Research Topics
| R D WhiteSummaryAffiliation: Mayo Clinic Country: USA Publications
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Publications
Long-term subjective memory function in ventricular fibrillation out-of-hospital cardiac arrest survivors resuscitated by early defibrillationT Jared Bunch
Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA
Resuscitation 60:189-95. 2004..There were more long-term-memory complaints in younger patients. Patients with higher long-term quality-of-life score have fewer memory complaints...
High discharge survival rate after out-of-hospital ventricular fibrillation with rapid defibrillation by police and paramedicsR D White
Mayo Clinic and Medical School, Rochester, Minnesota
Ann Emerg Med 28:480-5. 1996..To assess outcome in patients with ventricular fibrillation (VF) treated by defibrillator-equipped police and emergency medical technician-paramedics in an advanced life support (ALS) emergency medical services (EMS) system...
Refibrillation, resuscitation and survival in out-of-hospital sudden cardiac arrest victims treated with biphasic automated external defibrillatorsRoger D White
Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 55:17-23. 2002..The incidence and course of refibrillation, and its relation to patient outcomes, has not been previously described in the context of treatment of out-of-hospital SCA with biphasic waveform automated external defibrillators (AEDs)...
Transthoracic impedance does not affect defibrillation, resuscitation or survival in patients with out-of-hospital cardiac arrest treated with a non-escalating biphasic waveform defibrillatorRoger D White
Department of Anesthesiology, The Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 64:63-9. 2005....
Evolution of a community-wide early defibrillation programme experience over 13 years using police/fire personnel and paramedics as respondersRoger D White
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 65:279-83. 2005..Following the trial, the program was expanded as the city grew in population and area. In 1998 firefighters also were equipped with AEDs, bringing to a total 18 AEDs with police and fire personnel, in addition to paramedic capability...
Neurologic recovery following prolonged out-of-hospital cardiac arrest with resuscitation guided by continuous capnographyRoger D White
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
Mayo Clin Proc 86:544-8. 2011..To our knowledge, this is the longest duration of pulselessness in an out-of-hospital arrest with a good outcome. Good pulmonary blood flow was documented throughout by end-tidal carbon dioxide measurements...
Technologic advances and program initiatives in public access defibrillation using automated external defibrillatorsR D White
Department of Anesthesiology, Mayo Medical School and Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Curr Opin Crit Care 7:145-51. 2001....
Patient outcomes following defibrillation with a low energy biphasic truncated exponential waveform in out-of-hospital cardiac arrestR D White
Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 49:9-14. 2001..MATERIALS and..
Biphasic truncated exponential waveform defibrillationR D White
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905, USA
Prehosp Emerg Care 3:283-9. 1999..For future research, the terms associated with defibrillation should be standardized and used uniformly by all investi-gators. In particular, there should be an agreed-upon definition of shock efficacy...
Waveforms for defibrillation and cardioversion: recent experimental and clinical studiesRoger D White
Department of Anesthesiology, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
Curr Opin Crit Care 10:202-7. 2004..At the same time, it has led to the development and clinical use of biphasic waveforms of several different designs. Finally, other types of waveforms, primarily triphasic, have entered experimental evaluation...
New concepts in transthoracic defibrillationRoger D White
City of Rochester Early Defibrillation Program, Mayo Medical School, 200 First Street SW, Rochester, MN 55905, USA
Emerg Med Clin North Am 20:785-807. 2002..This represents a major challenge in defibrillation research...
Seven years' experience with early defibrillation by police and paramedics in an emergency medical services systemR D White
Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
Resuscitation 39:145-51. 1998..Short time differences, on the order of 1 min, are significant determinants of both immediate response to shocks and discharge survival...
Recurrent ventricular fibrillation in out-of-hospital cardiac arrest after defibrillation by police and firefighters: implications for automated external defibrillator usersErik P Hess
Department of Emergency Medicine, Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN, USA
Crit Care Med 32:S436-9. 2004..Thus, vigilance for recurrent VF is essential to ensure the survival of patients who are in the care of first responders, even after initial restoration of pulses with shocks...
Ventricular fibrillation in Rochester, Minnesota: experience over 18 yearsDipti A Agarwal
Department of Emergency Medicine, Division of Emergency Medicine Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Resuscitation 80:1253-8. 2009..7% to 39.9%, with only a few cities reporting rates higher than this. We report outcomes and incidence of VF OHCA over 18 years in a medium-sized city incorporating an aggressive approach to OHCA...
Impact of age on long-term survival and quality of life following out-of-hospital cardiac arrestT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Crit Care Med 32:963-7. 2004..The survival, although high, in older patients is less than that in age-matched healthy controls, and physical and emotional quality of life scores are decreased...
