Research Topics
| R S WrightSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Long-term prognosis of patients with clinical unstable angina pectoris without elevation of creatine kinase but with elevation of cardiac troponin i levelsRonnier J Aviles
Division of Cardiovascular Medicine, The Mayo Medical School, Rochester, Minnesota 55905, USA
Am J Cardiol 90:875-8. 2002
Preoperative aspirin therapy is associated with improved postoperative outcomes in patients undergoing coronary artery bypass graftingKevin A Bybee
Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, MN, USA
Circulation 112:I286-92. 2005....
Cardiac catheterization reduces resource utilization in patients with chronic chest painR S Wright
Mayo Physician Alliance for Clinical Trials Coordinating Center, Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA
Catheter Cardiovasc Interv 49:363-6. 2000..These results may decrease the use of expensive medical resources and encourage full occupational and lifestyle rehabilitation...
Reduced risks of death and CHF are associated with statin therapy administered acutely within the first 24 h of AMIR Scott Wright
Division of Cardiology, Department of Internal Medicine, USA
Int J Cardiol 108:314-9. 2006..There are little data about whether early statin therapy reduces risk of CHF and alters timing of death...
Statin lipid-lowering therapy for acute myocardial infarction and unstable angina: efficacy and mechanism of benefitR Scott Wright
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 77:1085-92. 2002..A body of evidence suggests that the pleiotropic actions of statin agents might modulate benefit in ACS. This article summarizes the available data and provides a rationale for early initiation of statin therapy for patients with ACS...
Acute myocardial infarction and renal dysfunction: a high-risk combinationR Scott Wright
Division of Cardiology, Mayo Alliance for Clinical Trials, Mayo Clinic, Stabile 5, 150 Third Street SW, Rochester, MN 55902, USA
Ann Intern Med 137:563-70. 2002..Survival is poor in patients with acute myocardial infarction (MI) who also have severe renal disease. Less is known about the outcome of acute MI in patients with mild to moderate renal insufficiency...
Elevations of cardiac troponin I are associated with increased short-term mortality in noncardiac critically ill emergency department patientsR Scott Wright
Division of Cardiology, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota, USA
Am J Cardiol 90:634-6. 2002
Update on intravenous fibrinolytic therapy for acute myocardial infarctionR S Wright
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 75:1185-91; quiz 1192. 2000....
Characteristics of presenting electrocardiograms of acute myocardial infarction from a community-based population predict short- and long-term mortalityW L Miller
Coronary Care Unit Group, Mayo Clinic and Mayo Foundation, Division of Cardiovascular Diseases, Department of Internal Medicine, Rochester, Minnesota 55905, USA
Am J Cardiol 87:1045-50. 2001..Among non-LBBB groups, ST-segment depression with or without ST elevation was associated with increased short-term mortality. Also, in this community-based population, 18.5% of patients had normal or nondiagnostic electrocardiograms...
False-negative and false-positive ECG diagnoses of Q wave myocardial infarction in the presence of right bundle-branch blockI Gussak
Mayo Physician Alliance for Clinical Trials, Mayo Clinic Stabile 5, 150 Third Street SW, Rochester, MN 55902, USA
Cardiology 94:165-72. 2000..Further investigations are warranted to better delineate sensitivity, specificity, and predictive value of Q wave MI in the presence of RBBB...
Bundle branch block as a predictor of long-term survival after acute myocardial infarctionE S Brilakis
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Cardiol 88:205-9. 2001..Our conclusion from this study is that in a community-based population, patients who had LBBB or RBBB at the time of AMI had lower predischarge ejection fractions and higher in-hospital and long-term unadjusted mortality...
A new simplified immediate prognostic risk score for patients with acute myocardial infarctionB A Williams
Division of Biostatistics, Mayo Clinic and Foundation, Rochester, MN, USA
Emerg Med J 23:186-92. 2006..The present results suggest that even amidst changing patient profiles, treatment, and disease definitions, the Mayo model is useful for 30 day risk assessment following AMI...
