C Wider

Summary

Affiliation: Mayo Clinic
Country: USA

Publications

  1. pmc Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1: redefining DYT14 as DYT5
    C Wider
    Department of Neurology, Cannaday Building 2E, Mayo Clinic, San Pablo Road 4500, Jacksonville, FL 32246, USA
    Neurology 70:1377-83. 2008
  2. pmc Association of the MAPT locus with Parkinson's disease
    C Wider
    Department of Neuroscience, Mayo Clinic, Molecular Genetics Laboratory and Core, Morris K Udall Parkinsons Disease Research Center of Excellence, Jacksonville, FL 32224, USA
    Eur J Neurol 17:483-6. 2010
  3. pmc FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression
    Christian Wider
    Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA
    Mov Disord 24:455-9. 2009
  4. pmc GCH1 expression in human cerebellum from healthy individuals is not gender dependent
    Christian Wider
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurosci Lett 462:73-5. 2009
  5. ncbi Calbindin-1 association and Parkinson's disease
    A I Soto-Ortolaza
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
    Eur J Neurol 17:208-11. 2010
  6. ncbi GRN 3'UTR+78 C>T is not associated with risk for Parkinson's disease
    B Jasinska-Myga
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
    Eur J Neurol 16:909-11. 2009
  7. doi SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study
    C Wider
    Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Eur J Neurol 18:876-81. 2011
  8. doi Death-associated protein kinase 1 variation and Parkinson's disease
    J C Dachsel
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Eur J Neurol 18:1090-3. 2011
  9. pmc Characterization of DCTN1 genetic variability in neurodegeneration
    C Vilariño-Güell
    Molecular Genetics Laboratory and Core, Morris K Udall Parkinson s Disease Research Center of Excellence, Mayo Clinic, Department of Neuroscience, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Neurology 72:2024-8. 2009
  10. pmc Leukoencephalopathy with spheroids (HDLS) and pigmentary leukodystrophy (POLD): a single entity?
    C Wider
    Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurology 72:1953-9. 2009

Detail Information

Publications12

  1. pmc Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1: redefining DYT14 as DYT5
    C Wider
    Department of Neurology, Cannaday Building 2E, Mayo Clinic, San Pablo Road 4500, Jacksonville, FL 32246, USA
    Neurology 70:1377-83. 2008
    ..To report the study of a multigenerational Swiss family with dopa-responsive dystonia (DRD)...
  2. pmc Association of the MAPT locus with Parkinson's disease
    C Wider
    Department of Neuroscience, Mayo Clinic, Molecular Genetics Laboratory and Core, Morris K Udall Parkinsons Disease Research Center of Excellence, Jacksonville, FL 32224, USA
    Eur J Neurol 17:483-6. 2010
    ..Whilst an association between the tau gene (MAPT)-containing H1 haplotype and supranuclear gaze palsy (PSP) has long been recognized, the effect of H1 on risk for Parkinson's disease (PD) has remained more contentious...
  3. pmc FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expression
    Christian Wider
    Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA
    Mov Disord 24:455-9. 2009
    ..We found no evidence of association between FGF20 variability and PD risk, and no relationship between the rs12720208 genotype, FGF20 and alpha-synuclein protein levels...
  4. pmc GCH1 expression in human cerebellum from healthy individuals is not gender dependent
    Christian Wider
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurosci Lett 462:73-5. 2009
    ....
  5. ncbi Calbindin-1 association and Parkinson's disease
    A I Soto-Ortolaza
    Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
    Eur J Neurol 17:208-11. 2010
    ..Recently, an association was reported between the calcium buffer, calbindin (rs1805874) and risk of PD in a Japanese patient-control series...
  6. ncbi GRN 3'UTR+78 C>T is not associated with risk for Parkinson's disease
    B Jasinska-Myga
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
    Eur J Neurol 16:909-11. 2009
    ..rs5848 is located within a micro-RNA binding site and affects the expression of GRN...
  7. doi SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction study
    C Wider
    Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Eur J Neurol 18:876-81. 2011
    ..In the current study, we attempt to validate previously published findings, evaluating gene-gene interactions between SNCA, MAPT, and GSK3B in association with PD...
  8. doi Death-associated protein kinase 1 variation and Parkinson's disease
    J C Dachsel
    Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
    Eur J Neurol 18:1090-3. 2011
    ..The Lrrk2 protein is a member of the ROCO family, which also includes Lrrk1 and Dapk1. Functional genetic variants of the DAPK1 gene (rs4877365 and rs4878104) have been previously associated with Alzheimer's disease...
  9. pmc Characterization of DCTN1 genetic variability in neurodegeneration
    C Vilariño-Güell
    Molecular Genetics Laboratory and Core, Morris K Udall Parkinson s Disease Research Center of Excellence, Mayo Clinic, Department of Neuroscience, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Neurology 72:2024-8. 2009
    ....
  10. pmc Leukoencephalopathy with spheroids (HDLS) and pigmentary leukodystrophy (POLD): a single entity?
    C Wider
    Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurology 72:1953-9. 2009
    ..This supports HDLS and POLD being referred collectively as adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)...
  11. pmc Insights into the dynamics of hereditary diffuse leukoencephalopathy with axonal spheroids
    J A Van Gerpen
    Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA
    Neurology 71:925-9. 2008
    ..To report a new American family with hereditary diffuse leukoencephalopathy with spheroids (HDLS), including serial, presymptomatic and symptomatic, cranial MRIs from the proband...
  12. ncbi Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss family
    C Wider
    Department of Neurology, CHUV, Lausanne, Switzerland
    Parkinsonism Relat Disord 14:465-70. 2008
    ..To describe a large family with autosomal dominant parkinsonism...