Sex differences in outcome after ventricular fibrillation in out-of-hospital cardiac arrestSrijoy Mahapatra
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic College of Medicine, 200 First Street, SW, Rochester, MN 55902, USA
Resuscitation 65:197-202. 2005..CONCLUSION: Women are more likely to survive to hospital admission following an OHCA. However, admitted women less likely to survive their hospital stay. Long-term survival and QOL are equally favorable in both sexes...
Ventricular fibrillation is not provoked by chest compression during post-shock organized rhythms in out-of-hospital cardiac arrestErik P Hess
Resident in Emergency Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 66:7-11. 2005..However, during post-shock OR VF recurred unrelated to CC in most instances. Thus, resumption of CC immediately after shocks that restore an OR is unlikely to provoke recurrent VF, and resumption of CC need not be delayed...
A comparative analysis of short- and long-term outcomes after ventricular fibrillation out-of-hospital cardiac arrest in patients with ischemic and nonischemic heart diseaseT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 98:857-60. 2006..Nonetheless, in patients with IHD, use of an implantable cardioverter-defibrillator and statin therapy were associated with higher long-term survival rates...
Trends in treated ventricular fibrillation in out-of-hospital cardiac arrest: ischemic compared to non-ischemic heart diseaseT Jared Bunch
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 67:51-4. 2005..The relative increasing incidence of non-ischemic VF OHCA suggests that more efforts are required to minimize mortality in this cohort population...
Opportunities to prevent sudden out-of-hospital death due to coronary heart disease in a communityLambert A Wu
Department of Internal Medicine, Mayo Clinic and Foundation, 200 1st Street SW, Rochester, MN 55905, USA
Resuscitation 56:55-8. 2003..Intervening successfully to reduce the burden of sudden out-of-hospital death due to coronary heart disease (OHCD) requires knowledge of where these deaths occur and whether they are observed by bystanders...
New insights into the predictors of left atrial stunning after successful direct-current cardioversion of atrial fibrillation and flutterRowlens M Melduni
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Soc Echocardiogr 21:848-54. 2008..Direct-current cardioversion (DCCV) of atrial fibrillation and atrial flutter commonly causes post-DCCV left atrial (LA) stunning (LAS), which may potentiate thromboembolic complications. Data on LAS determinants are inconclusive...
Optimizing survival from out-of-hospital cardiac arrestErik P Hess
Department of Emergency Medicine, Division of Emergency Medicine Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
J Cardiovasc Electrophysiol 21:590-5. 2010..Optimizing cardiac arrest survival requires a team effort between EMS directors, emergency physicians, cardiologists, hospital leadership, and the public...
Long-term outcomes of out-of-hospital cardiac arrest after successful early defibrillationT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
N Engl J Med 348:2626-33. 2003..The quality of life among the majority of survivors is similar to that of the general population...
Body weight does not affect defibrillation, resuscitation, or survival in patients with out-of-hospital cardiac arrest treated with a nonescalating biphasic waveform defibrillatorRoger D White
The Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 32:S387-92. 2004..CONCLUSIONS: Overweight patients were defibrillated by the biphasic waveform used in this study at high rates, with a fixed energy of 150 J, and without energy escalation...
Does left atrial appendage peak emptying flow velocity predict the electrical energy required to achieve successful direct-current cardioversion in patients with persistent atrial fibrillation?Rowlens M Melduni
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Soc Echocardiogr 20:1004-8. 2007..We tested the hypothesis that LAAEV can predict optimal energy required for DCCV in persistent AF (>48 hours)...
Acquired long QT syndrome and elective anesthesia in childrenTimothy B Curry
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA
Paediatr Anaesth 16:471-8. 2006..Additionally, this case emphasizes the need to inquire about the use of supplements and naturopathic medications, even in children, that may have life-threatening side effects or interactions with anesthetic agents...
Outcomes and in-hospital treatment of out-of-hospital cardiac arrest patients resuscitated from ventricular fibrillation by early defibrillationT Jared Bunch
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
Mayo Clin Proc 79:613-9. 2004..By the end of the 10-year study, more patients were receiving antiarrhythmic therapy, in particular ICD implantation, after hospital admission. Overall, the long-term survival in patients with VF OHCA is favorable...
A high peak current 150-J fixed-energy defibrillation protocol treats recurrent ventricular fibrillation (VF) as effectively as initial VFErik P Hess
Department of Emergency Medicine, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Resuscitation 79:28-33. 2008..We tested the hypothesis that the frequency of shock success differs between initial and recurrent episodes of ventricular fibrillation (VF)...
Admission predictors of in-hospital mortality and subsequent long-term outcome in survivors of ventricular fibrillation out-of-hospital cardiac arrest: a population-based studyThomas J Bunch
Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Cardiology 102:41-7. 2004..Identification of these variables may provide utility in identifying those at high-risk of subsequent mortality after resuscitation...