Effect of concomitant or very early statin administration on in-hospital mortality and reinfarction in patients with acute myocardial infarctionK A Bybee
Department of Internal Medicine, Mayo Physician Alliance for Clinical Trials, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Am J Cardiol 87:771-4, A7. 2001..End points of in-hospital mortality and in-hospital reinfarction were significantly lower in the statin-treated group, pointing to a benefit from very early statin treatment in acute myocardial infarction...
Exercise-induced ST segment elevation in Q wave leads in postinfarction patients: defining its meaning and utility in today's practiceI Gussak
Mayo Physician Alliance for Clinical Trials, Rochester, MN 55905, USA
Cardiology 93:205-9. 2000..In the era of sophisticated nuclear and echo techniques, accurate imaging studies should not be replaced by ECG analysis alone in the search for viable tissue, except when financial costs are of major importance...
Obesity is associated with premature occurrence of acute myocardial infarctionJ A Suwaidi
Coronary Care Unit Group and the Mayo Physician Alliance for Clinical Trials (MPACT, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55902, USA
Clin Cardiol 24:542-7. 2001..CONCLUSION: In this population-based study, overweight and obese status are independently associated with the premature occurrence of AMI, but not with an increased incidence of in-hospital complications...
Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndromeKevin A Bybee
Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Am J Cardiol 94:343-6. 2004..TIMI frame counts were abnormal in all patients and often abnormal in all 3 major coronary vessels, suggesting that the diffuse impairment of coronary microcirculatory function may play a role in the pathogenesis of the syndrome...
Baseline comorbidities and treatment strategy in elderly patients are associated with outcome of cardiogenic shock in a community-based populationJames V Tedesco
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Am Heart J 146:472-8. 2003....
Strong predictive value of TIMI risk score analysis for in-hospital and long-term survival of patients with right ventricular infarctionR J Gumina
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Eur Heart J 23:1678-83. 2002..006). CONCLUSIONS: In-hospital morbidity and mortality, and long-term mortality are increased by right ventricular infarction and can be accurately predicted by the initial TIMI risk score...
Initial approach to the patient who has chest painLuis H Haro
Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Cardiol Clin 24:1-17, v. 2006....
Eosinophilic-lymphocytic myocarditis after smallpox vaccinationJoseph G Murphy
Division of Cardiovascular Diseases, Mayo Clinic and Foundation, 200 First Street SW, Rochester, MN 55905, USA
Lancet 362:1378-80. 2003..A better understanding of the aberrant immune mechanism of myocyte injury after smallpox vaccination might improve the risk/benefit assessment for people considering smallpox vaccination and better smallpox vaccines in the future...
Percutaneous closure of left ventricular-to-right atrial fistula after prosthetic mitral valve rereplacement using the Amplatzer duct occluderAllison K Cabalka
Division of Pediatric Cardiology, Mayo Clinic, Rochester, MN 55905, USA
Catheter Cardiovasc Interv 64:522-7. 2005..We report the novel use of the Amplatzer duct occluder for closure of the fistulous tract...
Effect of diabetes on the mortality risk of cardiogenic shock in a community-based populationJames V Tedesco
Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Mayo Clin Proc 78:561-6. 2003....
Influence of preoperative lipid-lowering therapy on postoperative outcome in patients undergoing coronary artery bypass graftingBrian D Powell
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 99:785-9. 2007..However, patient risk factors and other cardioprotective medication use associated with the use of preoperative lipid-lowering therapy appear to explain the association with improved survival...
Impact of community-based education on health care evaluation in patients with acute chest pain syndromes: the Wabasha Heart Attack Team (WHAT) projectR S Wright
Division of Cardiovascular Diseases and the Mayo Physician Alliance for Clinical Trials (MPACT) Coordinating Center, Mayo Clinic and Mayo Foundation, Rochester, MN 55902, USA
Fam Pract 18:537-9. 2001..05). CONCLUSION: A community education campaign can significantly increase use of pre-hospital emergency medical service resources and may increase the number of patients presenting with acute chest pain symptoms, including MI...
Suspected ventilator-associated pneumonia in cardiac patients admitted to the coronary care unitS Allen Ensminger
Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester, Minn. 55905, USA
Mayo Clin Proc 81:32-5. 2006..The development of VAP in CCU patients is associated with a prolonged CCU stay but not with an increased hospital mortality...
