Affiliation: Mayo Clinic
Country: USA


  1. Olthof M, Lu L, Tryfonidou M, Loozen L, Pouran B, Yaszemski M, et al. The osteoinductive effect of controlled BMP-2 release is location-dependent. Tissue Eng Part A. 2018;: pubmed publisher
    ..Additionally, more bone formation in OPF-BP compared to ACS at both application sites emphasizes the role of biomaterials as a scaffold to achieve proper bone tissue formation. ..
  2. Olthof M, Tryfonidou M, Dadsetan M, Dhert W, Yaszemski M, Kempen D, et al. In Vitro and In Vivo Correlation of BMP-2 Release Profiles from Complex Delivery Vehicles. Tissue Eng Part C Methods. 2018;: pubmed publisher
    ..Altogether, these results imply that more sophisticated in vitro systems should be used in bone regeneration to accurately discriminate and predict in vivo BMP-2 release from different complex delivery vehicles. ..
  3. Dadsetan M, Guda T, Runge M, Mijares D, Legeros R, LeGeros J, et al. Effect of calcium phosphate coating and rhBMP-2 on bone regeneration in rabbit calvaria using poly(propylene fumarate) scaffolds. Acta Biomater. 2015;18:9-20 pubmed publisher
  4. Ciubuc J, Manciu M, Maran A, Yaszemski M, Sundin E, Bennet K, et al. Raman Spectroscopic and Microscopic Analysis for Monitoring Renal Osteodystrophy Signatures. Biosensors (Basel). 2018;8: pubmed publisher
    ..This work thus opens the possibility of future development of in vivo Raman sensors for assessment of bone structure, remodeling, and mineralization, where different biomarkers are simultaneously detected with unprecedented accuracy. ..
  5. Maran A, Yaszemski M, Kohut A, Voronov A. Curcumin and Osteosarcoma: Can Invertible Polymeric Micelles Help?. Materials (Basel). 2016;9: pubmed publisher
    ..The potential of micellar assemblies from responsive macromolecules in a controlled delivery of curcumin to osteosarcoma cells, and the release using a new inversion mechanism is revealed. ..
  6. Olthof M, Tryfonidou M, Liu X, Pouran B, Meij B, Dhert W, et al. Phosphate functional groups improve OPF osteoconduction and BMP-2 osteoinductive efficacy. Tissue Eng Part A. 2017;: pubmed publisher
    ..Therefore, functionalizing hydrogels with phosphate groups by crosslinking monomers into the hydrogel matrix could provide a valuable method for improving polymer characteristics and hold great promise for bone tissue engineering. ..