Increased prevalence of sustained return of spontaneous circulation following transition to biphasic waveform defibrillationErik P Hess
Department of Emergency Medicine, College of Medicine, Mayo Clinic, Rochester, MN, United States
Resuscitation 77:39-45. 2008....
Improved retention of the EMS activation component (EMSAC) in adult CPR educationM C Bilger
Mayo School of Health Related Sciences, Nurse Anesthesia Program, Rochester, MN 55905, USA
Resuscitation 35:219-24. 1997..18). We conclude that use of the model-telephone improved EMSAC retention significantly overall except in the < 30 year-old age group. We recommend using the model-telephone in future adult CPR classes...
Trends in treated ventricular fibrillation out-of-hospital cardiac arrest: a 17-year population-based studyT Jared Bunch
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Heart Rhythm 1:255-9. 2004..Sudden death preventive strategies are multifactorial. These observations suggest that ICD termination of potentially lethal ventricular arrhythmias may contribute to the lower incidence of VF out-of-hospital cardiac arrest...
Management of ventricular fibrillation or unstable ventricular tachycardia in patients with congenital long-QT syndrome: a suggested modification to ACLS guidelinesJason H Homme
Department of Pediatric and Adolescent Medicine/Division of Pediatric Cardiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 59:111-5. 2003..A clarified ACLS algorithm is proposed...
Out-of-hospital cardiac arrest in patients with cardiac amyloidosis: presenting rhythms, management and outcomes in four patientsErik P Hess
Emergency Medicine, Mayo Clinic, Rochester, MN, USA
Resuscitation 60:105-11. 2004..We describe here our experience with four patients with AL who had an OHCA, including presenting rhythms, interventions, and outcomes...
Prediction of short- and long-term outcomes by electrocardiography in survivors of out-of-hospital cardiac arrestT Jared Bunch
Division of Cardiology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA
Resuscitation 63:137-43. 2004....
Early direct coronary angioplasty in survivors of out-of-hospital cardiac arrestPaul C Keelan
Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Am J Cardiol 91:1461-3, A6. 2003
Get the dataR D White
Mayo Medical School, Rochester, Minn, USA
JEMS 26:S4-5. 2001....
Outcomes after ventricular fibrillation out-of-hospital cardiac arrest: expanding the chain of survivalT Jared Bunch
Department of Internal Medicine and Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 80:774-82. 2005..Broadening the focus of the chain of survival to include in-hospital and long-term care will further improve favorable outcomes achieved in an early defibrillation program...
Automated external defibrillators and first responders: a satisfaction surveyLaurence D Prina
Department of Anesthesiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 53:171-7. 2002..Restoration of a pulse was clearly a factor responsible for a higher satisfaction. This positive attitude should encourage further implementation of early defibrillation programs in non-medical first responder settings...
Survival of a neurologically intact patient with subarachnoid hemorrhage and cardiopulmonary arrestErik P Hess
Department of Emergency Medicine Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 80:1073-6. 2005..Prompt defibrillation of SAH-induced ventricular fibrillation and timely neurologic intervention are essential for good neurologic outcome...
Association of body weight with total mortality and with ICD shocks among survivors of ventricular fibrillation in out-of-hospital cardiac arrestT Jared Bunch
Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
Resuscitation 77:351-5. 2008..Studies have shown an association between obesity and total mortality among people with and without coronary artery disease. This study reviews outcomes among obese survivors of ventricular fibrillation in out-of-hospital cardiac arrest...
Epidemiology, trends, and outcome of out-of-hospital cardiac arrest of non-cardiac originErik P Hess
Mayo Clinic College of Medicine, Rochester, MN, USA
Resuscitation 72:200-6. 2007..Over the past decade, the incidence of VF OHCA has declined. The aims of this study were to describe the epidemiology of OHCA of non-cardiac origin in Olmsted County MN and to determine the trends that have occurred over time...
Comparative efficacy of monophasic and biphasic waveforms for transthoracic cardioversion of atrial fibrillation and atrial flutterOsnat T Gurevitz
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Am Heart J 149:316-21. 2005..CONCLUSION: When used to cardiovert atrial arrhythmias, the rectilinear biphasic waveform was associated with higher success rates and lower cumulative energies than the monophasic damped sine waveform...
Prospective, randomized comparison of two biphasic waveforms for the efficacy and safety of transthoracic biphasic cardioversion of atrial fibrillationFaisal Alatawi
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
Heart Rhythm 2:382-7. 2005..No significant difference in efficacy was observed between BR and BTE waveforms. Impedance was not an important determinant of success for either biphasic waveform...
Prognostic implication of early ejection fraction on long-term mortality and quality of life following out-of-hospital cardiac arrestAkbar H Khan
Department of Internal Medicine, Mayo Clinic, Rochester, Minnesota, USA
Am J Cardiol 93:1027-30. 2004..However, overall long-term quality-of-life was favorable and independent of the ejection fraction...