Noninvasive estimation of left ventricular filling pressure by E/e' is a powerful predictor of survival after acute myocardial infarctionGraham S Hillis
Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Am Coll Cardiol 43:360-7. 2004..An E/e' ratio >15 is superior, in this respect, to other clinical or echocardiographic features. Furthermore, it provides prognostic information incremental to these parameters...
Comparison of intravenous myocardial contrast echocardiography and low-dose dobutamine echocardiography for predicting left ventricular functional recovery following acute myocardial infarctionGraham S Hillis
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Cardiol 92:504-8. 2003..Low-dose DE was superior to intravenous MCE in the prediction of functional recovery of akinetic myocardium after AMI, but the combination of both maximizes predictive accuracy...
Association of the PURSUIT risk score with predischarge ejection fraction, angiographic severity of coronary artery disease, and mortality in a nonselected, community-based population with non-ST-elevation acute myocardial infarctionEmmanouil S Brilakis
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
Am Heart J 146:811-8. 2003..77) mortality. CONCLUSIONS: The PURSUIT risk score correlates with EF, angiographic severity of coronary artery disease, and short- and long-term mortality of nonselected patients with non-ST-elevation acute myocardial infarction...
Left atrial volume: a powerful predictor of survival after acute myocardial infarctionJacob E Moller
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, Minn 55905, USA
Circulation 107:2207-12. 2003..CONCLUSIONS: Increased LA volume index is a powerful predictor of mortality after AMI and provides prognostic information incremental to clinical data and conventional measures of LV systolic and diastolic function...
Idiopathic short QT interval: a new clinical syndrome?I Gussak
Mayo Physician Alliance for Clinical Trials, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Cardiology 94:99-102. 2000..Our report also describes other manifestations of abnormal shortening of the QTI and considers the possible arrhythmogenic potential of the short QTI...
Superior short-term cholesterol control and achievement of the adult treatment panel III low-density lipoprotein goals with initiation of statin therapy by the time of hospital discharge following acute myocardial infarctionKevin A Bybee
Division of Biostatistics, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
Am J Cardiol 93:776-9. 2004..56; p <0.01)...
Long-term survival after right ventricular infarctionRichard J Gumina
Division of Cardiovascular Diseases, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Am J Cardiol 98:1571-3. 2006..In conclusion, RVMI is associated with substantial first-year mortality, which decreases to a much lower attrition rate between years 1 and 10, with no greater long-term mortality in those patients with concomitant LCA disease...
Systematic review: transient left ventricular apical ballooning: a syndrome that mimics ST-segment elevation myocardial infarctionKevin A Bybee
Mayo Clinic College of Medicine, Rochester, Minnesota, USA
Ann Intern Med 141:858-65. 2004..An episode of emotional or physiologic stress frequently precedes presentation with the syndrome. The in-hospital mortality rate seems to be low, as does the risk for recurrence...
Effect of early statin therapy after acute coronary syndromes: a concise review of the recent dataKevin A Bybee
Instructor of Medicine, Mayo Medical School, and Fellow in Cardiovascular Diseases, Rochester, Minnesota 55902, USA
Cardiol Rev 10:301-5. 2002..This paper reviews the available data from randomized-controlled trials and observational studies evaluating the effect of early statin initiation during, or soon following, an acute coronary syndrome...
Low-dose nesiritide in human anterior myocardial infarction suppresses aldosterone and preserves ventricular function and structure: a proof of concept studyH H Chen
Cardiorenal Research Laboratory, Mayo Clinic, Rochester, MN 55904, USA
Heart 95:1315-9. 2009....
Excess weight at time of presentation of myocardial infarction is associated with lower initial mortality risks but higher long-term risks including recurrent re-infarction and cardiac deathAnil Nigam
Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Int J Cardiol 110:153-9. 2006..Younger age at the time of initial infarction and fewer non-cardiovascular comorbidities presumably explain the short-lived obesity survival paradox following myocardial infarction...
