Research Topics
| Bruce G WolffSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Prophylactic resection, uncomplicated diverticulitis, and recurrent diverticulitisBruce G Wolff
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
Dig Dis 30:108-13. 2012..Ischemic colitis is also in the differential diagnosis, and many patients who have diverticulitis, have irritable bowel syndrome as well, so caution must be used in predicting positive outcomes after surgery in these patients...
Is ileoanal the proper operation for indeterminate colitis: the case forBruce G Wolff
Mayo Clinic, Rochester, Minnesota 55905, USA
Inflamm Bowel Dis 8:362-5; discussion 368-9. 2002- Postoperative ileus-related morbidity profile in patients treated with alvimopan after bowel resectionBruce G Wolff
Division of Colon and Rectal Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Am Coll Surg 204:609-16. 2007..The effect of alvimopan on POI-related morbidity for patients who underwent bowel resection was evaluated in a post-hoc analysis... - "Latch on to the affirmative: don't mess with Mr. In-Between"Bruce G Wolff
Division of Colon Rectal Surgery, Mayo Foundation, 200 First Street SW, Rochester, Minnesota 55905, USA
Dis Colon Rectum 49:547-56. 2006 
Alvimopan, a novel, peripherally acting mu opioid antagonist: results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial of major abdominal surgery and postoperative ileusBruce G Wolff
Mayo Clinic, Rochester, MN, USA
Ann Surg 240:728-34; discussion 734-5. 2004..To demonstrate that alvimopan (6 or 12 mg) accelerates recovery of gastrointestinal (GI) function in patients undergoing laparotomy for bowel resection or radical hysterectomy...- Impact of pelvic radiotherapy on morbidity and durability of sphincter preservation after coloanal anastomosis for rectal cancersImran Hassan
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Dis Colon Rectum 51:32-7. 2008..This study was designed to assess the impact of pelvic radiotherapy on the incidence of complications and colostomy-free survival of patients after a coloanal anastomosis for rectal cancer... - Splenic salvage after intraoperative splenic injury during colectomyStefan D Holubar
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Arch Surg 144:1040-5. 2009..To determine the optimal surgical management of splenic injury encountered during colectomy... - Effect of infliximab on short-term complications in patients undergoing operation for chronic ulcerative colitisChelliah R Selvasekar
Division of Colon and Rectal Surgery, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Am Coll Surg 204:956-62; discussion 962-3. 2007..Infliximab (IFX), an antitumor necrosis factor-alpha antibody, has demonstrated efficacy in medical management of CUC. The aim of this study is to determine if IFX before IPAA impacts short-term outcomes... - Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancerImran Hassan
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Dis Colon Rectum 49:1266-74. 2006..Loss of intestinal continuity after a coloanal anastomosis is associated with diminished quality of life... - Long-term direct costs before and after proctocolectomy for ulcerative colitis: a population-based study in Olmsted County, MinnesotaStefan D Holubar
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Dis Colon Rectum 52:1815-23. 2009..This study was designed to test the hypothesis that patients undergoing definitive surgery for chronic ulcerative colitis have reduced direct medical costs after, as compared with before, total proctocolectomy... - Sexual function, body image, and quality of life after laparoscopic and open ileal pouch-anal anastomosisDavid W Larson
Division of Colon and Rectal Surgery, Mayo Clinic Rochester, Rochester, MN 55905, USA
Dis Colon Rectum 51:392-6. 2008..This study was designed to compare self-reported sexual function, body image, and quality of life outcomes among ulcerative colitis patients undergoing laparoscopic or open ileal pouch-anal anastomosis... - Postoperative morbidity with diversion after low anterior resection in the era of neoadjuvant therapy: a single institution experienceVassiliki L Tsikitis
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
J Am Coll Surg 209:114-8. 2009.... - Diagnoses influence surgical site infections (SSI) in colorectal surgery: a must consideration for SSI reporting programs?Rajesh Pendlimari
Department of General Surgery, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN 55901, USA
J Am Coll Surg 214:574-80; discussion 580-1. 2012..Patient stratification and risk adjustment are associated with Current Procedural Terminology codes and primary disease diagnosis is not considered. Our aim was to determine the association between disease diagnosis and SSI rates... - Outcomes in patients with ulcerative colitis undergoing partial or complete reconstructive surgery for failing ileal pouch-anal anastomosisKellie L Mathis