Anesthesia for patients with congenital long QT syndromeSusan J Kies
Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
Anesthesiology 102:204-10. 2005..Certain drugs, including anesthetic agents, are known to contribute to QT prolongation. After reviewing the literature the authors give recommendations for the anesthetic management of these patients in the perioperative period...
Outcome prediction for guidance of initial resuscitation protocol: Shock first or CPR firstDavid E Snyder
Philips Medical Systems, Seattle, WA, USA
Resuscitation 72:45-51. 2007..An objective measure of potential responsiveness to defibrillation could help decide optimal initial therapy...
Law Enforcement Agency Defibrillation (LEA-D): proceedings of the National Center for Early Defibrillation Police AED Issues ForumVincent N Mosesso
National Center for Early Defibrillation, University of Pittsburgh, Department of Emergency Medicine, Pennsylvania 15213, USA
Prehosp Emerg Care 6:273-82. 2002..It is time for law enforcement agency defibrillation to become the rule, not the exception...
Law Enforcement Agency Defibrillation (LEA-D): position statement and best practices recommendations from the National Center for Early DefibrillationMary M Newman
National Center for Early Defibrillation, University of Pittsburgh, Department of Emergency Medicine, Pennsylvania 15213, USA
Prehosp Emerg Care 6:346-7. 2002
Home use of automated external defibrillators for sudden cardiac arrestGust H Bardy
Seattle Institute for Cardiac Research, Seattle, WA 98103 4819, USA
N Engl J Med 358:1793-804. 2008..Consequently, home use of an automated external defibrillator (AED) might offer an opportunity to improve survival for patients at risk...
Hands-only (compression-only) cardiopulmonary resuscitation: a call to action for bystander response to adults who experience out-of-hospital sudden cardiac arrest: a science advisory for the public from the American Heart Association Emergency CardiovascMichael R Sayre
Ohio State University, USA
Circulation 117:2162-7. 2008
Incidence of EMS-treated out-of-hospital cardiac arrest in the United StatesThomas D Rea
Department of Medicine, University of Washington, USA
Resuscitation 63:17-24. 2004..The aim of the investigation was to determine a representative national incidence of emergency medical services (EMS)-treated all-rhythm and ventricular fibrillation (VF) SCA as well as survival...
A simplified approach to the challenging problem of resuscitation of patients who present in pulseless electrical activityT Jared Bunch
Crit Care Med 36:619-20. 2008
Letter by Tang et al regarding article, "BIPHASIC trial: a randomized comparison of fixed lower versus escalating higher energy levels for defibrillation in out-of-hospital cardiac arrest"Wanchun Tang
Circulation 116:e522; author reply e523. 2007
Clinical experience with a low-energy pulsed biphasic waveform in out-of-hospital cardiac arrestJean Philippe Didon
Schiller Médical SAS, 4 rue L Pasteur, F 67160 Wissembourg, France
Resuscitation 76:350-3. 2008..These observations demonstrate a rate of first shock success in termination of ventricular fibrillation comparable to that reported with biphasic truncated exponential waveforms in out-of-hospital cardiac arrest...
Defibrillator and dispatch center clock synchronization is essential for time-sensitive treatment of cardiac arrestErik P Hess
Resuscitation 68:435-6. 2006
2005 American Heart Association Guidelines for Cardiopulmonary Resuscitation: physiologic and educational rationale for changesRoger D White
Mayo Clin Proc 81:736-40. 2006
Assessment of a three-phase model of out-of-hospital cardiac arrest in patients with ventricular fibrillationRonna L Campbell
Mayo Clinic College of Medicine, MN, United States
Resuscitation 73:229-35. 2007..The aim of this study was to assess the relationship between call-to-shock time, bystander CPR (BCPR), and cardiac arrest outcomes...
Preventing sudden death with n-3 (omega-3) fatty acids and defibrillatorsThomas E Kottke
The Heart Center, Regions Hospital, St Paul, Minnesota 55101, USA
Am J Prev Med 31:316-323. 2006....
Analysis of the ventricular fibrillation waveform in refibrillationJames K Russell
Philips Medical Systems, Seattle, Washington, USA
Crit Care Med 34:S432-7. 2006..It has advantages over guidance based on individual or aggregate system response times...
Rationale and design of the Home Automatic External Defibrillator Trial (HAT)Gust H Bardy
The Seattle Institute for Cardiac Research, Seattle, WA 98103 4819, USA
Am Heart J 155:445-54. 2008..The results of the trial should be available in mid 2008...
Decision making with biomarkers after cardiac arrest: are we there yet?T Jared Bunch
Crit Care Med 35:1411-2. 2007