Four-year recurrence rate and prognosis of the apical ballooning syndromeAhmad A Elesber
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 50:448-52. 2007..This study sought to assess the long-term prognosis of patients with apical ballooning syndrome (ABS)...
Ventricular septal hamartoma mimicking hypertrophic cardiomyopathy in a 41-year-old woman presenting with paroxysmal supraventricular tachycardiaGregory Gilman
Division of Cardiovascular Diseases, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
J Am Soc Echocardiogr 18:272-4. 2005..This report confirms the use of transthoracic echocardiography as a screening tool in the diagnosis and management of an uncommon case of a benign cardiac tumor...
Prevalence of diabetic peripheral neuropathy and relation to glycemic control therapies at baseline in the BARI 2D cohortRodica Pop-Busui
Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI 48109, USA
J Peripher Nerv Syst 14:1-13. 2009....
Electrocardiography cannot reliably differentiate transient left ventricular apical ballooning syndrome from anterior ST-segment elevation myocardial infarctionKevin A Bybee
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Electrocardiol 40:38.e1-6. 2007..We tested the hypothesis that the ECG on presentation could reliably differentiate these syndromes...
Cardiac amyloidosis presenting with elevations of cardiac troponin I and angina pectorisRyan V Cantwell
Mayo Clinic and Foundation, Department of Internal Medicine, Rochester, Minnesota 55905, USA
Clin Cardiol 25:33-7. 2002..The electron microscopy in our case confirms cardiac damage as the mechanism for cTnI elevation. This observation strengthens our knowledge about the specificity of cTnI for the detection of cardiac injury...
Acute impairment of regional myocardial glucose uptake in the apical ballooning (takotsubo) syndromeKevin A Bybee
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
J Nucl Cardiol 13:244-50. 2006..CONCLUSION: In all 4 patients, affected regions subsequently recovered regional LV systolic function within 6 weeks...
Hormone replacement therapy and risk of acute myocardial infarction in postmenopausal women with diabetes mellitusApoor S Gami
Department of Internal Medicine, The Mayo Alliance for Clinical Trials, Rochester, Minnesota 55905, USA
Am J Cardiol 91:1275-7. 2003
Effects of early treatment with statins on short-term clinical outcomes in acute coronary syndromes: a meta-analysis of randomized controlled trialsMatthias Briel
Basel Institute for Clinical Epidemiology, University Hospital Basel, Basel, Switzerland
JAMA 295:2046-56. 2006..CONCLUSION: Based on available evidence, initiation of statin therapy within 14 days following onset of ACS does not reduce death, MI, or stroke up to 4 months...
Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: national registry of myocardial infarctionFrederick A Spencer
Division of Cardiovascular Medicine, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Arch Intern Med 164:2162-8. 2004..It has been suggested that withdrawal of statin therapy during an acute coronary syndrome may attenuate any benefits of pretreatment, thereby providing indirect evidence of the importance of their non-lipid-lowering effects...
ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise thJeffrey L Anderson
J Am Coll Cardiol 50:e1-e157. 2007
Renal insufficiency and worsened prognosis with STEMI: a call for actionWilliam J French
J Am Coll Cardiol 42:1544-6. 2003
Effect of statin use within the first 24 hours of admission for acute myocardial infarction on early morbidity and mortalityGregg C Fonarow
The Ahmanson UCLA Cardiomyopathy Center, UCLA Division of Cardiology, Los Angeles, California, USA
Am J Cardiol 96:611-6. 2005..0001). In conclusion, the use of statin therapy within the first 24 hours of hospitalization for AMI is associated with a significantly lower rate of early complications and in-hospital mortality...
Prognostic value of the erythrocyte sedimentation rate in patients with unstable anginaLambert A Wu
Arch Pathol Lab Med 126:772. 2002
Pox, patient, and plaqueJoseph G Murphy
Vaccine 26:2175-6. 2008
Pathophysiology, diagnosis, and management of dyslipidemiaGerald T Gau
Mayo College of Medicine, USA
Curr Probl Cardiol 31:445-86. 2006..The clinical interaction with novel risk factors and the practical problems in patient management are discussed...
ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise thJeffrey L Anderson
Circulation 116:e148-304. 2007
