Research Topics
| Lifeng YuSummaryAffiliation: Mayo Clinic Country: USA Publications
| Collaborators
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Detail Information
Publications
Virtual monochromatic imaging in dual-source dual-energy CT: radiation dose and image qualityLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Med Phys 38:6371-9. 2011..To evaluate the image quality of virtual monochromatic images synthesized from dual-source dual-energy computed tomography (CT) in comparison with conventional polychromatic single-energy CT for the same radiation dose...
Development and validation of a practical lower-dose-simulation tool for optimizing computed tomography scan protocolsLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, MN, USA
J Comput Assist Tomogr 36:477-87. 2012..The objective of this study was to develop and validate a novel noise insertion method that can accurately simulate lower-dose images from existing standard-dose computed tomography (CT) data...- Image quality optimization and evaluation of linearly mixed images in dual-source, dual-energy CTLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Med Phys 36:1019-24. 2009.... - Metal artifact reduction from reformatted projections for hip prostheses in multislice helical computed tomography: techniques and initial clinical resultsLifeng Yu
Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Invest Radiol 44:691-6. 2009..The purpose of this work was to develop a projection-based method for reducing metal artifacts caused by hip prostheses in multislice helical CT... - Dose and image quality evaluation of a dedicated cone-beam CT system for high-contrast neurologic applicationsLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
AJR Am J Roentgenol 194:W193-201. 2010..The purpose of our study was to evaluate the dose and image quality performance of a dedicated cone-beam CT (CBCT) scanner in comparison with an MDCT scanner... 
Automatic selection of tube potential for radiation dose reduction in CT: a general strategyLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Med Phys 37:234-43. 2010..The purpose of this work was to develop a general strategy that allows for automatic tube potential selection for each individual patient and each diagnostic task...- Optimal tube potential for radiation dose reduction in pediatric CT: principles, clinical implementations, and pitfallsLifeng Yu
Department of Radiology, Mayo Clinic College of Medicine, 200 First St SW, Rochester, MN 55905, USA
Radiographics 31:835-48. 2011..The use of a lower tube potential and the amount by which to reduce radiation dose must be carefully evaluated for each type of examination to achieve an optimal tradeoff between contrast, noise, artifacts, and scanning speed... - Noise reduction to decrease radiation dose and improve conspicuity of hepatic lesions at contrast-enhanced 80-kV hepatic CT using projection space denoisingEric C Ehman
Mayo Medical School, Rochester, MN, USA
AJR Am J Roentgenol 198:405-11. 2012..The purpose of this study was to investigate the combined potential of 80-kV CT and noise reduction using a projection space denoising algorithm to reduce radiation dose reduction or to improve the image quality of hepatic CT... - Comparative study of two image space noise reduction methods for computed tomography: bilateral filter and nonlocal meansJuan C Ramirez Giraldo
CT Clinical Innovation Center, Dept of Radiology, Mayo Clinic, Rochester, MN, USA
Conf Proc IEEE Eng Med Biol Soc 2009:3529-32. 2009..Care must be taken when choosing the NLM parameters in order to minimize the generation of artifacts that could possibly compromise diagnostic value... - Region of interest reconstruction from truncated data in circular cone-beam CTLifeng Yu
Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
IEEE Trans Med Imaging 25:869-81. 2006..Quantitative results in these studies demonstrate that the proposed BPF algorithms for circular cone-beam CT can reconstruct ROI images free of truncation artifacts... - Metal artifact suppression from reformatted projections in multislice helical CT using dual-front active contoursHua Li
Department of Radiology, Mayo Clinic College of Medicine Rochester, 200 First Avenue, SW, Rochester, Minnesota 55905, USA
Med Phys 37:5155-64. 2010.... - Projection space denoising with bilateral filtering and CT noise modeling for dose reduction in CTArmando Manduca
Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Med Phys 36:4911-9. 2009..To investigate a novel locally adaptive projection space denoising algorithm for low-dose CT data... - Noise properties of chord-image reconstructionDan Xia
Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
IEEE Trans Med Imaging 26:1328-44. 2007..Additionally, it is observed that, in many situations, large data sets contain extraneous data that may not reduce the ROI-image variances... - Metal artifact suppression from reformatted projections in multi-slice helical CT using dual-front active contoursHua Li
Department of Radiology, Mayo Clinic, Rochester, MN 55901, USA
Conf Proc IEEE Eng Med Biol Soc 2009:993-6. 2009..The artifacts caused by dense metal implants were better suppressed... - Feasibility of dose reduction using novel denoising techniques for low kV (80 kV) CT enterography: optimization and validationLuis S Guimaraes
