014
    ..In the pancreas, poorly differentiated neuroendocrine carcinomas include small cell carcinoma and large cell neuroendocrine carcinoma and are rare; data regarding their pathologic and clinical features are very limited...
  31. doi request reprint Endoscopic ultrasound fine-needle aspiration detection of extravascular migratory metastasis from a remotely located pancreatic cancer
    Michael J Levy
    Fiterman Centre for Digestive Disease, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, Minnesota 55905, USA
    Clin Gastroenterol Hepatol 7:246-8. 2009
    ..Our objective was to report the presence of malignant perivascular cuffing of the celiac axis in a patient with an apparently early T stage and resectable pancreatic cancer...
  32. doi request reprint Eosinophilia and allergic disorders in autoimmune pancreatitis
    Raghuwansh P Sah
    Division of Gastroenterology and Hepatology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA
    Am J Gastroenterol 105:2485-91. 2010
    ..In autoimmune pancreatitis (AIP), the prevalence, interrelationships, and significance of peripheral eosinophilia, allergic disorders, and eosinophil infiltration in the pancreas remain unclear...
  33. pmc The genomic landscape of small intestine neuroendocrine tumors
    Michaela S Banck
    Division of Medical Oncology, Mayo Clinic, Rochester, Minnesota 55905, USA
    J Clin Invest 123:2502-8. 2013
    ..We conclude that sequencing-based analysis may provide provisional grouping of SI-NETs by therapeutic targets or deregulated pathways...
  34. pmc Loss of the transcription factor GLI1 identifies a signaling network in the tumor microenvironment mediating KRAS oncogene-induced transformation
    Lisa D Mills
    Schulze Center for Novel Therapeutics, Division of Oncology Research, Rochester, Minnesota 55905, USA
    J Biol Chem 288:11786-94. 2013
    ..Collectively, these results define a novel role for GLI1 in carcinogenesis acting as a downstream effector of oncogenic KRAS in the tumor microenvironment...
  35. doi request reprint Evaluation of langerhans cell infiltrate by CD1a immunostain in liver biopsy for the diagnosis of primary biliary cirrhosis
    Rondell P D Graham
    Department of Laboratory Medicine and Pathology, Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 36:732-6. 2012
    ..In conclusion, the detection of a Langerhans cell infiltrate of ≥2 cells by CD1a in a given bile duct on needle biopsy may be a valuable tool in the diagnosis of PBC...
  36. pmc Utility of serum immunoglobulin G4 in distinguishing immunoglobulin G4-associated cholangitis from cholangiocarcinoma
    Abdul M Oseini
    Division of Gastroenterology and Hepatology, College of Medicine, Mayo Clinic and Mayo Clinic Cancer Center, Rochester, MN 55905, USA
    Hepatology 54:940-8. 2011
    ..Depending on the prevalence of the two diagnoses, the use of a 2-fold cutoff for sIgG4 may not reliably distinguish IAC from CCA. At a cutoff of 4 times the upper limit of normal, sIgG4 is 100% specific for IAC...
  37. pmc Inactivation of Brca2 promotes Trp53-associated but inhibits KrasG12D-dependent pancreatic cancer development in mice
    Matthew Rowley
    Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota
    Gastroenterology 140:1303-1313.e1-3. 2011
    ....
  38. pmc Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases
    Lizhi Zhang
    Department of Laboratory Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 34:53-64. 2010
    ..Thus, the Carney triad gastric stromal tumor is different clinically, pathologically, and behaviorally from sporadic gastric GIST...
  39. pmc USP10 regulates p53 localization and stability by deubiquitinating p53
    Jian Yuan
    Division of Oncology Research, Department of Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Cell 140:384-96. 2010
    ..These findings reveal USP10 to be a novel regulator of p53, providing an alternative mechanism of p53 inhibition in cancers with wild-type p53...