Department of Surgery, Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Ann Surg 249:409-13. 2009..Evaluate outcomes of patients with an original diagnosis of ulcerative colitis (UC) who required partial or complete ileal pouch reconstruction due to poor function or infectious complications... - The use of human acellular dermal matrix for parastomal hernia repair in patients with inflammatory bowel disease: a novel technique to repair fascial defectsTimucin Taner
Division of Gastrointestinal and General Surgery, Mayo Clinic, Rochester, Minnesota, USA
Dis Colon Rectum 52:349-54. 2009..The tissue weakness at the site of hernia can be overcome by creating neofascia using two separate layers of human acellular dermal matrix... - Quality of life after ileal pouch-anal anastomosis and ileorectal anastomosis in patients with familial adenomatous polyposisImran Hassan
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Dis Colon Rectum 48:2032-7. 2005.... - Synchronous rectal and hepatic resection of rectal metastatic diseaseSarah York Boostrom
Division of Gastroenterologic Surgery, Mayo Clinic, Rochester, MN 55905, USA
J Gastrointest Surg 15:1583-8. 2011..The objectives were to determine the feasibility of combined rectal and hepatic resections and analyze the disease-free survival and overall survival... - Survival in stage III colon cancer is independent of the total number of lymph nodes retrievedVassiliki L Tsikitis
Division of Colorectal Surgery, Mayo Clinic, Rochester, MN, USA
J Am Coll Surg 208:42-7. 2009..The aim of our study was to determine if increasing the number of lymph nodes recovered in stage III colon cancer results in improved survival and if it does represent a reasonable quality metric... - Early postoperative complications are not increased in patients with Crohn's disease treated perioperatively with infliximab or immunosuppressive therapyJean Frederic Colombel
Division of Gastroenterology and Hepatology, Division of Colorectal Surgery, and Section of Biostatistics, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 99:878-83. 2004..The aim was to determine whether the use of steroids, immunosuppressive agents, or infliximab prior to abdominal surgery for Crohn's disease is associated with an increased rate of early postoperative complications... - Utility and short-term outcomes of hand-assisted laparoscopic colorectal surgery: a single-institution experience in 1103 patientsRobert R Cima
Division of Colon and Rectal Surgery, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Dis Colon Rectum 54:1076-81. 2011..Hand-assisted laparoscopic colectomy is an alternative technique that addresses these problems while preserving the short-term benefits of laparoscopic colectomy... - Laparoscopic-assisted vs. open ileal pouch-anal anastomosis: functional outcome in a case-matched seriesDavid W Larson
Division of Colon and Rectal Surgery, Mayo Clinic Rochester, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Dis Colon Rectum 48:1845-50. 2005..Laparoscopic-assisted ileal pouch-anal anastomosis offers selected patients a safe, feasible, and durable alternative... - Clinical features and oncologic outcomes in patients with rectal cancer and ulcerative colitis: a single-institution experienceAmit Merchea
Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA
Dis Colon Rectum 55:881-5. 2012..Limited data exists in ulcerative colitis patients with rectal cancer regarding clinical and oncologic outcomes, and the ideal operative approach... - Diverticulitis: a progressive disease? Do multiple recurrences predict less favorable outcomes?Jennifer R Chapman
Division of Colon and Rectal Surgery, Mayo Clinic and Mayo Foundation, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Ann Surg 243:876-830; discussion 880-3. 2006..Practice parameters recommend elective resection after 2 episodes of diverticulitis to reduce this morbidity and mortality... - Long-term quality of life and sexual and urinary function after abdominoperineal resection for distal rectal cancerMichael S Kasparek
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Dis Colon Rectum 55:147-54. 2012.... - Patterns of gastrointestinal recovery after bowel resection and total abdominal hysterectomy: pooled results from the placebo arms of alvimopan phase III North American clinical trialsBruce G Wolff
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, and Department of Anesthesiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, USA
J Am Coll Surg 205:43-51. 2007.... - Ileal pouch-anal anastomosis: does age at the time of surgery affect outcome?Jennifer R Chapman