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Acad Radiol 17:1203-10. 2010..The aim of this study was to optimize and validate projection-space denoising (PSDN) strategies for application to 80-kV computed tomographic (CT) data to achieve 50% dose reduction... - A rebinned backprojection-filtration algorithm for image reconstruction in helical cone-beam CTLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Phys Med Biol 52:5497-508. 2007..We have also performed simulation studies to validate and evaluate the rebinned BPF algorithm... - Renal perfusion and hemodynamics: accurate in vivo determination at CT with a 10-fold decrease in radiation dose and HYPR noise reductionXin Liu
Department of Radiology, Divisions of Nephrology and Hypertension, CT Clinical Innovation Center, Mayo Clinic, Rochester, MN 55905, USA
Radiology 253:98-105. 2009.... - Attenuation-based estimation of patient size for the purpose of size specific dose estimation in CT. Part I. Development and validation of methods using the CT imageJia Wang
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Med Phys 39:6764-71. 2012..The ability to calculate A(w) directly from the CT image was validated with Monte Carlo simulations and an analytical model... - Attenuation-based estimation of patient size for the purpose of size specific dose estimation in CT. Part II. Implementation on abdomen and thorax phantoms using cross sectional CT images and scanned projection radiograph imagesJia Wang
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Med Phys 39:6772-8. 2012..To estimate attenuation using cross sectional CT images and scanned projection radiograph (SPR) images in a series of thorax and abdomen phantoms... - Radiation dose reduction to the breast in thoracic CT: comparison of bismuth shielding, organ-based tube current modulation, and use of a globally decreased tube currentJia Wang
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Med Phys 38:6084-92. 2011..The purpose of this work was to evaluate dose performance and image quality in thoracic CT using three techniques to reduce dose to the breast: bismuth shielding, organ-based tube current modulation (TCM) and global tube current reduction... - Quantitative imaging of element composition and mass fraction using dual-energy CT: three-material decompositionXin Liu
Mayo Clinic, Rochester, Minnesota 55905, USA
Med Phys 36:1602-9. 2009..Clinically, this may be applied to measure the mass fraction of any chemical element in a three-material mixture of solutions without the requirement of volume conservation... - Region-of-interest reconstruction of motion-contaminated data using a weighted backprojection filtration algorithmMartin King
Department of Radiology, The University of Chicago, USA
Med Phys 33:1222-38. 2006..9%. As a result of our studies, we believe that the WBPF algorithm demonstrates the potential for reconstructing quality ROI images from motion-contaminated fan-beam data... - Lowering Kilovoltage to Reduce Radiation Dose in Contrast-Enhanced Abdominal CT: Initial Assessment of a Prototype Automated Kilovoltage Selection ToolDavid M Hough
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
AJR Am J Roentgenol 199:1070-7. 2012..The purpose of this study was to determine whether the use of an automated CT kilovoltage (kV) selection tool (Auto kV) can result in lower radiation dose without sacrificing image quality in contrast-enhanced abdominopelvic CT... - Validation of dual-source single-tube reconstruction as a method to obtain half-dose images to evaluate radiation dose and noise reduction: phantom and human assessment using CT colonography and sinogram-affirmed iterative reconstruction (SAFIRE)Joel G Fletcher
Department of Radiology, Mayo Clinic, Rochester, MN, USA
J Comput Assist Tomogr 36:560-9. 2012..To evaluate a method for obtaining half-dose CT images for observer studies evaluating lower-dose CT... - A strategy to decrease partial scan reconstruction artifacts in myocardial perfusion CT: phantom and in vivo evaluationJuan C Ramirez-Giraldo
Department of Radiology, CT Clinical Innovation Center, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Med Phys 39:214-23. 2012..The purpose of this work is to present and evaluate a technique termed targeted spatial frequency filtration (TSFF) to reduce CT number variations due to PSR when applied to myocardial perfusion imaging using MDCT... - Quantification of iron in the presence of calcium with dual-energy computed tomography (DECT) in an ex vivo porcine plaque modelJia Wang
Department of Radiology, Mayo Clinic, Rochester, MN, USA
Phys Med Biol 56:7305-16. 2011..Iron quantification in the presence of calcium was feasible in excised arteries at an iron mass fraction of around 1.5% or higher using current clinical DECT scanners... - Measurement of temporal resolution in dual source CTCynthia H McCollough
Department of Radiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Med Phys 35:764-8. 2008..A demonstration of the effect of the evaluated 165 and 83 ms nominal temporal resolutions on motion artifacts in cardiac CT is provided using patient data... - Appropriate patient selection at abdominal dual-energy CT using 80 kV: relationship between patient size, image noise, and image qualityLuis S Guimaraes
