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Genomes and GenesSpecies | C WiderSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Study of a Swiss dopa-responsive dystonia family with a deletion in GCH1: redefining DYT14 as DYT5C Wider
Department of Neurology, Cannaday Building 2E, Mayo Clinic, San Pablo Road 4500, Jacksonville, FL 32246, USA
Neurology 70:1377-83. 2008..To report the study of a multigenerational Swiss family with dopa-responsive dystonia (DRD)...
Association of the MAPT locus with Parkinson's diseaseC Wider
Department of Neuroscience, Mayo Clinic, Molecular Genetics Laboratory and Core, Morris K Udall Parkinsons Disease Research Center of Excellence, Jacksonville, FL 32224, USA
Eur J Neurol 17:483-6. 2010..Whilst an association between the tau gene (MAPT)-containing H1 haplotype and supranuclear gaze palsy (PSP) has long been recognized, the effect of H1 on risk for Parkinson's disease (PD) has remained more contentious...
FGF20 and Parkinson's disease: no evidence of association or pathogenicity via alpha-synuclein expressionChristian Wider
Department of Neuroscience, Mayo Clinic, Jacksonville, Florida 32224, USA
Mov Disord 24:455-9. 2009..We found no evidence of association between FGF20 variability and PD risk, and no relationship between the rs12720208 genotype, FGF20 and alpha-synuclein protein levels...
GCH1 expression in human cerebellum from healthy individuals is not gender dependentChristian Wider
Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
Neurosci Lett 462:73-5. 2009....
Calbindin-1 association and Parkinson's diseaseA I Soto-Ortolaza
Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA
Eur J Neurol 17:208-11. 2010..Recently, an association was reported between the calcium buffer, calbindin (rs1805874) and risk of PD in a Japanese patient-control series...
GRN 3'UTR+78 C>T is not associated with risk for Parkinson's diseaseB Jasinska-Myga
Department of Neuroscience, Mayo Clinic, Jacksonville, FL 32224, USA
Eur J Neurol 16:909-11. 2009..rs5848 is located within a micro-RNA binding site and affects the expression of GRN...
SNCA, MAPT, and GSK3B in Parkinson disease: a gene-gene interaction studyC Wider
Division of Neurogenetics, Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
Eur J Neurol 18:876-81. 2011..In the current study, we attempt to validate previously published findings, evaluating gene-gene interactions between SNCA, MAPT, and GSK3B in association with PD...
Death-associated protein kinase 1 variation and Parkinson's diseaseJ C Dachsel
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA
Eur J Neurol 18:1090-3. 2011..The Lrrk2 protein is a member of the ROCO family, which also includes Lrrk1 and Dapk1. Functional genetic variants of the DAPK1 gene (rs4877365 and rs4878104) have been previously associated with Alzheimer's disease...
Characterization of DCTN1 genetic variability in neurodegenerationC Vilariño-Güell
Molecular Genetics Laboratory and Core, Morris K Udall Parkinson s Disease Research Center of Excellence, Mayo Clinic, Department of Neuroscience, 4500 San Pablo Road, Jacksonville, FL 32224, USA
Neurology 72:2024-8. 2009....
Leukoencephalopathy with spheroids (HDLS) and pigmentary leukodystrophy (POLD): a single entity?C Wider
Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA
Neurology 72:1953-9. 2009..This supports HDLS and POLD being referred collectively as adult-onset leukoencephalopathy with axonal spheroids and pigmented glia (ALSP)...
Insights into the dynamics of hereditary diffuse leukoencephalopathy with axonal spheroidsJ A Van Gerpen
Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA
Neurology 71:925-9. 2008..To report a new American family with hereditary diffuse leukoencephalopathy with spheroids (HDLS), including serial, presymptomatic and symptomatic, cranial MRIs from the proband...
Autosomal dominant dopa-responsive parkinsonism in a multigenerational Swiss familyC Wider
Department of Neurology, CHUV, Lausanne, Switzerland
Parkinsonism Relat Disord 14:465-70. 2008..To describe a large family with autosomal dominant parkinsonism...