Division of Colorectal Surgery and the Department of Biostatistics, Mayo Clinic and Mayo Foundation, Mayo Clinic College of Medicine, Rochester, Minn, USA
Arch Surg 140:534-9; discussion 539-40. 2005..Our aim was to update our understanding on how the age of the patient at the time of surgery influences functional outcome and quality of life after IPAA... - Perioperative anti-tumor necrosis factor therapy does not increase the rate of early postoperative complications in Crohn's diseaseBasil S Nasir
Division of Colon and Rectal Surgery, Mayo Clinic College of Medicine, Rochester, MN, USA
J Gastrointest Surg 14:1859-65; discussion 1865-6. 2010..The aim of our study was to examine the rate of postoperative morbidity in patients receiving anti TNF therapy in the perioperative period... - Primary intestinal lymphoma in patients with inflammatory bowel disease: a descriptive series from the prebiologic therapy eraStefan D Holubar
Division of Colon and Rectal Surgery, Dartmouth Hitchcock Medical Center, Lebanon NH 03756, USA
Inflamm Bowel Dis 17:1557-63. 2011..We report clinical features and outcomes in patients with both conditions prior to use of biologic therapy... - The effect of ageing on function and quality of life in ileal pouch patients: a single cohort experience of 409 patients with chronic ulcerative colitisDieter Hahnloser
Division of Colon and Rectal Surgery, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN, USA
Ann Surg 240:615-21; discussion 621-3. 2004..These data support the conclusion that IPAA is a durable operation for patients requiring proctocolectomy for CUC; functional and QoL outcomes are good, predictable, and stable for 15 years after operation... - Partial pathologic response and nodal status as most significant prognostic factors for advanced rectal cancer treated with preoperative chemoradiotherapyMarianne Huebner
Division of Health Sciences Research, Mayo Clinic, Rochester, MN, USA
World J Surg 36:675-83. 2012..The value of a grading less than pCR for predicting survival is unknown. Tumor budding has not been systematically studied in rectal cancer after neoadjuvant therapy... - Management and outcomes of primary coloduodenal fistulasAshwin S Kamath
Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, MN, USA
J Gastrointest Surg 15:1706-11. 2011..Primary coloduodenal fistula (CDF) is a rare entity. We review our experience with the management and outcomes of CDF... - Sacral osteomyelitis after ileal pouch-anal anastomosis: report of four casesWilliam E Taylor
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Dis Colon Rectum 49:913-8. 2006..With more aggressive treatment comprising sacral debridement, long-term antibiotics, and fecal diversion, pouch function can potentially be preserved... - Risk factors for splenic injury during colectomy: a matched case-control studyJeffrey K Wang
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
World J Surg 35:1123-9. 2011..We assessed risk factors for splenic injury during colectomy and associated outcomes for a 15-year period at a single institution... - Concurrent vs. staged colectomy and hepatectomy for primary colorectal cancer with synchronous hepatic metastasesHeidi K Chua
Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Dis Colon Rectum 47:1310-6. 2004..001). CONCLUSIONS: Concurrent colectomy and hepatectomy is safe and more efficient than staged resection and should be the procedure of choice for selected patients in medical centers with appropriate capacity and experience... - Experience with 969 minimal access colectomies: the role of hand-assisted laparoscopy in expanding minimally invasive surgery for complex colectomiesRobert R Cima
Division of Colon and Rectal Surgery, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Am Coll Surg 206:946-50; discussion 950-2. 2008..Hand-assisted laparoscopy (HALS) permits placement of a hand into the abdomen to assist the dissection. Our aim was to analyze the impact of HALS on a minimal access colectomy (MAC) practice... - Uncomplicated diverticulitis, more complicated than we thoughtSarah Y Boostrom
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
J Gastrointest Surg 16:1744-9. 2012..The classification of complicated and uncomplicated diverticulitis has been used for many years. We note variations in the course of uncomplicated diverticulitis. We propose and describe three categories of uncomplicated diverticulitis... - Immediate radical resection after local excision of rectal cancer: an oncologic compromise?Dieter Hahnloser
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Dis Colon Rectum 48:429-37. 2005..The aim of this study was to determine the frequency and outcome of radical resection (within 30 days) after local excision for rectal adenocarcinoma... - Maternal and fetal outcome after colectomy for fulminant ulcerative colitis during pregnancy: case series and literature reviewEric J Dozois
Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
Dis Colon Rectum 49:64-73. 2006..This study was designed to assess the maternal and fetal outcomes of pregnant females undergoing colectomy for ulcerative colitis in the current era... - Surgical treatment of complex enterocutaneous fistulas in IBD patients using human acellular dermal matrixTimucin Taner
Division of Gastrointestinal and General Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Inflamm Bowel Dis 15:1208-12. 2009..Herein we report the use human acellular dermal matrix (hADM) in the surgical treatment and reconstruction of the abdominal wall in 11 consecutive IBD patients with complex and medically refractory ECF... - Short- and long-term surgical outcomes in patients undergoing proctocolectomy with ileal pouch-anal anastomosis in the setting of primary sclerosing cholangitisKellie L Mathis
Mayo Clinic, Department of Surgery, Division of Colon and Rectal Surgery, Rochester, Minnesota, USA
Dis Colon Rectum 54:787-92. 2011..Primary sclerosing cholangitis occurs in approximately 10% of patients with ulcerative colitis, but studies involving IPAA in patients with cholangitis have been reported in limited numbers... - Pregnancy and delivery before and after ileal pouch-anal anastomosis for inflammatory bowel disease: immediate and long-term consequences and outcomesDieter Hahnloser
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota, USA
Dis Colon Rectum 47:1127-35. 2004..The method of delivery should be dictated by obstetrical considerations. Pouch function and the incidence of complications in females with pregnancies seem largely unaffected long-term... - The management of complicated diverticulitisJennifer R Chapman
Francisco Skemp Hospital, 800 West Avenue South, La Crosse, WI 54601, USA
Adv Surg 40:285-97. 2006 - Management of Crohn's disease of the ileoanal pouch with infliximabJean-Frederic Colombel
Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Gastroenterol 98:2239-44. 2003..Good pouch function requires long term treatment with infliximab in most patients... - Impact of a multimedia e-learning module on colon cancer literacy: a community-based pilot studyStefan D Holubar
Department of Colon and Rectal Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Surg Res 156:305-11. 2009..We aimed to determine if an e-learning module could improve colon cancer literacy in a community-based cohort, while obtaining variability estimates for subsequent study... - Peutz-Jeghers syndrome: a study of long-term surgical morbidity and causes of mortalityY Nancy You
Division of Colorectal Surgery, Department of Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Fam Cancer 9:609-16. 2010.... - Meckel diverticulum: the Mayo Clinic experience with 1476 patients (1950-2002)John J Park
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
Ann Surg 241:529-33. 2005..If a selective approach is taken, we recommend removing all incidental Meckel diverticula that have any of the 4 features most commonly associated with symptomatic Meckel diverticulum... - Molecular biology of squamous cell carcinoma of the anus: a comparison of HIV-positive and HIV-negative patientsPascal Gervaz
Department of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
J Gastrointest Surg 8:1024-30; discussion 1031. 2004..These data suggest that immunosuppression may promote SCCA progression through an alternate pathway and that persistence of HPV infection within the anal canal may play a central role in this process... - Reoperative Crohn's surgery: tricks of the tradeRobert R Cima
Division of Colon and Rectal Surgery, Mayo Clinic College of Medicine, Mayo Clinic, Rochester, Minnesota
Clin Colon Rectal Surg 20:336-43. 2007..In this paper, we will review some of the important principles in operative and reoperative Crohn's surgery that can assist the surgeon when approaching these challenging cases... - Colorectal adenocarcinoma in cirrhotic patientsPascal Gervaz
Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, MN 55905, USA
J Am Coll Surg 196:874-9. 2003..CONCLUSIONS: Liver metastases from colorectal adenocarcinoma is infrequent (10%) in cirrhotic patients. The Child's classification, and not the TNM stage of the carcinoma, predicts the risk of postoperative death and longterm survival... - Advances in surgical approaches to Crohn's disease: minimally invasive surgery and biologic therapyStefan D Holubar
Clinical Research Fellow Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Expert Rev Clin Immunol 5:463-70. 2009.... - Intraoperative electron radiotherapy as a component of salvage therapy for patients with colorectal cancer and advanced nodal metastasesMichael G Haddock