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Radiology 257:732-42. 2010..To determine the computed tomographic (CT) detector configuration, patient size, and image noise limitations that will result in acceptable image quality of 80-kV images obtained at abdominal dual-energy CT... - Imaging evaluation and treatment of nephrolithiasis: an updateTerri J Vrtiska
Department of Radiology, Mayo Clinic, USA
Minn Med 93:48-51. 2010..Improvements in percutaneous therapy have led to less-invasive and less-costly treatments for nephrolithiasis. This article describes some of these new approaches to diagnosing and caring for patients with renal stone disease... - Spatial-resolution enhancement in computed tomographyXiaochuan Pan
Department of Radiology, The University of Chicago, Chicago, IL 60637, USA
IEEE Trans Med Imaging 24:246-53. 2005..The proposed acquisition/reconstruction approach may find applications in micro-CT and industrial CT in which the CORs may be changed... - Noise reduction in spectral CT: reducing dose and breaking the trade-off between image noise and energy bin selectionShuai Leng
Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Med Phys 38:4946-57. 2011..Our purpose was to reduce image noise in spectral CT by exploiting data redundancies in the energy domain to allow flexible selection of the number, width, and location of the energy bins... - Strategies for reducing radiation dose in CTCynthia H McCollough
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Radiol Clin North Am 47:27-40. 2009..To satisfy the ALARA principle, the dose reduction strategies described in this article must be well understood and properly used. The use of CT must also be justified for the specific diagnostic task... - Genitourinary applications of dual-energy CTTerri J Vrtiska
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
AJR Am J Roentgenol 194:1434-42. 2010..CONCLUSION: Dual-energy CT is beginning to play an important role in patients with genitourinary diseases by providing unique characterization tools for calculi and masses... - Achieving routine submillisievert CT scanning: report from the summit on management of radiation dose in CTCynthia H McCollough
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
Radiology 264:567-80. 2012.... - A unified analysis of FBP-based algorithms in helical cone-beam and circular cone- and fan-beam scansXiaochuan Pan
Department of Radiology, The University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
Phys Med Biol 49:4349-69. 2004..We also performed a preliminary numerical study to verify our theoretical results in each of the cases. The results in the work can readily be generalized to other non-circular trajectories... - Dual-energy and dual-source CT: is there a role in the abdomen and pelvis?Joel G Fletcher
Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Radiol Clin North Am 47:41-57. 2009..This article summarizes and reviews current and potential applications for dual-energy and dual-source CT in the abdomen and pelvis... - Prediction of human observer performance in a 2-alternative forced choice low-contrast detection task using channelized Hotelling observer: Impact of radiation dose and reconstruction algorithmsLifeng Yu
Department of Radiology, Mayo Clinic, Rochester, Minnesota 55905
Med Phys 40:041908. 2013..3% for IR.Conclusions: Human observer performance on a 2AFC lesion detection task in CT with a uniform background can be accurately predicted by a CHO model observer at different radiation dose levels and for both FBP and IR methods... - Dual-Energy CT-Based Monochromatic ImagingLifeng Yu
Department of Radiology, Mayo Clinic, 200 First St SW, Rochester, MN 55905
AJR Am J Roentgenol 199:S9-S15. 2012.... - CT scanner x-ray spectrum estimation from transmission measurementsXinhui Duan
Department of Radiology, Mayo Clinic, 200 First Street Southwest, Rochester, Minnesota 55905, USA
Med Phys 38:993-7. 2011..The expectation maximization (EM) method is an accurate and robust method to solve this problem. In this article, this method was evaluated in a commercial CT scanner... - Image reconstruction with shift-variant filtration and its implication for noise and resolution properties in fan-beam computed tomographyXiaochuan Pan
Department of Radiology, MC2026, The University of Chicago, Chicago, Illinois 60637, USA
Med Phys 30:590-600. 2003.... - Half-scan fan-beam computed tomography with improved noise and resolution propertiesLifeng Yu
Department of Radiology, MC2026, 5841 S. Maryland Avenue, The University of Chicago, Chicago, Illinois 60637, USA
Med Phys 30:2629-37. 2003..The analytic results of the image-noise properties can be used for image-quality assessment in detection/classification tasks by use of model-observers... - Radiation dose reduction for CT-guided renal tumor cryoablationShuai Leng
Department of Radiology, Mayo Clinic, Rochester, MN 55905, USA
AJR Am J Roentgenol 196:W586-91. 2011..The purpose of this article is to retrospectively determine the image quality and degree of radiation dose reduction that is clinically acceptable for CT-guided renal tumor cryoablation...