Division of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
Int J Radiat Oncol Biol Phys 56:966-73. 2003..To define the survival rates and relapse patterns in patients with isolated advanced nodal metastases secondary to colorectal cancer, treated with curative intent using aggressive combined-modality treatment... - Melanoma metastatic to the colon: case series and review of the literature with outcome analysisDeron J Tessier
Department of Surgery, Division of Colon and Rectal Surgery, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Dis Colon Rectum 46:441-7. 2003..Survival of less than ten months is most accurately predicted by signs and symptoms of obstruction or perforation at presentation (P = 0.03)... - A different type of presacral tumor: extramedullary hematopoiesis: report of a caseJuan M Sarmiento
Division of Gastroenterologic and General Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
Dis Colon Rectum 46:683-5. 2003 - Fistulas to the urinary system in Crohn's disease: clinical features and outcomesCraig A Solem
Department of Internal Medicine, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA
Am J Gastroenterol 97:2300-5. 2002..The most helpful diagnostic tests were cystoscopy and CT of abdomen/pelvis. Surgery resulted in durable remission. Medical therapy for these fistulas deserves further study... - Prevention of postoperative abdominal adhesions by a novel, glycerol/sodium hyaluronate/carboxymethylcellulose-based bioresorbable membrane: a prospective, randomized, evaluator-blinded multicenter studyZane Cohen
Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Canada
Dis Colon Rectum 48:1130-9. 2005..Animal models did not predict these complications... - Reduction in adhesive small-bowel obstruction by Seprafilm adhesion barrier after intestinal resectionVictor W Fazio
Cleveland Clinic, Cleveland, Ohio, USA
Dis Colon Rectum 49:1-11. 2006..CONCLUSIONS: The overall bowel obstruction rate was unchanged; however, adhesive small-bowel obstruction requiring reoperation was significantly reduced by the use of Seprafilm, which was the only factor that predicted this outcome... - Alvimopan, for postoperative ileus following bowel resection: a pooled analysis of phase III studiesConor P Delaney
Division of Colorectal Surgery, University Hospitals of Cleveland, Cleveland, OH 44106 5047, USA
Ann Surg 245:355-63. 2007..To obtain further analysis regarding specific outcomes and alvimopan doses in bowel resection (BR) patients... - Postoperative upper and lower gastrointestinal recovery and gastrointestinal morbidity in patients undergoing bowel resection: pooled analysis of placebo data from 3 randomized controlled trialsConor P Delaney
Division of Colorectal Surgery, University Hospitals of Cleveland, 11100 Euclid Ave, Cleveland, OH 44106, USA
Am J Surg 191:315-9. 2006..This analysis examines gastrointestinal recovery in patients who underwent bowel resection (BR) in 3 recent trials... - A prospective, randomized, multicenter, controlled study of the safety of Seprafilm adhesion barrier in abdominopelvic surgery of the intestineDavid E Beck
Department of Colon and Rectal Surgery, Ochsner Clinic Foundation, New Orleans, Louisiana, 70121, USA
Dis Colon Rectum 46:1310-9. 2003..However, wrapping the suture or staple line of a fresh bowel anastomosis with Seprafilm should be avoided, because the data suggest that this practice may increase the risk of sequelae associated with anastomotic leak... - Comparison of reduced volume versus four liters sulfate-free electrolyte lavage solutions for colonoscopy colon cleansingJack A DiPalma
Division of Gastroenterology, University of South Alabama College of Medicine, Mobile, Alabama 36693, USA
Am J Gastroenterol 98:2187-91. 2003..CONCLUSIONS: Reduced volume preparation with 2 L SF-ELS and bisacodyl is safe and effective. Clinical symptoms from the reduced volume preparation are significantly reduced compared with traditional 4 L gut lavage... - Population-based incidence of complicated diverticular disease of the sigmoid colon based on gender and ageElizabeth J McConnell
Department of Surgery, Mayo Clinic Scottsdale, Scottsdale, Arizona, USA
Dis Colon Rectum 46:1110-4. 2003..03), whereas older males present with bleeding (P = 0.001). Young females present with perforation (P = 0.002), and older females present with chronic diverticulitis (P = 0.04) and stricture (P = 0.04)... - Benefits of povidone-iodine solution in colorectal operations: science or legendJirawat Pattana-arun
Colorectal Division, Chulalongkorn University, Bangkok, Thailand
Dis Colon Rectum 51:966-71. 2008..With limited prospective, randomized, controlled trials and insufficient data available, this article examines the safe and effective clinical applications of this solution for colorectal operations...